3-methylcholanthrene has been researched along with Metastase in 128 studies
Methylcholanthrene: A carcinogen that is often used in experimental cancer studies.
3-methylcholanthrene : A pentacyclic ortho- and peri-fused polycyclic arene consisting of a dihydrocyclopenta[ij]tetraphene ring system with a methyl substituent at the 3-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Long-term oral administration of sodium warfarin significantly reduced the incidence of spontaneous metastases in the lungs from 83 percent in controls to 8 percent in treated C57/BL/6N mice." | 7.64 | Warfarin treatment of mice bearing autochthonous tumors: effect on spontaneous metastases. ( Ketcham, AS; Ryan, JJ; Wexler, H, 1968) |
| "Cell lines from metastases and primary tumors were heterogeneous in tumorigenicity, growth rate, metastatic potential (spontaneous), and colonizing capacity (i." | 5.27 | Characterization of spontaneous metastases from autochthonous 3-methylcholanthrene-induced tumors. ( Bottazzi, B; Giavazzi, R; Mantovani, A; Taraboletti, G, 1986) |
| "We have used the murine 3-methylcholanthrene induced T10 fibrosarcoma tumor cell system originating in (C3II/en x C57BL/6)F1 mice (H-2b x H-2k) to elucidate the possible correlation between metastatic potential, expression of individual H-2 antigens and susceptibility to NK cells." | 4.78 | Resistance to NK and metastatic potential of fibrosarcoma cells is associated with products encoded by the H-2D region. ( Aboud, M; Gopas, J; Hämmerling, GJ; Har-Vardi, I; Rager-Zisman, B; Segal, S, 1991) |
| "A 3-Methylcholanthrene (MC)-induced fibrosarcoma and three of its clones were investigated for their metastatic potential in normal and tumor immune mice." | 3.67 | The effect of immunity on pulmonary metastasis of a methylcholanthrene-induced fibrosarcoma and three of its clones. ( McKhann, CF; Wang, N; Yu, S, 1984) |
| "Levamisole has been examined for its ability to control local growth and pulmonary metastases of transplanted rat tumours." | 3.65 | Levamisole treatment of local and metastatic growth of transplanted rat tumours. ( Baldwin, RW; Hopper, DG; Pimm, MV, 1975) |
| "Long-term oral administration of sodium warfarin significantly reduced the incidence of spontaneous metastases in the lungs from 83 percent in controls to 8 percent in treated C57/BL/6N mice." | 3.64 | Warfarin treatment of mice bearing autochthonous tumors: effect on spontaneous metastases. ( Ketcham, AS; Ryan, JJ; Wexler, H, 1968) |
| "Fibrosarcomas without metastasis were the only tumours observed in the MCA-treated quail, while quail treated with JM16 and MCA developed undifferentiated tumours, fibrosarcomas, lymphosarcomas or combinations with or without metastasis." | 1.36 | Role of Marek's disease herpesvirus in the induction of tumours in Japanese quail (Coturnix coturnix japonica) by methylcholanthrene. ( Blackmore, C; Mondal, SP; O'Connell, P; Schat, KA; Wakenell, PS, 2010) |
| "When injected i." | 1.28 | Fibrosarcoma cells transduced with the IL-6 gene exhibited reduced tumorigenicity, increased immunogenicity, and decreased metastatic potential. ( Blaese, RM; Brandt, S; Coale, MM; Levy, AT; Liotta, LA; Mullen, CA; Stetler-Stevenson, WG, 1992) |
| "Thus, the tumorigenic transformation of HUC resulted from the combined actions of SV40 and MCA." | 1.27 | Neoplastic transformation of SV40-immortalized human urinary tract epithelial cells by in vitro exposure to 3-methylcholanthrene. ( Christian, BJ; Loretz, LJ; Meisner, LF; Reznikoff, CA; Wu, SQ, 1988) |
| "The effectiveness of the treatment on metastasis was also shown by the prolongation of mean survival time in groups of mice which showed no local recurrence of tumors." | 1.27 | Therapeutic effects of PS-K and busulfan on the recurrent and metastatic diseases after the surgical removal of 3-methylcholanthrene-induced autochthonous tumors in C57BL/6 mice. ( Hosokawa, M; Kobayashi, H; Mizukoshi, T; Sugawara, M, 1985) |
| "Cell lines from metastases and primary tumors were heterogeneous in tumorigenicity, growth rate, metastatic potential (spontaneous), and colonizing capacity (i." | 1.27 | Characterization of spontaneous metastases from autochthonous 3-methylcholanthrene-induced tumors. ( Bottazzi, B; Giavazzi, R; Mantovani, A; Taraboletti, G, 1986) |
