3-methylcholanthrene has been researched along with Lung Neoplasms in 295 studies
Methylcholanthrene: A carcinogen that is often used in experimental cancer studies.
3-methylcholanthrene : A pentacyclic ortho- and peri-fused polycyclic arene consisting of a dihydrocyclopenta[ij]tetraphene ring system with a methyl substituent at the 3-position.
Lung Neoplasms: Tumors or cancer of the LUNG.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of tuftsin therapy on tumor development was examined in a murine primary fibrosarcoma and the Lewis lung carcinoma systems." | 7.67 | Effect of tuftsin on in vivo development of 3-methylcholanthrene-induced primary fibrosarcoma and Lewis lung carcinoma in mice. ( Babcock, GF; Banks, RA; Kazazi, F; Nishioka, K, 1985) |
| "Tumor-specific transplantation antigens (TSTA), which were partially purified by preparative isoelectric focusing of 3-M KCl extracts of a fibrosarcoma MCA-F induced in inbred female C3H/HeJ mice with 3-methylcholanthrene and previously shown to display immunotherapeutic activity against subcutaneous neoplasms, were effective against pulmonary metastases." | 7.66 | Immunotherapeutic effects of partially purified tumor-specific transplantation antigens on pulmonary metastases of a 3-methylcholanthrene-induced sarcoma in mice: a preliminary report. ( Kahan, BD; Pellis, NR; Tanaka, T, 1982) |
| "The cytotoxic effects in vivo of hydroxyurea (HU) on murine fibrosarcoma (FSa) cells grown as pulmonary tumours were determined." | 7.66 | Phase-specific cytotoxicity in vivo of hydroxyurea on murine fibrosarcoma pulmonary nodules. ( Grdina, DJ, 1982) |
| "Long-term oral administration of sodium warfarin significantly reduced the incidence of spontaneous metastases in the lungs from 83 percent in controls to 8 percent in treated C57/BL/6N mice." | 7.64 | Warfarin treatment of mice bearing autochthonous tumors: effect on spontaneous metastases. ( Ketcham, AS; Ryan, JJ; Wexler, H, 1968) |
| "Three spontaneous pulmonary adenomas of C mice, morphologically resembling those induced by methylcholanthrene or urethane, were propagated in host after host under conditions such that the neoplastic cells were directly exposed, while proliferating, to one or the other of these agents." | 7.63 | Are carcinogens responsible for the superimposed neoplastic changes occurring in mouse tumor cells? The effect of methylcholanthrene and urethane on pulmonary adenomas and of methylcholanthrene on mammary carcinomas. ( DUMBELL, K; ROUS, P, 1955) |
| "The emodin treatment induced P450s 1A1 and 1B1 mRNA in human lung carcinoma NCI-H322 and breast cancer MCF-7 cells." | 5.31 | Induction of cytochromes P450 1A1 and 1B1 by emodin in human lung adenocarcinoma cell line CL5. ( Chen, TL; Ueng, TH; Wang, HW; Yang, PC, 2001) |
| "Cell lines from metastases and primary tumors were heterogeneous in tumorigenicity, growth rate, metastatic potential (spontaneous), and colonizing capacity (i." | 5.27 | Characterization of spontaneous metastases from autochthonous 3-methylcholanthrene-induced tumors. ( Bottazzi, B; Giavazzi, R; Mantovani, A; Taraboletti, G, 1986) |
| " In a two-stage lung carcinogenesis model, mice were initiated with 3-methylcholanthrene (10 μg/g; intraperitoneal; 1x) or corn oil then exposed to metal oxides or vehicle (1 x/week for 5 weeks) by oropharyngeal aspiration." | 3.88 | Pulmonary toxicity and lung tumorigenic potential of surrogate metal oxides in gas metal arc welding-stainless steel fume: Iron as a primary mediator versus chromium and nickel. ( Antonini, JM; Battelli, L; Bowers, L; Erdely, A; Falcone, LM; Kashon, ML; Keane, M; Kodali, V; Salmen, R; Stefaniak, AB; Zeidler-Erdely, PC, 2018) |
| " We show herein that resistant C57BL/6J (B6) and intermediately resistant BALB/cByJ (BALB) mice form very few urethane-induced early microadenomas (i." | 3.73 | Quantitative analysis of early chemically-induced pulmonary lesions in mice of varying susceptibilities to lung tumorigenesis. ( Dwyer-Nield, LD; Kisley, LR; Malkinson, AM; O'Donnell, EP; Zerbe, LK, 2006) |
| " Four groups of nontumored, female, C57BL/6 mice and four groups of C57BL/6 mice with pulmonary metastases from a 3-methylcholanthrene-induced fibrosarcoma (MCA-105) were treated every 6 hr for 4 days by intraperitoneal injections of IL-2 alone, IL-2 and IL-8, IL-8 alone, or an equal volume of saline which served as our control." | 3.69 | Interleukin-8 suppresses the toxicity and antitumor effect of interleukin-2. ( Doak, KW; Edwards, MJ; Heniford, BT; Klar, EA; Miller, FN; Wilson, MA, 1994) |
| "A 3-Methylcholanthrene (MC)-induced fibrosarcoma and three of its clones were investigated for their metastatic potential in normal and tumor immune mice." | 3.67 | The effect of immunity on pulmonary metastasis of a methylcholanthrene-induced fibrosarcoma and three of its clones. ( McKhann, CF; Wang, N; Yu, S, 1984) |
| "The effect of tuftsin therapy on tumor development was examined in a murine primary fibrosarcoma and the Lewis lung carcinoma systems." | 3.67 | Effect of tuftsin on in vivo development of 3-methylcholanthrene-induced primary fibrosarcoma and Lewis lung carcinoma in mice. ( Babcock, GF; Banks, RA; Kazazi, F; Nishioka, K, 1985) |
