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3-nitropropionic acid and Anoxia, Brain

3-nitropropionic acid has been researched along with Anoxia, Brain in 13 studies

3-nitropropionic acid: succinate dehydrogenase inactivator; biosynthesized by FABACEAE plants from ASPARAGINE
3-nitropropanoic acid : A C-nitro compound that is propanoic acid in which one of the methyl hydrogens has been replaced by a nitro group.

Research Excerpts

ExcerptRelevanceReference
"The serotonin selective reuptake inhibitor fluoxetine (Flx) has tried to treat patients suffered acute ischemic stroke because of its possible neuroprotective actions."7.78Optimal dosages of fluoxetine in the treatment of hypoxic brain injury induced by 3-nitropropionic acid: implications for the adjunctive treatment of patients after acute ischemic stroke. ( Sun, Y; Sun, ZQ; Yang, G; Zhou, CH; Zhu, BG; Zhu, RS, 2012)
"The serotonin selective reuptake inhibitor fluoxetine (Flx) has tried to treat patients suffered acute ischemic stroke because of its possible neuroprotective actions."3.78Optimal dosages of fluoxetine in the treatment of hypoxic brain injury induced by 3-nitropropionic acid: implications for the adjunctive treatment of patients after acute ischemic stroke. ( Sun, Y; Sun, ZQ; Yang, G; Zhou, CH; Zhu, BG; Zhu, RS, 2012)
" We tested the ability of Bcl-xl overexpression to protect primary cultures of embryonic rat septal neurons subjected to one of four different stresses: 6 h of combined oxygen-glucose deprivation, which produces rapid cell death, or a 24 h exposure to hypoglycemia, hyperglycemia, or 1mM 3-nitropropionic acid (an inhibitor of mitochondrial respiration), which results in a more slowly-developing death."3.73Overexpression of Bcl-xl protects septal neurons from prolonged hypoglycemia and from acute ischemia-like stress. ( Barrett, JN; Nonner, D; Panickar, KS, 2005)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (38.46)18.2507
2000's7 (53.85)29.6817
2010's1 (7.69)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Akopian, G1
Crawford, C1
Beal, MF1
Cappelletti, M1
Jakowec, MW1
Petzinger, GM1
Zheng, L1
Gheorghe, SL1
Reichel, CM1
Chow, R1
Walsh, JP1
Zhu, BG2
Sun, Y1
Sun, ZQ1
Yang, G1
Zhou, CH1
Zhu, RS1
Büchner, M2
Huber, R2
Sturchler-Pierrat, C1
Staufenbiel, M1
Riepe, MW7
Münch, C1
Leven, A1
Stamm, S1
Einkörn, H1
Schwalenstöcker, B1
Ludolph, AC4
Meyer, T1
von Arnim, CA2
Hellweg, R2
Panickar, KS1
Nonner, D1
Barrett, JN1
Kasischke, K3
Gericke, CA1
Löwe, A1
Esclaire, F1
Schreiber, S1
Nakase, H2
Kempski, O1
Dirnagl, U1
Hugon, J1
Binienda, Z1
Nishino, H1
Nakajima, K1
Kumazaki, M1
Fukuda, A1
Muramatsu, K1
Deshpande, SB1
Inubushi, T1
Morikawa, S1
Borlongan, CV1
Sanberg, PR1
Timmler, M1
Aketa, S1
Nishi, N1
Kamada, Y1
Hiramatsu, K1
Sakaki, T1

Other Studies

13 other studies available for 3-nitropropionic acid and Anoxia, Brain

ArticleYear
Decreased striatal dopamine release underlies increased expression of long-term synaptic potentiation at corticostriatal synapses 24 h after 3-nitropropionic-acid-induced chemical hypoxia.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, Sep-17, Volume: 28, Issue:38

    Topics: Animals; Cerebral Cortex; Convulsants; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine A

