3-nitropropionic acid has been researched along with Amyotrophic Lateral Sclerosis in 4 studies
3-nitropropionic acid: succinate dehydrogenase inactivator; biosynthesized by FABACEAE plants from ASPARAGINE
3-nitropropanoic acid : A C-nitro compound that is propanoic acid in which one of the methyl hydrogens has been replaced by a nitro group.
Amyotrophic Lateral Sclerosis: A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cleren, C | 1 |
| Calingasan, NY | 1 |
| Starkov, A | 1 |
| Jacquard, C | 1 |
| Chen, J | 1 |
| Brouillet, E | 1 |
| Beal, MF | 3 |
| Huang, QY | 1 |
| Yu, L | 1 |
| Ferrante, RJ | 2 |
| Chen, JF | 1 |
| Bogdanov, MB | 1 |
| Ramos, LE | 1 |
| Xu, Z | 1 |
| Andreassen, OA | 1 |
| Klivenyi, P | 1 |
| Klein, AM | 1 |
| Dedeoglu, A | 1 |
| Albers, DS | 1 |
| Kowall, NW | 1 |
4 other studies available for 3-nitropropionic acid and Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
Promethazine protects against 3-nitropropionic acid-induced neurotoxicity.
Topics: Amyotrophic Lateral Sclerosis; Animals; Brain Ischemia; Disease Models, Animal; Huntington Disease; | 2010 |
Mutant SOD1G93A in bone marrow-derived cells exacerbates 3-nitropropionic acid induced striatal damage in mice.
Topics: Amyotrophic Lateral Sclerosis; Animals; Bone Marrow Cells; Bone Marrow Transplantation; Corpus Stria | 2007 |
Elevated "hydroxyl radical" generation in vivo in an animal model of amyotrophic lateral sclerosis.
Topics: Amyotrophic Lateral Sclerosis; Animals; Corpus Striatum; Humans; Hydroxybenzoates; Hydroxyl Radical; | 1998 |
Transgenic ALS mice show increased vulnerability to the mitochondrial toxins MPTP and 3-nitropropionic acid.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Amyotrophic Lateral Sc | 2001 |