| "Histamine levels increased in the fundus of mice bearing a primary 3-methylcholanthrene-induced fibrosarcoma, and in the ventral skin, skeletal muscle and rumen of rats bearing a D." | 3.66 | Selective increased tissue histamine levels in tumour-bearing rodents. ( Burtin, C; Canu, P; Fray, A; Lespinats, G; Paupe, J; Salomon, JC; Scheinmann, P; Villet, R, 1983) |
| "Tumor-specific transplantation antigens (TSTA), which were partially purified by preparative isoelectric focusing of 3-M KCl extracts of a fibrosarcoma MCA-F induced in inbred female C3H/HeJ mice with 3-methylcholanthrene and previously shown to display immunotherapeutic activity against subcutaneous neoplasms, were effective against pulmonary metastases." | 3.66 | Immunotherapeutic effects of partially purified tumor-specific transplantation antigens on pulmonary metastases of a 3-methylcholanthrene-induced sarcoma in mice: a preliminary report. ( Kahan, BD; Pellis, NR; Tanaka, T, 1982) |
| "The cytotoxic effects in vivo of hydroxyurea (HU) on murine fibrosarcoma (FSa) cells grown as pulmonary tumours were determined." | 3.66 | Phase-specific cytotoxicity in vivo of hydroxyurea on murine fibrosarcoma pulmonary nodules. ( Grdina, DJ, 1982) |
| "Levamisole has been examined for its ability to control local growth and pulmonary metastases of transplanted rat tumours." | 3.65 | Levamisole treatment of local and metastatic growth of transplanted rat tumours. ( Baldwin, RW; Hopper, DG; Pimm, MV, 1975) |
| "Athymic-nude (nu/nu) mice and normal (nu/+) mice showed no differences in either latent period or incidence of local sarcomas or lung adenomas within 120 days after administration of 3-methylcholanthrene at birth." | 3.65 | Tumor development after 3-methylcholanthrene in immunologically deficient athymic-nude mice. ( Stutman, O, 1974) |
| "Long-term oral administration of sodium warfarin significantly reduced the incidence of spontaneous metastases in the lungs from 83 percent in controls to 8 percent in treated C57/BL/6N mice." | 3.64 | Warfarin treatment of mice bearing autochthonous tumors: effect on spontaneous metastases. ( Ketcham, AS; Ryan, JJ; Wexler, H, 1968) |
| "Three spontaneous pulmonary adenomas of C mice, morphologically resembling those induced by methylcholanthrene or urethane, were propagated in host after host under conditions such that the neoplastic cells were directly exposed, while proliferating, to one or the other of these agents." | 3.63 | Are carcinogens responsible for the superimposed neoplastic changes occurring in mouse tumor cells? The effect of methylcholanthrene and urethane on pulmonary adenomas and of methylcholanthrene on mammary carcinomas. ( DUMBELL, K; ROUS, P, 1955) |
| "The occurrence of lung cancer is linked with tobacco smoking, mainly through the generation of polycyclic aromatic hydrocarbons (PAHs)." | 1.51 | Liposome mediated-CYP1A1 gene silencing nanomedicine prepared using lipid film-coated proliposomes as a potential treatment strategy of lung cancer. ( Ahmed, W; Elhissi, A; Elrayess, MA; Phoenix, DA; Sun, X; Wan, KW; Wang, Q; Zhang, M; Zhang, Z, 2019) |
| "Vanadium pentoxide (V2O5) is a component of PM derived from fuel combustion as well as a source of occupational exposure in humans." | 1.36 | Vanadium pentoxide induces pulmonary inflammation and tumor promotion in a strain-dependent manner. ( Bauer, AK; Rondini, EA; Walters, DM, 2010) |
| "Early detection of lung cancer is problematic due to the lack of a marker with high diagnosis sensitivity and specificity." | 1.35 | Proteomic analysis of serum in lung cancer induced by 3-methylcholanthrene. ( Chen, H; Li, M; Liu, M; Xia, D; Yang, F; Ye, B; Zhang, Y, 2009) |
| "Spermine-BBI was administered to animals for only the first 2 months of the 4-month assay period before animal sacrifice, so the results suggest that the effects of spermine-BBI on the parameters related to heart disease are long-lasting, as are the effects of both pBBI and spermine-BBI on lung tumorigenesis." | 1.32 | Effects of spermine-conjugated Bowman-Birk inhibitor (spermine-BBI) on carcinogenesis and cholesterol biosynthesis in mice. ( Kennedy, AR; Kritchevsky, D; Shen, WC, 2003) |
| "The emodin treatment induced P450s 1A1 and 1B1 mRNA in human lung carcinoma NCI-H322 and breast cancer MCF-7 cells." | 1.31 | Induction of cytochromes P450 1A1 and 1B1 by emodin in human lung adenocarcinoma cell line CL5. ( Chen, TL; Ueng, TH; Wang, HW; Yang, PC, 2001) |
| " The transgenic mice exhibited significantly reduced lung tumor multiplicity (tumor number) in proportion to transgene expression, a dose-response effect." | 1.31 | Manipulation of pulmonary prostacyclin synthase expression prevents murine lung cancer. ( Gao, B; Geraci, MW; Gesell, TL; Golpon, HA; Hoshikawa, Y; Keith, RL; Malkinson, AM; Miller, YE; Moore, MD; Nemenoff, RA, 2002) |
| "implants of human ovarian cancer (IGROV) cells were treated 3 days later with i." | 1.29 | In vivo antitumor activity of T cells redirected with chimeric antibody/T-cell receptor genes. ( Cowherd, R; Eshhar, Z; Hwu, P; Rosenberg, SA; Shafer, GE; Treisman, J; Yang, JC, 1995) |
