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3-phosphoglycerate and Neoplasms

3-phosphoglycerate has been researched along with Neoplasms in 8 studies

3-phosphoglycerate : An organic anion obtained by deprotonation of at least one of the acidic groups of 3-phosphoglyceric acid.

Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Research Excerpts

ExcerptRelevanceReference
"We used datasets from the Cancer Cell Line Encyclopedia (CCLE) phase II project and treated metabolomic data as tensor predictors and data on gene expression of metabolic enzymes as confounding covariates."1.91Controlling the confounding effect of metabolic gene expression to identify actual metabolite targets in microsatellite instability cancers. ( Huang, TH; Li, CI; Lin, PC; Shen, MR; Tsai, YS; Yeh, YM, 2023)
"It is unclear how cancer cells coordinate glycolysis and biosynthesis to support rapidly growing tumors."1.38Phosphoglycerate mutase 1 coordinates glycolysis and biosynthesis to promote tumor growth. ( Alečković, M; Arellano, ML; Boggon, TJ; Chen, GZ; Chen, J; Dai, Q; DeBerardinis, RJ; Elf, S; Fan, J; Gu, TL; He, C; Hitosugi, T; Jin, P; Kang, HB; Kang, S; Kang, Y; Khoury, HJ; Khuri, FR; Lee, BH; LeRoy, G; Lonial, S; Luan, CH; Muller, S; Owonikoko, TK; Seo, JH; Shan, C; Shin, DM; Sudderth, JA; Xie, J; Ye, K; Zhang, L; Zhou, L, 2012)
"Proliferating cells, including cancer cells, require altered metabolism to efficiently incorporate nutrients such as glucose into biomass."1.36Evidence for an alternative glycolytic pathway in rapidly proliferating cells. ( Amador-Noguez, D; Asara, JM; Cantley, LC; Christofk, HR; Heffron, GJ; Locasale, JW; Rabinowitz, JD; Sharfi, H; Swanson, KD; Vander Heiden, MG; Wagner, G, 2010)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (62.50)24.3611
2020's3 (37.50)2.80

Authors

AuthorsStudies
Li, CI1
Yeh, YM1
Tsai, YS1
Huang, TH1
Shen, MR1
Lin, PC1
Jin, C1
Zhu, X1
Wu, H1
Wang, Y3
Hu, X1
Fareed, MM1
El-Esawi, MA1
El-Ballat, EM1
Batiha, GE1
Rauf, A1
El-Demerdash, FM1
Alhumaydhi, FA1
Alsagaby, SA1
Sharif, F1
Rasul, A1
Ashraf, A1
Hussain, G1
Younis, T1
Sarfraz, I1
Chaudhry, MA1
Bukhari, SA1
Ji, XY1
Selamoglu, Z1
Ali, M1
Hitosugi, T2
Zhou, L2
Fan, J2
Elf, S2
Zhang, L2
Xie, J2
Gu, TL2
Alečković, M2
LeRoy, G2
Kang, Y2
Kang, HB2
Seo, JH2
Shan, C2
Jin, P2
Gong, W1
Lonial, S2
Arellano, ML2
Khoury, HJ2
Chen, GZ2
Shin, DM2
Khuri, FR2
Boggon, TJ2
Kang, S2
He, C2
Chen, J2
Cai, WS1
Chen, L1
Wang, G1
Vander Heiden, MG1
Locasale, JW1
Swanson, KD1
Sharfi, H1
Heffron, GJ1
Amador-Noguez, D1
Christofk, HR1
Wagner, G1
Rabinowitz, JD1
Asara, JM1
Cantley, LC1
Dai, Q1
Sudderth, JA1
DeBerardinis, RJ1
Luan, CH1
Muller, S1
Owonikoko, TK1
Lee, BH1
Ye, K1

Reviews

1 review available for 3-phosphoglycerate and Neoplasms

ArticleYear
Phosphoglycerate mutase 1 in cancer: A promising target for diagnosis and therapy.
    IUBMB life, 2019, Volume: 71, Issue:10

    Topics: Cell Proliferation; Glyceric Acids; Glycolysis; Humans; Molecular Targeted Therapy; Neoplasms; Phosp

2019

Other Studies

7 other studies available for 3-phosphoglycerate and Neoplasms

ArticleYear
Controlling the confounding effect of metabolic gene expression to identify actual metabolite targets in microsatellite instability cancers.
    Human genomics, 2023, 03-06, Volume: 17, Issue:1

    Topics: Biomarkers, Tumor; Gene Expression; Glyceric Acids; Humans; Microsatellite Instability; Neoplasms; S

2023
Perturbation of phosphoglycerate kinase 1 (PGK1) only marginally affects glycolysis in cancer cells.
    The Journal of biological chemistry, 2020, 05-08, Volume: 295, Issue:19

    Topics: A549 Cells; Diphosphoglyceric Acids; Glucose; Glyceric Acids; Glycolysis; HeLa Cells; Humans; Kineti

2020
    BioMed research international, 2021, Volume: 2021

    Topics: Antineoplastic Agents; Arginine; Binding Sites; Cell Movement; Cell Proliferation; Computer Simulati

2021
Tyr26 phosphorylation of PGAM1 provides a metabolic advantage to tumours by stabilizing the active conformation.
    Nature communications, 2013, Volume: 4

    Topics: 2,3-Diphosphoglycerate; Amino Acid Sequence; Animals; Cell Line, Tumor; Cell Proliferation; Enzyme S

2013
Molecular dynamics simulation reveals how phosphorylation of tyrosine 26 of phosphoglycerate mutase 1 upregulates glycolysis and promotes tumor growth.
    Oncotarget, 2017, Feb-14, Volume: 8, Issue:7

    Topics: 2,3-Diphosphoglycerate; Algorithms; Amino Acid Sequence; Glyceric Acids; Glycolysis; Humans; Hydroge

2017
Evidence for an alternative glycolytic pathway in rapidly proliferating cells.
    Science (New York, N.Y.), 2010, Sep-17, Volume: 329, Issue:5998

    Topics: Adenosine Triphosphate; Animals; Cell Line; Cell Line, Tumor; Cell Proliferation; Female; Glucose; G

2010
Phosphoglycerate mutase 1 coordinates glycolysis and biosynthesis to promote tumor growth.
    Cancer cell, 2012, Nov-13, Volume: 22, Issue:5

    Topics: Animals; Binding, Competitive; Cell Line, Tumor; Cell Proliferation; Enzyme Activation; Gene Knockdo

2012