3-methylcholanthrene has been researched along with Sarcoma, Epithelioid in 148 studies
Methylcholanthrene: A carcinogen that is often used in experimental cancer studies.
3-methylcholanthrene : A pentacyclic ortho- and peri-fused polycyclic arene consisting of a dihydrocyclopenta[ij]tetraphene ring system with a methyl substituent at the 3-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Using 3-methylcholanthrene-induced primary mouse tumors, we examined the distinct regulation of Treg-mediated immunosuppression between carcinomas and sarcomas." | 7.76 | 3-Methylcholanthrene-induced transforming growth factor-beta-producing carcinomas, but not sarcomas, are refractory to regulatory T cell-depletion therapy. ( Chamoto, K; Kitamura, H; Matsushima, K; Nishimura, T; Ohkuri, T; Uchinami, Y; Wakita, D, 2010) |
| "Tumor-specific transplantation antigens (TSTA), which were partially purified by preparative isoelectric focusing of 3-M KCl extracts of a fibrosarcoma MCA-F induced in inbred female C3H/HeJ mice with 3-methylcholanthrene and previously shown to display immunotherapeutic activity against subcutaneous neoplasms, were effective against pulmonary metastases." | 7.66 | Immunotherapeutic effects of partially purified tumor-specific transplantation antigens on pulmonary metastases of a 3-methylcholanthrene-induced sarcoma in mice: a preliminary report. ( Kahan, BD; Pellis, NR; Tanaka, T, 1982) |
| " We investigated murine soft tissue sarcomas generated by oncogenic alterations (KrasG12D activation and p53 deletion), carcinogens (3-methylcholanthrene [MCA] or ionizing radiation), and in a novel model combining both factors (MCA plus p53 deletion)." | 3.91 | Mutational landscape in genetically engineered, carcinogen-induced, and radiation-induced mouse sarcoma. ( Caraballo, I; Daniel, AR; Delaney, JR; Gresham, J; Kirsch, DG; Lee, CL; Luo, L; Mowery, YM; Owzar, K; Qin, X; Sibley, AB; Van Mater, D; Wang, X; Wisdom, AJ; Zhang, D, 2019) |
| " In this study, we observed that deficiency of either Fas or FasL resulted in significantly increased incidence of 3-methylcholanthrene-induced spontaneous sarcoma development in mice." | 3.78 | NF-κB directly regulates Fas transcription to modulate Fas-mediated apoptosis and tumor suppression. ( Bardhan, K; Ganapathy, V; Lee, JR; Liles, GB; Liu, F; Liu, K; Thangaraju, M; Waller, JL; Yang, D, 2012) |
| " Using 3-methylcholanthrene-induced primary mouse tumors, we examined the distinct regulation of Treg-mediated immunosuppression between carcinomas and sarcomas." | 3.76 | 3-Methylcholanthrene-induced transforming growth factor-beta-producing carcinomas, but not sarcomas, are refractory to regulatory T cell-depletion therapy. ( Chamoto, K; Kitamura, H; Matsushima, K; Nishimura, T; Ohkuri, T; Uchinami, Y; Wakita, D, 2010) |
| "Tumor-specific transplantation antigens (TSTA), which were partially purified by preparative isoelectric focusing of 3-M KCl extracts of a fibrosarcoma MCA-F induced in inbred female C3H/HeJ mice with 3-methylcholanthrene and previously shown to display immunotherapeutic activity against subcutaneous neoplasms, were effective against pulmonary metastases." | 3.66 | Immunotherapeutic effects of partially purified tumor-specific transplantation antigens on pulmonary metastases of a 3-methylcholanthrene-induced sarcoma in mice: a preliminary report. ( Kahan, BD; Pellis, NR; Tanaka, T, 1982) |
| "On day 16, anorexia has appeared only in CTR and STD-AOX animals." | 1.39 | Timing of antioxidant supplementation is critical in improving anorexia in an experimental model of cancer. ( Citro, G; De Luca, S; Fazi, L; Laviano, A; Mari, A; Molfino, A; Muscaritoli, M; Ramaccini, C; Rossi Fanelli, F, 2013) |
| "Carcinogen-induced mouse models of cancer have shown that primary tumour susceptibility is thereby enhanced in immune-compromised mice, whereas the capacity for such tumours to grow after transplantation into wild-type mice is reduced." | 1.38 | Expression of tumour-specific antigens underlies cancer immunoediting. ( Cheung, AF; DuPage, M; Jacks, T; Mazumdar, C; Schmidt, LM, 2012) |
| "A central tenet of cancer immunoediting is that T-cell recognition of tumour antigens drives the immunological destruction or sculpting of a developing cancer." | 1.38 | Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting. ( Allison, JP; Arthur, CD; Chen, YS; Demeter, R; Hundal, J; Koboldt, DC; Magrini, VJ; Mardis, ER; Matsushita, H; Old, LJ; Rickert, CG; Schreiber, RD; Shea, LK; Smyth, MJ; Uppaluri, R; Vesely, MD; Wendl, MC; White, JM; Wylie, T, 2012) |
| "Fibrosarcomas without metastasis were the only tumours observed in the MCA-treated quail, while quail treated with JM16 and MCA developed undifferentiated tumours, fibrosarcomas, lymphosarcomas or combinations with or without metastasis." | 1.36 | Role of Marek's disease herpesvirus in the induction of tumours in Japanese quail (Coturnix coturnix japonica) by methylcholanthrene. ( Blackmore, C; Mondal, SP; O'Connell, P; Schat, KA; Wakenell, PS, 2010) |
| "One-day-treated cells were polyploidized octaploid cells, but they returned to tetraploid cells." | 1.32 | Octaploid Meth-A cells are established from a highly polyploidized cell population. ( Fujikawa-Yamamoto, K; Miyagoshi, M; Yamagishi, H, 2003) |
| "Severe dysplasia or questionable squamous cell carcinoma in situ was noted at the site of the bronchial gland in a segment removed 8 weeks after transplantation, and invasive squamous cell carcinoma in a segment removed 15 weeks after transplantation." | 1.26 | Induction of squamous cell carcinoma in human bronchi transplanted into nude mice. ( Kameya, T; Kodama, T; Shimosato, Y; Tamai, S, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 127 (85.81) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 10 (6.76) | 29.6817 |
| 2010's | 10 (6.76) | 24.3611 |
| 2020's | 1 (0.68) | 2.80 |
| Authors | Studies |
|---|---|
| Polesso, F | 1 |
| Munks, MW | 1 |
| Rott, KH | 1 |
| Smart, S | 1 |
| Hill, AB | 1 |
| Moran, AE | 1 |
| Lee, CL | 1 |
| Mowery, YM | 1 |
| Daniel, AR | 1 |
| Zhang, D | 1 |
| Sibley, AB | 1 |
| Delaney, JR | 1 |
| Wisdom, AJ | 1 |
