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3-methylcholanthrene and Prostatic Neoplasms

3-methylcholanthrene has been researched along with Prostatic Neoplasms in 34 studies

Methylcholanthrene: A carcinogen that is often used in experimental cancer studies.
3-methylcholanthrene : A pentacyclic ortho- and peri-fused polycyclic arene consisting of a dihydrocyclopenta[ij]tetraphene ring system with a methyl substituent at the 3-position.

Prostatic Neoplasms: Tumors or cancer of the PROSTATE.

Research Excerpts

ExcerptRelevanceReference
"In a prostate cancer model, aggressive tumors arising in NKG2D-deficient mice expressed higher amounts of NKG2D ligands than did similar tumors in wild-type mice, suggesting an NKG2D-dependent immunoediting of tumors in this model."1.35NKG2D-deficient mice are defective in tumor surveillance in models of spontaneous malignancy. ( Cado, D; Choy, A; Gallardo, F; Greenberg, NM; Greenberg, NR; Guerra, N; Joncker, NT; Knoblaugh, S; Raulet, DH; Tan, YX; Xiong, N, 2008)
"Cadmium workers have been thought to be more likely to develop prostatic cancer."1.26Methyl cholanthrene and cadmium induced changes in rat prostate. ( Aughey, E; Scott, R, 1978)

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-199030 (88.24)18.7374
1990's1 (2.94)18.2507
2000's2 (5.88)29.6817
2010's1 (2.94)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sanada, N1
Gotoh, Y1
Shimazawa, R1
Klinge, CM1
Kizu, R1
DUNNING, WF1
CURTIS, MR1
SEGALOFF, A2
Chow, MT1
Sceneay, J1
Paget, C1
Wong, CS1
Duret, H1
Tschopp, J1
Möller, A1
Smyth, MJ1
LASNITZKI, I3
MIRAND, EA2
STAUBITZ, WJ2
KALLEN, B1
ROHL, L1
WOJEWSKI, A2
LASKA, A2
KRASON, S1
ROESSLER, R1
TAKENAKA, I2
STEWART, HL1
SNELL, KC1
MORRIS, HP1
HORNING, ES1
Guerra, N1
Tan, YX1
Joncker, NT1
Choy, A1
Gallardo, F1
Xiong, N1
Knoblaugh, S1
Cado, D1
Greenberg, NM1
Greenberg, NR1
Raulet, DH1
Kazuta, M3
Higuchi, M1
Rastogi, RB1
Agarwal, RA1
Jande, SS1
Singhal, RL1
Scott, R2
Aughey, E2
Jacobs, SC1
McLaughlin, AP1
Gittes, RF1
Gomaa, K1
Kraus, J1
Rosskopf, F1
Röper, H1
Franz, G1
Abdalla, AM1
Oliver, JA1
Mondal, S1
Embleton, MJ2
Marquardt, H1
Heidelberger, C3
Sahu, AB1
Sinha, D1
Mukerji, B1
Ronzoni, G1
Alquati, P1
Pola, P1
Alcini, E1
McLaughlin, I1
Cooper, TP1
Barham, RE1
Ansell, JS1
Oesch, F1
Gupta, SK1
Mathur, IS1
Kar, AB1
Kato, T1
Ishibe, T2
Fukushige, M2
Mizoguchi, M1
Chen, TT1

Reviews

1 review available for 3-methylcholanthrene and Prostatic Neoplasms

ArticleYear
Mammalian epoxide hydrases: inducible enzymes catalysing the inactivation of carcinogenic and cytotoxic metabolites derived from aromatic and olefinic compounds.
    Xenobiotica; the fate of foreign compounds in biological systems, 1973, Volume: 3, Issue:5

    Topics: Animals; Antimetabolites; Benz(a)Anthracenes; Binding Sites; Carcinogens; Enzyme Induction; Ethers,

