Page last updated: 2024-08-24

3-n-butylphthalide and Cerebral Infarction

3-n-butylphthalide has been researched along with Cerebral Infarction in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (3.85)18.2507
2000's0 (0.00)29.6817
2010's9 (34.62)24.3611
2020's16 (61.54)2.80

Authors

AuthorsStudies
Che, F; Dong, X; Feng, L; Jing, R; Pei, Q; Qian, J; Ren, G; Xue, L1
Guo, Y; Hu, H; Liu, H; Liu, Y; Xu, G; Yan, J1
Fu, B; Gao, G; Meng, S1
Zhu, C1
Shen, QQ; Tong, XW; Wang, W; Wu, H1
Che, J; Wang, Z1
Abuduxukuer, R; Guo, ZN; He, Q; Huang, S; Qu, Y; Ren, J; Sun, X; Yang, Y; Zhang, K1
Liu, X; Ma, Y; Wang, Y; Zhang, Q1
Guo, J; Guo, W; Xing, Y2
Luan, X; Wang, X; Yang, Z1
Dong, YT; Hu, FY; Li, TT; Liu, Y; Zhang, XL; Zhang, Y1
Chen, G; Deng, Y; Jiang, W; Li, X; Shangguan, S; Zhou, F; Zou, W1
Liu, JX; Ren, JG; Wang, M; Yao, MJ1
Feng, Y; Gao, P; Gui, L; Pan, W; Qin, B; Sima, D; Wang, J; Wang, M; Wang, Q; Yuan, Y1
Gao, YL; Guo, JJ; Wang, M; Wang, ZY; Yu, XF1
Chang, H; Li, H; Wang, D; Yin, A; Yin, J1
Feng, S; Gu, F; Hu, L; Mao, S; Zang, Y; Zhang, C; Zhao, S1
Fan, XH; Li, K; Luo, CJ; Ning, LP; Tang, SC; Xue, P; Zhang, KH1
Ma, QS; Ma, YB; Mi, LX; Nai, Y; Song, DJ; Zhang, LH; Zhao, YJ1
Cheng, W; Dong, LF; Liao, W; Zhong, Y1
Gao, P; Hu, J; Li, B; Wen, Q; Wu, Y1
Guo, L; Niu, LJ; Qi, FM; Zhou, Y1
Du, R; Shi, ZB; Teng, JF; Wang, Y; Zhao, XY1
Jiang, Y; Sun, L; Wang, J; Xuan, X1
Feng, YP; Liu, XG1

Reviews

2 review(s) available for 3-n-butylphthalide and Cerebral Infarction

ArticleYear
Effects of NBP injection on the inflammatory response, oxidative stress response and vascular endothelial function in patients with ACI: A systematic review and meta-analysis.
    Medicine, 2023, Mar-10, Volume: 102, Issue:10

    Topics: Cerebral Infarction; Drugs, Chinese Herbal; Humans; Retrospective Studies; Stroke; Vascular Endothelial Growth Factor A

2023
[Advances in research on pharmacological and neuroprotective effects of traditional Chinese medicine after cerebral ischemia].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2020, Volume: 45, Issue:3

    Topics: Benzofurans; Brain Ischemia; Cerebral Infarction; Drugs, Chinese Herbal; Humans; Medicine, Chinese Traditional; Neuroprotective Agents; Panax notoginseng; Pyrazines; Saponins

2020

Trials

5 trial(s) available for 3-n-butylphthalide and Cerebral Infarction

ArticleYear
The effect of edaravone combined with DL-3-N-butylphthalide on the levels of tumor necrosis factor-alpha, interleukin-10, neuron-specific enolase and effect in patients with acute cerebral infarction.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2022, Volume: 73, Issue:3

    Topics: Acute Disease; Brain Ischemia; Cerebral Infarction; Edaravone; Humans; Interleukin-10; Phosphopyruvate Hydratase; Quality of Life; Stroke; Tumor Necrosis Factor-alpha

2022
Effects of dl-3-n-butylphthalide on serum lipoprotein-associated phospholipase A2 and hypersensitive C-reactive protein levels in acute cerebral infarction.
    Brain and behavior, 2019, Volume: 9, Issue:12

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Acute Disease; Benzofurans; C-Reactive Protein; Cerebral Infarction; Drug Monitoring; Female; Humans; Male; Middle Aged; Neuroprotective Agents; Treatment Outcome

2019
The efficacy and safety of Dl-3n-butylphthalide on progressive cerebral infarction: A randomized controlled STROBE study.
    Medicine, 2017, Volume: 96, Issue:30

    Topics: Activities of Daily Living; Administration, Oral; Adult; Aged; Alanine Transaminase; Aspartate Aminotransferases; Benzofurans; Cerebral Infarction; Disability Evaluation; Disease Progression; Double-Blind Method; Female; Humans; Male; Middle Aged; Neuroprotective Agents; Severity of Illness Index; Time Factors; Treatment Outcome