| Qin, X | 1 |
| Wang, X | 1 |
| Caraballo, I | 1 |
| Gresham, J | 1 |
| Luo, L | 1 |
| Van Mater, D | 1 |
| Owzar, K | 1 |
| Kirsch, DG | 1 |
| Ligtenberg, MA | 1 |
| Çınar, Ö | 1 |
| Holmdahl, R | 1 |
| Mougiakakos, D | 1 |
| Kiessling, R | 2 |
| Saddawi-Konefka, R | 1 |
| Seelige, R | 1 |
| Gross, ET | 1 |
| Levy, E | 1 |
| Searles, SC | 1 |
| Washington, A | 1 |
| Santosa, EK | 1 |
| Liu, B | 1 |
| O'Sullivan, TE | 1 |
| Harismendy, O | 1 |
| Bui, JD | 2 |
| Prehn, RT | 3 |
| McDONALD, JG | 1 |
| Chamoto, K | 1 |
| Wakita, D | 1 |
| Ohkuri, T | 1 |
| Uchinami, Y | 1 |
| Matsushima, K | 1 |
| Kitamura, H | 1 |
| Nishimura, T | 1 |
| Wakenell, PS | 1 |
| O'Connell, P | 1 |
| Blackmore, C | 1 |
| Mondal, SP | 1 |
| Schat, KA | 1 |
| STRONG, LC | 1 |
| Ghosh, A | 1 |
| Bera, S | 1 |
| Ray, S | 1 |
| Banerjee, T | 1 |
| Ray, M | 1 |
| DuPage, M | 1 |
| Mazumdar, C | 1 |
| Schmidt, LM | 1 |
| Cheung, AF | 1 |
| Jacks, T | 1 |
| Matsushita, H | 1 |
| Vesely, MD | 1 |
| Koboldt, DC | 1 |
| Rickert, CG | 1 |
| Uppaluri, R | 2 |
| Magrini, VJ | 1 |
| Arthur, CD | 1 |
| White, JM | 2 |
| Chen, YS | 1 |
| Shea, LK | 1 |
| Hundal, J | 1 |
| Wendl, MC | 1 |
| Demeter, R | 1 |
| Wylie, T | 1 |
| Allison, JP | 1 |
| Smyth, MJ | 3 |
| Old, LJ | 2 |
| Mardis, ER | 1 |
| Schreiber, RD | 3 |
| Liu, F | 1 |
| Bardhan, K | 1 |
| Yang, D | 1 |
| Thangaraju, M | 1 |
| Ganapathy, V | 1 |
| Waller, JL | 1 |
| Liles, GB | 1 |
| Lee, JR | 1 |
| Liu, K | 1 |
| Molfino, A | 1 |
| De Luca, S | 1 |
| Muscaritoli, M | 1 |
| Citro, G | 1 |
| Fazi, L | 1 |
| Mari, A | 1 |
| Ramaccini, C | 1 |
| Rossi Fanelli, F | 1 |
| Laviano, A | 1 |
| Fujikawa-Yamamoto, K | 2 |
| Yamagishi, H | 2 |
| Miyagoshi, M | 2 |
| ESER, S | 1 |
| ESER, G | 1 |
| SAXEN, EA | 1 |
| MAIN, JM | 1 |
| ABBOTT, CE | 1 |
| BAIN, GO | 1 |
| KOWALEWSKI, K | 1 |
| PETROV, NN | 1 |
| KLEIN, G | 1 |
| SJOGREN, HO | 1 |
| KLEIN, E | 1 |
| HELLSTROM, KE | 3 |
| MATSUYAMA, M | 3 |
| MAEKAWA, A | 1 |
| NAGAYO, T | 1 |
| BAYREUTHER, K | 1 |
| BOLONINA, NI | 1 |
| CRISPENS, CG | 1 |
| EASTLICK, HL | 1 |
| MOLLER, G | 2 |
| PASTERNAK, G | 3 |
| HORN, KH | 3 |
| GRAFFI, A | 4 |
| HOU, LT | 1 |
| WILLIS, RA | 1 |
| BETZLER, HJ | 1 |
| STEVENSON, JL | 2 |
| VON HAAM, E | 2 |
| ZALDIVAR, RS | 1 |
| ALIAGA, C | 1 |
| RODRIGUEZ, H | 1 |
| KAWAI, S | 1 |
| MELNIKOV, RA | 1 |
| KELLY, MG | 1 |
| NEWTON, WL | 1 |
| O'GARA, RW | 1 |
| TAKI, I | 1 |
| IIJIMA, H | 1 |
| MIYOSHI, I | 1 |
| GELMI, G | 1 |
| TENDELLA, E | 1 |
| SATO, K | 1 |
| BALLS, M | 1 |
| OJIMA, Y | 1 |
| SJOEGREN, HO | 2 |
| MAISIN, J | 1 |
| SJOEGEN, HO | 1 |
| YOSHIDA, TO | 2 |
| SOUTHAM, CM | 1 |
| BRONDZ, BD | 1 |
| USUBUCHI, I | 1 |
| DIMARCO, A | 1 |
| SOLDATI, M | 1 |
| FIORETTI, A | 1 |
| WOJEWSKI, A | 2 |
| LASKA, A | 2 |
| FALK, HL | 1 |
| KOTIN, P | 1 |
| THOMPSON, S | 1 |
| NAKAMURA, T | 1 |
| MCKHANN, CF | 2 |
| YAMADA, M | 1 |
| PERESE, DM | 1 |
| KIKUCHI, K | 1 |
| TSUJI, Y | 1 |
| ITAKURA, K | 1 |
| KATAGIRI, H | 1 |
| HORIE, K | 1 |
| GERICKE, D | 1 |
| MOELLER, E | 2 |
| ROESSLER, R | 1 |
| MIZUKAMI, T | 1 |
| TERESHCHENKO, IP | 1 |
| MATSUOKA, K | 1 |
| HOZUMI, M | 1 |
| KOYAMA, K | 1 |
| KAWACHI, T | 1 |
| NAGAO, M | 1 |
| SUGIMURA, T | 1 |
| RIGGOTT, JM | 1 |
| STEWART, HL | 1 |
| SNELL, KC | 1 |
| MORRIS, HP | 1 |
| ZAWIRSKA, B | 1 |
| TOTSUKA, S | 1 |
| MATSUMOTO, Y | 1 |
| KLEIN, J | 1 |
| MATSUMOTO, T | 1 |
| WEXLER, H | 1 |
| MINTON, JP | 1 |
| KETCHAM, AS | 2 |
| GARDNER, B | 1 |
| EISENBERG, E | 1 |
| SCHMIDT, DM | 1 |
| GORSKI, T | 1 |
| LAFFARGUE, P | 1 |
| SAMSO, A | 1 |
| FRANCOIS, H | 1 |
| LUTZ, BR | 1 |
| FULTON, GP | 1 |
| PATT, DI | 1 |
| HANDLER, AH | 1 |
| STEVENS, DF | 1 |
| OBERLING, C | 1 |
| GUERIN, M | 1 |
| Dunn, GP | 1 |
| Bruce, AT | 1 |
| Sheehan, KC | 1 |
| Shankaran, V | 1 |
| Diamond, MS | 1 |
| Koebel, CM | 2 |
| Arthur, C | 1 |
| Wood, PA | 1 |
| Bove, K | 1 |
| You, S | 1 |
| Chambers, A | 1 |
| Hrushesky, WJ | 1 |
| Vermi, W | 1 |
| Swann, JB | 1 |
| Zerafa, N | 1 |
| Rodig, SJ | 1 |
| Indrová, M | 1 |
| Bubeník, J | 1 |
| Lindsay, JM | 1 |
| Manning, L | 1 |
| Wood, GW | 1 |
| Höffken, K | 1 |
| Steih, U | 1 |
| Schmidt, CG | 1 |
| Tanaka, T | 1 |
| Pellis, NR | 1 |
| Kahan, BD | 1 |
| Lewis, JG | 1 |
| Pizzo, SV | 1 |
| Adams, DO | 1 |
| Shimosato, Y | 1 |
| Kodama, T | 1 |
| Tamai, S | 1 |
| Kameya, T | 1 |
| Brooks, AD | 1 |
| Ng, B | 1 |
| Liu, D | 1 |
| Brownlee, M | 1 |
| Burt, M | 1 |
| Federoff, HJ | 1 |
| Fong, Y | 1 |
| Anis, KV | 1 |
| Rajeshkumar, NV | 2 |
| Kuttan, R | 2 |
| Wang, S | 1 |
| Ciupitu, AM | 1 |
| Petersson, M | 1 |
| Kono, K | 1 |
| Charo, J | 1 |
| Higuchi, M | 1 |
| More, R | 1 |
| Yron, I | 1 |
| Sasson, SB | 1 |
| Weiss, DW | 1 |
| Sakamoto, M | 1 |
| Nishioka, K | 1 |
| Basombrío, MA | 3 |
| Pasqualini, CD | 1 |
| Pearlstein, E | 1 |
| Hynes, RO | 1 |
| Franks, LM | 1 |
| Hemmings, VJ | 1 |
| Lezhneva, OM | 1 |
| Le Mevel, BP | 1 |
| Wells, SA | 1 |
| Lafreniere, R | 1 |
| Rosenberg, SA | 1 |
| Roh, MS | 1 |
| Ekman, LG | 1 |
| Jeevanandam, M | 1 |
| Brennan, MF | 1 |
| Farbiszewski, R | 1 |
| Sokół, A | 1 |
| London, RS | 1 |
| Murphy, L | 1 |
| Kitlowski, KE | 1 |
| Homburger, F | 2 |
| Berczi, I | 1 |
| Strausbauch, P | 1 |
| Sehon, AH | 1 |
| Wahl, DV | 1 |
| Chapman, WH | 1 |
| Hellström, I | 1 |
| Baum, H | 1 |
| Baum, M | 1 |
| Arnold, W | 1 |
| Nouza, K | 1 |
| Nĕmec, M | 1 |
| Dráber, P | 1 |
| Angel Basombrío, M | 1 |
| Ronzoni, G | 1 |
| Alquati, P | 1 |
| Pola, P | 1 |
| Alcini, E | 1 |
| Gardner, MB | 1 |
| Officer, JE | 1 |
| Rongey, RW | 1 |
| Estes, JD | 1 |
| Turner, HC | 1 |
| Huebner, RJ | 3 |
| Whitmire, CE | 2 |
| Baldwin, RW | 2 |
| Glaves, D | 1 |
| Vose, BM | 1 |
| Stoner, GD | 1 |
| Kniazeff, AJ | 1 |
| Shimkin, MB | 1 |
| Hoppenstand, RD | 1 |
| Seeger, RC | 1 |
| Rayner, SA | 1 |
| Owen, JJ | 1 |
| Kato, T | 1 |
| Yakushiji, M | 1 |
| Tsunawaki, A | 1 |
| Ide, K | 1 |
| Cohen, AM | 1 |
| Shvemberger, IN | 1 |
| Ivashkevich, LG | 1 |
| Vakhtin, IuB | 1 |
| Pimm, MV | 1 |
| Kouri, RE | 1 |
| Salerno, RA | 1 |
| Post, J | 1 |
| Sklarew, RJ | 1 |
| Hoffman, J | 1 |
| Smith, MS | 1 |
| Hartman, S | 1 |
| Kern, DH | 1 |
| Pilch, YH | 2 |