1973

Other Studies

33 other studies available for 3-methylcholanthrene and Prostatic Neoplasms

ArticleYear
Repression of activated aryl hydrocarbon receptor-induced transcriptional activation by 5alpha-dihydrotestosterone in human prostate cancer LNCaP and human breast cancer T47D cells.
    Journal of pharmacological sciences, 2009, Volume: 109, Issue:3

    Topics: Androgens; Aryl Hydrocarbon Hydroxylases; Basic Helix-Loop-Helix Transcription Factors; Breast Neopl

2009
Methylcholanthrene squamous cell carcinoma of the rat prostate with skeletal metastases, and failure of the rat liver to respond to the carcinogen.
    Cancer research, 1946, Volume: 6

    Topics: Animals; Carcinogens; Carcinoma, Squamous Cell; Humans; Liver; Male; Methylcholanthrene; Neoplasms;

1946
NLRP3 suppresses NK cell-mediated responses to carcinogen-induced tumors and metastases.
    Cancer research, 2012, Nov-15, Volume: 72, Issue:22

    Topics: Adenocarcinoma; Animals; Carrier Proteins; CD11b Antigen; Chemokine CCL5; Chemokine CXCL9; Fibrosarc

2012
The influence of A hypervitaminosis on the effect of 20-methylcholanthrene on mouse prostate glands grown in vitro.
    British journal of cancer, 1955, Volume: 9, Issue:3

    Topics: Animals; Humans; In Vitro Techniques; Male; Methylcholanthrene; Mice; Neoplasms, Experimental; Prost

1955
Prostatic neoplasms of the Wistar rat induced with 20-methylcholantrene.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1956, Volume: 93, Issue:3

    Topics: Animals; Humans; Male; Methylcholanthrene; Neoplasms, Experimental; Prostatic Neoplasms; Rats; Rats,

1956
Prostatic neoplasms of the Wistar rat induced with 20-methylcholantrene.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1956, Volume: 93, Issue:3

    Topics: Animals; Humans; Male; Methylcholanthrene; Neoplasms, Experimental; Prostatic Neoplasms; Rats; Rats,

1956
Prostatic neoplasms of the Wistar rat induced with 20-methylcholantrene.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1956, Volume: 93, Issue:3

    Topics: Animals; Humans; Male; Methylcholanthrene; Neoplasms, Experimental; Prostatic Neoplasms; Rats; Rats,

1956
Prostatic neoplasms of the Wistar rat induced with 20-methylcholantrene.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1956, Volume: 93, Issue:3

    Topics: Animals; Humans; Male; Methylcholanthrene; Neoplasms, Experimental; Prostatic Neoplasms; Rats; Rats,

1956
Tissue culture studies on a rat prostatic cancer, induced with 20-methylcholanthrene.
    Acta pathologica et microbiologica Scandinavica, 1960, Volume: 50

    Topics: Animals; Humans; Male; Methylcholanthrene; Prostatic Neoplasms; Rats

1960
DISCUSSION ON EXPERIMENTAL TUMORS; OBSERVATIONS ON A SQUAMOUS CELL CARCINOMA.
    National Cancer Institute monograph, 1963, Volume: 12

    Topics: Adenocarcinoma; Adrenal Cortex Hormones; Androgens; Carcinoma, Squamous Cell; Dexamethasone; Estradi

1963
EXPERIMENTAL CANCER OF THE PROSTATE.
    Urologia internationalis, 1964, Volume: 17

    Topics: Carcinoma, Squamous Cell; Castration; Estradiol; Humans; Male; Methylcholanthrene; Neoplasms; Prosta

1964
EXPERIMENTAL TUMORS OF THE UROGENITAL SYSTEM.
    The Journal of urology, 1964, Volume: 92

    Topics: Animals; Castration; Humans; Kidney Neoplasms; Male; Methylcholanthrene; Neoplasms; Neoplasms, Exper

1964
[EXPERIMENTAL STUDIES OF PROSTATIC TUMORS. I. PRODUCTION OF THE PROSTATIC TUMOR OF RAT WITH 20-METHYLCHOLANTHRENE].
    Hinyokika kiyo. Acta urologica Japonica, 1964, Volume: 10