| "This chemotherapy model has important pharmacokinetic advantages and causes an increased treatment response for pulmonary metastatic sarcoma with minimal systemic and local toxicity as compared with systemic doxorubicin administration." | 1.29 | Pulmonary artery perfusion of doxorubicin with blood flow occlusion: pharmacokinetics and treatment in a metastatic sarcoma model. ( Blumberg, D; Burt, ME; Hochwald, SN; Ng, B; Port, JL; Wang, HY, 1995) |
| "When injected i." | 1.28 | Fibrosarcoma cells transduced with the IL-6 gene exhibited reduced tumorigenicity, increased immunogenicity, and decreased metastatic potential. ( Blaese, RM; Brandt, S; Coale, MM; Levy, AT; Liotta, LA; Mullen, CA; Stetler-Stevenson, WG, 1992) |
| " The bioavailability of UK-21 given p." | 1.28 | Antitumor activity of two novel low immunosuppressive fluoropyrimidines UK-21 and UK-25. ( Kato, T; Kitaichi, K; Koda, A; Mori, H; Sakamoto, O, 1992) |
| "Ilmofosine is a cytostatic/cytotoxic thioether phospholipid derivative." | 1.28 | In vivo antitumor activity of ilmofosine. ( Bicker, U; Herrmann, DB; Opitz, HG; Pahlke, W, 1990) |
| "Cell lines from metastases and primary tumors were heterogeneous in tumorigenicity, growth rate, metastatic potential (spontaneous), and colonizing capacity (i." | 1.27 | Characterization of spontaneous metastases from autochthonous 3-methylcholanthrene-induced tumors. ( Bottazzi, B; Giavazzi, R; Mantovani, A; Taraboletti, G, 1986) |
| " The difference held for offspring of both (C57BL/6 X DBA)F1 and DBA mothers and it was of statistical significance for one or both sexes at most dosage levels." | 1.27 | Fetal mouse susceptibility to transplacental lung and liver carcinogenesis by 3-methylcholanthrene: positive correlation with responsiveness to inducers of aromatic hydrocarbon metabolism. ( Anderson, LM; Jones, AB; Ohshima, M; Riggs, CW, 1985) |
| "The basis of this increase in cancer rates in blacks over the last two decades is unknown." | 1.26 | Release of lymphotoxin by control and chemical carcinogen-treated lymphocyte cultures derived from black healthy subjects and cancer patients. ( Alfred, LJ; Bradley, C; Gill, G; Mandal, AK; Richardson, M; Venkatesan, N; Williams, C, 1982) |
| " The dosing schedule and total dose of DMN or MCA or DMN + MCA received were identical to those used by other investigators in their syncarcinogenesis bioassay study in Swiss mice." | 1.26 | Comparative pulmonary tumorigenesis in DBA/2J and C57Bl/6J mice by administration of 3-methylcholanthrene and dimethylnitrosamine singly and combined. ( Arcos, JC; Argus, MF; Hoch-Ligeti, C, 1982) |
| "Hypercholesteremia was also associated with a decreased antibody response to sheep erythrocytes in vivo, but dit not appear to exert a detrimental effect on B- or T-cell blastogenesis when tested in vitro." | 1.26 | Inhibition of host resistance by nutritional hypercholesteremia. ( Cohen, D; Kaplan, AM; Kos, WL; Loria, RM; Snodgrass, MJ; Thorpe, TG, 1979) |
| " However, severe alopecia was observed in mice treated with this agent at dosage level near the LD50." | 1.26 | Antitumor activity of prumycin. ( Ito, K; Marumo, H; Nakamura, N; Okubo, S; Omura, S; Tanaka, M, 1979) |
| "Thus, trauma and dextran 1000 stimulate metastasis formation by different mechanisms." | 1.26 | Metastasis formation after intravenous tumour cell injection in thrombocytopenic rats. ( Ivarsson, L, 1976) |
| "The lung cancers were also not randomly distributed in DBA/2Cum X F1 backcross progeny since significantly more lung cancers were found in AHH-responsive progeny than in AHH non-responsive mice." | 1.26 | Correlation of inducibility of aryl hydrocarbon hydroxylase with susceptibility to 3-methylcholanthrene-induced lung cancers. ( Billups, LH; Henry, CJ; Kouri, RE; Rude, TH; Sass, B; Whitmire, CE, 1980) |
| "Early metastases to the lung was associated with low levels of tumor-specific immunogenicity and high levels of H-2 antigenicity." | 1.25 | Antigenic specificities on murine sarcoma cells. Reciprocal relationship between normal transplantation antigens (H-2) and tumor-specific immunogenicity. ( Haywood, GR; McKhann, CF, 1971) |
| "Genuine tumors soon arise, multiple benign adenomas sometimes appearing within 3 weeks, and indubitable carcinomas a few weeks later." | 1.23 | The neoplastic potentialities of mouse embryo tissues; the tumors elicited with methylcholanthrene from pulmonary epithelium. ( SMITH, WE, 1950) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 217 (73.56) | 18.7374 |
| 1990's | 40 (13.56) | 18.2507 |
| 2000's | 22 (7.46) | 29.6817 |
| 2010's | 15 (5.08) | 24.3611 |
| 2020's | 1 (0.34) | 2.80 |
| Authors | Studies |
|---|---|
| Li, M | 2 |
| Li, X | 2 |
| Goldsmith, JR | 1 |
| Shi, S | 1 |
| Zhang, L | 1 |
| Zamani, A | 1 |
| Wan, L | 1 |
| Sun, H | 1 |
| Li, T | 1 |
| Yu, J | 1 |
| Etwebi, Z | 1 |
| Bou-Dargham, MJ | 1 |
| Chen, YH | 1 |
| Falcone, LM | 2 |
| Erdely, A | 3 |
| Salmen, R | 2 |
| Keane, M | 2 |
| Battelli, L | 1 |
| Kodali, V | 1 |
| Bowers, L | 1 |
| Stefaniak, AB | 1 |
| Kashon, ML | 2 |
| Antonini, JM | 3 |
| Zeidler-Erdely, PC | 3 |
