3-n-butylphthalide has been researched along with Cerebral Infarction in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (3.85) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 9 (34.62) | 24.3611 |
| 2020's | 16 (61.54) | 2.80 |
| Authors | Studies |
|---|---|
| Che, F; Dong, X; Feng, L; Jing, R; Pei, Q; Qian, J; Ren, G; Xue, L | 1 |
| Guo, Y; Hu, H; Liu, H; Liu, Y; Xu, G; Yan, J | 1 |
| Fu, B; Gao, G; Meng, S | 1 |
| Zhu, C | 1 |
| Shen, QQ; Tong, XW; Wang, W; Wu, H | 1 |
| Che, J; Wang, Z | 1 |
| Abuduxukuer, R; Guo, ZN; He, Q; Huang, S; Qu, Y; Ren, J; Sun, X; Yang, Y; Zhang, K | 1 |
| Liu, X; Ma, Y; Wang, Y; Zhang, Q | 1 |
| Guo, J; Guo, W; Xing, Y | 2 |
| Luan, X; Wang, X; Yang, Z | 1 |
| Dong, YT; Hu, FY; Li, TT; Liu, Y; Zhang, XL; Zhang, Y | 1 |
| Chen, G; Deng, Y; Jiang, W; Li, X; Shangguan, S; Zhou, F; Zou, W | 1 |
| Liu, JX; Ren, JG; Wang, M; Yao, MJ | 1 |
| Feng, Y; Gao, P; Gui, L; Pan, W; Qin, B; Sima, D; Wang, J; Wang, M; Wang, Q; Yuan, Y | 1 |
| Gao, YL; Guo, JJ; Wang, M; Wang, ZY; Yu, XF | 1 |
| Chang, H; Li, H; Wang, D; Yin, A; Yin, J | 1 |
| Feng, S; Gu, F; Hu, L; Mao, S; Zang, Y; Zhang, C; Zhao, S | 1 |
| Fan, XH; Li, K; Luo, CJ; Ning, LP; Tang, SC; Xue, P; Zhang, KH | 1 |
| Ma, QS; Ma, YB; Mi, LX; Nai, Y; Song, DJ; Zhang, LH; Zhao, YJ | 1 |
| Cheng, W; Dong, LF; Liao, W; Zhong, Y | 1 |
| Gao, P; Hu, J; Li, B; Wen, Q; Wu, Y | 1 |
| Guo, L; Niu, LJ; Qi, FM; Zhou, Y | 1 |
| Du, R; Shi, ZB; Teng, JF; Wang, Y; Zhao, XY | 1 |
| Jiang, Y; Sun, L; Wang, J; Xuan, X | 1 |
| Feng, YP; Liu, XG | 1 |
2 review(s) available for 3-n-butylphthalide and Cerebral Infarction
| Article | Year |
|---|---|
Effects of NBP injection on the inflammatory response, oxidative stress response and vascular endothelial function in patients with ACI: A systematic review and meta-analysis.
Topics: Cerebral Infarction; Drugs, Chinese Herbal; Humans; Retrospective Studies; Stroke; Vascular Endothelial Growth Factor A | 2023 |
[Advances in research on pharmacological and neuroprotective effects of traditional Chinese medicine after cerebral ischemia].
Topics: Benzofurans; Brain Ischemia; Cerebral Infarction; Drugs, Chinese Herbal; Humans; Medicine, Chinese Traditional; Neuroprotective Agents; Panax notoginseng; Pyrazines; Saponins | 2020 |
5 trial(s) available for 3-n-butylphthalide and Cerebral Infarction
| Article | Year |
|---|---|
The effect of edaravone combined with DL-3-N-butylphthalide on the levels of tumor necrosis factor-alpha, interleukin-10, neuron-specific enolase and effect in patients with acute cerebral infarction.
Topics: Acute Disease; Brain Ischemia; Cerebral Infarction; Edaravone; Humans; Interleukin-10; Phosphopyruvate Hydratase; Quality of Life; Stroke; Tumor Necrosis Factor-alpha | 2022 |
Effects of dl-3-n-butylphthalide on serum lipoprotein-associated phospholipase A2 and hypersensitive C-reactive protein levels in acute cerebral infarction.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Acute Disease; Benzofurans; C-Reactive Protein; Cerebral Infarction; Drug Monitoring; Female; Humans; Male; Middle Aged; Neuroprotective Agents; Treatment Outcome | 2019 |
The efficacy and safety of Dl-3n-butylphthalide on progressive cerebral infarction: A randomized controlled STROBE study.
