3-n-butylphthalide has been researched along with Innate Inflammatory Response in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (7.14) | 29.6817 |
| 2010's | 6 (42.86) | 24.3611 |
| 2020's | 7 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, X; Deng, S; Lu, W; Ren, Y; Zhang, Y | 1 |
| Hong, Z; Li, S; Li, Y; Liu, Y; Wang, J; Xie, S | 1 |
| Cai, C; Cui, Y; Deng, L; He, B; Wang, L; Wang, X; Yang, Y; Zhang, H; Zhou, W; Zhu, B | 1 |
| Li, MR; Li, NS; Lu, LQ; Luo, XJ; Peng, J; Peng, JY; Tang, LJ | 1 |
| Bai, M; Jiang, GX; Pan, CL; Zhang, YM; Zhang, Z | 1 |
| Chen, D; Geng, C; Guo, Y; Han, W; Hao, G; Jiang, P; Yang, M; Yi, Q; Zhang, J | 1 |
| Fu, D; Liu, R; Liu, X; Pu, X; Sun, Y; Wang, M; Wu, H; Zhao, X | 1 |
| Chen, T; Dong, Y; Fan, Y; Li, X; Lin, W; Liu, F; Wang, N; Wen, J; Yin, J; Zhang, Q | 1 |
| Cao, L; Dang, R; Fu, Y; Han, W; Jiang, P; Liao, D; Wang, J; Xiang, D; Xu, P; Yao, D | 1 |
| Du, R; Shi, ZB; Teng, JF; Wang, Y; Zhao, XY | 1 |
| Cai, J; Lei, H; Li, L; Li, PP; Peng, Y; Wang, L; Wang, XL; Xu, SF; Zhang, Y; Zhao, CY | 1 |
| Guo, ZF; Li, YS; Song, JG; Xu, YM; Zhang, P | 1 |
| Abdoulaye, IA; Guo, YJ | 1 |
| Feng, YP; Xu, HL | 1 |
2 review(s) available for 3-n-butylphthalide and Innate Inflammatory Response
| Article | Year |
|---|---|
Role of Butylphthalide in Immunity and Inflammation: Butylphthalide May Be a Potential Therapy for Anti-Inflammation and Immunoregulation.
Topics: Anti-Inflammatory Agents; Benzofurans; Humans; Inflammation; Neuroprotective Agents | 2022 |
A Review of Recent Advances in Neuroprotective Potential of 3-N-Butylphthalide and Its Derivatives.
Topics: Apium; Apoptosis; Benzofurans; Humans; Inflammation; Nervous System Diseases; Neuroprotective Agents; Oxidative Stress; Plant Extracts | 2016 |
1 trial(s) available for 3-n-butylphthalide and Innate Inflammatory Response
| Article | Year |
|---|---|
Clinical study of Butylphthalide combined with Xue Shuan Tong on serum inflammatory factors and prognosis effect of patients with cerebral infarction.
Topics: Aged; Aged, 80 and over; Benzofurans; Calcitonin Gene-Related Peptide; Carotid Arteries; Carotid Intima-Media Thickness; Cerebral Infarction; Drugs, Chinese Herbal; Female; Humans; Inflammation; Interleukin-2; Male; Middle Aged; Nervous System Diseases; Plaque, Atherosclerotic; Prognosis | 2015 |
11 other study(ies) available for 3-n-butylphthalide and Innate Inflammatory Response
| Article | Year |
|---|---|
Efficacy of Butylphthalide in Combination with Edaravone in the Treatment of Acute Ischemic Stroke and the Effect on Serum Inflammatory Factors.
Topics: Benzofurans; Edaravone; Humans; Inflammation; Interleukin-6; Ischemic Stroke; Stroke | 2023 |
A comparative study of the neuroprotective effects of dl-3-n-butylphthalide and edaravone dexborneol on cerebral ischemic stroke rats.
