3-nitropropionic acid has been researched along with Encephalopathy, Toxic in 36 studies
3-nitropropionic acid: succinate dehydrogenase inactivator; biosynthesized by FABACEAE plants from ASPARAGINE
3-nitropropanoic acid : A C-nitro compound that is propanoic acid in which one of the methyl hydrogens has been replaced by a nitro group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Since carvedilol and melatonin act as free-radical scavengers, this study examined the effect of carvedilol (10(-5) M) and melatonin (10(-5) M) on oxidative and cell damage induced by 3NP in N1E-115 neuroblastoma cells." | 7.75 | Neuroprotective effect of carvedilol and melatonin on 3-nitropropionic acid-induced neurotoxicity in neuroblastoma. ( Collado, JA; Espínola, C; Feijóo, M; Gómez, MM; Medina, FJ; Montilla, P; Moreno, E; Muñoz, C; Muntané, J; Ruiz, C; Tasset, I; Túnez, I, 2009) |
| " Since carvedilol and melatonin act as free-radical scavengers, this study examined the effect of carvedilol (10(-5) M) and melatonin (10(-5) M) on oxidative and cell damage induced by 3NP in N1E-115 neuroblastoma cells." | 3.75 | Neuroprotective effect of carvedilol and melatonin on 3-nitropropionic acid-induced neurotoxicity in neuroblastoma. ( Collado, JA; Espínola, C; Feijóo, M; Gómez, MM; Medina, FJ; Montilla, P; Moreno, E; Muñoz, C; Muntané, J; Ruiz, C; Tasset, I; Túnez, I, 2009) |
| " However, their toxic properties have yet to be explored in the nematode Caenorhabditis elegans (C." | 1.48 | Comparison of the Toxic Effects of Quinolinic Acid and 3-Nitropropionic Acid in C. elegans: Involvement of the SKN-1 Pathway. ( Aguilera-González, MF; Aschner, M; Avila, DS; Colonnello, A; de Lima, ME; García-Contreras, R; Kotlar, I; Ortíz-Plata, A; Santamaría, A; Soares, FAA, 2018) |
| "Naringin treatment enhances the antioxidant defense by increasing the activities of enzymatic antioxidants and the level of reduced glutathione." | 1.42 | Neuroprotective efficacy of naringin on 3-nitropropionic acid-induced mitochondrial dysfunction through the modulation of Nrf2 signaling pathway in PC12 cells. ( Ganapasam, S; Kulasekaran, G, 2015) |
| "Huntington's disease is an autosomal dominant, progressive, and fatal neurodegenerative disease characterized by motor and non-motor symptoms." | 1.40 | Role of neurosteroids in experimental 3-nitropropionic acid induced neurotoxicity in rats. ( Deshmukh, R; Khan, A; Kumar, P; Lal Sharma, P, 2014) |
| "Pretreatment with hesperidin (100 mg/kg) ahead of 3-NP prevented any changes of locomotor activity or PPI response, slightly increased cortical, striatal and hippocampal MDA levels by 10% and reduced respective catalase activity by 22%, 20% and 5%." | 1.38 | Potential neuroprotective effects of hesperidin on 3-nitropropionic acid-induced neurotoxicity in rats. ( Abdel-Tawab, AM; Khalifa, AE; Menze, ET; Tadros, MG, 2012) |
