3-nitropropionic acid has been researched along with Chronic Disease in 4 studies
3-nitropropionic acid: succinate dehydrogenase inactivator; biosynthesized by FABACEAE plants from ASPARAGINE
3-nitropropanoic acid : A C-nitro compound that is propanoic acid in which one of the methyl hydrogens has been replaced by a nitro group.
Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Striatal cell death in Huntington's Disease (HD) may involve mitochondrial defects, NMDA-mediated excitotoxicity, and activation of death effector proteases such as caspases and calpain." | 1.32 | Calpain is a major cell death effector in selective striatal degeneration induced in vivo by 3-nitropropionate: implications for Huntington's disease. ( Bizat, N; Boyer, F; Brouillet, E; Créminon, C; Escartin, C; Hantraye, P; Hermel, JM; Jacquard, C; Kajewski, S; Ouary, S, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Blum, D | 1 |
| Galas, MC | 1 |
| Gall, D | 1 |
| Cuvelier, L | 1 |
| Schiffmann, SN | 1 |
| Bizat, N | 1 |
| Hermel, JM | 1 |
| Boyer, F | 1 |
| Jacquard, C | 1 |
| Créminon, C | 1 |
| Ouary, S | 1 |
| Escartin, C | 1 |
| Hantraye, P | 1 |
| Kajewski, S | 1 |
| Brouillet, E | 1 |
| Brownell, AL | 1 |
| Chen, YI | 1 |
| Yu, M | 1 |
| Wang, X | 1 |
| Dedeoglu, A | 1 |
| Cicchetti, F | 1 |
| Jenkins, BG | 1 |
| Beal, MF | 2 |
4 other studies available for 3-nitropropionic acid and Chronic Disease
| Article | Year |
|---|---|
Striatal and cortical neurochemical changes induced by chronic metabolic compromise in the 3-nitropropionic model of Huntington's disease.
Topics: Animals; Brain Chemistry; Cerebral Cortex; Chronic Disease; Corpus Striatum; Disease Models, Animal; | 2002 |
Calpain is a major cell death effector in selective striatal degeneration induced in vivo by 3-nitropropionate: implications for Huntington's disease.
Topics: Acute Disease; Animals; Calpain; Caspases; Cell Death; Chronic Disease; Corpus Striatum; Disease Mod | 2003 |
3-Nitropropionic acid-induced neurotoxicity--assessed by ultra high resolution positron emission tomography with comparison to magnetic resonance spectroscopy.
Topics: Acute Disease; Animals; Behavior, Animal; Body Weight; Brain; Choline; Chronic Disease; Disease Mode | 2004 |
Limited-time exposure to mitochondrial toxins may lead to chronic progressive neurodegenerative diseases.
Topics: Animals; Cebus; Chronic Disease; Humans; Mitochondria; Neurodegenerative Diseases; Neurotoxins; Nitr | 2000 |