Page last updated: 2024-10-21

3-methylcholanthrene and Stomach Neoplasms

3-methylcholanthrene has been researched along with Stomach Neoplasms in 53 studies

Methylcholanthrene: A carcinogen that is often used in experimental cancer studies.
3-methylcholanthrene : A pentacyclic ortho- and peri-fused polycyclic arene consisting of a dihydrocyclopenta[ij]tetraphene ring system with a methyl substituent at the 3-position.

Stomach Neoplasms: Tumors or cancer of the STOMACH.

Research Excerpts

ExcerptRelevanceReference
" Here we have examined human gastric/esophageal adenocarcinoma cell lines for p53 mutational status, chemosensitivity to 5-fluorouracil, mitomycin C, and cis-dichlorodiammineplatinum(II), alteration in p53 levels following exposure of cells to these drugs, and the mechanisms involved in regulating p53 levels."3.69The mutational status of p53 protein in gastric and esophageal adenocarcinoma cell lines predicts sensitivity to chemotherapeutic agents. ( Albino, AP; Altorki, NK; Blundell, ML; de Oliveira, AR; Kelsen, DP; Lai, L; Loganzo, F; Maslak, P; Nabeya, Y; Schwartz, GK, 1995)

Research

Studies (53)

TimeframeStudies, this research(%)All Research%
pre-199048 (90.57)18.7374
1990's3 (5.66)18.2507
2000's1 (1.89)29.6817
2010's1 (1.89)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hong, W1
Guo, F1
Yang, M1
Xu, D1
Zhuang, Z1
Niu, B1
Bai, Q1
Li, X1
MORI, K1
ICHII, S1
SHIGETA, Y1
MURAKAMI, T1
MATSUDA, H1
OTSUKA, K1
STEWART, HL5
SNELL, KC2
ZALDIVAR, RS2
ALIAGA, C1
RODRIGUEZ, H1
OJIMA, Y1
KANAZAWA, K1
KIKUCHI, K1
TSUJI, Y1
ITAKURA, K1
KATAGIRI, H1
YABE, Y1
WARREN, IA1
BERK, JE1
KOBERNICK, SD1
MORRIS, HP1
HITCHCOCK, CR2
FIRMINGER, HI1
HARE, WV1
BENNETT, JG1
LORENZ, E1
Dhiman, M1
Mendiz, E1
Rao, AR1
Kale, RK1
Utsumi, Y1
Niwa, H1
Kaneko, E1
Umeda, N1
Miwa, T1
Feit, J1
Svejda, J1
Sochorová, M1
Arkhipov, GN6
Wang, XH1
Zhang, XY1
Chen, XT1
Randeria, JD1
Wieman, TJ1
Max, MH1
Voyles, CR1
Barrows, GH1
Nabeya, Y1
Loganzo, F1
Maslak, P1
Lai, L1
de Oliveira, AR1
Schwartz, GK1
Blundell, ML1
Altorki, NK1
Kelsen, DP1
Albino, AP1
Matsuda, A1
Yoshioka, O1
Yamashita, T1
Ebihara, K1
Umezawa, H1
Miura, T1
Katayama, K1
Yokoyama, M1
Nagai, S1
Ito, N1
Tatematsu, M1
Brodsky, LH1
Feinberg, RF1
Sorof, S1
Homburger, F3
Handler, AH1
Soto, E1
Hsueh, SS2
Van Dongen, CG1
Russfield, AB1
Watanabe, H1
Suda, Y1
Hara, E1
Tagashira, Y1
Shimamura, K1
Vol'fson, NI1
Kalinovskiĭ, VP1
Pliss, GB1
Tereshchenko, IP1
Kashulina, AP1
Aleksandrova, LM2
Golovanov, MV1
Roe, FJ1
Walters, MA1
Akamatsu, Y1
Barton, BP1
Kowalewski, K1
Kasper, T1
Yamakawa, T2
Von Hofe, E1
Kagan, R1
Morgenstern, L3
Zaldívar, R1
Patin, CS1
Beloshapko, AA1
Kerr, CS1
Krüger, G1
Ritter, K1
Walburg, HE1
Cosgrove, GE1
Ito, Y1
Fisher, JC1
Hammond, WG1
Ackerman, NB1
Laurén, P1
Holmberg, B1

Reviews

2 reviews available for 3-methylcholanthrene and Stomach Neoplasms

ArticleYear
[Some contributions by chemical carcinogenesis--what is the animal model of human cancer? (author's transl)].
    Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 1978, Volume: 23, Issue:6