| Sedlacek, AL | 1 |
| Younker, TP | 1 |
| Zhou, YJ | 1 |
| Borghesi, L | 1 |
| Shcheglova, T | 1 |
| Mandoiu, II | 1 |
| Binder, RJ | 1 |
| Zhang, M | 1 |
| Wang, Q | 2 |
| Wan, KW | 1 |
| Ahmed, W | 1 |
| Phoenix, DA | 1 |
| Zhang, Z | 1 |
| Elrayess, MA | 1 |
| Elhissi, A | 1 |
| Sun, X | 1 |
| Meighan, TG | 2 |
| Battelli, LA | 2 |
| von Scheidt, B | 1 |
| Leung, PS | 1 |
| Yong, MC | 1 |
| Zhang, Y | 3 |
| Towne, JE | 1 |
| Smyth, MJ | 2 |
| Teng, MW | 1 |
| Sun, L | 1 |
| Yang, X | 1 |
| Ma, X | 1 |
| Li, Q | 1 |
| Chen, Y | 1 |
| Liu, Y | 1 |
| Zhang, D | 1 |
| Xiang, R | 1 |
| Wei, Y | 1 |
| Han, J | 1 |
| Duan, Y | 1 |
| McKinney, W | 1 |
| Stone, S | 1 |
| Cumpston, A | 1 |
| Cumpston, J | 1 |
| Andrews, RN | 1 |
| Kashon, M | 1 |
| Liu, WB | 4 |
| Liu, JY | 4 |
| Ao, L | 4 |
| Zhou, ZY | 4 |
| Zhou, YH | 4 |
| Cui, ZH | 4 |
| Yang, H | 1 |
| Cao, J | 4 |
| Efeyan, A | 1 |
| Murga, M | 1 |
| Martinez-Pastor, B | 1 |
| Ortega-Molina, A | 1 |
| Soria, R | 1 |
| Collado, M | 1 |
| Fernandez-Capetillo, O | 1 |
| Serrano, M | 1 |
| Ye, B | 1 |
| Chen, H | 3 |
| Xia, D | 1 |
| Liu, M | 3 |
| Yang, F | 1 |
| Fritz, JM | 1 |
| Dwyer-Nield, LD | 3 |
| Russell, BM | 1 |
| Malkinson, AM | 8 |
| JAFFE, WG | 1 |
| Rondini, EA | 1 |
| Walters, DM | 1 |
| Bauer, AK | 1 |
| Yuan, XY | 2 |
| Xiang, YL | 2 |
| Vikis, HG | 1 |
| Gelman, AE | 1 |
| Franklin, A | 1 |
| Stein, L | 1 |
| Rymaszewski, A | 1 |
| Zhu, J | 1 |
| Liu, P | 1 |
| Tichelaar, JW | 1 |
| Krupnick, AS | 1 |
| You, M | 1 |
| Karoor, V | 1 |
| Le, M | 1 |
| Merrick, D | 1 |
| Fagan, KA | 1 |
| Dempsey, EC | 1 |
| Miller, YE | 2 |
| Chow, MT | 1 |
| Sceneay, J | 1 |
| Paget, C | 1 |
| Wong, CS | 1 |
| Duret, H | 1 |
| Tschopp, J | 1 |
| Möller, A | 1 |
| Kim, JA | 1 |
| Shu, S | 2 |
| Li, H | 2 |
| Chen, F | 1 |
| Yu, L | 1 |
| Liu, X | 1 |
| HESTON, WE | 1 |
| DERINGER, MK | 1 |
| MILLER, EW | 1 |
| PYBUS, FC | 1 |
| DUMBELL, K | 1 |
| ROUS, P | 1 |
| BLACKLOCK, JW | 1 |
| KOECKE, HU | 1 |
| RIGDON, RH | 3 |
| ZALDIVAR, RS | 1 |
| KELLY, MG | 2 |
| NEWTON, WL | 1 |
| O'GARA, RW | 2 |
| BROWN, CE | 2 |
| MIYOSHI, I | 1 |
| GHOSE, T | 1 |
| KLEIN, M | 1 |
| GROSS, P | 1 |
| POEL, W | 1 |
| HAYASHI, N | 1 |
| NISHIZUKA, Y | 1 |
| NAKAKUKI, K | 1 |
| HIRAKI, K | 1 |
| YASUHIRA, K | 5 |
| MIZUKAMI, T | 1 |
| CAMPBELL, JS | 1 |
| YANG, YH | 1 |
| BOLTON, JD | 1 |
| MOGILA, MT | 1 |
| DOBRYNIN, IaV | 1 |
| McANELLY, SM | 1 |
| Kennedy, AR | 3 |
| Kritchevsky, D | 1 |
| Shen, WC | 2 |
| SMITH, WE | 2 |
| SHIMKIN, MB | 6 |
| McCLELLAND, JN | 1 |
| Gorshkova, EV | 1 |
| Kaledin, VI | 1 |
| Kobzev, VF | 1 |
| Merkulova, TI | 1 |
| O'Donnell, EP | 1 |
| Zerbe, LK | 1 |
| Kisley, LR | 1 |
| Umemura, T | 1 |
| Kodama, Y | 2 |
| Nishikawa, A | 1 |
| Hioki, K | 1 |
| Nomura, T | 2 |
| Kanki, K | 1 |
| Kuroiwa, Y | 1 |
| Ishii, Y | 1 |
| Kurokawa, Y | 1 |
| Hirose, M | 1 |
| Jennings-Gee, JE | 1 |
| Moore, JE | 1 |
| Xu, M | 1 |
| Dance, ST | 1 |
| Kock, ND | 1 |
| McCoy, TP | 1 |
| Carr, JJ | 1 |
| Miller, MS | 8 |
| Peebles, KA | 1 |
| Wang, IC | 1 |
| Meliton, L | 1 |
| Tretiakova, M | 1 |
| Costa, RH | 1 |
| Kalinichenko, VV | 1 |
| Kalin, TV | 1 |
| Marchant, J | 1 |
| Feit, J | 2 |
| Svejda, J | 1 |
| Hoffmann, M | 2 |
| Hirao, F | 10 |
| Fujisawa, T | 3 |
| Tsubura, E | 4 |
| Akamatsu, Y | 3 |
| Yamamura, Y | 8 |
| Vlasov, V | 3 |
| Uzunov, P | 2 |
| Wang, N | 2 |
| Yu, SH | 1 |
| Liener, IE | 1 |
| Hebbel, RP | 1 |
| Eaton, JW | 1 |
| McKhann, CF | 3 |
| Yoshida, Y | 1 |
| Hattori, A | 1 |
| Mori, M | 1 |
| Tanaka, T | 4 |
| Yamagishi, H | 3 |
| Inaba, S | 3 |
| Kobayashi, M | 2 |
| Kurioka, H | 1 |
| Naito, K | 1 |
| Hashimoto, I | 1 |
| Benfield, JR | 7 |
| Shors, EC | 2 |
| Hammond, WG | 7 |
| Paladugu, RR | 1 |
| Cohen, AH | 1 |
| Jensen, T | 1 |
| Fu, PC | 1 |
| Pak, HY | 3 |
| Teplitz, RL | 4 |
| Tian, HS | 2 |
| Liu, MQ | 3 |
| Gao, WQ | 2 |
| Zuo, RD | 2 |
| Xiong, YY | 1 |
| Chen, ZF | 1 |
| Rasmussen, RE | 1 |
| Anderson, J | 1 |
| Kinkead, ER | 1 |
| MacEwen, JD | 1 |
| Bruner, RH | 1 |
| Wrba, H | 1 |
| Yu, S | 1 |
| Paladugu, R | 1 |
| Edel, G | 1 |
| Grundmann, E | 1 |
| Tsuchiya, K | 2 |
| Oka, T | 2 |
| Jessup, JM | 1 |
| Kahan, BD | 3 |
| LeGrue, SJ | 1 |
| Rutzky, L | 1 |
| Pellis, NR | 3 |
| York, RG | 1 |
| Stemmer, K | 1 |
| Manson, JM | 1 |
| Yoshimoto, T | 4 |
| Namba, M | 2 |
| Ichinose, Y | 1 |
| Yasumoto, K | 2 |
| Tanaka, K | 1 |
| Yaita, H | 1 |
| Nomoto, K | 2 |
| Fray, A | 1 |
| Lespinats, G | 1 |
| Scheinmann, P | 1 |
| Salomon, JC | 1 |
| Paupe, J | 1 |
| Canu, P | 1 |
| Villet, R | 1 |
| Burtin, C | 1 |
| Liu, JL | 1 |
| Stepan'ian, LI | 2 |
| Vakhtin, IuB | 4 |
| Warren, S | 1 |
| Chute, RN | 1 |
| Federman, M | 1 |
| Diwan, BA | 1 |
| Blackman, KE | 1 |
| Varani, J | 1 |
| Lovett, EJ | 2 |
| Alfred, LJ | 1 |
| Venkatesan, N | 1 |
| Mandal, AK | 1 |
| Gill, G | 1 |
| Richardson, M | 1 |
| Williams, C | 1 |
| Bradley, C | 1 |
| Seyama, T | 1 |
| Kamiya, K | 1 |
| Yokoro, K | 1 |
| Grdina, DJ | 3 |
| Auer, G | 2 |
| Ono, J | 2 |
| Nasiell, M | 2 |
| Caspersson, T | 1 |
| Kato, H | 2 |
| Konaka, C | 2 |
| Hayata, Y | 3 |
| Iimura, I | 1 |
| Matsushima, Y | 1 |
| Tahara, M | 1 |