| "Spontaneous metastases from the same tumour transplanted to the tail did occur in the nude mice and were possibly facilitated by specifically sensitized spleen cells." | 1.26 | Transplantability and metastasibility of an MCA-induced sarcoma in nude mice. Influence of transfer of thymus cells and adoptive immunity. ( Boeryd, B; Suurküla, M, 1977) |
| "Induced thrombocytopenia has been found to decrease metastasis formation after intravenous tumour cell injection which emphasizes the importance of platelets in metastasis formation." | 1.26 | Metastasis formation after intravenous tumour cell injection in thrombocytopenic rats. ( Ivarsson, L, 1976) |
| "The spontaneous metastasis to lymph nodes and lungs was macroscopically found within several weeks after tumor transplantation." | 1.25 | Induction of metastasizing carcinoma in rats and their biological characteristics. ( Harada, Y, 1975) |
| "Early metastases to the lung was associated with low levels of tumor-specific immunogenicity and high levels of H-2 antigenicity." | 1.25 | Antigenic specificities on murine sarcoma cells. Reciprocal relationship between normal transplantation antigens (H-2) and tumor-specific immunogenicity. ( Haywood, GR; McKhann, CF, 1971) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 108 (84.38) | 18.7374 |
| 1990's | 12 (9.38) | 18.2507 |
| 2000's | 6 (4.69) | 29.6817 |
| 2010's | 2 (1.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wakenell, PS | 1 |
| O'Connell, P | 1 |
| Blackmore, C | 1 |
| Mondal, SP | 1 |
| Schat, KA | 1 |
| Chow, MT | 1 |
| Sceneay, J | 1 |
| Paget, C | 1 |
| Wong, CS | 1 |
| Duret, H | 1 |
| Tschopp, J | 1 |
| Möller, A | 1 |
| Smyth, MJ | 3 |
| ZALDIVAR, RS | 1 |
| GHOSE, T | 1 |
| KIKUCHI, K | 1 |
| TSUJI, Y | 1 |
| ITAKURA, K | 1 |
| KATAGIRI, H | 1 |
| INGALL, JR | 1 |
| WEXLER, H | 6 |
| MINTON, JP | 1 |
| KETCHAM, AS | 7 |
| GARDNER, B | 1 |
| EISENBERG, E | 1 |
| SCHMIDT, DM | 1 |
| Apte, RN | 1 |
| Krelin, Y | 1 |
| Song, X | 1 |
| Dotan, S | 1 |
| Recih, E | 1 |
| Elkabets, M | 1 |
| Carmi, Y | 1 |
| Dvorkin, T | 1 |
| White, RM | 1 |
| Gayvoronsky, L | 1 |
| Segal, S | 3 |
| Voronov, E | 1 |
| Watanabe, R | 1 |
| Arkhipov, GN | 1 |
| Kim, U | 6 |
| Yu, S | 1 |
| Wang, N | 1 |
| McKhann, CF | 2 |
| Kahan, BD | 1 |
| Pellis, NR | 1 |
| LeGrue, SJ | 1 |
| Tanaka, T | 1 |
| Hamuro, J | 1 |
| Takatsuki, F | 1 |
| Suga, T | 1 |
| Kikuchi, T | 1 |
| Suzuki, M | 1 |
| Bezault, J | 1 |
| Bhimani, R | 1 |
| Wiprovnick, J | 1 |
| Furmanski, P | 2 |
| Takayama, T | 1 |
| Mogi, Y | 2 |
| Kogawa, K | 2 |
| Yoshizaki, N | 1 |
| Muramatsu, H | 1 |
| Koike, K | 1 |
| Semba, K | 1 |
| Yamamoto, T | 1 |
| Niitsu, Y | 2 |
| Kashida, T | 1 |
| Narasaki, N | 1 |
| Tsujihara, K | 1 |
| Naito, K | 1 |
| Takeyama, S | 1 |
| Wang, JM | 1 |
| Chertov, O | 1 |
| Proost, P | 1 |
| Li, JJ | 1 |
| Menton, P | 1 |
| Xu, L | 1 |
| Sozzani, S | 1 |
| Mantovani, A | 2 |
| Gong, W | 1 |
| Schirrmacher, V | 2 |
| Van Damme, J | 1 |
| Oppenheim, JJ | 1 |
| Street, SE | 1 |
| Cretney, E | 2 |
| Tatsuka, M | 1 |
| Maeda, M | 1 |
| Ota, T | 1 |
| Takeda, K | 1 |
| Yagita, H | 1 |
| Glaccum, M | 1 |
| Peschon, JJ | 1 |
| Chen, H | 1 |
| Diao, L | 1 |
| Chen, D | 1 |
| Li, H | 1 |
| Liu, M | 1 |
| Hashimoto, S | 1 |
| Sueishi, K | 1 |
| Higuchi, M | 1 |
| Sindelar, WF | 2 |
| Tralka, TS | 1 |
| Harada, Y | 2 |
| Ghosh, SK | 1 |
| Grossberg, AL | 1 |
| Pressman, D | 1 |
| Lundy, J | 1 |
| Lovett, EJ | 1 |
| Wolinsky, SM | 1 |
| Conran, P | 1 |
| Shantz, G | 1 |
| Adams, RA | 1 |
| Homburger, F | 1 |
| Russfield, AB | 1 |
| Soto, E | 1 |
| Lupulescu, A | 1 |
| McBride, WH | 1 |
| Tuach, S | 1 |
| Marmion, BP | 1 |
| Gericke, D | 1 |
| Bernacki, RJ | 1 |
| Boeryd, B | 10 |
| Suurküla, M | 4 |
| Baldwin, RW | 3 |
| Hopper, DG | 2 |
| Pimm, MV | 3 |
| Fisher, ER | 3 |
| Shoemaker, RH | 1 |
| Palekar, AS | 1 |
| Wood, GW | 1 |
| Gillespie, GY | 1 |
| Ivarsson, L | 1 |
| Suit, HD | 1 |
| Sedlacek, R | 1 |
| Wagner, M | 1 |
| Orsi, L | 1 |
| Silobrcic, V | 1 |
| Rothman, KJ | 1 |
| Reuber, MD | 1 |
| Mullen, CA | 1 |
| Coale, MM | 1 |
| Levy, AT | 1 |
| Stetler-Stevenson, WG | 1 |
| Liotta, LA | 1 |
| Brandt, S | 1 |
| Blaese, RM | 1 |
| Takada, T | 1 |
| Suzuki, S | 1 |
| Sugawara, Y | 1 |
| Kominami, R | 1 |
| Arakawa, M | 1 |
| Niwa, O | 1 |
| Yokoro, K | 1 |
| Minato, K | 1 |
| Manabe, T | 1 |
| Okuyama, N | 1 |
| Sasaki, Y | 1 |
| Nakagawa, K | 1 |
| Saijo, N | 1 |
| Rager-Zisman, B | 1 |
| Aboud, M | 1 |
| Gopas, J | 1 |
| Har-Vardi, I | 1 |
| Hämmerling, GJ | 2 |
| Algarra, I | 1 |
| Gaforio, JJ | 1 |
| Garrido, A | 1 |
| Mialdea, MJ | 1 |
