3-nitropropionic acid has been researched along with Parkinsonian Disorders in 7 studies
3-nitropropionic acid: succinate dehydrogenase inactivator; biosynthesized by FABACEAE plants from ASPARAGINE
3-nitropropanoic acid : A C-nitro compound that is propanoic acid in which one of the methyl hydrogens has been replaced by a nitro group.
Parkinsonian Disorders: A group of disorders which feature impaired motor control characterized by bradykinesia, MUSCLE RIGIDITY; TREMOR; and postural instability. Parkinsonian diseases are generally divided into primary parkinsonism (see PARKINSON DISEASE), secondary parkinsonism (see PARKINSON DISEASE, SECONDARY) and inherited forms. These conditions are associated with dysfunction of dopaminergic or closely related motor integration neuronal pathways in the BASAL GANGLIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A levodopa-responsive parkinsonism emerged in all MPTP-treated monkeys." | 5.31 | Dystonia is predictive of subsequent altered dopaminergic responsiveness in a chronic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine+3-nitropropionic acid model of striatonigral degeneration in monkeys. ( Bioulac, B; Fernagut, PO; Ghorayeb, I; Stefanova, N; Tison, F; Wenning, GK, 2002) |
| "A levodopa-responsive parkinsonism emerged in all MPTP-treated monkeys." | 1.31 | Dystonia is predictive of subsequent altered dopaminergic responsiveness in a chronic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine+3-nitropropionic acid model of striatonigral degeneration in monkeys. ( Bioulac, B; Fernagut, PO; Ghorayeb, I; Stefanova, N; Tison, F; Wenning, GK, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (85.71) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Park, HJ | 1 |
| Bang, G | 1 |
| Lee, BR | 1 |
| Kim, HO | 1 |
| Lee, PH | 1 |
| Ghorayeb, I | 1 |
| Fernagut, PO | 3 |
| Stefanova, N | 1 |
| Wenning, GK | 1 |
| Bioulac, B | 1 |
| Tison, F | 3 |
| Klivenyi, P | 2 |
| Starkov, AA | 1 |
| Calingasan, NY | 1 |
| Gardian, G | 2 |
| Browne, SE | 1 |
| Yang, L | 2 |
| Bubber, P | 1 |
| Gibson, GE | 1 |
| Patel, MS | 1 |
| Beal, MF | 2 |
| Diguet, E | 2 |
| Wei, X | 1 |
| Du, Y | 1 |
| Rouland, R | 1 |
| Gross, C | 1 |
| Bezard, E | 1 |
| Siwek, D | 1 |
| Starkov, A | 1 |
| Cleren, C | 1 |
| Ferrante, RJ | 1 |
| Kowall, NW | 1 |
| Abeliovich, A | 1 |
| Nakahara, T | 1 |
| Yamamoto, T | 1 |
| Endo, K | 1 |
| Kayama, H | 1 |
| Labattu, B | 1 |
7 other studies available for 3-nitropropionic acid and Parkinsonian Disorders
| Article | Year |
|---|---|
Neuroprotective effect of human mesenchymal stem cells in an animal model of double toxin-induced multiple system atrophy parkinsonism.
Topics: Animals; bcl-2-Associated X Protein; Corpus Striatum; Cytochromes c; Disease Models, Animal; Humans; | 2011 |
Dystonia is predictive of subsequent altered dopaminergic responsiveness in a chronic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine+3-nitropropionic acid model of striatonigral degeneration in monkeys.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antiparkinson Agents; Corpus Striatum; Diseas | 2002 |
Mice deficient in dihydrolipoamide dehydrogenase show increased vulnerability to MPTP, malonate and 3-nitropropionic acid neurotoxicity.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Caudate Nucleus; Cell Count; Cerebral Cortex; | 2004 |
Deleterious effects of minocycline in animal models of Parkinson's disease and Huntington's disease.
Topics: Animals; Cells, Cultured; Convulsants; Corpus Striatum; Disease Models, Animal; Female; Huntington D | 2004 |
Mice lacking alpha-synuclein are resistant to mitochondrial toxins.
Topics: alpha-Synuclein; Animals; Malonates; Mice; Mice, Mutant Strains; Mitochondria; Neurons; Neurotoxins; | 2006 |
Neuronal ectopic expression of tyrosine hydroxylase in the mouse striatum by combined administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and 3-nitropropionic acid.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Aromatic-L-Amino-Acid Decarboxylases; Convuls | 2001 |
A simple method to measure stride length as an index of nigrostriatal dysfunction in mice.
Topics: Animals; Antipsychotic Agents; Benserazide; Convulsants; Corpus Striatum; Dopamine Agents; Dopamine | 2002 |