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3-nitropropionic acid and Striatonigral Atrophy

3-nitropropionic acid has been researched along with Striatonigral Atrophy in 5 studies

3-nitropropionic acid: succinate dehydrogenase inactivator; biosynthesized by FABACEAE plants from ASPARAGINE
3-nitropropanoic acid : A C-nitro compound that is propanoic acid in which one of the methyl hydrogens has been replaced by a nitro group.

Research Excerpts

ExcerptRelevanceReference
"A levodopa-responsive parkinsonism emerged in all MPTP-treated monkeys."5.31Dystonia is predictive of subsequent altered dopaminergic responsiveness in a chronic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine+3-nitropropionic acid model of striatonigral degeneration in monkeys. ( Bioulac, B; Fernagut, PO; Ghorayeb, I; Stefanova, N; Tison, F; Wenning, GK, 2002)
"A levodopa-responsive parkinsonism emerged in all MPTP-treated monkeys."1.31Dystonia is predictive of subsequent altered dopaminergic responsiveness in a chronic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine+3-nitropropionic acid model of striatonigral degeneration in monkeys. ( Bioulac, B; Fernagut, PO; Ghorayeb, I; Stefanova, N; Tison, F; Wenning, GK, 2002)
"We developed a primate model of striatonigral degeneration (SND), the neuropathology underlying levodopa-unresponsive parkinsonism associated with multiple systemic atrophy (MSA-P), by sequential systemic administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and 3-nitropropionic acid (3NP) in a Macaca fascicularis monkey."1.31Toward a primate model of L-dopa-unresponsive parkinsonism mimicking striatonigral degeneration. ( Aubert, I; Bezard, E; Fernagut, PO; Ghorayeb, I; Poewe, W; Tison, F; Wenning, GK, 2000)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ghorayeb, I2
Fernagut, PO4
Stefanova, N2
Wenning, GK3
Bioulac, B2
Tison, F4
Puschban, Z1
Brouillet, E2
Reindl, M1
Jellinger, KA1
Poewe, W2
Diguet, E1
Lastres-Becker, I1
Bizat, N1
Boyer, F1
Hantraye, P1
Fernández-Ruiz, J1
Aubert, I1
Bezard, E1

Other Studies

5 other studies available for 3-nitropropionic acid and Striatonigral Atrophy

ArticleYear
Dystonia is predictive of subsequent altered dopaminergic responsiveness in a chronic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine+3-nitropropionic acid model of striatonigral degeneration in monkeys.
    Neuroscience letters, 2002, Dec-19, Volume: 335, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antiparkinson Agents; Corpus Striatum; Diseas

2002
Neuropathological and behavioral changes induced by various treatment paradigms with MPTP and 3-nitropropionic acid in mice: towards a model of striatonigral degeneration (multiple system atrophy).
    Acta neuropathologica, 2003, Volume: 106, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Behavior, Animal; Brain; Disease Models, Anim

2003
MPTP potentiates 3-nitropropionic acid-induced striatal damage in mice: reference to striatonigral degeneration.
    Experimental neurology, 2004, Volume: 185, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Behavior, Animal; Cell Count; Corpus Striatum

2004
Potential involvement of cannabinoid receptors in 3-nitropropionic acid toxicity in vivo.
    Neuroreport, 2004, Oct-25, Volume: 15, Issue:15

    Topics: Animals; Autoradiography; Convulsants; Disease Models, Animal; Dopamine; Dronabinol; Drug Administra

2004
Toward a primate model of L-dopa-unresponsive parkinsonism mimicking striatonigral degeneration.
    Movement disorders : official journal of the Movement Disorder Society, 2000, Volume: 15, Issue:3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antiparkinson Agents; Brain Mapping; Corpus S

2000