| " The subacutely treated rats were dissected and organ weights measured to study general toxic effects." | 1.33 | Effects of 3-nitropropionic acid in rats: general toxicity and functional neurotoxicity. ( Nagymajtényi, L; Papp, A; Szabó, A, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 12 (33.33) | 29.6817 |
| 2010's | 20 (55.56) | 24.3611 |
| 2020's | 4 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Habib, MZ | 1 |
| Tadros, MG | 3 |
| Abd-Alkhalek, HA | 1 |
| Mohamad, MI | 1 |
| Eid, DM | 1 |
| Hassan, FE | 1 |
| Elhelaly, H | 1 |
| Faramawy, YE | 1 |
| Aboul-Fotouh, S | 1 |
| Kadir, A | 1 |
| Singh, J | 1 |
| Rahi, V | 4 |
| Kumar, P | 11 |
| Ram, P | 3 |
| Mohammed, RA | 1 |
| Mansour, SM | 1 |
| Kotlar, I | 1 |
| Colonnello, A | 1 |
| Aguilera-González, MF | 1 |
| Avila, DS | 1 |
| de Lima, ME | 1 |
| García-Contreras, R | 1 |
| Ortíz-Plata, A | 1 |
| Soares, FAA | 1 |
| Aschner, M | 1 |
| Santamaría, A | 3 |
| Danduga, RCSR | 1 |
| Dondapati, SR | 1 |
| Kola, PK | 1 |
| Grace, L | 1 |
| Tadigiri, RVB | 1 |
| Kanakaraju, VK | 1 |
| Liu, P | 1 |
| Li, Y | 1 |
| Liu, D | 1 |
| Ji, X | 1 |
| Chi, T | 1 |
| Li, L | 1 |
| Zou, L | 1 |
| Petkau, TL | 1 |
| Zhu, S | 1 |
| Lu, G | 1 |
| Fernando, S | 1 |
| Cynader, M | 1 |
| Leavitt, BR | 1 |
| Thangarajan, S | 1 |
| Deivasigamani, A | 1 |
| Natarajan, SS | 1 |
| Krishnan, P | 1 |
| Mohanan, SK | 1 |
| Khan, A | 2 |
| Deshmukh, R | 1 |
| Lal Sharma, P | 1 |
| Mahdy, HM | 1 |
| Mohamed, MR | 1 |
| Emam, MA | 1 |
| Karim, AM | 1 |
| Abdel-Naim, AB | 1 |
| Abdel-Naim, A | 1 |
| Khalifa, AE | 3 |
| K M, DJ | 1 |
| Al-Sabahi, BN | 1 |
| Fatope, MO | 1 |
| Essa, MM | 1 |
| Subash, S | 1 |
| Al-Busafi, SN | 1 |
| Al-Kusaibi, FS | 1 |
| Manivasagam, T | 1 |
| Jamwal, S | 1 |
| Bijjem, KR | 1 |
| Prakash, A | 2 |
| Hanna, DM | 1 |
| Malik, J | 1 |
| Choudhary, S | 1 |
| Kaur, M | 1 |
| Kalia, AN | 1 |
| Kulasekaran, G | 1 |
| Ganapasam, S | 1 |
| Calderón Guzmán, D | 1 |
| Brizuela, NO | 1 |
| Ortíz Herrera, M | 1 |
| Hernández García, E | 1 |
| Barragán Mejía, G | 1 |
| Juárez Olguín, H | 1 |
| Valenzuela Peraza, A | 1 |
| Attilus, J | 1 |
| Labra Ruíz, N | 1 |
| Maya-López, M | 1 |
| Ruiz-Contreras, HA | 1 |
| de Jesús Negrete-Ruíz, M | 1 |
| Martínez-Sánchez, JE | 1 |
| Benítez-Valenzuela, J | 1 |
| Colín-González, AL | 1 |
| Villeda-Hernández, J | 1 |
| Sánchez-Chapul, L | 1 |
| Parra-Cid, C | 1 |
| Rangel-López, E | 1 |
| He, Y | 1 |
| Akumuo, RC | 1 |
| Yang, Y | 1 |
| Hewett, SJ | 1 |
| Garcia, E | 1 |
| Limon, D | 1 |
| Perez-De La Cruz, V | 1 |