| Pérez, M | 1 |
| Garrido, F | 1 |
| Mohanty, D | 1 |
| Hilgard, P | 1 |
| Alexander, P | 3 |
| Fortuna, MB | 1 |
| Dewey, MJ | 1 |
| Bandlow, G | 1 |
| Härtl, R | 1 |
| Frid, IA | 1 |
| Sapov, IA | 1 |
| Katyshev, AV | 1 |
| Lupanov, AI | 1 |
| Rudakov, VF | 1 |
| Semiachkina, SO | 1 |
| Shul'ga, NI | 1 |
| Reznikoff, CA | 1 |
| Loretz, LJ | 1 |
| Christian, BJ | 1 |
| Wu, SQ | 1 |
| Meisner, LF | 1 |
| Katenkamp, D | 1 |
| Kosmehl, H | 1 |
| Langbein, L | 1 |
| Alon, Y | 1 |
| Bar-Eli, M | 1 |
| Nagashima, A | 1 |
| Yasumoto, K | 1 |
| Nakahashi, H | 1 |
| Furukawa, T | 1 |
| Inokuchi, K | 1 |
| Nomoto, K | 1 |
| Hagmar, B | 8 |
| Ryd, W | 1 |
| Hosokawa, M | 1 |
| Mizukoshi, T | 1 |
| Sugawara, M | 1 |
| Kobayashi, H | 1 |
| Bottazzi, B | 1 |
| Taraboletti, G | 1 |
| Giavazzi, R | 1 |
| Viksler, VKh | 1 |
| Iaroslavtseva, OA | 1 |
| Lavroskiĭ, VA | 1 |
| McLaughlin, AP | 1 |
| Gittes, RF | 1 |
| Arnold, W | 2 |
| Graffi, A | 2 |
| Peterson, HI | 2 |
| Rudenstam, CM | 5 |
| Orme, SK | 1 |
| Krüger, G | 1 |
| Chopra, H | 1 |
| Taylor, DJ | 1 |
| Schreiber, H | 1 |
| Nettesheim, P | 2 |
| Martin, DH | 1 |
| Proctor, JW | 2 |
| Arita, H | 1 |
| Kawanami, J | 1 |
| Milas, L | 3 |
| Gutterman, JU | 1 |
| Basic, I | 1 |
| Hunter, N | 2 |
| Mavligit, GM | 1 |
| Hersh, EM | 1 |
| Withers, HR | 2 |
| Weiss, L | 1 |
| Glaves, D | 1 |
| Waite, DA | 1 |
| Simmons, RL | 1 |
| Rios, A | 1 |
| McCredie, JA | 1 |
| Inch, WR | 1 |
| Cowie, HC | 1 |
| Chretien, PB | 2 |
| Andrews, EJ | 1 |
| Kjartansson, I | 1 |
| Appelgren, L | 1 |
| Rosengren, B | 1 |
| Lewis, DH | 1 |
| Mujagic, H | 1 |
| Mason, K | 1 |
| Turusov, VS | 1 |
| Breslow, NE | 1 |
| Tomatis, L | 1 |
| Faraci, RP | 1 |
| Blumenthal, HT | 1 |
| Rogers, JB | 1 |
| Fisher, B | 2 |
| Soliman, O | 2 |
| Ishidate, M | 1 |
| Watanabe, M | 1 |
| Odashima, S | 1 |
| Hirao, F | 2 |
| Fujisawa, T | 2 |
| Tsubura, E | 2 |
| Yamamura, Y | 2 |
| Sugarbaker, EV | 1 |
| Cohen, AM | 1 |
| Godrick, EA | 1 |
| Michaelson, JS | 1 |
| Vanwijck, R | 1 |
| Wilson, RE | 1 |
| Hallgren, B | 1 |
| Ställberg, G | 1 |
| Tokuoka, S | 1 |
| Kimura, K | 1 |
| Hammons, AS | 1 |
| Ashraf, M | 1 |
| Zaman, H | 1 |
| Sirsat, SM | 1 |
| Shanbhag, UV | 1 |
| Krieg, K | 2 |
| Norrby, K | 2 |
| Rosenau, W | 1 |
| Domellöf, L | 1 |
| Kapila, K | 1 |
| Smith, C | 1 |
| Rubin, AA | 1 |
| Haywood, GR | 1 |
| Vaage, J | 1 |
| Chen, K | 1 |
| Merrick, S | 1 |
| Kuschner, M | 1 |
| Ryan, JJ | 1 |
| Akamatsu, Y | 1 |
| Maltzeff, N | 1 |
| Ito, N | 1 |
| Hiasa, Y | 1 |
| Konishi, Y | 1 |
| Marugami, M | 1 |
| Poel, WE | 1 |
| Mellgren, J | 1 |
| Bartholdsson, E | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Neoadjuvant Nivolumab, or Nivolumab in Combination With Ipilimumab, in Resectable Non-Small-Cell Lung Cancer.[NCT02259621] | Phase 2 | 45 participants (Anticipated) | Interventional | 2014-09-30 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for 3-methylcholanthrene and Metastase
| Article | Year |
|---|---|
Effects of micro-environment- and malignant cell-derived interleukin-1 in carcinogenesis, tumour invasiveness and tumour-host interactions.
Topics: Animals; Carcinogens; Humans; Inflammation; Interleukin-1; Methylcholanthrene; Mice; Models, Biologi | 2006 |
[Basic research on lung cancer].
Topics: Animals; Diethylnitrosamine; Disease Models, Animal; Genes, Tumor Suppressor; Growth Substances; His | 2002 |
Resistance to NK and metastatic potential of fibrosarcoma cells is associated with products encoded by the H-2D region.
Topics: Animals; Antigens, Neoplasm; Base Sequence; Cytotoxicity, Immunologic; Fibrosarcoma; H-2 Antigens; H | 1991 |
Neuraminidase treated cells and their role in cancer immunotherapy.
Topics: Adenocarcinoma; Animals; Antigens, Neoplasm; BCG Vaccine; Female; Fibrosarcoma; Immunotherapy; Mamma | 1973 |
Spontaneous and induced tumors in the guinea pig, with special reference to the factor of age.
Topics: Aging; Animals; Chondrosarcoma; Fibrosarcoma; Guinea Pigs; Methylcholanthrene; Myxosarcoma; Neoplasm | 1967 |
123 other studies available for 3-methylcholanthrene and Metastase
| Article | Year |
|---|---|
Role of Marek's disease herpesvirus in the induction of tumours in Japanese quail (Coturnix coturnix japonica) by methylcholanthrene.
Topics: Animals; Coturnix; DNA Primers; DNA, Neoplasm; Fibrosarcoma; Lymphoma, Non-Hodgkin; Mardivirus; Mare | 2010 |
NLRP3 suppresses NK cell-mediated responses to carcinogen-induced tumors and metastases.