    Topics: Humans; Male; Methylcholanthrene; Pharmacology; Prostatic Neoplasms; Rats; Research; Toxicology

1964
(THE COMBINED EFFECT OF 3-METHYLCHOLANTHRENE AND N,N'-2,7-FLUORENYLENEBISACETMIDE ON THE INDUCTION OF CANCER OF THE GLANDULAR STOMACH OF THE RAT.)
    Journal of the National Cancer Institute, 1965, Volume: 34

    Topics: Abdominal Neoplasms; Abdominal Wall; Atrophy; Carcinogens; Ethmoid Bone; Female; Humans; Inflammatio

1965
Precancerous changes induced by 20-methylcholanthrene in mouse prostates grown in vitro.
    British journal of cancer, 1951, Volume: 5, Issue:3

    Topics: Animals; Carcinogens; Humans; In Vitro Techniques; Male; Methylcholanthrene; Mice; Prostatic Neoplas

1951
The local action of 20-methylcholanthrene and sex hormones on prostatic grafts.
    British journal of cancer, 1952, Volume: 6, Issue:1

    Topics: Gonadal Steroid Hormones; Humans; Male; Methylcholanthrene; Prostatic Neoplasms

1952
NKG2D-deficient mice are defective in tumor surveillance in models of spontaneous malignancy.
    Immunity, 2008, Volume: 28, Issue:4

    Topics: Adenocarcinoma; Animals; Benz(a)Anthracenes; Disease Models, Animal; Female; Fibrosarcoma; Immunolog

2008
[DNA metabolism of prostate. II. DNA metabolism of experimental prostatic tumors].
    Hinyokika kiyo. Acta urologica Japonica, 1966, Volume: 12, Issue:3

    Topics: Animals; Autoradiography; DNA; Male; Methylcholanthrene; Neoplasms, Experimental; Prostatic Neoplasm

1966
On the significance of sex hormones in producing experimental prostate tumor in the rat.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1977, Issue:60

    Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinoma, Squamous Cell; Male; Methylcholanthrene; Neoplasm Meta

1977
Effect of testosterone and 6-hydroxydopamine treatment on the metabolism of catecholamine and 5-hydroxytryptamine in methylcholanthrene-induced prostate carcinoma of rats.
    Canadian journal of physiology and pharmacology, 1979, Volume: 57, Issue:6

    Topics: Animals; Carcinoma, Squamous Cell; Catecholamines; Hydroxydopamines; Male; Methylcholanthrene; Neopl

1979
Methyl cholanthrene and cadmium induced changes in rat prostate.
    British journal of urology, 1978, Volume: 50, Issue:1

    Topics: Animals; Cadmium; Male; Methylcholanthrene; Prostate; Prostatic Neoplasms; Rats

1978
Effects of immunosuppression on the rejection of methylcholanthrene tumor isografts.
    Journal of surgical oncology, 1977, Volume: 9, Issue:4

    Topics: Animals; Antigens, Neoplasm; Azathioprine; Carcinoma, Squamous Cell; Graft Rejection; Immunosuppress

1977
Reversal of methylcholanthrene-induced changes in mouse prostates in vitro by retinoic acid and its analogues.
    British journal of cancer, 1976, Volume: 34, Issue:3

    Topics: Animals; DNA; Hyperplasia; In Vitro Techniques; Male; Metaplasia; Methylcholanthrene; Mice; Mice, In

1976
Antitumour and immunological activity of a beta 1----3/1----6 glucan from Glomerella cingulata.
    Journal of cancer research and clinical oncology, 1992, Volume: 118, Issue:2

    Topics: Animals; Diethylstilbestrol; Drug Screening Assays, Antitumor; Fibrosarcoma; Glucans; Lymphocyte Act

1992
Prostatic carcinoma of human origin transplanted in the golden hamster.
    The Journal of urology, 1971, Volume: 106, Issue:4