| Giordano, M | 1 |
| Diaz-Muñoz, M | 1 |
| Maldonado, PD | 1 |
| Herrera-Mundo, MN | 1 |
| Pedraza-Chaverri, J | 1 |
| Kumar, A | 3 |
| Kalonia, H | 1 |
| Puerta, E | 1 |
| Hervias, I | 1 |
| Barros-Miñones, L | 1 |
| Jordan, J | 1 |
| Ricobaraza, A | 1 |
| Cuadrado-Tejedor, M | 1 |
| García-Osta, A | 1 |
| Aguirre, N | 1 |
| Tasset, I | 1 |
| Espínola, C | 1 |
| Medina, FJ | 1 |
| Feijóo, M | 1 |
| Ruiz, C | 1 |
| Moreno, E | 1 |
| Gómez, MM | 1 |
| Collado, JA | 1 |
| Muñoz, C | 1 |
| Muntané, J | 1 |
| Montilla, P | 1 |
| Túnez, I | 1 |
| Dastidar, SG | 1 |
| Bardai, FH | 1 |
| Ma, C | 1 |
| Price, V | 1 |
| Rawat, V | 1 |
| Verma, P | 1 |
| Narayanan, V | 1 |
| D'Mello, SR | 1 |
| Menze, ET | 1 |
| Abdel-Tawab, AM | 1 |
| Brownell, AL | 1 |
| Chen, YI | 1 |
| Yu, M | 1 |
| Wang, X | 1 |
| Dedeoglu, A | 1 |
| Cicchetti, F | 1 |
| Jenkins, BG | 1 |
| Beal, MF | 1 |
| Szabó, A | 1 |
| Papp, A | 1 |
| Nagymajtényi, L | 1 |
| Ueda, S | 1 |
| Sato, N | 1 |
| Misu, T | 1 |
| Binienda, ZK | 2 |
| Ali, SF | 2 |
| Virmani, A | 2 |
| Amato, A | 2 |
| Salem, N | 2 |
| Przybyla, BD | 2 |
| Robinson, BL | 1 |
| Padi, SS | 1 |
| Naidu, PS | 1 |
| Ahuja, M | 1 |
| Bishnoi, M | 1 |
| Chopra, K | 1 |
| Pubill, D | 1 |
| Verdaguer, E | 1 |
| Canudas, AM | 1 |
| Sureda, FX | 1 |
| Escubedo, E | 1 |
| Camarasa, J | 1 |
| Pallàs, M | 1 |
| Camins, A | 1 |
1 review available for 3-nitropropionic acid and Encephalopathy, Toxic
| Article | Year |
|---|---|
[Aristolochic acid nephropathy and acute encephalopathy related to Pleurocybella porrigens (Sugihiratake)].
Topics: Acute Disease; Acute Kidney Injury; Agaricales; Animals; Aristolochic Acids; Drugs, Chinese Herbal; | 2006 |
35 other studies available for 3-nitropropionic acid and Encephalopathy, Toxic
| Article | Year |
|---|---|
Harmine prevents 3-nitropropionic acid-induced neurotoxicity in rats via enhancing NRF2-mediated signaling: Involvement of p21 and AMPK.
Topics: Adenylate Kinase; AMP-Activated Protein Kinases; Animals; Cyclin-Dependent Kinase Inhibitor p21; Har | 2022 |
Berberine Ameliorate Haloperidol and 3-Nitropropionic Acid-Induced Neurotoxicity in Rats.
Topics: Animals; Antioxidants; Berberine; Catalase; Haloperidol; Huntington Disease; Motor Activity; Neuropr | 2022 |
Filgrastim, a Recombinant Form of Granulocyte Colony-stimulating Factor, Ameliorates 3-nitropropionic Acid and Haloperidol-induced Striatal Neurotoxicity in Rats.
Topics: Animals; Filgrastim; Granulocyte Colony-Stimulating Factor; Haloperidol; Huntington Disease; Movemen | 2022 |
Filgrastim, a Recombinant Form of Granulocyte Colony-stimulating Factor, Ameliorates 3-nitropropionic Acid and Haloperidol-induced Striatal Neurotoxicity in Rats.
