3-nitropropionic acid has been researched along with Astrocytosis in 8 studies
3-nitropropionic acid: succinate dehydrogenase inactivator; biosynthesized by FABACEAE plants from ASPARAGINE
3-nitropropanoic acid : A C-nitro compound that is propanoic acid in which one of the methyl hydrogens has been replaced by a nitro group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Reactive astrocytosis seems to be strongly implicated in the development and maintenance of inflammatory and neurodegenerative disorders." | 5.36 | Discriminative behavioral assessment unveils remarkable reactive astrocytosis and early molecular correlates in basal ganglia of 3-nitropropionic acid subchronic treated rats. ( Bianco, MR; Cirillo, G; Maggio, N; Papa, M; Sellitti, S; Vollono, C, 2010) |
| "Astrogliosis and glial scars were another finding of this study." | 1.56 | The effect of 3-nitropropionic acid on behavioral dysfunction, neuron loss and gliosis in the brain of adult male rats: The case of prefrontal cortex, hippocampus and the cerebellum. ( Abdollahifar, MA; Aliaghaei, A; Ezi, S; Joneidi, M; Kahrizirad, F; Khatmi, A; Moghaddam, MH; Mohammadzadeh, I; Norozian, M; Rafiei, R; Torabi, A, 2020) |
| "Reactive astrocytosis seems to be strongly implicated in the development and maintenance of inflammatory and neurodegenerative disorders." | 1.36 | Discriminative behavioral assessment unveils remarkable reactive astrocytosis and early molecular correlates in basal ganglia of 3-nitropropionic acid subchronic treated rats. ( Bianco, MR; Cirillo, G; Maggio, N; Papa, M; Sellitti, S; Vollono, C, 2010) |
| "Celastrol is a potent anti-inflammatory and antioxidant compound extracted from a perennial creeping plant belonging to the Celastraceae family." | 1.33 | Celastrol protects against MPTP- and 3-nitropropionic acid-induced neurotoxicity. ( Beal, MF; Calingasan, NY; Chen, J; Cleren, C, 2005) |
| " In astrocyte cultures, the toxic effects of 3-NPA were associated with corresponding increases in the NO(2)(-) level, and this toxicity was attenuated by hemoglobin (Hb; 20 microM), which quenches NO." | 1.33 | Involvement of nitric oxide in 3-nitropropionic acid-induced striatal toxicity in rats. ( Baba, H; Deshpande, SB; Hida, H; Masuda, T; Nishino, H; Takei-Io, N, 2006) |
| "Striatal gliosis induced by 3-NP treatment was prevented by (+/-)-huprine Y pretreatment, as demonstrated by the attenuation of both the increase in [(3)H]PK 11195 specific binding indicative of microgliosis and the expression of hsp27 kDa, a chaperone expressed mainly in astrocytes." | 1.32 | Neuroprotective effects of (+/-)-huprine Y on in vitro and in vivo models of excitoxicity damage. ( Camins, A; Camps, P; Canudas, AM; Jiménez, A; Muñoz-Torrero, D; Pallàs, M; Pubill, D; Sureda, FX; Verdaguer, E, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (62.50) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Torabi, A | 1 |
| Joneidi, M | 1 |
| Mohammadzadeh, I | 1 |
| Abdollahifar, MA | 2 |
| Khatmi, A | 1 |
| Ezi, S | 1 |
| Moghaddam, MH | 1 |
| Rafiei, R | 1 |
| Kahrizirad, F | 1 |
| Norozian, M | 1 |
| Aliaghaei, A | 2 |
| Ebrahimi, MJ | 1 |
| Boroujeni, ME | 1 |
| Khodagholi, F | 1 |
| Meftahi, G | 1 |
| Ahmadi, H | 1 |
| Danyali, S | 1 |
| Daftari, M | 1 |
| Sadeghi, Y | 1 |
| Cirillo, G | 1 |
| Maggio, N | 1 |
| Bianco, MR | 1 |
| Vollono, C | 1 |
| Sellitti, S | 1 |
| Papa, M | 1 |
| Canudas, AM | 1 |
| Pubill, D | 1 |
| Sureda, FX | 1 |
| Verdaguer, E | 1 |
| Camps, P | 1 |
| Muñoz-Torrero, D | 1 |
| Jiménez, A | 1 |
| Camins, A | 1 |
| Pallàs, M | 1 |
| Hanbury, R | 1 |
| Chen, EY | 1 |
| Wuu, J | 1 |
| Kordower, JH | 1 |
| Cleren, C | 1 |
| Calingasan, NY | 1 |
| Chen, J | 1 |
| Beal, MF | 1 |
| Deshpande, SB | 1 |
| Hida, H | 1 |
| Takei-Io, N | 1 |
| Masuda, T | 1 |
| Baba, H | 1 |
| Nishino, H | 1 |
| Silva-Adaya, D | 1 |
| Pérez-De La Cruz, V | 1 |
| Herrera-Mundo, MN | 1 |
| Mendoza-Macedo, K | 1 |
| Villeda-Hernández, J | 1 |
| Binienda, Z | 1 |
| Ali, SF | 1 |
| Santamaría, A | 1 |
8 other studies available for 3-nitropropionic acid and Astrocytosis
| Article | Year |
|---|---|
The effect of 3-nitropropionic acid on behavioral dysfunction, neuron loss and gliosis in the brain of adult male rats: The case of prefrontal cortex, hippocampus and the cerebellum.
Topics: Animals; Brain; Cerebellum; Gliosis; Hippocampus; Male; Mycotoxins; Nitro Compounds; Prefrontal Cort | 2020 |
Human Umbilical Cord Matrix Stem Cells Reverse Oxidative Stress-Induced Cell Death and Ameliorate Motor Function and Striatal Atrophy in Rat Model of Huntington Disease.
Topics: Animals; Antigens, CD; Cell Death; Cell Differentiation; Cell Line; Convulsants; Cord Blood Stem Cel | 2018 |
Discriminative behavioral assessment unveils remarkable reactive astrocytosis and early molecular correlates in basal ganglia of 3-nitropropionic acid subchronic treated rats.
Topics: Animals; Astrocytes; Basal Ganglia; Basal Ganglia Diseases; Behavior, Animal; Disability Evaluation; | 2010 |
Neuroprotective effects of (+/-)-huprine Y on in vitro and in vivo models of excitoxicity damage.
Topics: Aminoquinolines; Animals; Binding, Competitive; Calcium; Cell Death; Cells, Cultured; Cerebellum; Co | 2003 |
Knockout of p75NTR does not alter the viability of striatal neurons following a metabolic or excitotoxic injury.
Topics: Animals; Astrocytes; Brain Injuries; Cell Death; Cell Survival; Energy Metabolism; Gliosis; Immunohi | 2003 |
Celastrol protects against MPTP- and 3-nitropropionic acid-induced neurotoxicity.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Anti-Inflammatory Agents; Antioxidants; Cell | 2005 |
Involvement of nitric oxide in 3-nitropropionic acid-induced striatal toxicity in rats.
Topics: Animals; Astrocytes; Cells, Cultured; Convulsants; Corpus Striatum; Disease Models, Animal; Dose-Res | 2006 |
Excitotoxic damage, disrupted energy metabolism, and oxidative stress in the rat brain: antioxidant and neuroprotective effects of L-carnitine.
Topics: Animals; Antioxidants; Brain; Carnitine; Convulsants; Disease Models, Animal; Dose-Response Relation | 2008 |