Topics: Activities of Daily Living; Administration, Oral; Adult; Aged; Alanine Transaminase; Aspartate Aminotransferases; Benzofurans; Cerebral Infarction; Disability Evaluation; Disease Progression; Double-Blind Method; Female; Humans; Male; Middle Aged; Neuroprotective Agents; Severity of Illness Index; Time Factors; Treatment Outcome | 2017 |
Effects of dl-3-n-butylphthalide on serum VEGF and bFGF levels in acute cerebral infarction.
Topics: Activities of Daily Living; Adult; Aged; Aged, 80 and over; Benzofurans; Cerebral Infarction; Female; Fibroblast Growth Factor 2; Humans; Male; Middle Aged; Neuroprotective Agents; Stroke; Vascular Endothelial Growth Factor A; Young Adult | 2017 |
Clinical study of Butylphthalide combined with Xue Shuan Tong on serum inflammatory factors and prognosis effect of patients with cerebral infarction.
Topics: Aged; Aged, 80 and over; Benzofurans; Calcitonin Gene-Related Peptide; Carotid Arteries; Carotid Intima-Media Thickness; Cerebral Infarction; Drugs, Chinese Herbal; Female; Humans; Inflammation; Interleukin-2; Male; Middle Aged; Nervous System Diseases; Plaque, Atherosclerotic; Prognosis | 2015 |
19 other study(ies) available for 3-n-butylphthalide and Cerebral Infarction
| Article | Year |
|---|---|
Effects of butylphthalide on the levels of serum C-reactive protein, Parkinson disease protein 7 and neurotrophin-3 and neurological function in patients with acute cerebral infarction.
Topics: Aged; Benzofurans; C-Reactive Protein; Cerebral Infarction; Female; Gene Expression Regulation; Humans; Male; Neuroprotective Agents; Neurotrophin 3; Protein Deglycase DJ-1 | 2022 |
Cerebral hemodynamic changes assessment by transcranial doppler ultrasound in patients with acute cerebral infarction before and after treatment with butylphthalide.
Topics: Acute Disease; Benzofurans; Brain Ischemia; Cerebral Infarction; Hemodynamics; Humans; Stroke; Ultrasonography, Doppler, Transcranial | 2022 |
A combination of tetramethylpyrazine hydrochloride and butylphthalide on serum S100B, CRP, Hcy levels and NIHSS score in patients with acute cerebral infarction: A retrospective study.
Topics: Acute Disease; Benzofurans; Brain Ischemia; Cerebral Infarction; Humans; Pyrazines; Retrospective Studies; S100 Calcium Binding Protein beta Subunit; Stroke | 2022 |
Effect and clinical evaluation of butylphthalide combined with ureklin on ischemic low perfusion area in patients with acute cerebral infarction.
Topics: Brain Ischemia; Cerebral Infarction; Humans; Perfusion; Stroke | 2023 |
Effectiveness of alteplase intravenous thrombolysis combined with butylphthalide in patients with acute severe cerebral infarction.
Topics: Brain Ischemia; Cerebral Infarction; Fibrinolytic Agents; Humans; Quality of Life; Stroke; Thrombolytic Therapy; Tissue Plasminogen Activator; Treatment Outcome | 2022 |
DL-3-n-butylphthalide Attenuates Cerebral Ischemia-Reperfusion Injury by Inhibiting Mitochondrial Omi/HtrA2-Mediated Apoptosis.
Topics: Animals; Apoptosis; Cerebral Infarction; High-Temperature Requirement A Serine Peptidase 2; Ischemic Stroke; Male; Mitochondria; Mitochondrial Proteins; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2023 |
Butylphthalide regulation of nerve cells in rats with cerebral infarction through jnk/p38mapk signaling pathway15.
Topics: Animals; Cerebral Infarction; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Signaling System; Neurons; Neuroprotective Agents; Peanut Oil; Rats | 2023 |
Butylphthalide regulation of nerve cells in rats with cerebral infarction through jnk/p38mapk signaling pathway.
Topics: Animals; Cerebral Infarction; Male; MAP Kinase Signaling System; Neurons; Peanut Oil; Rats | 2023 |
The effect of butylphthalide on improving the neurological function of patients with acute anterior circulation cerebral infarction after mechanical thrombectomy.