Topics: Animals; Filgrastim; Granulocyte Colony-Stimulating Factor; Haloperidol; Huntington Disease; Movemen | 2022 |
Filgrastim, a Recombinant Form of Granulocyte Colony-stimulating Factor, Ameliorates 3-nitropropionic Acid and Haloperidol-induced Striatal Neurotoxicity in Rats.
Topics: Animals; Filgrastim; Granulocyte Colony-Stimulating Factor; Haloperidol; Huntington Disease; Movemen | 2022 |
Filgrastim, a Recombinant Form of Granulocyte Colony-stimulating Factor, Ameliorates 3-nitropropionic Acid and Haloperidol-induced Striatal Neurotoxicity in Rats.
Topics: Animals; Filgrastim; Granulocyte Colony-Stimulating Factor; Haloperidol; Huntington Disease; Movemen | 2022 |
Filgrastim, a Recombinant Form of Granulocyte Colony-stimulating Factor, Ameliorates 3-nitropropionic Acid and Haloperidol-induced Striatal Neurotoxicity in Rats.
Topics: Animals; Filgrastim; Granulocyte Colony-Stimulating Factor; Haloperidol; Huntington Disease; Movemen | 2022 |
Filgrastim, a Recombinant Form of Granulocyte Colony-stimulating Factor, Ameliorates 3-nitropropionic Acid and Haloperidol-induced Striatal Neurotoxicity in Rats.
Topics: Animals; Filgrastim; Granulocyte Colony-Stimulating Factor; Haloperidol; Huntington Disease; Movemen | 2022 |
Filgrastim, a Recombinant Form of Granulocyte Colony-stimulating Factor, Ameliorates 3-nitropropionic Acid and Haloperidol-induced Striatal Neurotoxicity in Rats.
Topics: Animals; Filgrastim; Granulocyte Colony-Stimulating Factor; Haloperidol; Huntington Disease; Movemen | 2022 |
Filgrastim, a Recombinant Form of Granulocyte Colony-stimulating Factor, Ameliorates 3-nitropropionic Acid and Haloperidol-induced Striatal Neurotoxicity in Rats.
Topics: Animals; Filgrastim; Granulocyte Colony-Stimulating Factor; Haloperidol; Huntington Disease; Movemen | 2022 |
Filgrastim, a Recombinant Form of Granulocyte Colony-stimulating Factor, Ameliorates 3-nitropropionic Acid and Haloperidol-induced Striatal Neurotoxicity in Rats.
Topics: Animals; Filgrastim; Granulocyte Colony-Stimulating Factor; Haloperidol; Huntington Disease; Movemen | 2022 |
Sodium hydrogen sulfide upregulates cystathionine β-synthase and protects striatum against 3-nitropropionic acid-induced neurotoxicity in rats.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Cognitive Dysfunction; Cystathionine bet | 2021 |
Comparison of the Toxic Effects of Quinolinic Acid and 3-Nitropropionic Acid in C. elegans: Involvement of the SKN-1 Pathway.
Topics: Animals; Antihypertensive Agents; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Corpus St | 2018 |
Neuroprotective activity of tetramethylpyrazine against 3-nitropropionic acid induced Huntington's disease-like symptoms in rats.
Topics: Animals; Behavior, Animal; Catalase; Corpus Striatum; Glutathione; Hippocampus; Huntington Disease; | 2018 |
Tolfenamic Acid Attenuates 3-Nitropropionic Acid-Induced Biochemical Alteration in Mice.
Topics: Animals; Antioxidants; Cytokines; Lipid Peroxidation; Male; Mice; Motor Activity; Neuroprotective Ag | 2018 |
Sensitivity to neurotoxic stress is not increased in progranulin-deficient mice.