Topics: Adenocarcinoma; Animals; Carrier Proteins; CD11b Antigen; Chemokine CCL5; Chemokine CXCL9; Fibrosarc | 2012 |
Cancer research in Chile.
Topics: Antineoplastic Agents; Chile; Hexestrol; Lung Neoplasms; Mechlorethamine; Methylcholanthrene; Neopla | 1962 |
THE EFFECT OF CORTISONE ON CARCINOGENESIS AND METASTATIC SPREAD OF AUTOCHTHONOUS TUMORS.
Topics: Adenocarcinoma; Animals; Carcinogenesis; Cortisone; Fibrosarcoma; Lung Neoplasms; Methylcholanthrene | 1963 |
A CASE OF METASTASES OF GASTRIC CANCER TO HYPERNEPHROMA AND ITS METASTATIC FOCI.
Topics: Adenocarcinoma; Carcinoma, Hepatocellular; Carcinoma, Renal Cell; Kidney Neoplasms; Liver Neoplasms; | 1964 |
A MODEL FOR THE STUDY OF EXPERIMENTAL BONE METASTASES.
Topics: Bone Neoplasms; Femoral Neoplasms; Fibrosarcoma; Methylcholanthrene; Neoplasm Metastasis; Neoplasm T | 1964 |
A COMPARISON OF SURVIVAL TIME AND EXTENT OF TUMOR METASTASES IN MICE WITH TRANSPLANTED, INDUCED AND SPONTANEOUS TUMORS.
Topics: Animals; Carcinogens; Ethiodized Oil; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Me | 1965 |
FAILURE OF OSTEOLYTIC AGENTS TO INDUCE SKELETAL METASTASES IN RATS WITH SARCOMA.
Topics: Animals; Bone Neoplasms; Carcinogens; Cholecalciferol; Injections, Subcutaneous; Methylcholanthrene; | 1965 |
Pathology of bone sarcoma induced by 20-methylcholanthrene.
Topics: Animals; Female; Fibrosarcoma; Male; Methylcholanthrene; Neoplasm Metastasis; Neoplasm Transplantati | 1966 |
Induction of cancer of the glandular stomach in rats by 20-methylcholanthrene.
Topics: Adenocarcinoma; Animals; Ephedrine; Methylcholanthrene; Neoplasm Metastasis; Neoplasms, Experimental | 1967 |
Metastatic patterns and properties of tumor cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Line; Female; Mammary Neoplasms, Experimental; Methy | 1984 |
The effect of immunity on pulmonary metastasis of a methylcholanthrene-induced fibrosarcoma and three of its clones.
Topics: Animals; Antigens, Neoplasm; Chromosome Aberrations; Clone Cells; Fibrosarcoma; Lung Neoplasms; Meth | 1984 |
Immunotherapeutic effects of tumor-specific transplantation antigens released by 1-butanol.
Topics: Animals; Antigens, Neoplasm; Butanols; Cyclophosphamide; Drug Therapy, Combination; Female; Histocom | 1982 |
Synergistic antimetastatic effects of lentinan and interleukin 2 with pre- and post-operative treatments.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; CD4-Positive T-Lymphocytes; CD8-Positive T- | 1994 |
Human lactoferrin inhibits growth of solid tumors and development of experimental metastases in mice.
Topics: 3T3 Cells; Animals; Cell Division; Female; Fibroma; Humans; Lactoferrin; Methylcholanthrene; Mice; M | 1994 |
A role for the fyn oncogene in metastasis of methylcholanthrene-induced fibrosarcoma A cells.
Topics: Animals; Fibrosarcoma; Gene Expression Regulation, Neoplastic; Methylcholanthrene; Mice; Mice, Inbre | 1993 |
Augmentation of sinecomitant immunity in mice by gamma-(9H-purine-6-yl)thiomethyl L-glutamate (6-MPG), a water-soluble derivative of 6-mercaptopurine.
Topics: Animals; Antineoplastic Agents; Cell Transplantation; Immunity, Cellular; Male; Mercaptopurine; Meth | 1998 |
Purification and identification of chemokines potentially involved in kidney-specific metastasis by a murine lymphoma variant: induction of migration and NFkappaB activation.
Topics: Animals; Cell Adhesion Molecules; Chemokine CCL2; Chemokine CCL5; Chemokines, CC; Chemotaxis, Leukoc | 1998 |
Perforin and interferon-gamma activities independently control tumor initiation, growth, and metastasis.
Topics: Animals; Antineoplastic Agents; Cell Division; Cell Transformation, Neoplastic; Cytotoxicity Tests, | 2001 |
Anticarcinogenic effect and enhancement of metastatic potential of BALB/c 3T3 cells by ginsenoside Rh(2).
Topics: 3T3 Cells; Animals; Anticarcinogenic Agents; Apoptosis; CDC2-CDC28 Kinases; Cell Division; Cell Line | 2001 |
Increased susceptibility to tumor initiation and metastasis in TNF-related apoptosis-inducing ligand-deficient mice.
Topics: Adenocarcinoma; Animals; Apoptosis Regulatory Proteins; Cell Division; Cell Transformation, Neoplast | 2002 |
[Dynamic study on expression of gelatinase A and its natural inhibitor during invasion and metastasis of induced lung cancer in Wistar rats].
Topics: Alkylating Agents; Animals; Carcinoma, Squamous Cell; Diethylnitrosamine; Female; Gene Expression Re | 2002 |
On the significance of sex hormones in producing experimental prostate tumor in the rat.
Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinoma, Squamous Cell; Male; Methylcholanthrene; Neoplasm Meta | 1977 |
Electron microscopic observations on formation of pulmonary metastases.
Topics: Animals; Cell Nucleolus; Cell Nucleus; Cytoplasm; Endoplasmic Reticulum; Fibrosarcoma; Inclusion Bod | 1975 |
Induction of metastasizing carcinoma in rats and their biological characteristics.
Topics: Adenocarcinoma; Animals; Carcinoma; Carcinoma, Intraductal, Noninfiltrating; Female; Methylcholanthr | 1975 |
A tumor-associated organ-specific antigen characteristic of spontaneously metastatic rat mammary carcinomas.
Topics: Animals; Antigens, Neoplasm; Cross Reactions; Glycoproteins; Mammary Neoplasms, Experimental; Methyl | 1979 |
Immune impairment and metastatic tumor growth: the need for an immunorestorative drug as an adjunct to surgery.