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Cricetinae; Disease Models, Animal; Dogs;

1978
[Dynamics of morphological and biochemical changes in the gastric mucosa in rats during tumor induction].
    Voprosy onkologii, 1990, Volume: 36, Issue:11

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Gastric Mucosa; Methylcholanthrene; Methylnitronitrosogua

1990

Trials

1 trial available for 3-methylcholanthrene and Stomach Neoplasms

ArticleYear
Fundamental and clinical studies on new bleomycin analogs.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1978, Volume: 63

    Topics: Adult; Aged; Animals; Antibiotics, Antineoplastic; Bleomycin; Carcinoma, Squamous Cell; Clinical Tri

1978

Other Studies

50 other studies available for 3-methylcholanthrene and Stomach Neoplasms

ArticleYear
Hydroxysteroid sulfotransferase 2B1 affects gastric epithelial function and carcinogenesis induced by a carcinogenic agent.
    Lipids in health and disease, 2019, Nov-22, Volume: 18, Issue:1

    Topics: Animals; Base Sequence; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Cholesterol; CRISPR-Ca

2019
Further studies on the gastric lesions of rats by oral administration of methylcholanthrene, with a case of colonic adenocarcinoma.
    Gan, 1955, Volume: 46, Issue:4

    Topics: Adenocarcinoma; Administration, Oral; Animals; Colonic Neoplasms; Methylcholanthrene; Neoplasms, Exp

1955
[A fundamental study for experimental induction of ulcus-carcinoma of the stomach in rat by oral administration of 20-methylcholanthrene].
    Gan, 1957, Volume: 48, Issue:4

    Topics: Administration, Oral; Animals; Carcinoma; Methylcholanthrene; Neoplasms, Experimental; Rats; Stomach

1957
Histopathogenesis of carcinoma induced in the glandular stomach of C57BL mice by the intramural injection of 20-methylcholanthrene.
    Journal of the National Cancer Institute, 1958, Volume: 21, Issue:5

    Topics: Animals; Carcinoma; Injections; Methylcholanthrene; Mice; Mice, Inbred C57BL; Neoplasms, Experimenta

1958
Epithelial lesions of the stomach induced in guinea pigs by intramural implantation of 3-methylcholanthrene.
    Zeitschrift fur Krebsforschung, 1962, Volume: 65

    Topics: Animals; Diverticulum, Stomach; Guinea Pigs; Leiomyosarcoma; Methylcholanthrene; Neoplasms; Sarcoma;

1962
Cancer research in Chile.
    Nature, 1962, Nov-10, Volume: 196

    Topics: Antineoplastic Agents; Chile; Hexestrol; Lung Neoplasms; Mechlorethamine; Methylcholanthrene; Neopla

1962
EXPERIMENTAL STUDIES ON THE INFLUENCE OF RETICULO-ENDOTHELIAL SYSTEM UPON THE INDUCTION OF MALIGNANT GASTRIC NEOPLASMS.
    Nihon geka hokan. Archiv fur japanische Chirurgie, 1963, Jul-01, Volume: 32

    Topics: Adenocarcinoma; Alcohols; Ethanol; Methylcholanthrene; Mononuclear Phagocyte System; Neoplasms; Neop

1963
[STUDIES ON EXPERIMENTAL CANCER IN THE STOMACH GLANDS OF RATS, WITH SPECIAL REFERENCE TO LOCAL CHANGES CAUSED BY THE SUBMUCOSAL INSERTION IN THE STOMACH WALL OF 20-METHYLCHOLANTHRENE AND SUBCUTANEOUS INJECTION OF 4-NITRO-QUINOLINE N-OXIDE].
    Tokyo igaku zasshi. The Tokyo journal of medical sciences, 1964, Volume: 72

    Topics: Adenocarcinoma; Antineoplastic Agents; Gastric Mucosa; Injections, Subcutaneous; Methylcholanthrene;

1964
A CASE OF METASTASES OF GASTRIC CANCER TO HYPERNEPHROMA AND ITS METASTATIC FOCI.
    Acta pathologica japonica, 1964, Volume: 14

    Topics: Adenocarcinoma; Carcinoma, Hepatocellular; Carcinoma, Renal Cell; Kidney Neoplasms; Liver Neoplasms;

1964
TETRACYCLINE FLUORESCENCE IN MOUSE GASTRIC CARCINOMA.
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 1964, Volume: 12