Topics: Animals; Fluoresceins; Granulins; Intercellular Signaling Peptides and Proteins; Kainic Acid; Mice; | 2013 |
Neuroprotective activity of L-theanine on 3-nitropropionic acid-induced neurotoxicity in rat striatum.
Topics: Animals; Body Weight; Brain; Catalase; Convulsants; Corpus Striatum; Exploratory Behavior; Glutamate | 2014 |
Role of neurosteroids in experimental 3-nitropropionic acid induced neurotoxicity in rats.
Topics: Animals; Behavior, Animal; Brain; Catalase; Glutathione; Huntington Disease; Interleukin-1beta; Lipi | 2014 |
The anti-apoptotic and anti-inflammatory properties of puerarin attenuate 3-nitropropionic-acid induced neurotoxicity in rats.
Topics: Adenosine Triphosphate; Animals; Anti-Inflammatory Agents; Apoptosis; Brain; Isoflavones; Male; Neur | 2014 |
Neuroprotective efficacy of a combination of fish oil and ferulic acid against 3-nitropropionic acid-induced oxidative stress and neurotoxicity in rats: behavioural and biochemical evidence.
Topics: Animals; Antioxidants; Behavior, Animal; Coumaric Acids; Energy Metabolism; Fish Oils; Male; Neuropr | 2014 |
Pomegranate seed oil: Effect on 3-nitropropionic acid-induced neurotoxicity in PC12 cells and elucidation of unsaturated fatty acids composition.
Topics: Animals; Antioxidants; Cell Line, Tumor; Cell Survival; Dietary Supplements; Ethnopharmacology; Lino | 2017 |
Neuroprotective effect of hemeoxygenase-1/glycogen synthase kinase-3β modulators in 3-nitropropionic acid-induced neurotoxicity in rats.
Topics: Animals; Body Weight; Corpus Striatum; Encephalitis; Glycogen Synthase Kinase 3; Glycogen Synthase K | 2015 |
ADIOL protects against 3-NP-induced neurotoxicity in rats: Possible impact of its anti-oxidant, anti-inflammatory and anti-apoptotic actions.
Topics: Analysis of Variance; Androstenedione; Animals; Antioxidants; Apoptosis; Body Weight; Caspase 3; Cat | 2015 |
Protective effect of Convolvulus pluricaulis standardized extract and its fractions against 3-nitropropionic acid-induced neurotoxicity in rats.
Topics: Animals; Convolvulus; Male; Motor Activity; Neuroprotective Agents; Neurotoxicity Syndromes; Nitro C | 2015 |
Neuroprotective potential of antioxidant potent fractions from Convolvulus pluricaulis Chois. in 3-nitropropionic acid challenged rats.
Topics: Animals; Antioxidants; Behavior, Animal; Body Weight; Convolvulus; Corpus Striatum; Glutathione; Hun | 2016 |
Neuroprotective efficacy of naringin on 3-nitropropionic acid-induced mitochondrial dysfunction through the modulation of Nrf2 signaling pathway in PC12 cells.
Topics: Animals; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Cell Line, Tumor; Cell Survival; Elect | 2015 |
Effect of cerebrolysin on dopaminergic neurodegeneration of rat with oxidative stress induced by 3-nitropropionic acid.
Topics: Amino Acids; Animals; Antioxidants; Calcium; Cerebellar Cortex; Cerebellum; Cerebrum; Convulsants; D | 2016 |
URB597 reduces biochemical, behavioral and morphological alterations in two neurotoxic models in rats.
Topics: Amidohydrolases; Animals; Apomorphine; Behavior, Animal; Benzamides; Body Weight; Carbamates; Inject | 2017 |
Mice deficient in L-12/15 lipoxygenase show increased vulnerability to 3-nitropropionic acid neurotoxicity.