Topics: Animals; Antibodies, Neoplasm; Antibody Specificity; Cytotoxicity, Immunologic; Female; Fibrosarcoma | 1979 |
Tumor metastases and cell-mediated immunity in a model system in DBA/2 mice. 2. Characteristics of a metastasizing variant of a chemically induced lymphoma.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Disease Models, Animal; Graft Rejection; Histoc | 1979 |
Methylcholanthrene-induced metastatic mammary carcinoma in several inbred hamster strains.
Topics: Animals; Cricetinae; Cystadenoma; Female; Lung Neoplasms; Lymphatic Metastasis; Male; Mammary Neopla | 1979 |
Enhancement of carcinogenesis by prostaglandins.
Topics: Animals; Carcinoma, Squamous Cell; Cocarcinogenesis; DNA, Neoplasm; Methylcholanthrene; Mice; Neopla | 1978 |
The effect of gold salts on tumour immunity and its stimulation by Corynebacterium Parvum.
Topics: Animals; Antibodies; Ascitic Fluid; Erythrocytes; Fibrosarcoma; Gold Sodium Thiomalate; Hemagglutina | 1975 |
[Mycoplasma as infectious causal or therapeutic factors in malignant tumors (author's transl)].
Topics: Animals; BCG Vaccine; Leukemia; Melanoma; Methylcholanthrene; Mycoplasma; Mycoplasma Infections; Neo | 1975 |
Concomitant elevations in serum sialytransferase activity and sialic acid content in rats with metastasizing mammary tumors.
Topics: Animals; Female; Liver; Mammary Neoplasms, Experimental; Methylcholanthrene; Microsomes; Neoplasm Me | 1977 |
Transplantability and metastasibility of an MCA-induced sarcoma in nude mice. Influence of transfer of thymus cells and adoptive immunity.
Topics: Animals; Injections, Intravenous; Injections, Subcutaneous; Methylcholanthrene; Mice; Mice, Inbred C | 1977 |
Bacillus Calmette-Guérin contact immunotherapy of local and metastatic deposits of rat tumors.
Topics: Animals; BCG Vaccine; Female; Immunosuppression Therapy; Immunotherapy; Lung Neoplasms; Male; Methyl | 1976 |
Identification of premalignant hyperplasia in methylcholanthrene-induced mammary tumorogenesis.
Topics: Aneuploidy; Animals; Chromosome Aberrations; Estradiol; Female; Hyperplasia; Mammary Glands, Animal; | 1975 |
Studies on the role of macrophages in regulation of growth and metastasis of murine chemically induced fibrosarcomas.
Topics: Animals; Binding Sites; Cell Membrane; Fibrosarcoma; Immune Adherence Reaction; Macrophages; Male; M | 1975 |
Tumour metastasis in mice with reduced immune reactivity. IV. Restoration of relative resistance to metastasis formation in thymectomized sub-lethally irradiated mice by spleen cells.
Topics: Animals; Carcinogens; Carcinoma, Squamous Cell; Female; Immunity; Immunosuppression Therapy; Male; M | 1975 |
Levamisole treatment of local and metastatic growth of transplanted rat tumours.
Topics: Animals; Antigens, Neoplasm; Levamisole; Lung Neoplasms; Methylcholanthrene; Neoplasm Metastasis; Ne | 1975 |
Pituitary role in the growth of metastasizing MRMT-1 mammary carcinoma in rats.
Topics: Animals; Female; Hypophysectomy; Lung Neoplasms; Mammary Neoplasms, Experimental; Methylcholanthrene | 1976 |
Metastasis formation after intravenous tumour cell injection in thrombocytopenic rats.
Topics: Animals; Dextrans; Femoral Fractures; Fibrosarcoma; Lung Neoplasms; Methylcholanthrene; Neoplasm Met | 1976 |
Analysis of a bioassay for circulating tumor cells in two murine malignancies: Correlations with tumor age and extent of metastatic disease.
Topics: Animals; Biological Assay; Female; Fibrosarcoma; Melanoma; Methylcholanthrene; Mice; Mice, Inbred C5 | 1976 |
Effect of Corynebacterium parvum on the response to irradiation of a C3H fibrosarcoma.
Topics: Adjuvants, Immunologic; Animals; Dose-Response Relationship, Radiation; Female; Fibrosarcoma; Graft | 1976 |
Protection by methylcholanthrene against hepatic carcinogenesis in rats ingesting N-4-(4'-fluorobiphenyl) acetamide.
Topics: Aminobiphenyl Compounds; Animals; Carcinogens; Carcinoma; Kidney Neoplasms; Liver Neoplasms; Lung Ne | 1976 |
Fibrosarcoma cells transduced with the IL-6 gene exhibited reduced tumorigenicity, increased immunogenicity, and decreased metastatic potential.
Topics: Animals; Female; Fibrosarcoma; Graft Rejection; Histocompatibility Antigens Class I; Immunocompromis | 1992 |
Somatic mutation during metastasis of a mouse fibrosarcoma line detected by DNA fingerprint analysis.
Topics: Animals; Base Sequence; DNA Fingerprinting; DNA Mutational Analysis; DNA, Neoplasm; DNA, Satellite; | 1992 |
Differences in cellular proteins between high and low metastatic potential sublines from the methylcholanthrene-induced rat fibrosarcoma cell line.
Topics: Animals; Electrophoresis, Gel, Two-Dimensional; Fibrosarcoma; Glycoproteins; In Vitro Techniques; Is | 1992 |
Heterogeneity of MHC-class-I antigens in clones of methylcholanthrene-induced tumors. Implications for local growth and metastasis.
Topics: Animals; Cell Division; Cell Line; Clone Cells; Cytotoxicity, Immunologic; DNA, Neoplasm; Fibrosarco | 1991 |
Coagulant and fibrinolytic activities of a metastasising and non-metastasising tumour line.
Topics: Animals; Blood Coagulation; Fibrinolysis; Fibrosarcoma; Male; Methylcholanthrene; Neoplasm Metastasi | 1990 |
Enhanced lung colonization and tumorigenicity of fused cells isolated from primary MCA tumors.
