3-methylcholanthrene has been researched along with Metaplasia in 30 studies
Methylcholanthrene: A carcinogen that is often used in experimental cancer studies.
3-methylcholanthrene : A pentacyclic ortho- and peri-fused polycyclic arene consisting of a dihydrocyclopenta[ij]tetraphene ring system with a methyl substituent at the 3-position.
Metaplasia: A condition in which there is a change of one adult cell type to another similar adult cell type.
| Excerpt | Relevance | Reference |
|---|---|---|
| "It was suggested that the epithelial hyperplasia and metaplasia of respiratory tract induced by MCA can be suppressed by the administration of folic acid." | 3.68 | Experimental study of the therapeutic effects of folate, vitamin A, and vitamin B12 on squamous metaplasia of the bronchial epithelium. ( Fukuma, S; Hayashi, Y; Kamei, T; Kohno, T; Ohwada, H; Takeuchi, Y, 1993) |
| "Severe dysplasia or questionable squamous cell carcinoma in situ was noted at the site of the bronchial gland in a segment removed 8 weeks after transplantation, and invasive squamous cell carcinoma in a segment removed 15 weeks after transplantation." | 1.26 | Induction of squamous cell carcinoma in human bronchi transplanted into nude mice. ( Kameya, T; Kodama, T; Shimosato, Y; Tamai, S, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 27 (90.00) | 18.7374 |
| 1990's | 3 (10.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| CAPURRO, P | 1 |
| ANGRIST, A | 1 |
| BLACK, J | 1 |
| MOUMGIS, B | 1 |
| BONSER, GM | 1 |
| BOYLAND, E | 1 |
| BUSBY, ER | 1 |
| CLAYSON, DB | 1 |
| GROVER, PL | 1 |
| JULL, JW | 1 |
| BEOHAR, PC | 1 |
| GOLDHABER, P | 1 |
| HERTIG, AT | 1 |
| MILCU, SM | 1 |
| PETREA, I | 1 |
| Feit, J | 3 |
| Svejda, J | 2 |
| Hoffmann, M | 2 |
| Sochorová, M | 1 |
| Schaefer, FV | 1 |
| Custer, RP | 1 |
| Sorof, S | 1 |
| Konaka, C | 3 |
| Auer, G | 3 |
| Nasiell, M | 3 |
| Kato, H | 3 |
| Hayashi, N | 1 |
| Ono, J | 2 |
| Hayata, Y | 3 |
| Caspersson, TO | 1 |
| Carlens, E | 1 |
| Roger, V | 1 |
| Nasiell, K | 1 |
| Enstad, I | 1 |
| Iimura, I | 1 |
| Matsushima, Y | 1 |
| Tahara, M | 1 |
| Lei, J | 1 |
| Wieman, TJ | 1 |
| Max, MH | 1 |
| Voyles, CR | 1 |
| Barrows, GH | 1 |
| Shimosato, Y | 1 |
| Kodama, T | 1 |
| Tamai, S | 1 |
| Kameya, T | 1 |
| Hammond, WG | 2 |
| Teplitz, RL | 2 |
| Benfield, JR | 2 |
| Kamei, T | 1 |
| Kohno, T | 1 |
| Ohwada, H | 1 |
| Takeuchi, Y | 1 |
| Hayashi, Y | 1 |
| Fukuma, S | 1 |
| Lasnitzki, I | 2 |
| Indo, K | 1 |
| Wilson, RB | 1 |
| Jia, XS | 1 |
| Ren, J | 1 |
| Cone, MV | 1 |
| Nettesheim, P | 1 |
| Goodman, DS | 1 |
| Medina, D | 1 |
| Graham, CE | 2 |
| Ackerman, NB | 1 |
| Smith, WE | 1 |
| Yazdi, E | 1 |
| Miller, L | 1 |
| Tokuoka, S | 1 |
| Ghidoni, JJ | 1 |
| Campbell, MM | 1 |
| Kaminetzky, HA | 1 |
30 other studies available for 3-methylcholanthrene and Metaplasia
| Article | Year |
|---|---|
Studies in squamous metaplasia in rat bladder. I. Effects of hypovitaminosis A, foreign bodies, and methylcholanthrene.