Topics: Animals; Arachidonate 12-Lipoxygenase; Arachidonate 15-Lipoxygenase; Corpus Striatum; Disease Models | 2017 |
Lipid peroxidation, mitochondrial dysfunction and neurochemical and behavioural deficits in different neurotoxic models: protective role of S-allylcysteine.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antioxidants; Basal Ganglia; Behavior, Animal | 2008 |
Protective effects of epigallocatechin gallate following 3-nitropropionic acid-induced brain damage: possible nitric oxide mechanisms.
Topics: Animals; Antioxidants; Behavior, Animal; Catechin; Disease Models, Animal; Dose-Response Relationshi | 2009 |
Lycopene modulates nitric oxide pathways against 3-nitropropionic acid-induced neurotoxicity.
Topics: Animals; Anticarcinogenic Agents; Body Weight; Carotenoids; Catalase; Coloring Agents; Electron Tran | 2009 |
Sildenafil protects against 3-nitropropionic acid neurotoxicity through the modulation of calpain, CREB, and BDNF.
Topics: Analysis of Variance; Animals; Blotting, Western; Brain-Derived Neurotrophic Factor; Calpain; Corpus | 2010 |
Neuroprotective effect of carvedilol and melatonin on 3-nitropropionic acid-induced neurotoxicity in neuroblastoma.
Topics: Animals; Carbazoles; Carvedilol; Free Radical Scavengers; Glutathione; L-Lactate Dehydrogenase; Lipi | 2009 |
Isoform-specific toxicity of Mecp2 in postmitotic neurons: suppression of neurotoxicity by FoxG1.
Topics: Animals; Animals, Newborn; Apoptosis; Cells, Cultured; Cerebellum; Disease Models, Animal; Female; F | 2012 |
Potential neuroprotective effects of hesperidin on 3-nitropropionic acid-induced neurotoxicity in rats.
Topics: Acoustic Stimulation; Analysis of Variance; Animals; Brain; Catalase; Convulsants; Disease Models, A | 2012 |
3-Nitropropionic acid-induced neurotoxicity--assessed by ultra high resolution positron emission tomography with comparison to magnetic resonance spectroscopy.
Topics: Acute Disease; Animals; Behavior, Animal; Body Weight; Brain; Choline; Chronic Disease; Disease Mode | 2004 |
Effects of 3-nitropropionic acid in rats: general toxicity and functional neurotoxicity.
Topics: Animals; Evoked Potentials; Male; Neurotoxicity Syndromes; Nitro Compounds; Organ Size; Propionates; | 2005 |
Co-regulation of dopamine D1 receptor and uncoupling protein-2 expression in 3-nitropropionic acid-induced neurotoxicity: neuroprotective role of L-carnitine.
Topics: Animals; Body Temperature; Carnitine; Disease Models, Animal; Drug Interactions; Gene Expression Reg | 2006 |
Effects of L-carnitine pretreatment in methamphetamine and 3-nitropropionic acid-induced neurotoxicity.
Topics: Animals; Antihypertensive Agents; Carnitine; Dopamine Agents; Male; Methamphetamine; Neurotoxicity S | 2006 |
Cyclooxygenase inhibition attenuates 3-nitropropionic acid-induced neurotoxicity in rats: possible antioxidant mechanisms.
Topics: Animals; Behavior, Animal; Brain; Cyclooxygenase Inhibitors; Glutathione; Isoxazoles; Lipid Peroxida | 2007 |
Protective effect of minocycline, a semi-synthetic second-generation tetracycline against 3-nitropropionic acid (3-NP)-induced neurotoxicity.
Topics: Animals; Anti-Bacterial Agents; Behavior, Animal; Body Weight; Brain Chemistry; Enzyme Inhibitors; E | 2008 |
Orphenadrine prevents 3-nitropropionic acid-induced neurotoxicity in vitro and in vivo.
Topics: Animals; Antihypertensive Agents; Blotting, Western; Body Weight; Cell Survival; Cerebellum; Corpus | 2001 |