    Topics: Animals; Bone and Bones; Cytoplasm; Fluorescence; Gastric Mucosa; Histocytochemistry; Liver; Methylc

1964
(THE COMBINED EFFECT OF 3-METHYLCHOLANTHRENE AND N,N'-2,7-FLUORENYLENEBISACETMIDE ON THE INDUCTION OF CANCER OF THE GLANDULAR STOMACH OF THE RAT.)
    Journal of the National Cancer Institute, 1965, Volume: 34

    Topics: Abdominal Neoplasms; Abdominal Wall; Atrophy; Carcinogens; Ethmoid Bone; Female; Humans; Inflammatio

1965
Failure of bile as abetting agent for 20-methylcholanthrene in induction of gastric tumors in mice.
    Journal of the National Cancer Institute, 1951, Volume: 12, Issue:2

    Topics: Animals; Bile; Methylcholanthrene; Mice; Stomach Neoplasms

1951
Histopathogenesis of squamous-cell carcinoma induced in the forestomach of mice by intramural injection of 20-methylcholanthrene.
    Journal of the National Cancer Institute, 1951, Volume: 12, Issue:3

    Topics: Animals; Carcinoma; Carcinoma, Squamous Cell; Methylcholanthrene; Mice; Stomach Neoplasms

1951
Failure of eugenol and heat to potentiate gastric tumor induction by 20-methylcholanthrene in mice.
    Journal of the National Cancer Institute, 1952, Volume: 12, Issue:4

    Topics: Animals; Eugenol; Hot Temperature; Methylcholanthrene; Mice; Stomach Neoplasms

1952
Tumors of the glandular stomach induced in rats by intramural injection of 20-methylcholanthrene.
    Journal of the National Cancer Institute, 1952, Volume: 12, Issue:5

    Topics: Animals; Injections; Methylcholanthrene; Neoplasms; Rats; Stomach Neoplasms

1952
Chemopreventive effects of mustard (Brassica compestris) on chemically induced tumorigenesis in murine forestomach and uterine cervix.
    Human & experimental toxicology, 2005, Volume: 24, Issue:6

    Topics: Administration, Oral; Animals; Benzo(a)pyrene; Brassica; Catalase; Diet; Dose-Response Relationship,

2005
[Experimental trials of induction of chronic ulcer and cancer in the stomach].
    Gan no rinsho. Japan journal of cancer clinics, 1966, Volume: 12, Issue:12

    Topics: Animals; Chronic Disease; Methylcholanthrene; Neoplasms, Experimental; Rats; Stomach Neoplasms; Stom

1966
Experimental intestinal metaplasia of gastric mucosa of rats and its relationship to carcinoma.
    Neoplasma, 1967, Volume: 14, Issue:3

    Topics: Adenocarcinoma; Animals; Metaplasia; Methylcholanthrene; Neoplasms, Radiation-Induced; Phosphorus Is

1967
Induction of cancer of the glandular stomach in rats by 20-methylcholanthrene.
    International journal of cancer, 1967, Sep-15, Volume: 2, Issue:5

    Topics: Adenocarcinoma; Animals; Ephedrine; Methylcholanthrene; Neoplasm Metastasis; Neoplasms, Experimental

1967
Ascorbic acid inhibition of 3-methylcholanthrene induced carcinoma of glandular stomach in mice.
    Chinese medical journal, 1984, Volume: 97, Issue:3

    Topics: Animals; Ascorbic Acid; Immunity, Cellular; Immunocompetence; Leukocyte Count; Male; Methylcholanthr

1984
Carcinoids and adenocarcinoma of the glandular stomach in Praomys (Mastomys) natalensis treated with 3-methylcholanthrene.
    Gan, 1980, Volume: 71, Issue:2

    Topics: Adenocarcinoma; Animals; Carcinoid Tumor; Methylcholanthrene; Mice; Neoplasms, Experimental; Stomach

1980
Diversion of duodenal contents: its effect on the production of experimental gastric cancer.
    Archives of surgery (Chicago, Ill. : 1960), 1980, Volume: 115, Issue:8

    Topics: Adenocarcinoma; Animals; Duodenum; Gastric Mucosa; Gastroenterostomy; Male; Metaplasia; Methylcholan

1980
The mutational status of p53 protein in gastric and esophageal adenocarcinoma cell lines predicts sensitivity to chemotherapeutic agents.
    International journal of cancer, 1995, Feb-20, Volume: 64, Issue:1