Topics: Animals; Brain Ischemia; Edaravone; Infarction, Middle Cerebral Artery; Inflammation; Ischemic Stroke; Kelch-Like ECH-Associated Protein 1; Neuroprotective Agents; NF-E2-Related Factor 2; NF-kappa B; Rats; Stroke | 2023 |
DL-3-n-butylphthalide improves the endothelium-dependent vasodilation in high-fat diet-fed ApoE
Topics: Animals; Apolipoproteins E; Apoptosis; Atherosclerosis; Atorvastatin; Cytokines; Diet, High-Fat; Endothelium; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Ischemic Stroke; Male; Mice; Mice, Knockout; Necroptosis; Vasodilation | 2023 |
Effects of butylphthalide on oxidative stress and inflammatory response in rats with myocardial infarction through Akt/Nrf2 signaling pathway.
Topics: Animals; Benzofurans; Disease Models, Animal; Inflammation; Male; Myocardial Infarction; Neuroprotective Agents; NF-E2-Related Factor 2; Oxidative Stress; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction | 2019 |
The impact of Dl-3-n-butylphthalide on the lipidomics of the hippocampus in a rat model of lipopolysaccharide-induced depression.
Topics: Animals; Benzofurans; Depression; Hippocampus; Inflammation; Lipid Metabolism; Lipidomics; Lipopolysaccharides; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley | 2020 |
Dl-3-n-butylphthalide inhibits neuroinflammation by stimulating foxp3 and Ki-67 in an ischemic stroke model.
Topics: Animals; Benzofurans; Brain; Caspase 1; Cyclic AMP Response Element-Binding Protein; Forkhead Transcription Factors; Infarction, Middle Cerebral Artery; Inflammation; Ischemic Stroke; Ki-67 Antigen; Molecular Docking Simulation; Neovascularization, Physiologic; Nerve Regeneration; Neuroprotective Agents; NLR Family, Pyrin Domain-Containing 3 Protein; Phospholipids; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2021 |
Dl-3-n-butylphthalide pretreatment attenuates renal ischemia/reperfusion injury.
Topics: Animals; Apoptosis; Benzofurans; Caspase 3; Cell Hypoxia; Cell Survival; Creatinine; Disease Models, Animal; Immunohistochemistry; Inflammation; Kidney; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Oxidative Stress; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Reperfusion Injury | 2021 |
Neuroprotective Effects of dl-3-n-Butylphthalide against Doxorubicin-Induced Neuroinflammation, Oxidative Stress, Endoplasmic Reticulum Stress, and Behavioral Changes.
Topics: Antibiotics, Antineoplastic; Behavioral Symptoms; Benzofurans; Doxorubicin; Endoplasmic Reticulum Stress; Humans; Inflammation; Neuroprotective Agents; Oxidative Stress | 2018 |
L-3-n-Butylphthalide attenuates neuroinflammatory responses by downregulating JNK activation and upregulating Heme oxygenase-1 in lipopolysaccharide-treated mice.
Topics: Animals; Benzofurans; Brain; Cytokines; Disease Models, Animal; Heme Oxygenase-1; Immunologic Factors; Inflammation; Lipopolysaccharides; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Microglia; Mitogen-Activated Protein Kinases; Molecular Structure; Neuroprotective Agents; Phosphorylation; Signal Transduction; Tumor Necrosis Factor-alpha; Up-Regulation | 2016 |
N-Butylphthalide (NBP) ameliorated cerebral ischemia reperfusion-induced brain injury via HGF-regulated TLR4/NF-κB signaling pathway.
Topics: Animals; Astrocytes; Benzofurans; Brain Ischemia; Cell Survival; Hepatocyte Growth Factor; Humans; Inflammation; Lipopolysaccharides; Male; NF-kappa B; Rats, Sprague-Dawley; Reperfusion Injury; Signal Transduction; Toll-Like Receptor 4; Up-Regulation | 2016 |
Inhibitory effects of chiral 3-n-butylphthalide on inflammation following focal ischemic brain injury in rats.
Topics: Animals; Benzofurans; Brain Ischemia; Cerebral Cortex; Infarction, Middle Cerebral Artery; Inflammation; Intercellular Adhesion Molecule-1; Leukocyte Count; Male; Neuroprotective Agents; Neutrophils; Peroxidase; Rats; Rats, Wistar; Reperfusion Injury; RNA, Messenger; Tumor Necrosis Factor-alpha | 2000 |