| Lei, J | 1 |
| Hunter, N | 3 |
| Argus, MF | 3 |
| Hoch-Ligeti, C | 2 |
| Arcos, JC | 3 |
| Kinoshita, K | 2 |
| Hashimoto, K | 1 |
| Takahashi, G | 3 |
| Anderson, LM | 5 |
| Priest, LJ | 1 |
| Henry, CJ | 2 |
| Billups, LH | 2 |
| Avery, MD | 1 |
| Rude, TH | 2 |
| Dansie, DR | 1 |
| Lopez, A | 1 |
| Sass, B | 2 |
| Whitmire, CE | 4 |
| Kouri, RE | 2 |
| Zhou, DX | 1 |
| Zou, ZY | 1 |
| Zhang, HT | 1 |
| Ishibashi, T | 1 |
| Yamada, H | 1 |
| Harada, S | 1 |
| Harada, Y | 2 |
| Miyazaki, N | 1 |
| Takamoto, M | 1 |
| Watanabe, K | 1 |
| Sakatani, M | 1 |
| Nishikawa, H | 2 |
| Ogura, T | 3 |
| Azuma, I | 2 |
| Tesluk, H | 1 |
| Hwu, P | 1 |
| Yang, JC | 1 |
| Cowherd, R | 1 |
| Treisman, J | 1 |
| Shafer, GE | 1 |
| Eshhar, Z | 1 |
| Rosenberg, SA | 3 |
| Wang, X | 1 |
| Witschi, H | 4 |
| Yu, LY | 1 |
| Shu, QB | 1 |
| Hamuro, J | 1 |
| Takatsuki, F | 1 |
| Suga, T | 1 |
| Kikuchi, T | 1 |
| Suzuki, M | 1 |
| Wang, HY | 2 |
| Ng, B | 4 |
| Ahrens, C | 1 |
| Burt, M | 2 |
| Weksler, B | 1 |
| Blumberg, D | 2 |
| Lenert, JT | 1 |
| Fong, Y | 3 |
| Burt, ME | 3 |
| Ekrami, H | 1 |
| Mass, MJ | 1 |
| Jeffers, AJ | 1 |
| Ross, JA | 1 |
| Nelson, G | 1 |
| Galati, AJ | 1 |
| Stoner, GD | 4 |
| Nesnow, S | 1 |
| Heniford, BT | 1 |
| Edwards, MJ | 1 |
| Wilson, MA | 1 |
| Klar, EA | 1 |
| Doak, KW | 1 |
| Miller, FN | 1 |
| Tuttle, TM | 1 |
| McCrady, CW | 1 |
| Inge, TH | 1 |
| Salour, M | 1 |
| Bear, HD | 1 |
| Port, JL | 1 |
| Hochwald, SN | 1 |
| Forkert, PG | 1 |
| Jackson, AC | 1 |
| Parkinson, A | 1 |
| Chen, S | 1 |
| Mullen, CA | 2 |
| Petropoulos, D | 1 |
| Lowe, RM | 1 |
| Wessner, LL | 2 |
| Fan, M | 1 |
| Schaeffer, DO | 1 |
| McEntee, MF | 2 |
| Ruskie, S | 1 |
| Carter, J | 1 |
| Pittinger, S | 1 |
| Kovatch, RM | 2 |
| Riggs, CW | 3 |
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6 reviews available for 3-methylcholanthrene and Lung Neoplasms
| Article | Year |
|---|---|
Differential sensitivity to lung tumorigenesis following transplacental exposure of mice to polycyclic hydrocarbons, heterocyclic amines, and lung tumor promoters.
Topics: Adenocarcinoma; Adenoma; Animals; Aryl Hydrocarbon Hydroxylases; Butylated Hydroxytoluene; Carcinoge | 2000 |
[Basic research on lung cancer].
Topics: Animals; Diethylnitrosamine; Disease Models, Animal; Genes, Tumor Suppressor; Growth Substances; His | 2002 |
[Some contributions by chemical carcinogenesis--what is the animal model of human cancer? (author's transl)].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Cricetinae; Disease Models, Animal; Dogs; | 1978 |
Immune surveillance system: its failure and activation.
Topics: Aged; Animals; Antibodies; Breast Neoplasms; Cell Transformation, Neoplastic; Complement System Prot | 1977 |
Cocarcinogenesis.
Topics: 2-Acetylaminofluorene; Animals; Carcinogens; Cell Transformation, Viral; Cocarcinogenesis; Diet; Gas | 1979 |
A critical review of experiments in chemical carcinogensis using newborn animals.
Topics: Age Factors; Animals; Animals, Newborn; Anthracenes; Benz(a)Anthracenes; Carcinogens; Cricetinae; Ha | 1968 |
289 other studies available for 3-methylcholanthrene and Lung Neoplasms
| Article | Year |
|---|---|
Decoupling tumor cell metastasis from growth by cellular pilot protein TNFAIP8.
Topics: Animals; Apoptosis Regulatory Proteins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Diethyl | 2021 |
Pulmonary toxicity and lung tumorigenic potential of surrogate metal oxides in gas metal arc welding-stainless steel fume: Iron as a primary mediator versus chromium and nickel.
Topics: Air Pollutants, Occupational; Animals; Calcium Compounds; Carcinogenesis; Carcinogens; Chromates; Ch | 2018 |
CD91 on dendritic cells governs immunosurveillance of nascent, emerging tumors.
Topics: Animals; Antigen Presentation; Antigens, Neoplasm; Carcinoma, Squamous Cell; Cross-Priming; Dendriti | 2019 |
Liposome mediated-CYP1A1 gene silencing nanomedicine prepared using lipid film-coated proliposomes as a potential treatment strategy of lung cancer.
Topics: A549 Cells; Animals; Cytochrome P-450 CYP1A1; Gene Silencing; Humans; Lipids; Liposomes; Lung Neopla | 2019 |
Lung tumor promotion by chromium-containing welding particulate matter in a mouse model.
Topics: Air Pollutants, Occupational; Animals; Chromium; Cocarcinogenesis; Lung Neoplasms; Male; Methylchola | 2013 |
Combined anti-CD40 and anti-IL-23 monoclonal antibody therapy effectively suppresses tumor growth and metastases.
Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protoco | 2014 |
Activation of liver X receptor inhibits the development of pulmonary carcinomas induced by 3-methylcholanthrene and butylated hydroxytoluene in BALB/c mice.
Topics: Animals; Butylated Hydroxytoluene; Carcinogens; Carcinoma; Humans; Interferon-gamma; Liver X Recepto | 2016 |
Inhalation of gas metal arc-stainless steel welding fume promotes lung tumorigenesis in A/J mice.
Topics: Administration, Inhalation; Air Pollutants, Occupational; Animals; Disease Models, Animal; Inhalatio | 2017 |
Dynamic changes in DNA methylation during multistep rat lung carcinogenesis induced by 3-methylcholanthrene and diethylnitrosamine.