| Kroh, H | 1 |
| Szumańska, G | 1 |
| Hsueh, SS | 1 |
| Kerr, CS | 1 |
| Russfield, AB | 2 |
| Hirao, F | 1 |
| Tokuoka, S | 1 |
| Sil, R | 1 |
| Neel, HB | 1 |
| Hammond, WG | 2 |
| Iversen, U | 1 |
| Iversen, OH | 1 |
| Hennings, H | 1 |
| Bjerknes, R | 1 |
| Harder, FH | 1 |
| Morgenstern, L | 1 |
| Castillo, JL | 1 |
| Goldsmith, HS | 1 |
| Neiman, JM | 1 |
| Blanzat-Reboud, S | 1 |
| Bard, DS | 1 |
| Karahashi, Y | 1 |
| Sheptak, P | 1 |
| Moossy, J | 1 |
| Goldring, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Identifying Genetic Predictors of Durable Clinical Benefit to Pembrolizumab in Advanced Non-small Cell Lung Cancer (NSCLC) Alone and in Combination With Chemotherapy.[NCT02710396] | Phase 2 | 19 participants (Actual) | Interventional | 2016-05-31 | Terminated (stopped due to Frontline pembrolizumab approved in NSCLC as monotherapy and in combination with chemotherapy representing a new standard of care.) | ||
| A Randomized Phase II Study Evaluating Pembrolizumab vs Topotecan in the Second-Line Treatment of Patients With Small Cell Lung Cancer[NCT02963090] | Phase 2 | 9 participants (Actual) | Interventional | 2017-05-20 | Terminated (stopped due to Lack of enrollment) | ||
| Determining Levels of [D10] Phenanthrene Tetraol in Smokers' Urine[NCT01092650] | Phase 1 | 30 participants (Anticipated) | Interventional | 2007-09-30 | Completed | ||
| Effects of Epidural Anesthesia-analgesia on Long-term Survival in Patients After Lung Cancer Surgery: A Randomized Controlled Trial[NCT02801409] | 400 participants (Actual) | Interventional | 2015-05-25 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Objective response to study treatment will be assessed by RECIST 1.1 by a study radiologist. Partial and complete responses will be confirmed by a repeat imaging occurring at least 4 weeks after the initial identification of response; unconfirmed responses will be considered stable or progressive disease dependent on results of the second CT scan. Durable clinical benefit (DCB) will be defined as stable disease (Neither sufficient shrinkage to qualify for partial response nor sufficient increase to qualify for progressive disease, taking as reference the smallest sum diameters while on study), OR complete response (disappearance of all target lesions. Any pathological lymph nodes (whether target or non-target) must have reduction in short axis to <10 mm.), OR partial response (At least a 30% decrease in the sum of diameters of target lesions, taking as reference the baseline sum diameters) lasting longer than 6 months. (NCT02710396)
Timeframe: Up to 2 years
| Intervention | Participants (Count of Participants) |
|---|---|
| Cohort 1 | 3 |
| Cohort 2 | 0 |
| Cohort 3 | 0 |
ORR is defined as participants with a partial (At least a 30% decrease in the sum of diameters of target lesions, taking as reference the baseline sum diameters) or complete response (Disappearance of all target lesions. Any pathological lymph nodes (whether target or non-target) must have reduction in short axis to <10 mm) as assessed by RECIST 1.1 criteria. (NCT02710396)
Timeframe: Up to 2 years
| Intervention | Participants (Count of Participants) |
|---|---|
| Cohort 1 | 4 |
| Cohort 2 | 1 |
| Cohort 3 | 0 |
The length of time from the start of treatment to death. (NCT02710396)
Timeframe: Up to 28 months
| Intervention | Months (Median) |
|---|---|
| Cohort 1 | 14.06 |
| Cohort 2 | 23.49 |
The length of time from treatment initiation to progression of disease (at least a 20% increase in the sum of diameters of target lesions, taking as reference the smallest sum on study (this includes the baseline sum if that is the smallest on study). In addition to the relative increase of 20%, the sum must also demonstrate an absolute increase of at least 5 mm. The appearance of one or more new lesions is also considered progression) as assessed by RECIST 1.1. (NCT02710396)
Timeframe: Up to 2 years
| Intervention | months (Median) |
|---|---|
| Cohort 1 | 4.80 |
| Cohort 2 | 3.94 |
"RECIST Version 1.1* will be used in this study for assessment for tumor response.~Complete Response (CR): All of the following must be true:~Disappearance of all target lesions.~Each target lymph node must have reduction in short axis to < 1.0 cm. • Partial Response (PR): At least a 30% decrease in PBSD (sum of the longest diameter for all target lesions plus the sum of the short axis of all the target lymph nodes at current evaluation) taking as reference the BSD" (NCT02963090)
Timeframe: 4.2 months
| Intervention | percentage of participants (Number) |
|---|---|
| Topotecan (Arm A) | 0 |
| Pembrolizumab (Arm B) | 0 |
Overall survival will be calculated from the time a patient is registered until the time of death or discontinuation of followup (NCT02963090)
Timeframe: 20 months
| Intervention | Months (Median) |
|---|---|
| Topotecan (Arm A) | NA |
| Pembrolizumab (Arm B) | 10.7 |
This phase II study will determine if there is a benefit in progression free survival (PFS) for SCLC patients receiving pembrolizumab (Experimental arm) as compared to topotecan (Control arm) in the second-line settingSCLC patients receiving pembrolizumab (Experimental arm) as compared to topotecan (Control arm) in the second-line setting. RECIST Version 1.1 was used in this study for assessment for tumor response. Progression (PD): At least one of the following must be true: a. At least one new malignant lesion, which also includes any lymph node that was normal at baseline (< 1.0 cm short axis) and increased to ≥ 1.0 cm short axis during follow-up. b. At least a 20% increase in PBSD (sum of the longest diameter for all target lesions plus the sum of the short axis of all the target lymph nodes at current evaluation) taking as reference the MSD. In addition, the PBSD must also demonstrate an absolute increase of at least 0.5 cm from the MSD. (NCT02963090)
Timeframe: 4.2 months
| Intervention | Months (Median) |
|---|---|
| Topotecan (Arm A + Crossover Patients) | 1.4 |
| Pembrolizumab | 1.5 |
4 reviews available for 3-methylcholanthrene and Sarcoma, Epithelioid
| Article | Year |
|---|---|
Mitomycin C.