    Topics: Animals; Cell Transformation, Neoplastic; Cricetinae; Humans; Injections, Subcutaneous; Isoenzymes;

1971
Production of variants of decreased malignancy and antigenicity from clones transformed in vitro by methylcholanthrene.
    International journal of cancer, 1971, Nov-15, Volume: 8, Issue:3

    Topics: Animals; Antigens; Antigens, Neoplasm; Ascitic Fluid; Cell Line; Chromosome Aberrations; Clone Cells

1971
Histochemical characterization of experimental prostate tumors in mice induced by testosterone and 20-methylcholanthrene.
    Indian journal of experimental biology, 1969, Volume: 7, Issue:1

    Topics: Acid Phosphatase; Alkaline Phosphatase; Animals; DNA, Neoplasm; Glycosaminoglycans; Histocytochemist

1969
[Study of prostatic carcinogenesis, using 20-methyl-cholanthrene in albino rats].
    Chirurgia e patologia sperimentale, 1968, Volume: 16, Issue:5

    Topics: Adenocarcinoma; Adrenocorticotropic Hormone; Animals; Carcinoma, Squamous Cell; Hormones; Male; Meth

1968
Fine structural changes in rat prostate 5 months after the experimental introduction of 20-methylcholanthrene.
    British journal of urology, 1974, Volume: 46, Issue:5

    Topics: Animals; Lysosomes; Male; Membranes; Methylcholanthrene; Microscopy, Electron; Mitochondria; Prostat

1974
Methylcholanthrene-induced adenocarcinoma of the prostate in rats.
    Surgical forum, 1974, Volume: 25, Issue:0

    Topics: Adenocarcinoma; Animals; Carcinoma, Squamous Cell; Male; Methylcholanthrene; Neoplasms, Experimental

1974
Antigenicity of clones of mouse prostate cells transformed in vitro.
    International journal of cancer, 1972, Jan-15, Volume: 9, Issue:1

    Topics: Animals; Antigens; Cell Transformation, Neoplastic; Clone Cells; Cross Reactions; Cytotoxicity Tests

1972
Chemical induction of prostatic tumours in random-bred rats.
    Indian journal of experimental biology, 1971, Volume: 9, Issue:3

    Topics: Adenocarcinoma; Animals; Carcinoma, Squamous Cell; Leiomyosarcoma; Male; Methylcholanthrene; Neoplas

1971
[DNA metabolism of prostate. 3. Effects of sexual hormones upon DNA metabolism in normal rat's prostatic gland and during development of experimental prostatic tumors].
    Hinyokika kiyo. Acta urologica Japonica, 1967, Volume: 13, Issue:1

    Topics: Animals; Autoradiography; DNA; Estradiol; Male; Methylcholanthrene; Neoplasms, Experimental; Prostat

1967
[Urological neoplasms and enzymes. I. Changes of LDH and ALP activities and LDH isozyme in experimental prostatic neoplasms in rat and effects of various hormones upon these enzyme activities].
    Hinyokika kiyo. Acta urologica Japonica, 1967, Volume: 13, Issue:4

    Topics: Alkaline Phosphatase; Animals; Gonadal Steroid Hormones; Isoenzymes; L-Lactate Dehydrogenase; Male;

1967
Hormonal effects on the enzyme activities of the prostate of rat during 20-methylcholanthrene carcinogenesis.
    Endocrinologia japonica, 1968, Volume: 15, Issue:2

    Topics: Alkaline Phosphatase; Animals; Estradiol; Isoenzymes; L-Lactate Dehydrogenase; Male; Methylcholanthr

1968
In vitro malignant transformation of cells derid from mouse prostate in the presence of 3-methylcholanthrene.
    Journal of the National Cancer Institute, 1969, Volume: 42, Issue:6

    Topics: Animals; Cattle; Cell Division; Cell Line; Cell Transformation, Neoplastic; Chromosomes; Cricetinae;

1969