    Topics: Adenocarcinoma; Antineoplastic Agents; Cell Cycle; Cell Line; Cisplatin; DNA Damage; Esophageal Neop

1995
Carcinogen-protein complexes in hamster colon and glandular stomach during long-term administration of 3-methylcholanthrene.
    Cancer research, 1978, Volume: 38, Issue:6

    Topics: Animals; Colon; Colonic Neoplasms; Cricetinae; Cytosol; Gastric Mucosa; In Vitro Techniques; Male; M

1978
Adenocarcinoma of the glandular stomach following 3-methylcholanthrene, N-nitrosodiethylamine, or N-nitrosodimethylamine feeding in carcinogen-susceptible inbred Syrian.
    Journal of the National Cancer Institute, 1976, Volume: 57, Issue:1

    Topics: Adenocarcinoma; Animals; Cricetinae; Diethylnitrosamine; Dimethylnitrosamine; Female; Male; Mesocric

1976
[The secretory function of the stomach in pre-tumorous conditions and tumors].
    Voprosy onkologii, 1975, Volume: 21, Issue:6

    Topics: Animals; Gastric Juice; Gastric Mucosa; Male; Methylcholanthrene; Neoplasms, Experimental; Precancer

1975
[Immunohistochemical Study of 3-methylcholanthrene inducible cytochrome P-450 in the stomach and liver--a guide of postoperative chemotherapy in gastric cancer].
    Rinsho byori. The Japanese journal of clinical pathology, 1991, Volume: 39, Issue:4

    Topics: Animals; Combined Modality Therapy; Cytochrome P-450 Enzyme System; Enzyme Induction; Humans; Immuno

1991
[New methodologic approach to evaluating the functional state of neutrophils].
    Laboratornoe delo, 1986, Issue:2

    Topics: Animals; Humans; Male; Methylcholanthrene; Neoplasms; Neoplasms, Experimental; Neutrophils; Rats; Ra

1986
[Surface condition of erythrocytes in the dynamics of the tumor process].
    Voprosy onkologii, 1986, Volume: 32, Issue:3

    Topics: Animals; Erythrocyte Membrane; Erythrocytes, Abnormal; Glycoproteins; Histocytochemistry; Humans; Me

1986
Models of human disease in inbred Syrian hamsters.
    Health laboratory science, 1972, Volume: 9, Issue:2

    Topics: Adenocarcinoma; Animals; Benz(a)Anthracenes; Benzopyrenes; Bronchial Neoplasms; Cricetinae; Disease

1972
Sensitivity of newborn mice to carcinogenic agents.
    Food and cosmetics toxicology, 1968, Volume: 6, Issue:5

    Topics: Adenocarcinoma; Adenoma; Animals; Animals, Newborn; Benz(a)Anthracenes; Carcinogens; Carcinoma, Hepa

1968
Neoplasms and amyloidosis in strains of mice treated with 3-methylcholanthrene.
    Journal of the National Cancer Institute, 1974, Volume: 52, Issue:2

    Topics: Adenoma; Amyloidosis; Animals; Carcinoma, Hepatocellular; Carcinoma, Squamous Cell; Female; Liver Ne

1974
Achlorhydria, gastric mucosal atrophy and gastric neoplastic lesions in rats, mice and hamsters treated with an anticholinergic drug, propantheline bromide, and a carcinogen, 20-methylcholanthrene.
    Canadian journal of surgery. Journal canadien de chirurgie, 1967, Volume: 10, Issue:1

    Topics: Achlorhydria; Animals; Atrophy; Cricetinae; Gastric Mucosa; In Vitro Techniques; Methylcholanthrene;

1967
The use of tolonium in the diagnosis of malignant gastric lesions.
    Archives of surgery (Chicago, Ill. : 1960), 1972, Volume: 104, Issue:6

    Topics: Adenocarcinoma; Administration, Oral; Animals; Carcinosarcoma; Cicatrix; Coloring Agents; Diverticul

1972
[Experimental cancer production in the guinea pig stomach with heated and unheated fats in combination with methylcholanthrene].
    Archiv fur Hygiene und Bakteriologie, 1969, Volume: 153, Issue:3

    Topics: Animals; Autopsy; Dietary Fats; Female; Gastric Mucosa; Guinea Pigs; Histological Techniques; Hot Te

1969
[Factors determining the localization of tumors and the resistance of the rat stomach to orally administered carcinogenic hydrocarbons].
    Vestnik Akademii meditsinskikh nauk SSSR, 1972, Volume: 27, Issue:2