Topics: Animals; Cell Fusion; Clone Cells; Glucose-6-Phosphate Isomerase; Lung Neoplasms; Methylcholanthrene | 1990 |
Selection and isolation of a new variant of DBA/2 mastocytoma P 815 X 2.
Topics: Animals; Ascites; Liver Neoplasms, Experimental; Mast-Cell Sarcoma; Methylcholanthrene; Mice; Mice, | 1989 |
[Blood coagulation and metastasis].
Topics: Animals; Fibrosarcoma; Humans; Lung Neoplasms; Membrane Proteins; Methylcholanthrene; Mice; Neoplasm | 1989 |
[Effects of hyperbaric oxygenation on tumor growth].
Topics: Animals; Female; Hyperbaric Oxygenation; Melanoma, Experimental; Methylcholanthrene; Mice; Mice, Inb | 1989 |
Neoplastic transformation of SV40-immortalized human urinary tract epithelial cells by in vitro exposure to 3-methylcholanthrene.
Topics: Animals; Cell Transformation, Neoplastic; Chromosome Aberrations; Female; Humans; Methylcholanthrene | 1988 |
Pathogenesis and characteristics of spontaneously metastasizing mammary carcinomas and the general principle of metastasis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Antigens, Neoplasm; Antigens, Surface; Fe | 1986 |
In adequate tumor surgery of chemically induced soft tissue sarcomas--an experimental approach for induction of metastasis formation?
Topics: Animals; Female; Male; Methylcholanthrene; Mice; Mice, Inbred Strains; Mice, Nude; Neoplasm Metastas | 1988 |
Association in the expression of Kirsten-ras oncogene and the major histocompatibility complex class I antigens in fibrosarcoma tumor cell variants exhibiting different metastatic capabilities.
Topics: Animals; Clone Cells; Fibrosarcoma; Gene Expression Regulation; H-2 Antigens; Histocompatibility Ant | 1987 |
Establishment and characterization of high- and low-metastatic clones derived from a methylcholanthrene-induced rat fibrosarcoma.
Topics: Animals; Cell Line; Fibrosarcoma; Growth Substances; Karyotyping; Lung Neoplasms; Macrophages; Methy | 1986 |
Altered experimental metastasis pattern by proteolytic cell treatment.
Topics: Animals; Ascites; Blood Coagulation; Carcinoma, Squamous Cell; Cell Separation; Concanavalin A; Elec | 1985 |
Therapeutic effects of PS-K and busulfan on the recurrent and metastatic diseases after the surgical removal of 3-methylcholanthrene-induced autochthonous tumors in C57BL/6 mice.
Topics: Adjuvants, Immunologic; Animals; Busulfan; Female; Methylcholanthrene; Mice; Mice, Inbred C57BL; Neo | 1985 |
Characterization of spontaneous metastases from autochthonous 3-methylcholanthrene-induced tumors.
Topics: Animals; Cell Line; Kidney Neoplasms; Lung Neoplasms; Methylcholanthrene; Mice; Mice, Inbred C3H; Mi | 1986 |
[Comparative analysis of the malignancy of tumors in mice induced by 20-methylcholanthrene].
Topics: Animals; Cell Line; Cells, Cultured; Methylcholanthrene; Mice; Mice, Inbred BALB C; Mice, Inbred C3H | 1985 |
Spontaneous tumor regression. Experimental aspects.
Topics: Animals; Antibodies; Antibody Formation; Antigens, Neoplasm; B-Lymphocytes; Bone Neoplasms; Epitopes | 1974 |
Experimental metastasizing in syngeneic and autochthonous tumour-host systems.
Topics: Animals; Benzopyrenes; Cell Transformation, Neoplastic; Disease Models, Animal; Graft vs Host Reacti | 1972 |
Induced hyperlipemia and the dissemination of tumor cells.
Topics: Animals; Carcinoma, Hepatocellular; Emulsions; Hyperlipidemias; Injections, Intravenous; Liver Neopl | 1967 |
Biological behavior through successive transplant generations of transplantable tumors derived originally from primary chemically induced and spontaneous sources in mice.
Topics: Animals; Ethiodized Oil; Iodized Oil; Lung Neoplasms; Methylcholanthrene; Mice; Neoplasm Metastasis; | 1968 |
[Experimental hematogenous metastasis of a fibrosarcoma in animals with and without spleen].
Topics: Animals; Antibody Formation; Carcinoma, Hepatocellular; Fibrosarcoma; Liver Neoplasms; Lung Neoplasm | 1969 |
Experimental studies on trauma and metastasis formation.
Topics: Animals; Blood Coagulation; Carcinoma, Hepatocellular; Dextrans; Female; Fibrinolysis; Heparin; Inje | 1968 |
Virus particles in rat mammary tumors of varying origin.
Topics: Animals; Benz(a)Anthracenes; Cholesterol; Diethylstilbestrol; Estradiol; Female; Leukemia Virus, Mur | 1970 |
Rapid development of bronchiolo-alveolar squamous cell tumors in rats after intratracheal injection of 3-methylcholanthrene.
Topics: Adenocarcinoma, Bronchiolo-Alveolar; Animals; Carcinoma, Squamous Cell; Methylcholanthrene; Neoplasm | 1972 |
A preliminary investigation into the role of immunity in modifying the blood- borne spread of chemically induced rat sarcomas.
Topics: Animals; Benzopyrenes; Carcinogens; Carcinoma, Hepatocellular; Ethionine; Graft Rejection; Immunizat | 1974 |
Cytolipin R and its possible precursor ceramide trisaccharide from metastatic rat mammary tumor.
Topics: Animals; Antigens, Neoplasm; Ceramides; Cerebrosides; Chromatography, Thin Layer; Fatty Acids; Femal | 1974 |
Tumor metastasis in mice with reduced immune reactivity. II. Studies with a highly antigenic MCA-induced sarcoma in thymectomized and/or sub-lethally irradiated C57BL/6J mice.
Topics: Animals; Antibody Formation; Antigens, Neoplasm; Female; Gammaretrovirus; Hemagglutination Tests; Im | 1974 |
[Mechanisms of experimental hematogenous metastasis and its dependence on the reactive defense in the host organism].