Topics: Animals; Carcinogens; Chromosome Aberrations; Crosses, Genetic; Drug Evaluation, Preclinical; Female | 1976 |
Transplantation immunity to individually unique antigens of chemically induced bladder tumors in mice.
Topics: Animals; Antibody Formation; Antigen-Antibody Reactions; Antigens, Neoplasm; Carcinoma; Cell Line; E | 1974 |
The immunology of cancer.
Topics: Animals; Antibodies, Neoplasm; Antigen-Antibody Complex; Antigens, Neoplasm; Breast Neoplasms; Colon | 1973 |
Identification of leukemogenic viruses: specifications for vertically transmitted, mostly 'switched off' RNA tumor viruses as determinants of the generality of cancer.
Topics: Aging; Animals; Antigens, Viral; Cats; Chickens; Embryo, Mammalian; Embryo, Nonmammalian; Genes; Gen | 1970 |
144 other studies available for 3-methylcholanthrene and Sarcoma, Epithelioid
| Article | Year |
|---|---|
PD-1-specific "Blocking" antibodies that deplete PD-1
Topics: Animals; B7-H1 Antigen; CD8-Positive T-Lymphocytes; Cell Death; Cell Line, Tumor; Cricetinae; Diseas | 2021 |
Mutational landscape in genetically engineered, carcinogen-induced, and radiation-induced mouse sarcoma.
Topics: Animals; Carcinogenesis; Carcinogens; DNA Mutational Analysis; Exome Sequencing; Genomic Instability | 2019 |
Methylcholanthrene-Induced Sarcomas Develop Independently from NOX2-Derived ROS.
Topics: Animals; CD4-CD8 Ratio; Cell Transformation, Neoplastic; Disease Models, Animal; Immunologic Memory; | 2015 |
Nrf2 Induces IL-17D to Mediate Tumor and Virus Surveillance.
Topics: Animals; Carcinogens; Cell Line, Tumor; Chlorocebus aethiops; Gene Expression Regulation; Humans; Im | 2016 |
Analysis of antigenic heterogeneity within individual 3-methylcholanthrene-induced mouse sarcomas.
Topics: Animals; Antigens, Neoplasm; Carcinogens; Epitopes; Methylcholanthrene; Mice; Sarcoma | 1970 |
Production of reticulum cell sarcoma and fibrosarcoma by methylcholanthrene adsorbed on activated carbon.
Topics: Animals; Carbon; Fibrosarcoma; Lymphoma, Non-Hodgkin; Methylcholanthrene; Neoplasms; Sarcoma | 1947 |
3-Methylcholanthrene-induced transforming growth factor-beta-producing carcinomas, but not sarcomas, are refractory to regulatory T cell-depletion therapy.
Topics: Animals; Antibodies, Monoclonal; Carcinoma, Squamous Cell; Female; Interleukin-2 Receptor alpha Subu | 2010 |
Role of Marek's disease herpesvirus in the induction of tumours in Japanese quail (Coturnix coturnix japonica) by methylcholanthrene.
Topics: Animals; Coturnix; DNA Primers; DNA, Neoplasm; Fibrosarcoma; Lymphoma, Non-Hodgkin; Mardivirus; Mare | 2010 |
Genetic analysis of the induction of tumors by methylcholanthrene; mutation from brown to black with a concomitant increase of susceptibility to fibrosarcoma.
Topics: Disease; Fibrosarcoma; Genetic Testing; Heredity; Humans; Methylcholanthrene; Mutation; Neoplasms; S | 1946 |
Methylglyoxal induces mitochondria-dependent apoptosis in sarcoma.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cytochromes c; Female; Membrane Potential, Mitochondrial; Meth | 2011 |
Expression of tumour-specific antigens underlies cancer immunoediting.
Topics: Animals; Antigens, Neoplasm; Disease Models, Animal; Gene Expression Regulation, Neoplastic; HEK293 | 2012 |
Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting.
Topics: Algorithms; Animals; Carrier Proteins; DNA-Binding Proteins; Exome; Histocompatibility Antigens Clas | 2012 |
Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting.
Topics: Algorithms; Animals; Carrier Proteins; DNA-Binding Proteins; Exome; Histocompatibility Antigens Clas | 2012 |
Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting.
Topics: Algorithms; Animals; Carrier Proteins; DNA-Binding Proteins; Exome; Histocompatibility Antigens Clas | 2012 |
Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting.
Topics: Algorithms; Animals; Carrier Proteins; DNA-Binding Proteins; Exome; Histocompatibility Antigens Clas | 2012 |
NF-κB directly regulates Fas transcription to modulate Fas-mediated apoptosis and tumor suppression.
Topics: Animals; Apoptosis; Caspase 8; Colonic Neoplasms; Embryo, Mammalian; Fas Ligand Protein; fas Recepto | 2012 |
Timing of antioxidant supplementation is critical in improving anorexia in an experimental model of cancer.
Topics: Animals; Anorexia; Antioxidants; Ascorbic Acid; Body Weight; Diet; Dietary Supplements; Disease Mode | 2013 |
Octaploid Meth-A cells are established from a highly polyploidized cell population.
Topics: Animals; Cell Cycle; Cell Division; Demecolcine; DNA, Neoplasm; Karyotyping; Methylcholanthrene; Mic | 2003 |
[The therapeutic action of acetylcholine on sarcomas induced by methylcholanthrene].
Topics: Acetylcholine; Animals; Methylcholanthrene; Sarcoma; Sarcoma, Experimental | 1954 |
On the factor of age in the production of subcutaneous sarcomas in mice by 20-methylcholanthrene.
Topics: Aging; Animals; Methylcholanthrene; Mice; Neoplasms, Experimental; Sarcoma; Sarcoma, Experimental | 1953 |
Immunity to methylcholanthrene-induced sarcomas.
Topics: Methylcholanthrene; Neoplasms; Sarcoma | 1957 |
Effect of radiothyroidectomy on methylcholanthrene-induced sarcoma in the rat.
Topics: Animals; Iodine; Iodine Radioisotopes; Methylcholanthrene; Neoplasms; Radioisotopes; Rats; Sarcoma; | 1958 |
[Further observations on the monkey Tomilla after hip amputation in sarcoma caused by methylcholanthrene].
Topics: Amputation, Surgical; Animals; Femur; Haplorhini; Methylcholanthrene; Neoplasms; Sarcoma; Sarcoma, E | 1960 |
Demonstration of resistance against methylcholanthrene-induced sarcomas in the primary autochthonous host.
Topics: Animals; Methylcholanthrene; Sarcoma; Sarcoma, Experimental | 1960 |
Inhibiting effect of nicotinamide and diphosphopyridine nucleotide on the methylcholanthrene sarcoma in rats.
Topics: Animals; Coenzymes; Methylcholanthrene; NAD; Neoplasms; Niacin; Niacinamide; Nicotinic Acids; Rats; | 1961 |
The chromosomal constitution of methyl-cholanthrene induced sarcomas and their variants induced and tested in isogenic resistant strains.
Topics: Animals; Benz(a)Anthracenes; Chromosomes; Methylcholanthrene; Sarcoma; Sarcoma, Experimental | 1960 |
[Tumors induce in Lagurus lagurus Pall. by methylcholanthrene. A transplantable strain of sarcoma in Lagurus].
Topics: Animals; Methylcholanthrene; Neoplasms; Sarcoma; Sarcoma, Experimental; Transplants | 1960 |
Chorioallantoic grafts of a methylcholanthrene-induced chicken sarcoma.
Topics: Animals; Chickens; Extraembryonic Membranes; Membranes; Methylcholanthrene; Sarcoma; Sarcoma, Experi | 1960 |
Studies on the effect of humoral isoantibodies on tumor growth.
Topics: Animals; Complementary Therapies; Immune Sera; Isoantibodies; Methylcholanthrene; Neoplasms; Sarcoma | 1963 |
[The induction of isoimmunity to methylcholanthrene tumors in mice].