Topics: Foreign Bodies; Metaplasia; Methylcholanthrene; Urinary Bladder; Vitamin A Deficiency | 1960 |
A further study of bladder implantation in the mouse as a means of detecting carcinogenic activity: use of crushed paraffin wax or stearic acid as the vehicle.
Topics: Animals; Azo Compounds; Carcinogens; Carcinoma; Humans; Hydroxylamines; Metaplasia; Methylcholanthre | 1963 |
EFFECT OF 3-METHYLCHOLANTHRENE CRYSTALS AND SOLUTIONS ON THE CHORIO-ALLANTOIC MEMBRANE OF THE DEVELOPING CHICK EMBRYO.
Topics: Acetone; Allantois; Animals; Carcinogens; Chick Embryo; Embryonic Development; Extraembryonic Membra | 1964 |
[On the capacity of the thyroid gland tissue for metaplasia under the influence of methylcholanthrene and endogenous thyrotropic hormone].
Topics: Metaplasia; Methylcholanthrene; Thyroid Gland; Thyrotropin | 1960 |
Experimentally produced precancerosis of the lung in rats.
Topics: Animals; Carcinoma, Squamous Cell; Lung Neoplasms; Metaplasia; Methylcholanthrene; Rats | 1967 |
Experimental intestinal metaplasia of gastric mucosa of rats and its relationship to carcinoma.
Topics: Adenocarcinoma; Animals; Metaplasia; Methylcholanthrene; Neoplasms, Radiation-Induced; Phosphorus Is | 1967 |
General process of induction of squamous metaplasia by cyclic adenine nucleotide and prostaglandins: mouse prostate glands.
Topics: Animals; Bucladesine; Culture Techniques; Drug Synergism; Epithelium; Keratins; Male; Metaplasia; Me | 1982 |
Pathogenesis of squamous bronchial carcinoma in 20-methylcholanthrene-treated beagle dogs.
Topics: Animals; Bronchial Neoplasms; Carcinoma, Squamous Cell; Cell Nucleus; Cytoplasm; DNA, Neoplasm; Dogs | 1982 |
Pathogenesis of bronchial carcinoma, with special reference to morphogenesis and the influence on the bronchial mucosa of 20-methylcholanthrene and cigarette smoking.
Topics: Bronchi; Bronchial Neoplasms; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; DNA; Epithelium; Hi | 1982 |
Lung cancer histogenesis following in vivo bronchial injections of 20-methylcholanthrene in dogs.
Topics: Animals; Biopsy; Bronchi; Bronchoscopy; Carcinoma in Situ; Carcinoma, Squamous Cell; DNA; Dogs; Fibe | 1982 |
Diversion of duodenal contents: its effect on the production of experimental gastric cancer.
Topics: Adenocarcinoma; Animals; Duodenum; Gastric Mucosa; Gastroenterostomy; Male; Metaplasia; Methylcholan | 1980 |
Induction of squamous cell carcinoma in human bronchi transplanted into nude mice.
Topics: Adult; Animals; Bronchi; Bronchial Neoplasms; Carcinoma, Squamous Cell; Female; Humans; Hyperplasia; | 1980 |
A step section method for full histopathological assessment of carcinogen-affected target tissue during respiratory carcinogenesis.
Topics: Animals; Benzo(a)pyrene; Carcinoma in Situ; Cricetinae; Female; Lung Neoplasms; Male; Metaplasia; Me | 1993 |
Experimental study of the therapeutic effects of folate, vitamin A, and vitamin B12 on squamous metaplasia of the bronchial epithelium.
