3-nitropropionic acid has been researched along with Atherosclerotic Parkinsonism in 7 studies
3-nitropropionic acid: succinate dehydrogenase inactivator; biosynthesized by FABACEAE plants from ASPARAGINE
3-nitropropanoic acid : A C-nitro compound that is propanoic acid in which one of the methyl hydrogens has been replaced by a nitro group.
Excerpt | Relevance | Reference |
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"We developed a primate model of striatonigral degeneration (SND), the neuropathology underlying levodopa-unresponsive parkinsonism associated with multiple systemic atrophy (MSA-P), by sequential systemic administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and 3-nitropropionic acid (3NP) in a Macaca fascicularis monkey." | 1.31 | Toward a primate model of L-dopa-unresponsive parkinsonism mimicking striatonigral degeneration. ( Aubert, I; Bezard, E; Fernagut, PO; Ghorayeb, I; Poewe, W; Tison, F; Wenning, GK, 2000) |
"Cotreatment with riluzole (4 mg/kg i." | 1.30 | Riluzole reduces incidence of abnormal movements but not striatal cell death in a primate model of progressive striatal degeneration. ( Brouillet, E; Guyot, MC; Hantraye, P; Mary, V; Palfi, S; Peschanski, M; Riche, D; Stutzmann, JM; Wahl, F, 1997) |
Timeframe | Studies, this research(%) | All Research% |
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pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (14.29) | 18.2507 |
2000's | 6 (85.71) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Tantucci, M | 1 |
Mariucci, G | 1 |
Taha, E | 1 |
Spaccatini, C | 1 |
Tozzi, A | 1 |
Luchetti, E | 1 |
Calabresi, P | 1 |
Ambrosini, MV | 1 |
Imamura, K | 1 |
Takeshima, T | 1 |
Kashiwaya, Y | 1 |
Nakaso, K | 1 |
Nakashima, K | 1 |
Ayala, A | 1 |
Venero, JL | 1 |
Cano, J | 1 |
Machado, A | 1 |
Palfi, S | 2 |
Riche, D | 1 |
Brouillet, E | 1 |
Guyot, MC | 1 |
Mary, V | 1 |
Wahl, F | 1 |
Peschanski, M | 1 |
Stutzmann, JM | 1 |
Hantraye, P | 1 |
Klivenyi, P | 1 |
Andreassen, OA | 1 |
Ferrante, RJ | 1 |
Dedeoglu, A | 1 |
Mueller, G | 1 |
Lancelot, E | 1 |
Bogdanov, M | 1 |
Andersen, JK | 1 |
Jiang, D | 1 |
Beal, MF | 1 |
Leventhal, L | 1 |
Goetz, CG | 1 |
Hantraye, T | 1 |
Roitberg, BZ | 1 |
Sramek, J | 1 |
Emborg, M | 1 |
Kordower, JH | 1 |
Ghorayeb, I | 1 |
Fernagut, PO | 1 |
Aubert, I | 1 |
Bezard, E | 1 |
Poewe, W | 1 |
Wenning, GK | 1 |
Tison, F | 1 |
1 review available for 3-nitropropionic acid and Atherosclerotic Parkinsonism
Article | Year |
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Mitochondrial toxins and neurodegenerative diseases.
Topics: Animals; Disease Models, Animal; Humans; Huntington Disease; Mitochondria; MPTP Poisoning; Neurodege | 2007 |
6 other studies available for 3-nitropropionic acid and Atherosclerotic Parkinsonism
Article | Year |
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Induction of heat shock protein 70 reduces the alteration of striatal electrical activity caused by mitochondrial impairment.
Topics: Animals; Corpus Striatum; Electron Transport Complex I; Electron Transport Complex II; Heat-Shock Re | 2009 |
D-beta-hydroxybutyrate protects dopaminergic SH-SY5Y cells in a rotenone model of Parkinson's disease.
Topics: 3-Hydroxybutyric Acid; Caspase 3; Caspase 9; Cell Line, Tumor; Cell Survival; Dopamine; Fluorescent | 2006 |
Riluzole reduces incidence of abnormal movements but not striatal cell death in a primate model of progressive striatal degeneration.
Topics: Acetylcholinesterase; Animals; Antiparkinson Agents; Apomorphine; Caudate Nucleus; Corpus Striatum; | 1997 |
Mice deficient in cellular glutathione peroxidase show increased vulnerability to malonate, 3-nitropropionic acid, and 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemist | 2000 |
Delayed onset of progressive dystonia following subacute 3-nitropropionic acid treatment in Cebus apella monkeys.
Topics: Animals; Basal Ganglia; Brain Mapping; Cebus; Chorea; Dystonia; Mitochondria; Neurotoxins; Nitro Com | 2000 |
Toward a primate model of L-dopa-unresponsive parkinsonism mimicking striatonigral degeneration.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antiparkinson Agents; Brain Mapping; Corpus S | 2000 |