Topics: Animals; Benzopyrenes; Carcinogens; Immunity; Male; Methylcholanthrene; Mice; Mice, Inbred Strains; | 1974 |
Immunoprophylaxis and immunotherapy for a murine fibrosarcoma with C. granulosum and C. parvum.
Topics: Animals; Cell Transformation, Neoplastic; Corynebacterium; Female; Fibrosarcoma; Immunization; Liver | 1974 |
BCG immunotherapy of rat tumors of defined immunogenicity.
Topics: Adjuvants, Immunologic; Animals; Antigens, Neoplasm; BCG Vaccine; Cell Count; Immunity; Immunosuppre | 1973 |
The influence of host immunity on the arrest of circulating cancer cells, and its modification by neuraminidase.
Topics: Animals; Antigens, Neoplasm; Cell Migration Inhibition; Estradiol; Female; Fibrosarcoma; Fluorescent | 1974 |
A factor preventing the development of lung metastases in rats with sarcomas.
Topics: Animals; Antibody Formation; Immune Sera; Immunity, Maternally-Acquired; Immunization, Passive; Leg; | 1973 |
Effect of excision or local radiotherapy to a tumor and its regional nodes on metastases.
Topics: Amputation, Surgical; Animals; Female; Fibrosarcoma; Lung Neoplasms; Mammary Neoplasms, Experimental | 1973 |
The metastatic potential of experimental pulmonary metastases.
Topics: Animals; Female; Immune Sera; Lung Neoplasms; Methods; Methylcholanthrene; Mice; Mice, Inbred C57BL; | 1973 |
Methylcholanthrene carcinogenesis in the North American opossum (Didelphis virginiana).
Topics: Animals; Biopsy; Disease Models, Animal; Female; Lymphatic Metastasis; Melanoma; Methylcholanthrene; | 1973 |
Capillary blood flow, exchange and flow distribution in transplantable rat tumors.
Topics: Animals; Antipyrine; Capillaries; Capillary Permeability; Iodine Radioisotopes; Methylcholanthrene; | 1973 |
The effect of splenectomy on fibrosarcoma "metastases" in lungs of mice.
Topics: Animals; Fibrosarcoma; Immunity, Active; Lung Neoplasms; Lymphocytes; Male; Methylcholanthrene; Mice | 1973 |
Immunological resistance to pulmonary metastases in C3Hf-Bu mice bearing syngeneic fibrosarcoma of different sizes.
Topics: Animals; Antigen-Antibody Complex; Fibrosarcoma; Immunity, Cellular; Immunization; Immunization, Pas | 1974 |
Frequency and organ distribution of lung tumor metastases in CF-1 mice.
Topics: Animals; Carcinoma; Female; Heart Neoplasms; Kidney; Kidney Neoplasms; Liver; Liver Neoplasms; Lung | 1974 |
In vitro demonstration of altered antigenicity of metastases from a primary methylcholanthrene-induced sarcoma.
Topics: Animals; Antigens, Neoplasm; Fibrosarcoma; In Vitro Techniques; Lung Neoplasms; Lymphocytes; Methylc | 1974 |
Further observations concerning effects of antilymphocyte serum on tumor growth: with special reference to allogeneic inhibition.
Topics: Animals; Antigen-Antibody Reactions; Antigens; Antilymphocyte Serum; Culture Techniques; Female; Flu | 1970 |
Effect of barbital on carcinogenic action and metabolism of 4-dimethylaminoazobenzene.
Topics: Aminobenzoates; Animals; Barbiturates; Bile; Glucuronates; Liver; Liver Neoplasms; Lung Neoplasms; M | 1967 |
Experimental cancer of the lung in rabbits induced by chemical carcinogens.
Topics: Adenocarcinoma; Animals; Autopsy; Bronchoscopy; Carcinogens; Carcinoma; Carcinoma, Squamous Cell; Cy | 1972 |
Altered antigenicity in spontaneous pulmonary metastases from an antigenic murine sarcoma.
Topics: Animals; Antigens; Antigens, Neoplasm; Body Weight; Lung Neoplasms; Methylcholanthrene; Mice; Neopla | 1972 |
Immunotherapy combined with primary resection of murine fibrosarcoma: correlation of immunological status of the host with prevention of metastases.
Topics: Amputation, Surgical; Animals; Antibodies, Neoplasm; Antigen-Antibody Complex; Antigen-Antibody Reac | 1972 |
Studies on the effect of methoxy-substituted glycerol ethers on tumour growth and metastasis formation.
Topics: Administration, Oral; Animals; Body Weight; Ethers; Female; Glycerol; Injections, Intraperitoneal; I | 1971 |
The fate of circulating methylcholanthrene tumor cells in mice with tumor-specific immunity.
Topics: Amputation, Surgical; Animals; Culture Techniques; Disease Models, Animal; Female; Hindlimb; Immunit | 1971 |
Methylcholanthrene-induced endometrial carcinoma in mice and rats: a histological and ultrastructural study.
Topics: Adenocarcinoma; Animals; Carcinoma, Squamous Cell; Carcinosarcoma; Cell Nucleus; Cytoplasm; Endometr | 1971 |
Progression of pulmonary tumor in mice. 1. Histological studies of primary and transplanted pulmonary tumors.
Topics: Adenocarcinoma; Age Factors; Animals; Carcinoma; Injections, Intraperitoneal; Injections, Subcutaneo | 1971 |
Induction of squamous cell carcinoma in the respiratory tract of mice.
Topics: Animals; Carcinoma, Squamous Cell; Injections; Lung; Male; Methylcholanthrene; Mice; Mice, Inbred St | 1971 |
The effect of bilateral adrenalectomy and ovariectomy on the induction of carcinoma of the mouse uterine cervix.
Topics: Adrenal Glands; Adrenalectomy; Animals; Carcinoma, Squamous Cell; Castration; Cell Transformation, N | 1969 |
Experimental tumour metastases and blood coagulability.
Topics: Aminocaproates; Animals; Blood Coagulation; Coumarins; Female; Heparin; Lung Neoplasms; Male; Melano | 1970 |
Histochemical and submicroscopic studies on sialic acid in induced epidermal cancer in relation to cell detachment and metastasis.