2017
Effects of dl-3-n-butylphthalide on serum VEGF and bFGF levels in acute cerebral infarction.
    European review for medical and pharmacological sciences, 2017, Volume: 21, Issue:19

    Topics: Activities of Daily Living; Adult; Aged; Aged, 80 and over; Benzofurans; Cerebral Infarction; Female; Fibroblast Growth Factor 2; Humans; Male; Middle Aged; Neuroprotective Agents; Stroke; Vascular Endothelial Growth Factor A; Young Adult

2017
Clinical study of Butylphthalide combined with Xue Shuan Tong on serum inflammatory factors and prognosis effect of patients with cerebral infarction.
    Pakistan journal of pharmaceutical sciences, 2015, Volume: 28, Issue:5 Suppl

    Topics: Aged; Aged, 80 and over; Benzofurans; Calcitonin Gene-Related Peptide; Carotid Arteries; Carotid Intima-Media Thickness; Cerebral Infarction; Drugs, Chinese Herbal; Female; Humans; Inflammation; Interleukin-2; Male; Middle Aged; Nervous System Diseases; Plaque, Atherosclerotic; Prognosis

2015

Other Studies

19 other study(ies) available for 3-n-butylphthalide and Cerebral Infarction

ArticleYear
Effects of butylphthalide on the levels of serum C-reactive protein, Parkinson disease protein 7 and neurotrophin-3 and neurological function in patients with acute cerebral infarction.
    Pakistan journal of pharmaceutical sciences, 2022, Volume: 35, Issue:1(Special)

    Topics: Aged; Benzofurans; C-Reactive Protein; Cerebral Infarction; Female; Gene Expression Regulation; Humans; Male; Neuroprotective Agents; Neurotrophin 3; Protein Deglycase DJ-1

2022
Cerebral hemodynamic changes assessment by transcranial doppler ultrasound in patients with acute cerebral infarction before and after treatment with butylphthalide.
    Pakistan journal of pharmaceutical sciences, 2022, Volume: 35, Issue:2(Special)

    Topics: Acute Disease; Benzofurans; Brain Ischemia; Cerebral Infarction; Hemodynamics; Humans; Stroke; Ultrasonography, Doppler, Transcranial

2022
A combination of tetramethylpyrazine hydrochloride and butylphthalide on serum S100B, CRP, Hcy levels and NIHSS score in patients with acute cerebral infarction: A retrospective study.
    Pakistan journal of pharmaceutical sciences, 2022, Volume: 35, Issue:3(Special)

    Topics: Acute Disease; Benzofurans; Brain Ischemia; Cerebral Infarction; Humans; Pyrazines; Retrospective Studies; S100 Calcium Binding Protein beta Subunit; Stroke

2022
Effect and clinical evaluation of butylphthalide combined with ureklin on ischemic low perfusion area in patients with acute cerebral infarction.
    Minerva medica, 2023, Volume: 114, Issue:4

    Topics: Brain Ischemia; Cerebral Infarction; Humans; Perfusion; Stroke

2023
Effectiveness of alteplase intravenous thrombolysis combined with butylphthalide in patients with acute severe cerebral infarction.
    Folia neuropathologica, 2022, Volume: 60, Issue:4

    Topics: Brain Ischemia; Cerebral Infarction; Fibrinolytic Agents; Humans; Quality of Life; Stroke; Thrombolytic Therapy; Tissue Plasminogen Activator; Treatment Outcome

2022
DL-3-n-butylphthalide Attenuates Cerebral Ischemia-Reperfusion Injury by Inhibiting Mitochondrial Omi/HtrA2-Mediated Apoptosis.
    Current neurovascular research, 2023, Volume: 20, Issue:1

    Topics: Animals; Apoptosis; Cerebral Infarction; High-Temperature Requirement A Serine Peptidase 2; Ischemic Stroke; Male; Mitochondria; Mitochondrial Proteins; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Reperfusion Injury

2023
Butylphthalide regulation of nerve cells in rats with cerebral infarction through jnk/p38mapk signaling pathway15.
    Pakistan journal of pharmaceutical sciences, 2023, Volume: 36, Issue:2(Special)

    Topics: Animals; Cerebral Infarction; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Signaling System; Neurons; Neuroprotective Agents; Peanut Oil; Rats

2023
Butylphthalide regulation of nerve cells in rats with cerebral infarction through jnk/p38mapk signaling pathway.
    Pakistan journal of pharmaceutical sciences, 2023, Volume: 36, Issue:4(Special)

    Topics: Animals; Cerebral Infarction; Male; MAP Kinase Signaling System; Neurons; Peanut Oil; Rats

2023
The effect of butylphthalide on improving the neurological function of patients with acute anterior circulation cerebral infarction after mechanical thrombectomy.
    Medicine, 2023, Aug-25, Volume: 102, Issue:34

    Topics: Acute Disease; Brain Ischemia; Cerebral Infarction; Humans; Retrospective Studies; Stroke; Thrombectomy; United States