Topics: Animals; Antigen-Antibody Reactions; Methylcholanthrene; Mice; Neoplasms; Sarcoma; Sarcoma, Experime | 1962 |
[Experiments on induction of immunity to methylcholanthrene tumors by pre-treatment of mice with homologous and heterologous tumor transplants].
Topics: Animals; Antigen-Antibody Reactions; Carcinoma; Carcinoma, Ehrlich Tumor; Immunity; Methylcholanthre | 1962 |
Effect of cigarette-smoke condensates on homografts of embryonic lung tissue in rats.
Topics: Allografts; Animals; Carcinogens; Carcinoma; Carcinoma, Squamous Cell; Lung; Methylcholanthrene; Nic | 1963 |
[Observations on subcutaneously and intramuscularly induced methylcholanthrene tumors in rats].
Topics: Animals; Injections, Intramuscular; Methylcholanthrene; Neoplasms; Rats; Sarcoma; Sarcoma, Experimen | 1963 |
The induction of sarcomas in the colon of rats by intraluminal application of hydrocarbons.
Topics: Adenocarcinoma; Animals; Benzopyrenes; Carcinoma, Squamous Cell; Colonic Diseases; Lymphoma; Lymphom | 1963 |
Induction of kidney tumors in mice by the use of 20-methylcholanthrene-impregnated strings.
Topics: Animals; Carcinoma; Kidney Neoplasms; Methylcholanthrene; Mice; Neoplasms; Sarcoma; Sarcoma, Experim | 1962 |
Epithelial lesions of the stomach induced in guinea pigs by intramural implantation of 3-methylcholanthrene.
Topics: Animals; Diverticulum, Stomach; Guinea Pigs; Leiomyosarcoma; Methylcholanthrene; Neoplasms; Sarcoma; | 1962 |
[EXPERIMENTAL STUDIES ON BRAIN TUMORS].
Topics: Animals; Brain Neoplasms; Glioma; Methylcholanthrene; Mice; Neoplasms; Neoplasms, Experimental; Path | 1963 |
THE INDUCTION OF TUMORS IN MONKEYS AND RABBITS BY CHEMICAL AND RADIATION AGENTS.
Topics: Animals; Benz(a)Anthracenes; Carcinoma, Squamous Cell; Cobalt Isotopes; Haplorhini; Maxillary Neopla | 1963 |
SUSCEPTIBILITY OF NEWBORN GERM-FREE MICE TO TUMOR INDUCTION BY 3-METHYLCHOLANTHRENE.
Topics: Animals; Germ-Free Life; Leukemia; Leukemia, Experimental; Lung Neoplasms; Methylcholanthrene; Mice; | 1963 |
[STUDIES ON THE PERSISTENCE OF TUMOR-SPECIFIC ANTIGENS IN METHYLCHOLANTHRENE-INDUCED SARCOMA IN MICE AFTER VARIOUS TRANSPLANTATION PASSAGES IN ISOLOGOUS HOSTS AND F1 HYBRIDS].
Topics: Animals; Methylcholanthrene; Mice; Neoplasms; Radiation Effects; Research; Sarcoma; Sarcoma, Experim | 1963 |
FUNCTION OF DEPRESSED IMMUNOLOGIC REACTIVITY DURING CARCINOGENESIS.
Topics: Carcinogenesis; Fibrosarcoma; Methylcholanthrene; Mice; Neoplasms; Neoplasms, Experimental; Research | 1963 |
A NEW METHOD OF PRODUCING ENDOMETRIAL CANCER IN MICE.
Topics: Adenocarcinoma; Animals; Carcinoma, Squamous Cell; Endometrial Neoplasms; Endometrium; Female; Human | 1963 |
ACCELERATION OF THE DEVELOPMENT OF LEUKEMIA AND INDUCTION OF TUMORS IN AKR MICE BY NEONATAL INJECTION OF 20-METHYLCHOLANTHRENE.
Topics: Adenoma; Animals; Carcinogens; Leukemia; Leukemia, Experimental; Leukemia, Lymphoid; Lung Neoplasms; | 1963 |
[EXPERIMENTS WITH SERO-PROPHYLAXIS AND SERO-THERAPY OF AN EXPERIMENTAL TUMOR].
Topics: Abdominal Neoplasms; Animals; Carcinogens; Immune Sera; Immunization, Passive; Methylcholanthrene; N | 1963 |
[EXPERIMENTAL STUDIES ON BRAIN TUMORS, WITH SPECIAL REFERENCE TO GLIOMAS AND THEIR TRANSPLANTS IN THE MOUSE].
Topics: Animals; Brain Neoplasms; Cerebellar Neoplasms; Electrons; Glioma; Methylcholanthrene; Mice; Microsc | 1963 |
TRANSPLANTATION OF SPONTANEOUSLY OCCURRING AND CHEMICALLY INDUCED LYMPHOID TUMORS IN XENOPUS LAEVIS.
Topics: Amphibians; Animals; Carcinogens; Lymphoma; Lymphoma, Non-Hodgkin; Methylcholanthrene; Neoplasms; Pa | 1964 |
EXPERIMENTAL STUDIES ON THE INFLUENCE OF RETICULO-ENDOTHELIAL SYSTEM UPON THE INDUCTION OF MALIGNANT GASTRIC NEOPLASMS.
Topics: Adenocarcinoma; Alcohols; Ethanol; Methylcholanthrene; Mononuclear Phagocyte System; Neoplasms; Neop | 1963 |
STUDIES ON SPECIFIC TRANSPLANTATION RESISTANCE TO POLYOMA-VIRUS-INDUCED TUMORS. I. TRANSPLANTATION RESISTANCE INDUCED BY POLYOMA VIRUS INFECTION.
Topics: Animals; Lymphoma; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Methylcholanthrene; M | 1964 |
STUDIES ON SPECIFIC TRANSPLANTATION RESISTANCE TO POLYOMA-VIRUS-INDUCED TUMORS. IV. STABILITY OF THE POLYOMA CELL ANTIGEN.
Topics: Antigens; Genetics; Methylcholanthrene; Mice; Neoplasms; Oncogenic Viruses; Polyomavirus; Research; | 1964 |
[ATTEMPTED IMMUNOPROPHYLAXIS OF EXPERIMENTALLY INDUCED CANCERS].
Topics: Animals; Carcinoma, Hepatocellular; Immunization; Liver Neoplasms; Methylcholanthrene; Mice; Neoplas | 1964 |
STUDIES ON SPECIFIC TRANSPLANTATION RESISTANCE TO POLYOMA-VIRUS-INDUCED TUMORS. III. TRANSPLANTATION RESISTANCE TO GENETICALLY COMPATIBLE POLYOMA TUMORS INDUCED BY POLYOMA TUMOR HOMOGRAFTS.
Topics: Allografts; Benzopyrenes; Carcinogens; Cellophane; Genetics; Methylcholanthrene; Mice; Neoplasms; Ne | 1964 |
ATTEMPTS TO FIND CELL ASSOCIATED IMMUNE REACTION AGAINST AUTOCHTHONOUS TUMORS.
Topics: Benz(a)Anthracenes; Carcinogens; Hemagglutination; Methylcholanthrene; Mice; Neoplasms; Neoplasms, E | 1963 |
[ANTIBODIES AGAINST THE SPECIFIC ANTIGEN OF THE TUMOR CELL MEMBRANE].
Topics: Animals; Benz(a)Anthracenes; Cell Membrane; Immune Sera; Immunization; Methylcholanthrene; Mice; Neo | 1964 |
ADMINISTRATION METHOD OF MITOMYCIN C.
Topics: Carcinoma, Hepatocellular; Liver Neoplasms; Methylcholanthrene; Mitomycin; Mitomycins; Neoplasms; Ne | 1964 |
THE ANTIMITOTIC ACTIVITY OF ANTIBIOTIC DISTAMYCIN A.
Topics: Anti-Bacterial Agents; Antimitotic Agents; Antineoplastic Agents; Cell Division; Chick Embryo; Chrom | 1964 |
EXPERIMENTAL CANCER OF THE PROSTATE.
