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3-methylcholanthrene and Plasmacytoma

3-methylcholanthrene has been researched along with Plasmacytoma in 8 studies

Methylcholanthrene: A carcinogen that is often used in experimental cancer studies.
3-methylcholanthrene : A pentacyclic ortho- and peri-fused polycyclic arene consisting of a dihydrocyclopenta[ij]tetraphene ring system with a methyl substituent at the 3-position.

Plasmacytoma: Any discrete, presumably solitary, mass of neoplastic PLASMA CELLS either in BONE MARROW or various extramedullary sites.

Research Excerpts

ExcerptRelevanceReference
"The ability of alpha-fetoprotein (AFP), derived from mouse amniotic fluid, to alter qualitative and quantitative characteristics of pristane-induced plasmacytomas and the carcinogenic action of 3-methylcholanthrene (MCA) and 7,12-dimethylbenz]a[-anthracene (DMBA) was studied and compared to analogous treatment with murine albumin and transferrin in BALB/c mice."3.66Accelerated plasmacytoma formation in mice treated with alpha-fetoprotein. ( Castles, JJ; Gershwin, ME; Makishima, R, 1980)
"Weanling BALB/c mice given injections of 300 micrograms concanavalin A (Con A) prior to and at frequent intervals after challenge with Moloney murine sarcoma virus (M-MuSV), 3-methylcholanthrene (MCA), or TEPC-15 plasmacytoma cells showed an enhancement of tumor induction or development."3.66Enhancement of experimental tumors in mice by treatment with concanavalin A. ( Ekstedt, RD, 1979)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19908 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gershwin, ME1
Castles, JJ1
Makishima, R1
Fujiwara, H1
Aoki, H1
Yoshioka, T1
Tomita, S1
Ikegami, R1
Hamaoka, T1
Friedman, FK1
Robinson, RC1
Park, SS1
Gelboin, HV1
Ting, CC1
Herberman, RB1
Ekstedt, RD1
Outzen, HC1
Custer, RP1
Eaton, GJ1
Prehn, RT1
Hines, DL1
Fish, F1
Yaakubovicz, M1
Witz, IP1

Reviews

1 review available for 3-methylcholanthrene and Plasmacytoma

ArticleYear
Humoral host defense mechanisms against tumors.
    International review of experimental pathology, 1976, Volume: 15

    Topics: Animals; Antigens; Antigens, Neoplasm; Antigens, Viral; Azo Compounds; Cytotoxicity Tests, Immunolog

1976

Other Studies

7 other studies available for 3-methylcholanthrene and Plasmacytoma

ArticleYear
Accelerated plasmacytoma formation in mice treated with alpha-fetoprotein.
    Journal of the National Cancer Institute, 1980, Volume: 64, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Albumins; alpha-Fetoproteins; Animals; Female; Immunoglobulins; Ma

1980
Establishment of a tumor-specific immunotherapy model utilizing TNP-reactive helper T cell activity and its application to the autochthonous tumor system.
    Journal of immunology (Baltimore, Md. : 1950), 1984, Volume: 133, Issue:1

    Topics: Animals; Cell Transformation, Neoplastic; Disease Models, Animal; Female; Fibrosarcoma; Haptens; Imm

1984
Monoclonal antibody-directed immunopurification and identification of cytochromes P-450.
    Biochemical and biophysical research communications, 1983, Nov-15, Volume: 116, Issue:3

    Topics: Animals; Antibodies, Monoclonal; Antigen-Antibody Complex; Cytochrome P-450 Enzyme System; Enzyme In

1983
Enhancement of experimental tumors in mice by treatment with concanavalin A.
    Journal of the National Cancer Institute, 1979, Volume: 63, Issue:4

    Topics: Animals; Concanavalin A; Immunosuppression Therapy; Male; Methylcholanthrene; Mice; Mice, Inbred BAL

1979
Spontaneous and induced tumor incidence in germfree "nude" mice.
    Journal of the Reticuloendothelial Society, 1975, Volume: 17, Issue:1

    Topics: Age Factors; Animals; Female; Genes, Recessive; Germ-Free Life; Heterozygote; Homozygote; Leukemia,

1975
Comparison of tumor-associated transplantation antigens of sublines of methylcholanthrene-induced murine tumors passaged separately in vivo for over a decade.
    Cancer research, 1986, Volume: 46, Issue:10

    Topics: Animals; Antigens, Neoplasm; Cell Line; Female; Fibrosarcoma; Histocompatibility Antigens; Immunizat

1986
Incorporation of 125-I-iododeoxyuridine into target cells as an assay for cell immunity.
    Journal of the National Cancer Institute, 1974, Volume: 53, Issue:6

    Topics: Animals; Cytotoxicity Tests, Immunologic; Idoxuridine; Immunity, Cellular; Immunization; Iodine Radi

1974