Topics: Acute Disease; Brain Ischemia; Cerebral Infarction; Humans; Retrospective Studies; Stroke; Thrombectomy; United States | 2023 |
Influence of butyphthalide combined with urinary kallikrein in ACI treatment on neuro-cytokines and vascular endothelial function and its clinical effect.
Topics: Adult; Aged; Benzofurans; Cerebral Infarction; Cytokines; Drug Therapy, Combination; Female; Humans; Infusions, Intravenous; Kallikreins; Male; Middle Aged; Phosphopyruvate Hydratase; Treatment Outcome | 2021 |
Use of l-3-n-Butylphthalide within 24 h after intravenous thrombolysis for acute cerebral infarction.
Topics: Administration, Intravenous; Adult; Aged; Aged, 80 and over; Benzofurans; Capsules; Cerebral Infarction; Female; Humans; Male; Middle Aged; Thrombolytic Therapy; Time Factors; Tissue Plasminogen Activator | 2020 |
Acute bilateral cerebral infarction in the presence of neuromyelitis optica spectrum disorder: A case report.
Topics: Acute Disease; Administration, Intravenous; Administration, Oral; Anticholesteremic Agents; Aphasia, Broca; Aspirin; Atorvastatin; Benzofurans; Cerebral Infarction; Female; Humans; Magnetic Resonance Imaging; Methylprednisolone; Middle Aged; Neuromyelitis Optica; Neuroprotective Agents; Plasmapheresis; Platelet Aggregation Inhibitors; Treatment Outcome | 2020 |
Fuzzy
Topics: Algorithms; Benzofurans; Biomarkers; Cerebral Infarction; Drug Therapy, Combination; Edaravone; Endothelium, Vascular; Female; Follow-Up Studies; Fuzzy Logic; Humans; Image Interpretation, Computer-Assisted; Magnetic Resonance Imaging; Male; Middle Aged; Neuroprotective Agents; Prognosis | 2021 |
Dl-3-n-butylphthalide protects the blood brain barrier of cerebral infarction by activating the Nrf-2/HO-1 signaling pathway in mice.
Topics: Animals; Benzofurans; Blood-Brain Barrier; Brain; Cerebral Infarction; Heme Oxygenase-1; Male; Membrane Proteins; Mice; Neuroprotective Agents; NF-E2-Related Factor 2; Rats, Sprague-Dawley; Signal Transduction | 2018 |
3-N-butylphthalide inhibits neuronal apoptosis in rats with cerebral infarction via targeting P38/MAPK.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Benzofurans; Cerebral Infarction; Disease Models, Animal; Down-Regulation; Female; Gene Expression Regulation; Injections, Intraperitoneal; MAP Kinase Signaling System; Neurons; Neuroprotective Agents; Proto-Oncogene Proteins c-bcl-2; Rats | 2019 |
The effect of butylphthalide on the brain edema, blood-brain barrier of rats after focal cerebral infarction and the expression of Rho A.
Topics: Animals; Benzofurans; Blood-Brain Barrier; Brain; Brain Edema; Cerebral Cortex; Cerebral Infarction; Disease Models, Animal; Immunohistochemistry; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; rhoA GTP-Binding Protein; Time Factors; Water | 2014 |
[Effect of 3-n-butylphthalide pretreatment on expression of the HSP70 after brain ischemia/reperfusion].
Topics: Animals; Benzofurans; CA1 Region, Hippocampal; Cell Death; Cerebral Infarction; HSP70 Heat-Shock Proteins; Ischemic Preconditioning; Neurons; Rats; Rats, Wistar; Reperfusion Injury | 2015 |
Impacts of N-Butylphthalide on expression of growth factors in rats with focal cerebral ischemia.
Topics: Animals; Behavior, Animal; Benzofurans; Brain Ischemia; Cerebral Infarction; Intercellular Signaling Peptides and Proteins; Male; Neurologic Examination; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Reperfusion Injury; RNA, Messenger; Transforming Growth Factor beta1; Vascular Endothelial Growth Factor A | 2016 |
[Protective effect of dl-3-n-butylphthalide on ischemic neurological damage and abnormal behavior in rats subjected to focal ischemia].
Topics: Animals; Behavior, Animal; Benzofurans; Cerebral Infarction; Dizocilpine Maleate; Male; Neuroprotective Agents; Nimodipine; Rats; Rats, Wistar; Vasodilator Agents | 1995 |