Topics: Animals; Azacitidine; Cell Line; Cocarcinogenesis; Cyclin-Dependent Kinase Inhibitor p15; Cyclin-Dep | 2009 |
Limited role of murine ATM in oncogene-induced senescence and p53-dependent tumor suppression.
Topics: Adenoma; Animals; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cellular Senescence; | 2009 |
Proteomic analysis of serum in lung cancer induced by 3-methylcholanthrene.
Topics: Animals; Biomarkers, Tumor; Disease Models, Animal; Female; Humans; Lung Neoplasms; Male; Methylchol | 2009 |
The Kras mutational spectra of chemically induced lung tumors in different inbred mice mimics the spectra of KRAS mutations in adenocarcinomas in smokers versus nonsmokers.
Topics: Adenocarcinoma; Animals; Butylated Hydroxytoluene; Codon; Humans; Lung Neoplasms; Methylcholanthrene | 2010 |
Possible linkage between the development of local tumors and pulmonary adenomas induced by methyl-cholanthrene in non-inbred mice.
Topics: Adenoma; Animals; Benz(a)Anthracenes; Lung; Lung Neoplasms; Methylcholanthrene; Mice; Mice, Inbred S | 1947 |
Vanadium pentoxide induces pulmonary inflammation and tumor promotion in a strain-dependent manner.
Topics: Air Pollutants; Animals; Carcinogens; Chemokines; Disease Models, Animal; Genetic Predisposition to | 2010 |
Epigenetic silencing of cell cycle regulatory genes during 3-methylcholanthrene and diethylnitrosamine-induced multistep rat lung cancer.
Topics: Animals; Carcinoma; Cell Cycle; CpG Islands; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent | 2010 |
CpG island hypermethylation of multiple tumor suppressor genes associated with loss of their protein expression during rat lung carcinogenesis induced by 3-methylcholanthrene and diethylnitrosamine.
Topics: Acid Anhydride Hydrolases; Animals; Apoptosis Regulatory Proteins; Calcium-Calmodulin-Dependent Prot | 2010 |
Aberrant methylation accounts for cell adhesion-related gene silencing during 3-methylcholanthrene and diethylnitrosamine induced multistep rat lung carcinogenesis associated with overexpression of DNA methyltransferases 1 and 3a.
Topics: Animals; Azacitidine; Cadherins; Cell Adhesion; Cell Adhesion Molecules; Cell Transformation, Neopla | 2011 |
Neutrophils are required for 3-methylcholanthrene-initiated, butylated hydroxytoluene-promoted lung carcinogenesis.
Topics: Animals; Butylated Hydroxytoluene; Carcinogens; Cell Transformation, Neoplastic; Female; Flow Cytome | 2012 |
Alveolar hypoxia promotes murine lung tumor growth through a VEGFR-2/EGFR-dependent mechanism.
Topics: Animals; Antioxidants; Basic Helix-Loop-Helix Transcription Factors; Biomarkers, Tumor; Blotting, We | 2012 |
NLRP3 suppresses NK cell-mediated responses to carcinogen-induced tumors and metastases.
Topics: Adenocarcinoma; Animals; Carrier Proteins; CD11b Antigen; Chemokine CCL5; Chemokine CXCL9; Fibrosarc | 2012 |
Adoptive immunotherapy.
Topics: Animals; Cell Line; Female; Humans; Immunotherapy, Adoptive; Interleukin-2; Killer Cells, Lymphokine | 2003 |
Expression of inflammation related enzymes during experimental rat lung carcinogenesis.
Topics: Animals; Carcinogens; Carcinoma, Squamous Cell; Cyclooxygenase 2; Female; Immunohistochemistry; Isoe | 2002 |
Induction of pulmonary tumors in guinea pigs by intravenous injection of methylcholanthrene and dibenzanthracene.
Topics: Animals; Benz(a)Anthracenes; Guinea Pigs; Injections, Intravenous; Lung Neoplasms; Methylcholanthren | 1952 |
The effect of methylcholanthrene on the incidence of lung tumours in two inbred strains of mice and their reciprocal hybrids.
Topics: Animals; Incidence; Lung Neoplasms; Methylcholanthrene; Mice; Mice, Inbred Strains; Neoplasms, Exper | 1954 |
Are carcinogens responsible for the superimposed neoplastic changes occurring in mouse tumor cells? The effect of methylcholanthrene and urethane on pulmonary adenomas and of methylcholanthrene on mammary carcinomas.
Topics: Adenoma; Animals; Breast Neoplasms; Carcinogens; Humans; Lung; Lung Neoplasms; Methylcholanthrene; M | 1955 |
The production of lung tumours in rats by 3:4 benzpyrene methylcholanthrene and the condensate from cigarette smoke.
Topics: Animals; Benzopyrenes; Lung Neoplasms; Methylcholanthrene; Neoplasms, Experimental; Nicotiana; Rats; | 1957 |
[Research on sensitivity of the alveolar epithelial cells in mouse lung to carcinogenic substance (methylcholanthrene)].
Topics: Alveolar Epithelial Cells; Animals; Carcinogens; Lung Neoplasms; Methylcholanthrene; Mice | 1958 |
Pulmonary neoplasms produced by methyl-cholanthrene in the white Pekin duck.
Topics: Animals; Benz(a)Anthracenes; Ducks; Lung Neoplasms; Methylcholanthrene; Neoplasms, Experimental | 1961 |
Effect of urethane of pulmonary tumors produced by methylcholanthrene.
Topics: Humans; Lung Neoplasms; Methylcholanthrene; Urethane | 1963 |
Cancer research in Chile.
Topics: Antineoplastic Agents; Chile; Hexestrol; Lung Neoplasms; Mechlorethamine; Methylcholanthrene; Neopla | 1962 |
SUSCEPTIBILITY OF NEWBORN GERM-FREE MICE TO TUMOR INDUCTION BY 3-METHYLCHOLANTHRENE.
Topics: Animals; Germ-Free Life; Leukemia; Leukemia, Experimental; Lung Neoplasms; Methylcholanthrene; Mice; | 1963 |
CARCINOMA OF RAT LUNG FROM INTRAPLEURAL METHYLCHOLANTHRENE.
Topics: Carcinoma; Lung; Lung Neoplasms; Methylcholanthrene; Neoplasms; Neoplasms, Experimental; Pathology; | 1963 |
ACCELERATION OF THE DEVELOPMENT OF LEUKEMIA AND INDUCTION OF TUMORS IN AKR MICE BY NEONATAL INJECTION OF 20-METHYLCHOLANTHRENE.
Topics: Adenoma; Animals; Carcinogens; Leukemia; Leukemia, Experimental; Leukemia, Lymphoid; Lung Neoplasms; | 1963 |
THE EFFECT OF CORTISONE ON CARCINOGENESIS AND METASTATIC SPREAD OF AUTOCHTHONOUS TUMORS.
