3-nitropropionic acid has been researched along with Disease Exacerbation in 7 studies
3-nitropropionic acid: succinate dehydrogenase inactivator; biosynthesized by FABACEAE plants from ASPARAGINE
3-nitropropanoic acid : A C-nitro compound that is propanoic acid in which one of the methyl hydrogens has been replaced by a nitro group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Chronic administration of 3-nitropropionic acid (3-NP), a suicide inhibitor of succinate dehydrogenase, causes prolonged energy impairments and replicates most of the pathophysiological features of HD, including preferential striatal degeneration." | 1.31 | The mitochondrial toxin 3-nitropropionic acid induces striatal neurodegeneration via a c-Jun N-terminal kinase/c-Jun module. ( Besson, MJ; Brouillet, E; Caboche, J; Garcia, M; Pages, C; Vanhoutte, P, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (85.71) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mievis, S | 1 |
| Blum, D | 1 |
| Ledent, C | 1 |
| Fernagut, PO | 1 |
| Diguet, E | 1 |
| Bioulac, B | 1 |
| Tison, F | 1 |
| Brownell, AL | 1 |
| Chen, YI | 1 |
| Yu, M | 1 |
| Wang, X | 1 |
| Dedeoglu, A | 1 |
| Cicchetti, F | 1 |
| Jenkins, BG | 1 |
| Beal, MF | 1 |
| de Lago, E | 1 |
| Fernández-Ruiz, J | 1 |
| Ortega-Gutiérrez, S | 1 |
| Cabranes, A | 1 |
| Pryce, G | 1 |
| Baker, D | 1 |
| López-Rodríguez, M | 1 |
| Ramos, JA | 1 |
| Ramaswamy, S | 1 |
| McBride, JL | 1 |
| Kordower, JH | 1 |
| Garcia, M | 1 |
| Vanhoutte, P | 1 |
| Pages, C | 1 |
| Besson, MJ | 1 |
| Brouillet, E | 2 |
| Caboche, J | 1 |
| Mittoux, V | 1 |
| Ouary, S | 1 |
| Monville, C | 1 |
| Lisovoski, F | 1 |
| Poyot, T | 1 |
| Conde, F | 1 |
| Escartin, C | 1 |
| Robichon, R | 1 |
| Peschanski, M | 1 |
| Hantraye, P | 1 |
1 review available for 3-nitropropionic acid and Disease Exacerbation
| Article | Year |
|---|---|
Animal models of Huntington's disease.
Topics: Animals; Disease Models, Animal; Disease Progression; Genetic Vectors; Huntington Disease; Lentiviru | 2007 |
6 other studies available for 3-nitropropionic acid and Disease Exacerbation
| Article | Year |
|---|---|
Worsening of Huntington disease phenotype in CB1 receptor knockout mice.
Topics: Analysis of Variance; Animals; Corpus Striatum; Disease Models, Animal; Disease Progression; Female; | 2011 |
MPTP potentiates 3-nitropropionic acid-induced striatal damage in mice: reference to striatonigral degeneration.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Behavior, Animal; Cell Count; Corpus Striatum | 2004 |
3-Nitropropionic acid-induced neurotoxicity--assessed by ultra high resolution positron emission tomography with comparison to magnetic resonance spectroscopy.
Topics: Acute Disease; Animals; Behavior, Animal; Body Weight; Brain; Choline; Chronic Disease; Disease Mode | 2004 |
UCM707, an inhibitor of the anandamide uptake, behaves as a symptom control agent in models of Huntington's disease and multiple sclerosis, but fails to delay/arrest the progression of different motor-related disorders.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Arachidonic Acids; Brain Chemistry; D | 2006 |
The mitochondrial toxin 3-nitropropionic acid induces striatal neurodegeneration via a c-Jun N-terminal kinase/c-Jun module.
Topics: Active Transport, Cell Nucleus; Animals; Apoptosis; Cells, Cultured; Corpus Striatum; Disease Models | 2002 |
Corticostriatopallidal neuroprotection by adenovirus-mediated ciliary neurotrophic factor gene transfer in a rat model of progressive striatal degeneration.
Topics: Adenoviridae; Animals; Behavior, Animal; Cell Count; Cell Survival; Cerebral Cortex; Ciliary Neurotr | 2002 |