    Topics: Animals; Female; Gastric Juice; Mammary Neoplasms, Experimental; Methylcholanthrene; Mice; Neoplasms

1972
Small intestinal resistance to experimental gastric cancer.
    Archives of surgery (Chicago, Ill. : 1960), 1972, Volume: 105, Issue:1

    Topics: Animals; Intestinal Neoplasms; Intestine, Small; Jejunum; Methylcholanthrene; Neoplasms, Experimenta

1972
[Effect of thyroid hormones on the induction of stomach cancer in rats].
    Voprosy onkologii, 1972, Volume: 18, Issue:5

    Topics: Adenocarcinoma; Animals; Male; Methylcholanthrene; Neoplasms, Experimental; Rats; Rats, Inbred Strai

1972
Experimentally induced gastric adenocarcinomas. Maude Abbott Lecture, 1971.
    Laboratory investigation; a journal of technical methods and pathology, 1971, Volume: 25, Issue:6

    Topics: Adenocarcinoma; Aflatoxins; Animals; Anti-Bacterial Agents; Benz(a)Anthracenes; Carcinogens; Fluoren

1971
[Effect of neurotic changes on the functional state of the stomach and carcinogenesis].
    Voprosy onkologii, 1971, Volume: 17, Issue:10

    Topics: Adenocarcinoma; Animals; Carcinoma, Squamous Cell; Electric Stimulation; Gastric Juice; Gastrointest

1971
Influence of genetic factors on the induction of mammary and intestinal adenocarcinomas in inbred Syrian golden hamsters.
    Nature: New biology, 1971, Nov-03, Volume: 234, Issue:44

    Topics: Adenocarcinoma; Animals; Cricetinae; Female; Inbreeding; Intestinal Neoplasms; Male; Mammary Neoplas

1971
[Morphologic behavior of a fibrosarcoma following transplantation into various organs].
    Osterreichische Zeitschrift fur Erforschung und Bekampfung der Krebskrankheit, 1970, Volume: 25, Issue:3

    Topics: Animals; Cell Transformation, Neoplastic; Female; Fibrosarcoma; Glioma; Kidney Neoplasms; Liver Neop

1970
Methylcholanthrene-induced neoplasms in germ-free RFM mice.
    International journal of cancer, 1971, Sep-15, Volume: 8, Issue:2

    Topics: Administration, Oral; Animals; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Croton Oil

1971
Induction of cancer by 20-methylcholanthrene in different regions of the rat stomach.
    Cancer research, 1970, Volume: 30, Issue:11

    Topics: Adenocarcinoma; Animals; Carcinoma, Squamous Cell; Cardia; Gastric Mucosa; Male; Methods; Methylchol

1970
Induction of cutaneous nodules in rabbits with crude nucleic acid preparations from tissues of human gastric carcinomas.
    Oncology, 1967, Volume: 21, Issue:2

    Topics: Animals; DNA, Neoplasm; Female; Humans; Male; Methylcholanthrene; Microscopy, Electron; Neoplasm Tra

1967
Parabiotic transfer of tumor-specific immunity.
    Cancer, 1968, Volume: 21, Issue:1

    Topics: Adenocarcinoma; Animals; Female; Immunity, Maternally-Acquired; Methylcholanthrene; Mice; Neoplasms,

1968
Vagotomy, gastroenterostomy and experimental gastic cancer.
    Archives of surgery (Chicago, Ill. : 1960), 1968, Volume: 96, Issue:6

    Topics: Adenocarcinoma; Animals; Carcinoma, Squamous Cell; Gastroenterostomy; Hydrochloric Acid; Methylchola

1968
[Modeling glandular cancer in rats].
    Biulleten' eksperimental'noi biologii i meditsiny, 1968, Volume: 65, Issue:2

    Topics: Adenocarcinoma; Animals; Gastric Mucosa; Male; Methods; Methylcholanthrene; Neoplasms, Experimental;

1968
Development of gastric cancer in experimental animals.
    Surgical forum, 1966, Volume: 17

    Topics: Animals; Female; Gastrectomy; Hydrochloric Acid; Methylcholanthrene; Rats; Stomach Neoplasms

1966
Experimental chronic gastric ulcer in the rat. II. Epithelial changes in the margin of the ulcer.
    Annales medicinae experimentalis et biologiae Fenniae, 1966, Volume: 44, Issue:1

    Topics: Animals; Gastric Mucosa; Histocytochemistry; Methylcholanthrene; Neoplasms, Experimental; Rats; Stom

1966