Topics: Carcinoma, Squamous Cell; Castration; Estradiol; Humans; Male; Methylcholanthrene; Neoplasms; Prosta | 1964 |
INHIBITION OF CARCINOGENESIS. THE EFFECT OF HYDROCARBONS AND RELATED COMPOUNDS.
Topics: Animals; Antineoplastic Agents; Benz(a)Anthracenes; Benzopyrenes; Carcinogenesis; Carcinogens; Glyco | 1964 |
HOMOLOGOUS TUMOUR GROWTH IN METHYLCHOLANTHRENE-INDUCED SARCOMA-BEARING MICE.
Topics: Animals; Carcinogens; Fibrosarcoma; Methylcholanthrene; Mice; Neoplasms; Neoplasms, Experimental; Ph | 1964 |
THE EFFECT OF X-RAY ON THE ANTIGENICITY OF DONOR CELLS IN TRANSPLANTATION IMMUNITY.
Topics: Allergy and Immunology; Antigens; Immunization; Methylcholanthrene; Mice; Myosarcoma; Radiation Effe | 1964 |
[EXPERIMENTAL STUDIES OF BONE TUMORS INDUCED BY 20-METHYLCHOLANTHRENE IN MICE. 1. INFLUENCE OF TRAUMA (FRACTURE) ON THE DEVELOPMENT OF MALIGNANT BONE TUMORS].
Topics: Animals; Bone Neoplasms; Femoral Fractures; Femoral Neoplasms; Methylcholanthrene; Mice; Neoplasms; | 1964 |
AUTOLOGOUS AND HOMOLOGOUS TUMOR TRANSPLANTATION IN ANIMALS BEARING METHYLCHOLANTHRENE-INDUCED SARCOMA.
Topics: Animals; Methylcholanthrene; Neoplasm Transplantation; Neoplasms; Rats; Research; Sarcoma; Sarcoma, | 1964 |
AGE AND SEX FACTORS IN EXPERIMENTAL BRAIN TUMORS.
Topics: Aging; Animals; Brain Abscess; Brain Neoplasms; Carcinoma, Squamous Cell; Glioblastoma; Glioma; Meth | 1964 |
A CASE OF METASTASES OF GASTRIC CANCER TO HYPERNEPHROMA AND ITS METASTATIC FOCI.
Topics: Adenocarcinoma; Carcinoma, Hepatocellular; Carcinoma, Renal Cell; Kidney Neoplasms; Liver Neoplasms; | 1964 |
PATHOLOGICAL STUDIES ON EXPERIMENTAL BONE TUMOR.
Topics: Alkaline Phosphatase; Animals; Benzopyrenes; Bone Neoplasms; Carcinogens; Croton Oil; Histocytochemi | 1964 |
[EXPERIENCE WITH ETHYLENEIMINES].
Topics: Animals; Antineoplastic Agents; Aziridines; Carcinoma 256, Walker; Carcinoma, Ehrlich Tumor; Leukemi | 1964 |
EFFECT ON TUMOUR GROWTH IN SYNGENEIC RECIPIENTS OF ANTIBODIES AGAINST TUMOUR-SPECIFIC ANTIGENS IN METHYLCHOLANTHRENE-INDUCED MOUSE SARCOMAS.
Topics: Animals; Antibodies; Fluorescent Antibody Technique; Immune Sera; Immunization; Methylcholanthrene; | 1964 |
ISOANTIGENIC PROPERTIES OF TUMORS TRANSGRESSING HISTOCOMPATIBILITY BARRIERS OF THE H-2 SYSTEM.
Topics: Animals; Antigen-Antibody Reactions; Antigens; Genetics; Hemagglutination; Isoantigens; Methylcholan | 1964 |
[APROPOS OF THE PRODUCTION OF TUMORS OF THE URINARY BLADDER IN EXPERIMENTAL ANIMALS].
Topics: Animals; Methylcholanthrene; Neoplasm Transplantation; Neoplasms; Neoplasms, Experimental; Rabbits; | 1964 |
CANCER AND MESENCHYMAL SYSTEM.
Topics: Animals; Benzopyrenes; Carcinogens; Carcinoma; Carcinoma, Ehrlich Tumor; Connective Tissue; Cortison | 1964 |
PECULIARITIES OF CANCEROGENESIS IN ANIMALS WITH DIFFERENT INITIAL RESISTANCE TO TUMOR GROWTH.
Topics: Adaptation, Physiological; Animals; Denervation; Genetics; Methylcholanthrene; Mice; Neoplasms; Neop | 1964 |
CONTACT-INDUCED CYTOTOXICITY BY LYMPHOID CELLS CONTAINING FOREIGN ISOANTIGENS.
Topics: Animals; Antigens; Culture Media; H-2 Antigens; Immune Sera; Immunization; Immunologic Tests; Isoant | 1965 |
[TUMOR TOXOHORMONE UNRELATED TO BACTERIAL CONTAMINATION].
Topics: Catalase; Endotoxins; Fibrosarcoma; Hormones; Liver; Methylcholanthrene; Mice; Neoplasms; Rats; Rese | 1964 |
THE CHEMICAL INDUCTION OF BREAST TUMOURS IN C57BL, IF AND F1, HYBRID (C57BL X IF) BREAST TISSUE TRANSPLANTED INTO BREAST-FREE F1 HYBRID (C57BL X IF) HOSTS.
Topics: Adenocarcinoma; Animals; Breast Neoplasms; Carcinogens; Genetics; Humans; Mammary Glands, Animal; Ma | 1965 |
(THE COMBINED EFFECT OF 3-METHYLCHOLANTHRENE AND N,N'-2,7-FLUORENYLENEBISACETMIDE ON THE INDUCTION OF CANCER OF THE GLANDULAR STOMACH OF THE RAT.)
Topics: Abdominal Neoplasms; Abdominal Wall; Atrophy; Carcinogens; Ethmoid Bone; Female; Humans; Inflammatio | 1965 |
MICROFLUOROSCOPIC STUDIES ON PORPHYRINS IN HARDER'S GLAND AND IN TUMORS INDUCED IN IT. II. MICROFLUOROSCOPIC STUDIES ON PORPHYRINS IN PRECANCEROUS STATES AND TUMORS INDUCED WITH METHYLCHOLANTHRENE IN HARDER'S GLAND IN WHITE RATS.
Topics: Adenoma; Animals; Carcinogens; Eye Neoplasms; Fluorescence; Histocytochemistry; Lacrimal Apparatus; | 1965 |
[HISTOLOGICAL AND HISTOCHEMICAL STUDIES ON THE HISTOGENESIS OF EXPERIMENTALLY INDUCED MENINGEAL SARCOMA)].
Topics: Animals; Histocytochemistry; Meningeal Neoplasms; Meningioma; Methylcholanthrene; Mice; Neoplasms; P | 1965 |
FURTHER EVIDENCE OF IMMUNOLOGIC REACTION AGAINST METHYLCHOLANTHRENE-INDUCED AUTOCHTHONOUS TUMORS.
Topics: Animals; Antigen-Antibody Reactions; Complement Fixation Tests; Methylcholanthrene; Mice; Neoplasms; | 1965 |
CHANGES OF TRANSPLANTATION CHARACTERISTICS IN METHYLCHOLANTHRENE-INDUCED TUMOURS. ISOLATION OF SPECIFIC ISOANTIGENIC VARIANTS.
Topics: Animals; Antigens; Genetics; Isoantigens; Methylcholanthrene; Mice; Neoplasm Transplantation; Neopla | 1965 |
ANTIGENICITY OF A CRUDE LIPOPOLYSACCHARIDE FRACTION OF THE METHYLCHOLANTHRENE-INDUCED TUMOR, WITH SPECIAL REFERENCE TO ISOLOGOUS IMMUNITY IN INBRED RATS.
Topics: Adsorption; Antigens; Hemagglutination; Immune Sera; Lipopolysaccharides; Methylcholanthrene; Neopla | 1965 |
A COMPARISON OF SURVIVAL TIME AND EXTENT OF TUMOR METASTASES IN MICE WITH TRANSPLANTED, INDUCED AND SPONTANEOUS TUMORS.
Topics: Animals; Carcinogens; Ethiodized Oil; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Me | 1965 |
FAILURE OF OSTEOLYTIC AGENTS TO INDUCE SKELETAL METASTASES IN RATS WITH SARCOMA.
