3-nitropropionic acid has been researched along with Hypoxia in 12 studies
3-nitropropionic acid: succinate dehydrogenase inactivator; biosynthesized by FABACEAE plants from ASPARAGINE
3-nitropropanoic acid : A C-nitro compound that is propanoic acid in which one of the methyl hydrogens has been replaced by a nitro group.
Hypoxia: Sub-optimal OXYGEN levels in the ambient air of living organisms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "3-nitropropionic acid (3-NPA) neurotoxicity and long-term effects of perinatal hypoxia were evaluated in 18 adult rats." | 7.69 | The effects of perinatal hypoxia on the behavioral, neurochemical, and neurohistological toxicity of the metabolic inhibitor 3-nitropropionic acid. ( Ali, SF; Binienda, Z; Ferguson, SA; Frederick, DL; Paule, MG; Rountree, RL; Scallet, AC; Schmued, L; Slikker, W, 1995) |
| "The effects of hypoxia (O2-free), aglycemia (glucose-free), ischemia (O2- and glucose-free) and chemical anoxia (by 3-nitropropionic acid; 3-NPA) were evaluated on the synaptic transmission in vitro." | 3.72 | Differential depression of spinal synaptic transmission in vitro by different hypoxic insults. ( Das Gupta, S; Deshpande, SB; Jha, A, 2004) |
| "Population spike amplitude (PSA) and NADH were measured during hypoxic hypoxia and recovery in hippocampal slices from untreated control animals (C slices) and slices prepared from animals pretreated in vivo with a single intraperitoneal injection of 3-nitropropionate (3NP) (3NP slices) or acetylsalicylate (ASA) (ASA slices)." | 3.70 | Primary hypoxic tolerance and chemical preconditioning during estrus cycle in mice. ( Huber, R; Kasischke, K; Li, H; Riepe, MW; Timmler, M, 1999) |
| "3-nitropropionic acid (3-NPA) neurotoxicity and long-term effects of perinatal hypoxia were evaluated in 18 adult rats." | 3.69 | The effects of perinatal hypoxia on the behavioral, neurochemical, and neurohistological toxicity of the metabolic inhibitor 3-nitropropionic acid. ( Ali, SF; Binienda, Z; Ferguson, SA; Frederick, DL; Paule, MG; Rountree, RL; Scallet, AC; Schmued, L; Slikker, W, 1995) |
| " We found differences in the baseline mRNA expression of adenosine A3 receptors in C3H mice and neuronal NOS in B6 mice as well as a distinct regulation of adenosine A3 receptors and estrogen receptor beta (no changes in C3H and B6 compared to upregulation in CD-1) on treatment of animals with a low dosage of 3-nitropropionate (20mg/kg body weight, i." | 1.32 | Strain dependence of receptor regulation on chemical preconditioning in mice hippocampus. ( Riepe, MW; Verstege, E; von Arnim, CA, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (25.00) | 18.2507 |
| 2000's | 8 (66.67) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Crawford, CA | 1 |
| Akopian, G | 1 |
| Ring, J | 1 |
| Jakowec, MW | 1 |
| Petzinger, GM | 1 |
| Andersen, JK | 1 |
| Vittozzi-Wong, P | 1 |
| Wang, K | 1 |
| Farley, CM | 1 |
| Charntikov, S | 1 |
| Mitroi, D | 1 |
| Beal, MF | 1 |
| Chow, R | 1 |
| Walsh, JP | 1 |
| Paddenberg, R | 2 |
| Ishaq, B | 1 |
| Goldenberg, A | 2 |
| Faulhammer, P | 2 |
| Rose, F | 1 |
| Weissmann, N | 1 |
| Braun-Dullaeus, RC | 2 |
| Kummer, W | 2 |
| Hellweg, R | 1 |
| von Arnim, CA | 4 |
| Büchner, M | 1 |
| Huber, R | 3 |
| Riepe, MW | 7 |
| Verstege, E | 2 |
| Jha, A | 1 |
| Das Gupta, S | 1 |
| Deshpande, SB | 1 |
| Etrich, SM | 2 |
| Lohmann, P | 1 |
| Lange-Asschenfeldt, C | 1 |
| Binienda, Z | 1 |
| Frederick, DL | 1 |
| Ferguson, SA | 1 |
| Rountree, RL | 1 |
| Paule, MG | 1 |
| Schmued, L | 1 |
| Ali, SF | 1 |
| Slikker, W | 1 |
| Scallet, AC | 1 |
| Kasischke, K | 2 |
| Raupach, A | 1 |
| Li, H | 1 |
| Timmler, M | 2 |
12 other studies available for 3-nitropropionic acid and Hypoxia
| Article | Year |
|---|---|
Acute and long-term response of dopamine nigrostriatal synapses to a single, low-dose episode of 3-nitropropionic acid-mediated chemical hypoxia.
Topics: Animals; Corpus Striatum; Dopamine; Drug Administration Schedule; Hypoxia; Lipid Peroxidation; Male; | 2011 |
Essential role of complex II of the respiratory chain in hypoxia-induced ROS generation in the pulmonary vasculature.
Topics: Animals; Anti-Bacterial Agents; Antihypertensive Agents; Antimycin A; Chelating Agents; Electron Tra | 2003 |
Neuroprotection and neuronal dysfunction upon repetitive inhibition of oxidative phosphorylation.
Topics: Action Potentials; Amyloid beta-Protein Precursor; Animals; Cell Survival; Drug Administration Sched | 2003 |
Mitochondrial complex II is essential for hypoxia-induced ROS generation and vasoconstriction in the pulmonary vasculature.
Topics: Animals; Electron Transport Complex II; Hypoxia; In Vitro Techniques; Mice; Mitochondria; Nitro Comp | 2003 |
Strain dependence of receptor regulation on chemical preconditioning in mice hippocampus.
Topics: Amyloid beta-Protein Precursor; Animals; Biomarkers; Estrogen Receptor alpha; Estrogen Receptor beta | 2004 |
Differential depression of spinal synaptic transmission in vitro by different hypoxic insults.
Topics: Animals; Electrodes; Ganglia, Spinal; Glucose; Hypoxia; Ischemia; Nitro Compounds; Oxygen; Propionat | 2004 |
Mechanisms of hypoxic tolerance in presymptomatic APP23 transgenic mice.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Disease Models, Animal; Gene Expression | 2006 |
The stamp of ancestry: roots of behavioral and neuronal impairment in adulthood.
Topics: Age Factors; Animals; Animals, Newborn; Female; Hypoxia; Learning; Long-Term Potentiation; Male; Mic | 2006 |
The effects of perinatal hypoxia on the behavioral, neurochemical, and neurohistological toxicity of the metabolic inhibitor 3-nitropropionic acid.
Topics: Animals; Behavior, Animal; Brain; Brain Chemistry; Dose-Response Relationship, Drug; Energy Metaboli | 1995 |
Acetylsalicylic acid increases tolerance against hypoxic and chemical hypoxia.
Topics: Action Potentials; Adaptation, Physiological; Adenosine Triphosphate; Animals; Aspirin; Extracellula | 1997 |
Primary hypoxic tolerance and chemical preconditioning during estrus cycle in mice.
Topics: Action Potentials; Adaptation, Physiological; Animals; Aspirin; Dose-Response Relationship, Drug; Es | 1999 |
Gender-dependent hypoxic tolerance mediated via gender-specific mechanisms.
Topics: Adaptation, Physiological; Animals; Convulsants; Estrogen Receptor alpha; Estrous Cycle; Female; Hip | 2002 |