Topics: Animals; Carcinoma, Squamous Cell; Histocytochemistry; Hyperplasia; Methylcholanthrene; Mice; Micros | 1969 |
[Experimental carcinogenesis in mollusca. 2. Transplantation experiments with a chemically-induced adenopapilloma in a La-Plata apple snail, Ampullarius australis d'Orbigny (Gastropoda,Prosobranchia)].
Topics: Adenocarcinoma; Adenoma; Animals; Croton Oil; Cystadenoma; Methylcholanthrene; Neoplasm Metastasis; | 1969 |
Effect of heparin, coumarin and -aminocaproic acid (EACA) on spontaneous metastasis formation. Influence on the moment of metastasis formation. Possible cytotoxic effect of heparin and coumarin in blood.
Topics: Aminocaproates; Animals; Coumarins; Heparin; Lung Neoplasms; Lymphatic Metastasis; Methylcholanthren | 1969 |
Metastasizing mammary carcinomas in rats: induction and study of their immunogenicity.
Topics: Adenocarcinoma; Animals; Antigens; Female; Mammary Neoplasms, Experimental; Methylcholanthrene; Neop | 1970 |
Evidence for effects of heparin on cell surfaces influencing experimental metastases.
Topics: Animals; Chondroitin; Heparin; In Vitro Techniques; Methylcholanthrene; Neoplasm Metastasis; Protami | 1970 |
The nature and mechanism of metastasis.
Topics: Animals; Contact Inhibition; Cricetinae; Humans; Lymphatic Metastasis; Methylcholanthrene; Mice; Neo | 1970 |
[The effect of iron-dextran and ironfree colloid on the distribution of experimental metastases].
Topics: Animals; Antineoplastic Agents; Iron-Dextran Complex; Liver Neoplasms; Lung Neoplasms; Methylcholant | 1970 |
[Distribution and development of experimental metastasis after treatment with anticoagulants].
Topics: Animals; Anticoagulants; Heparin; Injections, Intravenous; Melanoma; Methylcholanthrene; Mice; Neopl | 1970 |
[Spontaneous metastasising of a methylcholanthrene induced sarcoma in animals with intact respective reduced immune reactivity].
Topics: Animals; Methylcholanthrene; Mice; Neoplasm Metastasis; Neoplasm Transplantation; Radiation Effects; | 1970 |
Effect of pyran copolymer on phagocytosis and tumor growth.
Topics: Animals; Antineoplastic Agents; Female; Injections, Intramuscular; Male; Methylcholanthrene; Mice; M | 1971 |
Antigenic specificities on murine sarcoma cells. Reciprocal relationship between normal transplantation antigens (H-2) and tumor-specific immunogenicity.
Topics: Animals; Antigen-Antibody Reactions; Chromium Isotopes; Cytotoxicity Tests, Immunologic; Female; His | 1971 |
Effect of immune status on the development of artificially induced metastases in different anatomical locations.
Topics: Animals; Immune Tolerance; Injections, Intraperitoneal; Injections, Subcutaneous; Liver Neoplasms; L | 1971 |
The causes of lung cancer.
Topics: Aerosols; Air Pollution; Animals; Carcinogens; Carcinoma, Squamous Cell; Cricetinae; In Vitro Techni | 1968 |
[Experimental carcinogenesis in mollusca. 1. Chemically induced epithelial tumors in the La-Plata apple snail Ampullarius australis d'Orbigny (Gastropoda, Prosobranchia)].
Topics: Adenocarcinoma; Animals; Croton Oil; Methylcholanthrene; Neoplasm Metastasis; Neoplasms, Experimenta | 1968 |
Warfarin treatment of mice bearing autochthonous tumors: effect on spontaneous metastases.
Topics: Animals; Female; Lung Neoplasms; Methylcholanthrene; Mice; Neoplasm Metastasis; Neoplasm Transplanta | 1968 |
Effect of heparin, epsilon-aminocaproic acid and protamine on spontaneous metastasis formation from resectable tail-tumours.
Topics: Aminocaproates; Animals; Anticoagulants; Antifibrinolytic Agents; Heparin; Lung Neoplasms; Methylcho | 1968 |
Effect of heparin, epsilon-aminocaproic acid and coumarin on tumour growth and spontaneous metastasis formation.
Topics: Aminocaproates; Animals; Anticoagulants; Antifibrinolytic Agents; Coumarins; Heparin; Lung Neoplasms | 1968 |
Experimental lung cancer in rabbits induced by chemical carcinogens.
Topics: Adenocarcinoma; Animals; Bronchi; Carcinogens; Carcinoma, Squamous Cell; Diaphragm; Female; Injectio | 1968 |
[Pulmonary metastasization and allotransplantability (murine sarcoma caused by methylcholanthrene)].
Topics: Animals; Lung Neoplasms; Methylcholanthrene; Mice; Neoplasm Metastasis; Neoplasm Transplantation; Sa | 1968 |
Effect of antilymphocyte serum on parameters of growth of MCA-induced tumours.
Topics: Animals; Antilymphocyte Serum; Carcinoma; Immune Sera; Lymphocytes; Methylcholanthrene; Neoplasm Met | 1969 |
The development of carcinoma in liver of rats treated with m-toluylenediamine and the synergistic and antagonistic effects with other chemicals.
Topics: Aniline Compounds; Animals; Diet; Drug Antagonism; Drug Synergism; Ethionine; Liver Neoplasms; Male; | 1969 |
Metastasis of experimentally induced skin tumors.
Topics: Animals; Carcinoma, Squamous Cell; Lung Neoplasms; Lymphatic Metastasis; Methylcholanthrene; Mice; N | 1965 |
Factors controlling metastasis of experimental breast cancer.
Topics: Adenocarcinoma; Animals; Mammary Neoplasms, Experimental; Methylcholanthrene; Neoplasm Metastasis; R | 1966 |
A spontaneously metastasizing 20-methylcholanthrene-induced rhabdomyosarcoma and its transformation to ascites form in the CBA mouse.
Topics: Animals; Carcinogens; Chromosome Aberrations; Chromosome Disorders; Female; Injections, Intraperiton | 1966 |
Effect of heparin and plasminogen inhibitor (EACA) in brief and prolonged treatment on intravenously injected tumour cells.
Topics: Aminocaproates; Animals; Heparin; Liver Neoplasms; Lung Neoplasms; Methylcholanthrene; Mice; Neoplas | 1966 |