Topics: Animals; Bone Neoplasms; Carcinogens; Cholecalciferol; Injections, Subcutaneous; Methylcholanthrene; | 1965 |
[BEHAVIOR OF THE ISLANDS OF LANGERHANS DURING THE ACTION OF CARCINOGENIC SUBSTANCES IN THE PANCREAS OF MICE].
Topics: Animals; Carcinogens; Islets of Langerhans; Methylcholanthrene; Mice; Neoplasms; Pancreas; Research; | 1965 |
Chromosomal studies on primary methyl-cholanthrene-induced sarcomas in the mouse.
Topics: Animals; Benz(a)Anthracenes; Chromosomes; Methylcholanthrene; Mice; Sarcoma; Sarcoma, Experimental | 1959 |
[Sarcoma of the cervix uteri in mice produced with methylcholanthrene].
Topics: Animals; Female; Humans; Methylcholanthrene; Mice; Neoplasms; Neoplasms, Experimental; Sarcoma; Sarc | 1961 |
The cheek pouch of the hamster as a site for the transplantation of a methyl-cholanthrene-induced sarcoma.
Topics: Animals; Benz(a)Anthracenes; Cheek; Cricetinae; Humans; Methylcholanthrene; Neoplasms; Sarcoma | 1951 |
[Filtrable fowl sarcoma caused by methylcholanthrene].
Topics: Filtration; Methylcholanthrene; Neoplasms; Sarcoma; Software | 1950 |
A critical function for type I interferons in cancer immunoediting.
Topics: Animals; DNA-Binding Proteins; Hematopoiesis; Interferon-alpha; Membrane Proteins; Methylcholanthren | 2005 |
Cancer growth and spread are saltatory and phase-locked to the reproductive cycle through mediators of angiogenesis.
Topics: Animals; Blood Vessels; Capillary Permeability; Estrous Cycle; Female; Fibroblast Growth Factor 2; G | 2005 |
Adaptive immunity maintains occult cancer in an equilibrium state.
Topics: Animals; Antibodies, Monoclonal; Cell Proliferation; Disease Progression; DNA-Binding Proteins; Fema | 2007 |
Clarification of data used in three studies on MCA-induction of sarcoma in mice.
Topics: Animals; Methylcholanthrene; Mice; Reproducibility of Results; Sarcoma | 2008 |
Non T suppressor cells in the lymph nodes of mice bearing methylcholanthrene-induced sarcomas.
Topics: Animals; Cytotoxicity, Immunologic; Immune Sera; Lymph Nodes; Male; Methylcholanthrene; Mice; Sarcom | 1981 |
Exclusive binding of immunoglobulin to Fc gamma receptors on macrophages in 3-methylcholanthrene-induced murine tumors.
Topics: Animals; Antigen-Antibody Complex; Fluorescent Antibody Technique; Glucans; Macrophages; Male; Methy | 1982 |
Immunogenicity of cellular and acellular antigen preparations from a methylcholanthrene-induced mouse sarcoma.
Topics: Animals; Antibody Formation; Antigens, Neoplasm; BCG Vaccine; Cross-Linking Reagents; Fluorescent An | 1982 |
Immunotherapeutic effects of partially purified tumor-specific transplantation antigens on pulmonary metastases of a 3-methylcholanthrene-induced sarcoma in mice: a preliminary report.
Topics: Animals; Antigens, Neoplasm; Female; Lung Neoplasms; Methylcholanthrene; Mice; Mice, Inbred C3H; Neo | 1982 |
Simple and sensitive assay employing stable reagents for quantification of plasminogen activator.
Topics: Animals; Caseins; Female; Fibrinolysis; Humans; Macrophage Activation; Methylcholanthrene; Mice; Neo | 1981 |
Induction of squamous cell carcinoma in human bronchi transplanted into nude mice.
Topics: Adult; Animals; Bronchi; Bronchial Neoplasms; Carcinoma, Squamous Cell; Female; Humans; Hyperplasia; | 1980 |
Specific organ gene transfer in vivo by regional organ perfusion with herpes viral amplicon vectors: implications for local gene therapy.
Topics: Animals; beta-Galactosidase; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Humans; Lun | 2001 |
Inhibition of chemical carcinogenesis by berberine in rats and mice.
Topics: Alkylating Agents; Animals; Berberine; Cell Transformation, Neoplastic; Diethylnitrosamine; Dose-Res | 2001 |
Protective effect of Picroliv, the active constituent of Picrorhiza kurroa, against chemical carcinogenesis in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Cinnamates; Croton | 2001 |
Temperature dependence in proliferation of tetraploid Meth-A cells in comparison with the parent diploid cells.
Topics: Aneuploidy; Animals; Cell Division; Cell Size; Diploidy; Electron Spin Resonance Spectroscopy; Flow | 2001 |
Immunization with heat shock protein 70 from methylcholanthrene-induced sarcomas induces tumor protection correlating with in vitro T cell responses.
Topics: Animals; Blotting, Western; Cancer Vaccines; Carcinogens; Dose-Response Relationship, Drug; Electrop | 2002 |
On the significance of sex hormones in producing experimental prostate tumor in the rat.
Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinoma, Squamous Cell; Male; Methylcholanthrene; Neoplasm Meta | 1977 |
In vitro studies on cell-mediated cytotoxicity by means of a terminal labeling technique.
Topics: Animals; Cell Count; Chromium Radioisotopes; Cytotoxicity Tests, Immunologic; Immunity, Cellular; Is | 1975 |
Studies on rat complement. II. Complement level in experimental tumor in rats.
Topics: Animals; Carcinoma, Hepatocellular; Complement C3; Complement C4; Complement System Proteins; Coryne | 1975 |
Murine leukemia virus in chemically-induced sarcomas as detected by XC plaque formation.
Topics: Animals; Leukemia Virus, Murine; Methylcholanthrene; Mice; Sarcoma; Viral Plaque Assay | 1978 |
Surface proteins and fibrinolytic activity of cultured mammalian cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Carcinoma; Cell Line; Cell Membrane; Cell Transformation, Neoplast | 1976 |
[The type specific antigen of Gross leukemia virus in tumors and normal tissues and its identification by immunodiffusion methods].
Topics: 9,10-Dimethyl-1,2-benzanthracene; AKR murine leukemia virus; Animals; Antigens, Viral; Leukemia, Exp | 1976 |
Study of a microassay for the quantitation of cytotoxic antitumor antibody, using 125I-iododeoxyuridine as a target cell label; detection of a static effect on cell DNA synthesis.
Topics: Animals; Antibodies, Neoplasm; Cell Survival; Culture Techniques; Cytotoxicity Tests, Immunologic; D | 1976 |
A novel approach to the generation and identification of experimental hepatic metastases in a murine model.
Topics: Adenocarcinoma; Animals; Cyclophosphamide; Dimethylhydrazines; Disease Models, Animal; DNA, Recombin | 1986 |
Elevated energy expenditure in hepatocytes from tumor-bearing rats.
Topics: Animals; Energy Metabolism; Lactates; Liver; Male; Methylcholanthrene; Neoplasm Transplantation; Oxy | 1985 |
The heparin binding proteins of sarcoma induced by methylcholantrene in rats.
Topics: Animals; Carrier Proteins; Heparin; Male; Methylcholanthrene; Osmolar Concentration; Rats; Rats, Inb | 1985 |
Breast cancer prevention by supplemental vitamin E.
Topics: Breast Neoplasms; Disease Models, Animal; Female; Fibrocystic Breast Disease; Food, Fortified; Human | 1985 |
Search for common antigenicities among twenty-five sarcomas induced by methylcholanthrene.
Topics: Animals; Antigens; Epitopes; Female; Immunization; Methylcholanthrene; Mice; Sarcoma; Statistics as | 1970 |
Models of human disease in inbred Syrian hamsters.
Topics: Adenocarcinoma; Animals; Benz(a)Anthracenes; Benzopyrenes; Bronchial Neoplasms; Cricetinae; Disease | 1972 |
Rejection of tumor cells in vitro.
