Page last updated: 2024-10-15

3-phenylpropionic acid and Propionic Acidemia

3-phenylpropionic acid has been researched along with Propionic Acidemia in 1 studies

3-phenylpropionic acid: RN given refers to parent cpd
3-phenylpropionic acid : A monocarboxylic acid that is propionic acid substituted at position 3 by a phenyl group.

Propionic Acidemia: Autosomal recessive metabolic disorder caused by mutations in PROPIONYL-COA CARBOXYLASE genes that result in dysfunction of branch chain amino acids and of the metabolism of certain fatty acids. Neonatal clinical onset is characterized by severe metabolic acidemia accompanied by hyperammonemia, HYPERGLYCEMIA, lethargy, vomiting, HYPOTONIA; and HEPATOMEGALY. Survivors of the neonatal onset propionic acidemia often show developmental retardation, and intolerance to dietary proteins. Late-onset form of the disease shows mild mental and/or developmental retardation, sometimes without metabolic acidemia.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (100.00)2.80

Authors

AuthorsStudies
Armstrong, AJ1
Henke, BR1
Collado, MS1
Taylor, JM1
Pourtaheri, TD1
Dillberger, JE1
Roper, TD1
Wamhoff, BR1
Olson, MW1
Figler, RA1
Hoang, SA1
Reardon, JE1
Johns, BA1

Other Studies

1 other study available for 3-phenylpropionic acid and Propionic Acidemia

ArticleYear
Identification of 2,2-Dimethylbutanoic Acid (HST5040), a Clinical Development Candidate for the Treatment of Propionic Acidemia and Methylmalonic Acidemia.
    Journal of medicinal chemistry, 2021, 04-22, Volume: 64, Issue:8

    Topics: Acyl Coenzyme A; Amino Acid Metabolism, Inborn Errors; Animals; Area Under Curve; Butyrates; Cells,

2021