2008
Optimal dosages of fluoxetine in the treatment of hypoxic brain injury induced by 3-nitropropionic acid: implications for the adjunctive treatment of patients after acute ischemic stroke.
    CNS neuroscience & therapeutics, 2012, Volume: 18, Issue:7

    Topics: Animals; Brain Ischemia; Fluoxetine; Hypoxia, Brain; Male; Mice; Nitro Compounds; Propionates; Rando

2012
Impaired hypoxic tolerance and altered protein binding of NADH in presymptomatic APP23 transgenic mice.
    Neuroscience, 2002, Volume: 114, Issue:2

    Topics: Action Potentials; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Disease Models, Anima

2002
Differential regulation of 5' splice variants of the glutamate transporter EAAT2 in an in vivo model of chemical hypoxia induced by 3-nitropropionic acid.
    Journal of neuroscience research, 2003, Mar-15, Volume: 71, Issue:6

    Topics: Alternative Splicing; Animals; Brain; Cloning, Molecular; Convulsants; Excitatory Amino Acid Transpo

2003
Regional selectivity of amyloid mRNA expression and neurotrophins on repetitive inhibition of oxidative phosphorylation.
    Journal of neural transmission (Vienna, Austria : 1996), 2005, Volume: 112, Issue:4

    Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Brain; Brain Chemistry; Brain-Derived Ne

2005
Overexpression of Bcl-xl protects septal neurons from prolonged hypoglycemia and from acute ischemia-like stress.
    Neuroscience, 2005, Volume: 135, Issue:1

    Topics: Adenosine Triphosphate; Animals; Antimetabolites; bcl-X Protein; Brain Ischemia; Caspase 3; Caspases

2005
Increase of hypoxic tolerance in rat hippocampal slices following 3-nitropropionic acid is not mediated by endogenous nerve growth factor.
    Neuroscience letters, 1996, Jun-14, Volume: 211, Issue:1

    Topics: Animals; Enzyme Inhibitors; Hippocampus; Hypoxia, Brain; In Vitro Techniques; Ischemic Preconditioni

1996
NMDA-antagonists reverse increased hypoxic tolerance by preceding chemical hypoxia.
    Neuroscience letters, 1996, Aug-23, Volume: 214, Issue:2-3

    Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Antihypertensive Agents;

1996
Increased hypoxic tolerance by chemical inhibition of oxidative phosphorylation: "chemical preconditioning".
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1997, Volume: 17, Issue:3

    Topics: Adenosine Triphosphate; Animals; Brain Ischemia; Cell Hypoxia; Enzyme Inhibitors; Free Radicals; Gly

1997
Compensatory long-term effect of perinatal hypoxia-ischemia. A possible mechanism for neuroprotection?
    Annals of the New York Academy of Sciences, 1997, Oct-15, Volume: 825

    Topics: Animals; Animals, Newborn; Brain; Brain Ischemia; Conditioning, Operant; Energy Metabolism; Fetus; H

1997
Estrogen protects against while testosterone exacerbates vulnerability of the lateral striatal artery to chemical hypoxia by 3-nitropropionic acid.
    Neuroscience research, 1998, Volume: 30, Issue:4

    Topics: Animals; Animals, Newborn; Antihypertensive Agents; Antineoplastic Agents, Hormonal; Astrocytes; Blo

1998
Adenosine receptor up-regulation: initiated upon preconditioning but not upheld.
    Neuroreport, 2000, Apr-27, Volume: 11, Issue:6

    Topics: Animals; Cell Hypoxia; Cells, Cultured; Hippocampus; Hypoxia, Brain; In Vitro Techniques; Ischemic P

2000
[Neuroprotective effect of a neurotoxin, 3-nitropropionic acid, against hypoxic damage to the gerbil hippocampus: neuroprotection after the onset of hypoxic depolarization].
    No to shinkei = Brain and nerve, 2001, Volume: 53, Issue:3

    Topics: Animals; Electrophysiology; Gerbillinae; Hippocampus; Hypoxia, Brain; In Vitro Techniques; Ischemic

2001