Topics: Adenocarcinoma; Animals; Carcinogenesis; Cortisone; Fibrosarcoma; Lung Neoplasms; Methylcholanthrene | 1963 |
SUSCEPTIBILITY OF STRAIN B6AF1-J HYBRID INFANT MICE TO TUMORIGENESIS WITH 1,2-BENZANTHRACENE, DEOXYCHOLIC ACID, AND 3-METHYLCHOLANTHRENE.
Topics: Animals; Animals, Newborn; Benz(a)Anthracenes; Bile Acids and Salts; Carcinogenesis; Carcinogens; Ca | 1963 |
PULMONARY ADENOMA. THE FIBROGENIC POTENTIAL OF ITS EPITHELIUM.
Topics: Adenoma; Epithelium; Lung Neoplasms; Methylcholanthrene; Mice; Neoplasms; Neoplasms, Experimental; P | 1964 |
[ELECTRON MICROSCOPIC STUDIES ON THE EXPERIMENTAL LUNG TUMOR IN MOUSE].
Topics: Adenoma; Animals; Electrons; Lung Neoplasms; Methylcholanthrene; Mice; Microscopy; Microscopy, Elect | 1963 |
EFFECT OF 20-METHYLCHOLANTHRENE GIVEN AT BIRTH ON TUMOR DEVELOPMENT IN TWO HIGH-LEUKEMIA STRAINS OF MICE, AKR AND SL.
Topics: Adenoma; Animals; Animals, Newborn; Histology; Injections, Subcutaneous; Leukemia; Leukemia, Experim | 1964 |
[CONTRIBUTION OF VIRUSES TO NEOPLASM ETIOLOGY].
Topics: Adenocarcinoma; Animals; Leukemia; Leukemia, Experimental; Leukemia, Radiation-Induced; Lung Neoplas | 1964 |
DAMAGE TO THE THYMUS AND OTHER LYMPHOID TISSUES FROM 3-METHYLCHOLANTHRENE, AND SUBSEQUENT THYMOMA PRODUCTION, IN MICE.
Topics: Aging; Body Weight; Electrons; Lung Neoplasms; Lymph Nodes; Lymphoid Tissue; Methylcholanthrene; Mic | 1964 |
CANCER AND MESENCHYMAL SYSTEM.
Topics: Animals; Benzopyrenes; Carcinogens; Carcinoma; Carcinoma, Ehrlich Tumor; Connective Tissue; Cortison | 1964 |
MURINE LUNG ADENOMAS INDUCED BY INTRAVAGINAL CARCINOGEN.
Topics: Adenoma; Animals; Carcinogens; Female; Humans; Lung Neoplasms; Methylcholanthrene; Mice; Neoplasms; | 1965 |
[On the changes in the morphology of explants of connective tissue in rats under the influence of methvlcholanthrene and extract of human lung tumor].
Topics: Animals; Connective Tissue; Humans; Lung Neoplasms; Methylcholanthrene; Neoplasms, Experimental; Rat | 1960 |
Lesions in ducks given methylcholanthrene. Lesions in respiratory tract with intratracheal administration.
Topics: Animals; Ducks; Lung Neoplasms; Methylcholanthrene; Neoplasms, Experimental; Respiratory System | 1961 |
Effects of spermine-conjugated Bowman-Birk inhibitor (spermine-BBI) on carcinogenesis and cholesterol biosynthesis in mice.
Topics: Animals; Anticarcinogenic Agents; Anticholesteremic Agents; Carcinogens; Cholesterol; Heart Diseases | 2003 |
The neoplastic potentialities of mouse embryo tissues; the tumors elicited with methylcholanthrene from pulmonary epithelium.
Topics: Animals; Carcinogens; Lung Neoplasms; Methylcholanthrene; Mice; Neoplasms | 1950 |
Induced pulmonary tumors in mice; analysis of dose response data with methylcholanthrene.
Topics: Animals; Lung; Lung Neoplasms; Methylcholanthrene; Mice; Neoplasms | 1949 |
Codon 12 region of mouse K-ras gene is the site for in vitro binding of transcription factors GATA-6 and NF-Y.
Topics: Animals; Base Sequence; Binding Sites; CCAAT-Binding Factor; Codon; Ethylnitrosourea; GATA6 Transcri | 2005 |
Quantitative analysis of early chemically-induced pulmonary lesions in mice of varying susceptibilities to lung tumorigenesis.
Topics: Adenoma; Animals; Butylated Hydroxytoluene; Cell Transformation, Neoplastic; Disease Susceptibility; | 2006 |
Nine-week detection of six genotoxic lung carcinogens using the rasH2/BHT mouse model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alkylating Agents; Animals; Antioxidants; Benzo(a)pyrene; Butylate | 2006 |
Strain-specific induction of murine lung tumors following in utero exposure to 3-methylcholanthrene.
Topics: Animals; Female; Fetal Development; Fetus; Genes, ras; Inbreeding; Lung Neoplasms; Methylcholanthren | 2006 |
Altered expression of splicing factor, heterogeneous nuclear ribonucleoprotein A2/B1, in mouse lung neoplasia.
Topics: Animals; Biomarkers, Tumor; Butylated Hydroxytoluene; Carcinogens; Cell Line; Cell Proliferation; Ce | 2007 |
Transgenic expression of the forkhead box M1 transcription factor induces formation of lung tumors.
Topics: Adenoma; Animals; Butylated Hydroxytoluene; Cyclooxygenase 2; DNA Replication; Forkhead Box Protein | 2008 |
The effects of different social conditions on breast cancer induction in three genetic types of mice by dibenz[a,h]anthracene and a comparison with breast carcinogenesis by 3-methylcholanthrene.
Topics: Animals; Behavior, Animal; Benz(a)Anthracenes; Estrogens; Female; Genetics; Lactation; Liver Neoplas | 1967 |
Experimentally produced precancerosis of the lung in rats.
Topics: Animals; Carcinoma, Squamous Cell; Lung Neoplasms; Metaplasia; Methylcholanthrene; Rats | 1967 |
Experimental cancerous changes in the lung induced by chemical carcinogens in rabbits.
Topics: Amyloidosis; Animals; Bronchi; Female; Lung Neoplasms; Male; Methylcholanthrene; Neoplasms, Experime | 1967 |
[Immunological reactivity of mice with transplanted lung tumors obtained via organ culture].
Topics: Adenocarcinoma; Animals; Antibody-Producing Cells; Benzo(a)pyrene; Benzopyrenes; Lung; Lung Neoplasm | 1984 |
Characterization of high- and low-metastatic clones derived from a methylcholanthrene-induced murine fibrosarcoma.
Topics: Animals; Antigens, Neoplasm; Cell Adhesion; Chromosomes; Clone Cells; Epitopes; Fibrosarcoma; Geneti | 1982 |
Transformation of human lung cells by 3-methylcholanthrene in vitro.