2023
Influence of butyphthalide combined with urinary kallikrein in ACI treatment on neuro-cytokines and vascular endothelial function and its clinical effect.
    The International journal of neuroscience, 2021, Volume: 131, Issue:1

    Topics: Adult; Aged; Benzofurans; Cerebral Infarction; Cytokines; Drug Therapy, Combination; Female; Humans; Infusions, Intravenous; Kallikreins; Male; Middle Aged; Phosphopyruvate Hydratase; Treatment Outcome

2021
Use of l-3-n-Butylphthalide within 24 h after intravenous thrombolysis for acute cerebral infarction.
    Complementary therapies in medicine, 2020, Volume: 52

    Topics: Administration, Intravenous; Adult; Aged; Aged, 80 and over; Benzofurans; Capsules; Cerebral Infarction; Female; Humans; Male; Middle Aged; Thrombolytic Therapy; Time Factors; Tissue Plasminogen Activator

2020
Acute bilateral cerebral infarction in the presence of neuromyelitis optica spectrum disorder: A case report.
    Medicine, 2020, Oct-02, Volume: 99, Issue:40

    Topics: Acute Disease; Administration, Intravenous; Administration, Oral; Anticholesteremic Agents; Aphasia, Broca; Aspirin; Atorvastatin; Benzofurans; Cerebral Infarction; Female; Humans; Magnetic Resonance Imaging; Methylprednisolone; Middle Aged; Neuromyelitis Optica; Neuroprotective Agents; Plasmapheresis; Platelet Aggregation Inhibitors; Treatment Outcome

2020
Fuzzy
    Contrast media & molecular imaging, 2021, Volume: 2021

    Topics: Algorithms; Benzofurans; Biomarkers; Cerebral Infarction; Drug Therapy, Combination; Edaravone; Endothelium, Vascular; Female; Follow-Up Studies; Fuzzy Logic; Humans; Image Interpretation, Computer-Assisted; Magnetic Resonance Imaging; Male; Middle Aged; Neuroprotective Agents; Prognosis

2021
Dl-3-n-butylphthalide protects the blood brain barrier of cerebral infarction by activating the Nrf-2/HO-1 signaling pathway in mice.
    European review for medical and pharmacological sciences, 2018, Volume: 22, Issue:7

    Topics: Animals; Benzofurans; Blood-Brain Barrier; Brain; Cerebral Infarction; Heme Oxygenase-1; Male; Membrane Proteins; Mice; Neuroprotective Agents; NF-E2-Related Factor 2; Rats, Sprague-Dawley; Signal Transduction

2018
3-N-butylphthalide inhibits neuronal apoptosis in rats with cerebral infarction via targeting P38/MAPK.
    European review for medical and pharmacological sciences, 2019, Volume: 23, Issue:3 Suppl

    Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Benzofurans; Cerebral Infarction; Disease Models, Animal; Down-Regulation; Female; Gene Expression Regulation; Injections, Intraperitoneal; MAP Kinase Signaling System; Neurons; Neuroprotective Agents; Proto-Oncogene Proteins c-bcl-2; Rats

2019
The effect of butylphthalide on the brain edema, blood-brain barrier of rats after focal cerebral infarction and the expression of Rho A.
    Cell biochemistry and biophysics, 2014, Volume: 69, Issue:2

    Topics: Animals; Benzofurans; Blood-Brain Barrier; Brain; Brain Edema; Cerebral Cortex; Cerebral Infarction; Disease Models, Animal; Immunohistochemistry; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; rhoA GTP-Binding Protein; Time Factors; Water

2014
[Effect of 3-n-butylphthalide pretreatment on expression of the HSP70 after brain ischemia/reperfusion].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2015, Volume: 31, Issue:2

    Topics: Animals; Benzofurans; CA1 Region, Hippocampal; Cell Death; Cerebral Infarction; HSP70 Heat-Shock Proteins; Ischemic Preconditioning; Neurons; Rats; Rats, Wistar; Reperfusion Injury

2015
Impacts of N-Butylphthalide on expression of growth factors in rats with focal cerebral ischemia.
    Bosnian journal of basic medical sciences, 2016, Jan-01, Volume: 16, Issue:2

    Topics: Animals; Behavior, Animal; Benzofurans; Brain Ischemia; Cerebral Infarction; Intercellular Signaling Peptides and Proteins; Male; Neurologic Examination; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Reperfusion Injury; RNA, Messenger; Transforming Growth Factor beta1; Vascular Endothelial Growth Factor A

2016
[Protective effect of dl-3-n-butylphthalide on ischemic neurological damage and abnormal behavior in rats subjected to focal ischemia].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1995, Volume: 30, Issue:12

    Topics: Animals; Behavior, Animal; Benzofurans; Cerebral Infarction; Dizocilpine Maleate; Male; Neuroprotective Agents; Nimodipine; Rats; Rats, Wistar; Vasodilator Agents

1995