Topics: Animals; Body Weight; Bronchi; Epithelium; Folic Acid; Hyperplasia; Metaplasia; Methylcholanthrene; | 1993 |
Reversal of methylcholanthrene-induced changes in mouse prostates in vitro by retinoic acid and its analogues.
Topics: Animals; DNA; Hyperplasia; In Vitro Techniques; Male; Metaplasia; Methylcholanthrene; Mice; Mice, In | 1976 |
Cell interactions between epithelial and mesenchymal components in primary sheets of fetal rat lung cells, and the effects of 3-methylcholanthrene treatment.
Topics: Animals; Cell Aggregation; Cell Differentiation; Cell Division; Culture Techniques; Epithelial Cells | 1976 |
Variable regression of experimental bronchial preneoplasia during carcinogenesis.
Topics: Animals; Bronchi; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Disease Models, Animal; Dogs; L | 1991 |
[Ultrastructural and histogenetic studies on experimental pulmonary carcinoma].
Topics: Adenocarcinoma; Adenocarcinoma, Bronchiolo-Alveolar; Animals; Benzo(a)pyrene; Carcinoma, Squamous Ce | 1987 |
[Ultrastructural study on the tracheal epithelium of hamsters induced by chemical carcinogen].
Topics: Animals; Benzo(a)pyrene; Cell Transformation, Neoplastic; Cricetinae; Culture Techniques; Epithelium | 1987 |
Effects of vitamin A on 3-methylcholanthrene-induced squamous metaplasias and early tumors in the respiratory tract of rats.
Topics: Animals; Carcinoma, Squamous Cell; Hyperplasia; Injections; Intubation, Gastrointestinal; Liver; Lun | 1973 |
Inhibition of the effects of methylcholanthrene on mouse prostate in organ culture by vitamin A and its analogs.
Topics: Animals; Cell Differentiation; Cell Division; Epithelial Cells; Epithelium; Hyperplasia; Male; Metap | 1974 |
Mammary tumorigenesis in chemical carcinogen-treated mice. I. Incidence in BALB-c and C57BL mice.
Topics: Adenocarcinoma; Animals; Benz(a)Anthracenes; Carcinogens; Hyperplasia; Mammary Neoplasms, Experiment | 1974 |
Thread-induced epidermization in the uterine horn of mice, and the influence of 20-methylcholanthrene.
Topics: Animals; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cervix Uteri; Epithelium; Evalua | 1971 |
Bone formation in the gastric mucosa following subtotal gastrectomy in rats.
Topics: Animals; Benzopyrenes; Gastrectomy; Gastric Mucosa; Hydrochloric Acid; Metaplasia; Methylcholanthren | 1968 |
Carcinogenesis in pulmonary epithelia in mice on different levels of vitamin A.
Topics: Adenocarcinoma; Animals; Body Weight; Carcinoma, Squamous Cell; Lung Neoplasms; Male; Metaplasia; Me | 1972 |
Methylcholanthrene-induced endometrial carcinoma in mice and rats: a histological and ultrastructural study.
Topics: Adenocarcinoma; Animals; Carcinoma, Squamous Cell; Carcinosarcoma; Cell Nucleus; Cytoplasm; Endometr | 1971 |
Histogenesis of methylcholanthrene-induced murine cervical cancer.
Topics: Animals; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cervix Uteri; Epithelium; Female | 1971 |
[Experimental bronchial precancerosis and carcinoma of the rat lung].
Topics: Animals; Bronchial Neoplasms; Carcinoma; Lung Neoplasms; Metaplasia; Methylcholanthrene; Neoplasms, | 1967 |
Fine structure of metaplastic cornified squamous epithelium in the urinary bladder of rats.
Topics: Animals; Cytoplasmic Granules; Epithelium; Estradiol; Keratins; Metaplasia; Methylcholanthrene; Micr | 1969 |
Experimental cervical dysplasa in the rhesus monkey. II.
Topics: Animals; Carcinoma; Cervix Uteri; Estradiol; Female; Injections, Intramuscular; Macaca; Metaplasia; | 1971 |