Topics: Animals; Antigens, Neoplasm; Cell Line; Cells, Cultured; Culture Media; Cytotoxicity Tests, Immunolo | 1973 |
Letter: Methyl-cholanthrene-induced sarcomata in mice after immunisation with Corynebacterium parvum plus syngeneic subcellular membrane fractions.
Topics: Animals; Bacterial Vaccines; Cell Transformation, Neoplastic; Liver Extracts; Male; Methylcholanthre | 1974 |
Experimental metastasizing in syngeneic and autochthonous tumour-host systems.
Topics: Animals; Benzopyrenes; Cell Transformation, Neoplastic; Disease Models, Animal; Graft vs Host Reacti | 1972 |
The influence of hostsplenectomy on the tumour allograft-promoting effectiveness of antilymphocyte serum.
Topics: Animals; Antigens, Neoplasm; Antilymphocyte Serum; Graft vs Host Reaction; Immunosuppression Therapy | 1973 |
[Study of prostatic carcinogenesis, using 20-methyl-cholanthrene in albino rats].
Topics: Adenocarcinoma; Adrenocorticotropic Hormone; Animals; Carcinoma, Squamous Cell; Hormones; Male; Meth | 1968 |
C-type RNA tumour virus genome expression in wild house mice.
Topics: Adenoma; Animals; Antigens; Antigens, Neoplasm; Carcinoma; Carcinoma, Squamous Cell; Complement Fixa | 1971 |
Inhibition of chemical carcinogenesis by viral vaccines.
Topics: Animals; Animals, Newborn; Antigens, Viral; Carcinogens; Complement Fixation Tests; Female; Immuniza | 1972 |
Embryonic antigen expression in chemically induced rat hepatomas and sarcomas.
Topics: Animals; Antigen-Antibody Reactions; Antigens, Neoplasm; Carcinoembryonic Antigen; Carcinoma, Hepato | 1972 |
Lymphomas in BALB-c mice inoculated with supernatants from chemically induced sarcomas.
Topics: Animals; Gammaretrovirus; Lymphoma; Methylcholanthrene; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; | 1973 |
Suppression of chemically induced pulmonary tumors by treatment of strain A mice with murine sarcoma virus.
Topics: Adenoma; Animals; Female; Gammaretrovirus; Lung Neoplasms; Male; Methylcholanthrene; Mice; Mice, Inb | 1974 |
An analysis of variables affecting the measurement of tumor immunity in vitro with 125I-iododeoxyuridine-labelled target cells. Studies of immunity to primary Moloney sarcomas.
Topics: Animals; Antigen-Antibody Reactions; Cell Division; Cell Line; Cytotoxicity Tests, Immunologic; Deox | 1974 |
[Experimental ovarian tumor. (2). Experimental ovarian tumor in rats treated with a chemical carcinogen, 9, 10-dimethyl-1, 2-benzanthracene].
Topics: Adenocarcinoma; Animals; Benz(a)Anthracenes; Carcinogens; Cystadenoma; Female; Granulosa Cell Tumor; | 1974 |
Host immunity to growing sarcomas: tumor-specific serum inhibition of tumor-specific cellular immunity.
Topics: Animals; Antibody Specificity; Antigens, Neoplasm; Carcinoma; Cell Line; Female; Fibroblasts; Guinea | 1973 |
[Variability of cell elements of myogenic and connective tissue tumors in rats].
Topics: Animals; Carcinogens; Cobalt; Mesenchymoma; Methylcholanthrene; Neoplasm Transplantation; Neoplasms, | 1972 |
BCG immunotherapy of pulmonary growths from intravenously transferred rat tumour cells.
Topics: Adjuvants, Immunologic; Animals; BCG Vaccine; Immunotherapy; Injections, Intravenous; Lung Neoplasms | 1973 |
Relationships between aryl hydrocarbon hydroxylase inducibility and sensitivity to chemically induced subcutaneous sarcomas in various strains of mice.
Topics: Animals; Antigens, Viral; Complement Fixation Tests; Enzyme Induction; Hydrocarbons; Methylcholanthr | 1973 |
Cell proliferation patterns in an autogenous rat sarcoma.
Topics: Analysis of Variance; Animals; Autoradiography; Carbon Isotopes; Cell Division; Connective Tissue Ce | 1973 |
Proceedings: Sarcoma cells as a blastocyst analogue in the mouse uterus.
Topics: Animals; Blastocyst; Decidua; Embryo Implantation; Female; Methylcholanthrene; Mice; Neoplasm Transp | 1974 |
Immune cytolysis of murine tumor cells mediated by xenogeneic "immune" RNA.
Topics: Animals; Antigen-Antibody Reactions; Antilymphocyte Serum; Benzopyrenes; Centrifugation, Density Gra | 1974 |
The activity of certain respiratory enzymes in experimental brain tumors in mice.
Topics: Animals; Astrocytoma; Brain Neoplasms; Ependymoma; Fibrosarcoma; Glioma; Glucosephosphate Dehydrogen | 1972 |
Inherited susceptibility of inbred strains of Syrian hamsters to induction of subcutaneous sarcomas and mammary and gastrointestinal carcinomas by subcutaneous and gastric administration of polynuclear hydrocarbons.
Topics: Adrenal Glands; Animals; Benz(a)Anthracenes; Benzopyrenes; Carcinogens; Cricetinae; Female; Gastroin | 1972 |
[Experimental pulmonary cancer].
Topics: Adenocarcinoma; Animals; Carcinoma, Squamous Cell; Cricetinae; Lung Neoplasms; Methylcholanthrene; M | 1972 |
Methylcholanthrene-induced endometrial carcinoma in mice and rats: a histological and ultrastructural study.
Topics: Adenocarcinoma; Animals; Carcinoma, Squamous Cell; Carcinosarcoma; Cell Nucleus; Cytoplasm; Endometr | 1971 |
Production of experimental brain tumours by 20-methylcholanthrene in Swiss mice.
Topics: Anesthesia; Animals; Astrocytoma; Body Weight; Brain Neoplasms; Female; Glioma; Male; Methylcholanth | 1969 |
Comparison of tumor immunity after complete excision, cryonecrosis, and in the presence of persistent tumor.
Topics: Adenocarcinoma; Animals; Antigens; Antigens, Neoplasm; Cryosurgery; Mammary Neoplasms, Experimental; | 1970 |
Diurnal variation in susceptibility of mouse skin to the tumorigenic action of methylcholanthrene.
Topics: Animals; Carcinoma; Circadian Rhythm; DNA; Female; Male; Methylcholanthrene; Mice; Mitosis; Papillom | 1970 |
Demonstration of cellular antigens on sarcoma cells by an indirect 125-I-labeled antibody technique.
Topics: Animals; Antibodies; Antigen-Antibody Reactions; Antigens; Chromium Isotopes; Female; Friend murine | 1968 |
Vagotomy, gastroenterostomy and experimental gastic cancer.
Topics: Adenocarcinoma; Animals; Carcinoma, Squamous Cell; Gastroenterostomy; Hydrochloric Acid; Methylchola | 1968 |
Burn scar malignancy in a possible depressed immunologic setting.
Topics: Animals; Burns; Cicatrix; Methylcholanthrene; Rats; Sarcoma; Skin Neoplasms; Splenectomy; Splenic Ar | 1968 |
The sensitizing carcinogenic effect of small doses of carcinogen.
Topics: Animals; Benz(a)Anthracenes; Benzopyrenes; Carcinogens; Drug Hypersensitivity; Injections, Subcutane | 1968 |
Effect of parenteral steroids on induction of genital tumors in mice by 20-methylcholanthrene.
Topics: Adenocarcinoma; Animals; Carcinoma, Squamous Cell; Female; Genital Neoplasms, Female; Intrauterine D | 1969 |
The role of the regional lymph nodes in the immunity to a chemically induced sarcoma in C3H mice.
Topics: Amputation, Surgical; Animals; Female; Lymph Node Excision; Lymph Nodes; Methylcholanthrene; Mice; N | 1969 |
Intracellular potentials from experimental glial tumors.
Topics: Animals; Brain Neoplasms; Cell Membrane; Cerebral Cortex; Electrophysiology; Glioma; Methylcholanthr | 1966 |