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3-nitropropionic acid and Hypoglycemia

3-nitropropionic acid has been researched along with Hypoglycemia in 4 studies

3-nitropropionic acid: succinate dehydrogenase inactivator; biosynthesized by FABACEAE plants from ASPARAGINE
3-nitropropanoic acid : A C-nitro compound that is propanoic acid in which one of the methyl hydrogens has been replaced by a nitro group.

Hypoglycemia: A syndrome of abnormally low BLOOD GLUCOSE level. Clinical hypoglycemia has diverse etiologies. Severe hypoglycemia eventually lead to glucose deprivation of the CENTRAL NERVOUS SYSTEM resulting in HUNGER; SWEATING; PARESTHESIA; impaired mental function; SEIZURES; COMA; and even DEATH.

Research Excerpts

ExcerptRelevanceReference
" We tested the ability of Bcl-xl overexpression to protect primary cultures of embryonic rat septal neurons subjected to one of four different stresses: 6 h of combined oxygen-glucose deprivation, which produces rapid cell death, or a 24 h exposure to hypoglycemia, hyperglycemia, or 1mM 3-nitropropionic acid (an inhibitor of mitochondrial respiration), which results in a more slowly-developing death."3.73Overexpression of Bcl-xl protects septal neurons from prolonged hypoglycemia and from acute ischemia-like stress. ( Barrett, JN; Nonner, D; Panickar, KS, 2005)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (75.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Panickar, KS1
Nonner, D1
Barrett, JN1
Ho, DY1
Saydam, TC1
Fink, SL1
Lawrence, MS1
Sapolsky, RM1
Boireau, A1
Meunier, M1
Doble, A1
Allen, JW1
Knoblach, SM1
Faden, AI1

Other Studies

4 other studies available for 3-nitropropionic acid and Hypoglycemia

ArticleYear
Overexpression of Bcl-xl protects septal neurons from prolonged hypoglycemia and from acute ischemia-like stress.
    Neuroscience, 2005, Volume: 135, Issue:1

    Topics: Adenosine Triphosphate; Animals; Antimetabolites; bcl-X Protein; Brain Ischemia; Caspase 3; Caspases

2005
Defective herpes simplex virus vectors expressing the rat brain glucose transporter protect cultured neurons from necrotic insults.
    Journal of neurochemistry, 1995, Volume: 65, Issue:2

    Topics: Animals; Brain; Chlorocebus aethiops; Defective Viruses; Gene Expression; Genetic Vectors; Glutamic

1995
3-Nitropropionic acid exacerbates [3H]GABA release evoked by glucose deprivation in rat striatal slices.
    The Journal of pharmacy and pharmacology, 1996, Volume: 48, Issue:1

    Topics: Animals; Corpus Striatum; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Ac

1996
Combined mechanical trauma and metabolic impairment in vitro induces NMDA receptor-dependent neuronal cell death and caspase-3-dependent apoptosis.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1999, Volume: 13, Issue:13

    Topics: Animals; Apoptosis; Brain Injuries; Caspase 3; Caspase Inhibitors; Caspases; Cell Death; Cells, Cult

1999