3-nitropropionic acid has been researched along with Dyskinesia, Medication-Induced in 11 studies
3-nitropropionic acid: succinate dehydrogenase inactivator; biosynthesized by FABACEAE plants from ASPARAGINE
3-nitropropanoic acid : A C-nitro compound that is propanoic acid in which one of the methyl hydrogens has been replaced by a nitro group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Quinolinic acid (QUIN) was used as a typical excitotoxic/pro-oxidant inducer, 3-nitropropionic acid (3-NP) was employed as a mitochondrial function inhibitor, and their combination (QUIN + 3-NP) was also evaluated in in vitro studies." | 1.36 | Antioxidant strategy to rescue synaptosomes from oxidative damage and energy failure in neurotoxic models in rats: protective role of S-allylcysteine. ( Elinos-Calderón, D; Galván-Arzate, S; Maldonado, PD; Pedraza-Chaverrí, J; Pérez-De La Cruz, V; Robledo-Arratia, Y; Santamaría, A, 2010) |
| " In astrocyte cultures, the toxic effects of 3-NPA were associated with corresponding increases in the NO(2)(-) level, and this toxicity was attenuated by hemoglobin (Hb; 20 microM), which quenches NO." | 1.33 | Involvement of nitric oxide in 3-nitropropionic acid-induced striatal toxicity in rats. ( Baba, H; Deshpande, SB; Hida, H; Masuda, T; Nishino, H; Takei-Io, N, 2006) |
| "The effects of a previous long-term administration of the mitochondrial toxin 3-nitropropionic acid were studied on an animal model of tardive dyskinesia, i." | 1.31 | The mitochondrial toxin 3-nitropropionic acid aggravates reserpine-induced oral dyskinesia in rats. ( Abilio, VC; Araujo, CC; Bergamo, M; Calvente, PR; D'Almeida, V; Frussa, FR; Ribeiro, Rde A, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 8 (72.73) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rosenstock, TR | 1 |
| Abílio, VC | 2 |
| Frussa-Filho, R | 1 |
| Kiyomoto, BH | 1 |
| Smaili, SS | 1 |
| Pelegrí, C | 1 |
| Duran-Vilaregut, J | 1 |
| del Valle, J | 1 |
| Crespo-Biel, N | 1 |
| Ferrer, I | 1 |
| Pallàs, M | 1 |
| Camins, A | 1 |
| Vilaplana, J | 1 |
| Elinos-Calderón, D | 1 |
| Robledo-Arratia, Y | 1 |
| Pérez-De La Cruz, V | 1 |
| Maldonado, PD | 1 |
| Galván-Arzate, S | 1 |
| Pedraza-Chaverrí, J | 1 |
| Santamaría, A | 1 |
| Túnez, I | 1 |
| Collado, JA | 1 |
| Medina, FJ | 1 |
| Peña, J | 1 |
| Del C Muñoz, M | 1 |
| Jimena, I | 1 |
| Franco, F | 1 |
| Rueda, I | 1 |
| Feijóo, M | 1 |
| Muntané, J | 1 |
| Montilla, P | 1 |
| Deshpande, SB | 1 |
| Hida, H | 1 |
| Takei-Io, N | 1 |
| Masuda, T | 1 |
| Baba, H | 1 |
| Nishino, H | 1 |
| Andreassen, OA | 2 |
| Jørgensen, HA | 2 |
| Ferrante, RJ | 1 |
| Beal, MF | 1 |
| Dautry, C | 1 |
| Vaufrey, F | 1 |
| Brouillet, E | 2 |
| Bizat, N | 2 |
| Henry, PG | 1 |
| Condé, F | 2 |
| Bloch, G | 1 |
| Hantraye, P | 2 |
| Ouary, S | 1 |
| Altairac, S | 1 |
| Ménétrat, H | 1 |
| Mittoux, V | 1 |
| Calvente, PR | 1 |
| Araujo, CC | 1 |
| Bergamo, M | 1 |
| D'Almeida, V | 1 |
| Ribeiro, Rde A | 1 |
| Frussa, FR | 1 |
| Lastres-Becker, I | 1 |
| Hansen, HH | 1 |
| Berrendero, F | 1 |
| De Miguel, R | 1 |
| Pérez-Rosado, A | 1 |
| Manzanares, J | 1 |
| Ramos, JA | 1 |
| Fernández-Ruiz, J | 1 |
11 other studies available for 3-nitropropionic acid and Dyskinesia, Medication-Induced
| Article | Year |
|---|---|
Old mice present increased levels of succinate dehydrogenase activity and lower vulnerability to dyskinetic effects of 3-nitropropionic acid.
Topics: Aging; Animals; Brain; Dyskinesia, Drug-Induced; Immunohistochemistry; Male; Mice; Mice, Inbred CBA; | 2009 |
Cell cycle activation in striatal neurons from Huntington's disease patients and rats treated with 3-nitropropionic acid.
Topics: Animals; Apoptosis; Cell Cycle Proteins; Convulsants; Corpus Striatum; Cyclin D1; Disease Models, An | 2008 |
Antioxidant strategy to rescue synaptosomes from oxidative damage and energy failure in neurotoxic models in rats: protective role of S-allylcysteine.
Topics: Animals; Antioxidants; Brain; Corpus Striatum; Cysteine; Disease Models, Animal; Dyskinesia, Drug-In | 2010 |
17 beta-Estradiol may affect vulnerability of striatum in a 3-nitropropionic acid-induced experimental model of Huntington's disease in ovariectomized rats.
Topics: Animals; Apoptosis; Caspase 3; Caspases; Cell Survival; Convulsants; Corpus Striatum; Cytoprotection | 2006 |
Involvement of nitric oxide in 3-nitropropionic acid-induced striatal toxicity in rats.
Topics: Animals; Astrocytes; Cells, Cultured; Convulsants; Corpus Striatum; Disease Models, Animal; Dose-Res | 2006 |
The mitochondrial toxin 3-nitropropionic acid induces vacuous chewing movements in rats. Implications for tardive dyskinesia?
Topics: Animals; Behavior, Animal; Dyskinesia, Drug-Induced; Female; Mastication; Mitochondria; Movement; Ne | 1995 |
Oral Dyskinesias and striatal lesions in rats after long-term co-treatment with haloperidol and 3-nitropropionic acid.
Topics: Analysis of Variance; Animals; Anti-Dyskinesia Agents; Antihypertensive Agents; Behavior, Animal; Co | 1998 |
Early N-acetylaspartate depletion is a marker of neuronal dysfunction in rats and primates chronically treated with the mitochondrial toxin 3-nitropropionic acid.
Topics: Animals; Aspartic Acid; Biomarkers; Cerebral Cortex; Corpus Striatum; Dyskinesia, Drug-Induced; In S | 2000 |
Major strain differences in response to chronic systemic administration of the mitochondrial toxin 3-nitropropionic acid in rats: implications for neuroprotection studies.
Topics: Animals; Behavior, Animal; Cell Survival; Convulsants; Disease Models, Animal; Drug Administration R | 2000 |
The mitochondrial toxin 3-nitropropionic acid aggravates reserpine-induced oral dyskinesia in rats.
Topics: Adrenergic Uptake Inhibitors; Animals; Convulsants; Disease Models, Animal; Drug Synergism; Dyskines | 2002 |
Alleviation of motor hyperactivity and neurochemical deficits by endocannabinoid uptake inhibition in a rat model of Huntington's disease.
Topics: Animals; Arachidonic Acids; Cannabinoid Receptor Modulators; Cannabinoids; Convulsants; Disease Mode | 2002 |