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3-nitropropionic acid and Inflammation

3-nitropropionic acid has been researched along with Inflammation in 9 studies

3-nitropropionic acid: succinate dehydrogenase inactivator; biosynthesized by FABACEAE plants from ASPARAGINE
3-nitropropanoic acid : A C-nitro compound that is propanoic acid in which one of the methyl hydrogens has been replaced by a nitro group.

Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.

Research Excerpts

ExcerptRelevanceReference
" The toxin 3-Nitropropionic acid (3-NP) can induce neuropathologies in the mice striatum and nigra substance, including excitotoxicity, neuroinflammation, and extensive neuronal atrophy, characterized by progressive motor dysfunction, dystonia, and memory loss, mimicking those observed in humans."8.02Combined treatment with C16 peptide and angiopoietin-1 confers neuroprotection and reduces inflammation in 3-nitropropionic acid-induced dystonia mice. ( Cai, HY; Fu, XX; Han, S; Jiang, H, 2021)
"Resveratrol is a naturally occurring stilbene which has shown promising results as treatment for several neurodegenerative diseases."7.88Alkylated resveratrol prodrugs and metabolites as potential therapeutics for neurodegenerative diseases. ( Adán, N; Belmonte-Reche, E; Caro, M; Delgado, M; González-Rey, E; Mateos-Martín, ML; Morales, JC; Peñalver, P, 2018)
" The toxin 3-Nitropropionic acid (3-NP) can induce neuropathologies in the mice striatum and nigra substance, including excitotoxicity, neuroinflammation, and extensive neuronal atrophy, characterized by progressive motor dysfunction, dystonia, and memory loss, mimicking those observed in humans."4.02Combined treatment with C16 peptide and angiopoietin-1 confers neuroprotection and reduces inflammation in 3-nitropropionic acid-induced dystonia mice. ( Cai, HY; Fu, XX; Han, S; Jiang, H, 2021)
"Resveratrol is a naturally occurring stilbene which has shown promising results as treatment for several neurodegenerative diseases."3.88Alkylated resveratrol prodrugs and metabolites as potential therapeutics for neurodegenerative diseases. ( Adán, N; Belmonte-Reche, E; Caro, M; Delgado, M; González-Rey, E; Mateos-Martín, ML; Morales, JC; Peñalver, P, 2018)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (11.11)29.6817
2010's4 (44.44)24.3611
2020's4 (44.44)2.80

Authors

AuthorsStudies
Saunders, MJ1
Edwards, BS1
Zhu, J1
Sklar, LA1
Graves, SW1
Gendy, AM1
El-Sadek, HM1
Amin, MM1
Ahmed, KA1
El-Sayed, MK1
El-Haddad, AE1
Soubh, A1
Li, X1
Gao, F1
Zhu, W1
Jiang, C1
Xu, J1
Zhang, J1
Meng, L1
Lu, S1
Eskandari, N1
Boroujeni, ME1
Abdollahifar, MA1
Piryaei, A1
Khodagholi, F1
Mirbehbahani, SH1
Siroosi, S1
Moghaddam, MH1
Aliaghaei, A1
Sadeghi, Y1
Fu, XX1
Cai, HY1
Jiang, H1
Han, S1
Peñalver, P1
Belmonte-Reche, E1
Adán, N1
Caro, M1
Mateos-Martín, ML1
Delgado, M1
González-Rey, E1
Morales, JC1
Jang, M1
Lee, MJ1
Cho, IH1
Fujioka, M1
Okamoto, Y1
Shinden, S1
Okano, HJ1
Okano, H1
Ogawa, K1
Matsunaga, T1
Perez-De La Cruz, V1
Santamaria, A1

Reviews

1 review available for 3-nitropropionic acid and Inflammation

ArticleYear
Integrative hypothesis for Huntington's disease: a brief review of experimental evidence.
    Physiological research, 2007, Volume: 56, Issue:5

    Topics: Animals; Calcium; Cell Death; Disease Models, Animal; Energy Metabolism; Excitatory Amino Acids; Hum

2007

Other Studies

8 other studies available for 3-nitropropionic acid and Inflammation

ArticleYear
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
    Current protocols in cytometry, 2010, Volume: Chapter 13

    Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr

2010
Glycyrrhizin prevents 3-nitropropionic acid-induced neurotoxicity by downregulating HMGB1/TLR4/NF-κB p65 signaling, and attenuating oxidative stress, inflammation, and apoptosis in rats.
    Life sciences, 2023, Feb-01, Volume: 314

    Topics: Animals; Apoptosis; Body Weight; Glycyrrhizic Acid; HMGB1 Protein; Huntington Disease; Inflammation;

2023
Pristane promotes anaerobic glycolysis to facilitate proinflammatory activation of macrophages and development of arthritis.
    Experimental cell research, 2021, 01-01, Volume: 398, Issue:1

    Topics: Anaerobiosis; Animals; Arthritis, Experimental; Cells, Cultured; Deoxyglucose; Glycolysis; Inflammat

2021
Transplantation of human dental pulp stem cells compensates for striatal atrophy and modulates neuro-inflammation in 3-nitropropionic acid rat model of Huntington's disease.
    Neuroscience research, 2021, Volume: 170

    Topics: Animals; Atrophy; Dental Pulp; Disease Models, Animal; Humans; Huntington Disease; Inflammation; Nit

2021
Combined treatment with C16 peptide and angiopoietin-1 confers neuroprotection and reduces inflammation in 3-nitropropionic acid-induced dystonia mice.
    Aging, 2021, 07-29, Volume: 13, Issue:14

    Topics: Angiopoietin-1; Animals; Anti-Inflammatory Agents; Brain; Capillary Permeability; Central Nervous Sy

2021
Alkylated resveratrol prodrugs and metabolites as potential therapeutics for neurodegenerative diseases.
    European journal of medicinal chemistry, 2018, Feb-25, Volume: 146

    Topics: Alkylation; Animals; Cell Survival; Cytokines; Dose-Response Relationship, Drug; Humans; Inflammatio

2018
Ethyl pyruvate ameliorates 3-nitropropionic acid-induced striatal toxicity through anti-neuronal cell death and anti-inflammatory mechanisms.
    Brain, behavior, and immunity, 2014, Volume: 38

    Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Behavior, Animal; Corpus Striatum; Inflammation; Male;

2014
Pharmacological inhibition of cochlear mitochondrial respiratory chain induces secondary inflammation in the lateral wall: a potential therapeutic target for sensorineural hearing loss.
    PloS one, 2014, Volume: 9, Issue:3

    Topics: Animals; Chemokines; Cochlea; Electron Transport; Female; Gene Expression Profiling; Genome; Hearing

2014