Page last updated: 2024-10-21

3-nitropropionic acid and Alzheimer Disease

3-nitropropionic acid has been researched along with Alzheimer Disease in 6 studies

3-nitropropionic acid: succinate dehydrogenase inactivator; biosynthesized by FABACEAE plants from ASPARAGINE
3-nitropropanoic acid : A C-nitro compound that is propanoic acid in which one of the methyl hydrogens has been replaced by a nitro group.

Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (83.33)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
O'Connor, T1
Sadleir, KR1
Maus, E1
Velliquette, RA1
Zhao, J1
Cole, SL1
Eimer, WA1
Hitt, B1
Bembinster, LA1
Lammich, S1
Lichtenthaler, SF1
Hébert, SS1
De Strooper, B1
Haass, C1
Bennett, DA1
Vassar, R1
Niatsetskaya, Z1
Basso, M1
Speer, RE1
McConoughey, SJ1
Coppola, G1
Ma, TC1
Ratan, RR1
Büchner, M2
Huber, R2
Sturchler-Pierrat, C1
Staufenbiel, M1
Riepe, MW3
von Arnim, CA2
Hellweg, R1
Verstege, E1
Etrich, SM1
Arias, C1
Montiel, T1
Quiroz-Báez, R1
Massieu, L1

Other Studies

6 other studies available for 3-nitropropionic acid and Alzheimer Disease

ArticleYear
Phosphorylation of the translation initiation factor eIF2alpha increases BACE1 levels and promotes amyloidogenesis.
    Neuron, 2008, Dec-26, Volume: 60, Issue:6

    Topics: Age Factors; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precu

2008
HIF prolyl hydroxylase inhibitors prevent neuronal death induced by mitochondrial toxins: therapeutic implications for Huntington's disease and Alzheimer's disease.
    Antioxidants & redox signaling, 2010, Volume: 12, Issue:4

    Topics: Alzheimer Disease; Animals; Cell Death; Enzyme Inhibitors; Huntington Disease; Hypoxia-Inducible Fac

2010
Impaired hypoxic tolerance and altered protein binding of NADH in presymptomatic APP23 transgenic mice.
    Neuroscience, 2002, Volume: 114, Issue:2

    Topics: Action Potentials; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Disease Models, Anima

2002
Regional selectivity of amyloid mRNA expression and neurotrophins on repetitive inhibition of oxidative phosphorylation.
    Journal of neural transmission (Vienna, Austria : 1996), 2005, Volume: 112, Issue:4

    Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Brain; Brain Chemistry; Brain-Derived Ne

2005
Mechanisms of hypoxic tolerance in presymptomatic APP23 transgenic mice.
    Mechanisms of ageing and development, 2006, Volume: 127, Issue:2

    Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Disease Models, Animal; Gene Expression

2006
beta-Amyloid neurotoxicity is exacerbated during glycolysis inhibition and mitochondrial impairment in the rat hippocampus in vivo and in isolated nerve terminals: implications for Alzheimer's disease.
    Experimental neurology, 2002, Volume: 176, Issue:1

    Topics: Adenosine Triphosphate; Alzheimer Disease; Amyloid beta-Peptides; Animals; Disease Models, Animal; D

2002