Topics: Antibodies, Neoplasm; Cell Transformation, Neoplastic; Cells, Cultured; Female; Fetus; Humans; Kerat | 1983 |
[Specific active immunotherapy of murine methylcholanthrene-induced sarcoma using a partially purified soluble tumor specific transplantation antigens].
Topics: Animals; Antigens, Neoplasm; Epitopes; Histocompatibility Antigens; Lung Neoplasms; Male; Methylchol | 1983 |
A clinically relevant canine lung cancer model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Delayed-Action | 1981 |
[Electron microscopic study of nuclear inclusions in the cells of experimental malignant lung tumors].
Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Cell Nucleus; Lung Neoplasms; Methylcholanthrene; Mice; Mice, | 1982 |
Induction of lung carcinoma by intralobar bronchial instillation of iodized oil in rats.
Topics: Animals; Carcinoma, Squamous Cell; Diethylnitrosamine; Female; Iodized Oil; Lung Neoplasms; Male; Me | 1984 |
Carcinogenesis, benzo[a]pyrene metabolism, and sister chromatid exchanges in lungs of rats after intratracheal 3-methylcholanthrene.
Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Crossing Over, Genetic; Kinetics; Lung; Lung Neo | 1984 |
Experimental cancer prophylaxis.
Topics: Adenoma; Animals; Diterpenes; Ethylnitrosourea; Female; Fetus; Leukemia, Experimental; Lung Neoplasm | 1983 |
The effect of immunity on pulmonary metastasis of a methylcholanthrene-induced fibrosarcoma and three of its clones.
Topics: Animals; Antigens, Neoplasm; Chromosome Aberrations; Clone Cells; Fibrosarcoma; Lung Neoplasms; Meth | 1984 |
A family of epidermoid lung cancer models.
Topics: Animals; Benzo(a)pyrene; Bronchial Neoplasms; Carcinoma, Squamous Cell; Cell Transformation, Neoplas | 1984 |
Selection of liver-colonizing tumor cells from a murine fibrosarcoma induced by methylcholanthrene.
Topics: Animals; Clone Cells; Female; Fibrosarcoma; Injections, Intravenous; Liver Neoplasms; Lung Neoplasms | 1984 |
[The immunotherapeutic effect of partially purified tumor specific transplantation antigen against pulmonary metastasis].
Topics: Animals; Antigens, Neoplasm; Histocompatibility Antigens; Isoelectric Focusing; Lung Neoplasms; Meth | 1984 |
Soluble factors from murine and human tumors induce suppressor cells.
Topics: Adenocarcinoma; Animals; Cell Line; Colonic Neoplasms; Dinitrochlorobenzene; Female; Fibrosarcoma; H | 1984 |
Lung tumorigenesis and hyperplasia in offspring associated with the Ahd allele following in utero exposure to 3-methylcholanthrene.
Topics: Alleles; Animals; Female; Fetus; Genotype; Hyperplasia; Lung; Lung Neoplasms; Male; Maternal-Fetal E | 1984 |
[Experimental lung cancer in rabbits, mice and rats induced by chemical carcinogens (author's transl)].
Topics: 4-Nitroquinoline-1-oxide; Adenocarcinoma; Animals; Benzopyrenes; Carcinoma; Carcinoma, Squamous Cell | 1981 |
Combined treatment of autochthonous 3-methylcholanthrene-induced murine tumors by immunotherapy and radiotherapy.
Topics: Animals; Bacterial Vaccines; Female; Fibrosarcoma; Immunotherapy; Lung Neoplasms; Methylcholanthrene | 1983 |
Selective increased tissue histamine levels in tumour-bearing rodents.
Topics: Animals; Female; Fibrosarcoma; Histamine; Lung Neoplasms; Mammary Neoplasms, Experimental; Methylcho | 1983 |
[The effect of phytohemagglutinin on the induction of pulmonary carcinoma in rats by methylcholanthrene].
Topics: Animals; Female; Immunity, Cellular; Lung Neoplasms; Male; Methylcholanthrene; Neoplasms, Experiment | 1983 |
[Selection for affinity to lung tissue in cell populations of experimental neoplasms].
Topics: Animals; Lung Neoplasms; Lymphoma, Non-Hodgkin; Methylcholanthrene; Mice; Neoplasms, Experimental; R | 1980 |
Mesothelioma relative to asbestos, radiation, and methylcholanthrene.
Topics: Animals; Asbestos; Asbestosis; Female; Lung Neoplasms; Lymphocytes; Macrophages; Male; Mesothelioma; | 1981 |
Carcinogenic effects of combined treatment of inbred mice with 3-methylcholanthrene and 1,2-dimethylhydrazine.
Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Dimethylhydrazines; Drug Interactions; Leukemia, Experim | 1980 |
Phenotypic stability of murine tumor cells in vitro and in vivo.
Topics: Animals; Cell Adhesion; Cell Line; Cell Movement; Female; Fibrosarcoma; Kinetics; Lung Neoplasms; Me | 1982 |
Immunotherapeutic effects of partially purified tumor-specific transplantation antigens on pulmonary metastases of a 3-methylcholanthrene-induced sarcoma in mice: a preliminary report.
Topics: Animals; Antigens, Neoplasm; Female; Lung Neoplasms; Methylcholanthrene; Mice; Mice, Inbred C3H; Neo | 1982 |
Release of lymphotoxin by control and chemical carcinogen-treated lymphocyte cultures derived from black healthy subjects and cancer patients.
Topics: Adult; Aged; Aryl Hydrocarbon Hydroxylases; Black People; Carcinoma, Squamous Cell; Head and Neck Ne | 1982 |
Establishment and immunologic characterization of 3-methylcholanthrene-induced sarcoma cell lines metastasizing widely in mice and exhibiting distinct and selective propensities for the mode of metastasis.
Topics: Animals; Cell Line; Female; Lung Neoplasms; Lymph Nodes; Lymphatic Metastasis; Male; Methylcholanthr | 1982 |
Phase-specific cytotoxicity in vivo of hydroxyurea on murine fibrosarcoma pulmonary nodules.
Topics: Animals; Cell Division; Cell Survival; Female; Fibrosarcoma; Flow Cytometry; Hydroxyurea; Interphase | 1982 |
Reversibility of bronchial cell atypia.
Topics: Animals; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Dogs; Humans; Lung; Lung Neoplasms; Meth | 1982 |
Lung cancer histogenesis following in vivo bronchial injections of 20-methylcholanthrene in dogs.
Topics: Animals; Biopsy; Bronchi; Bronchoscopy; Carcinoma in Situ; Carcinoma, Squamous Cell; DNA; Dogs; Fibe | 1982 |
Cyclic-radiation response of murine fibrosarcoma cells grown as pulmonary nodules.
Topics: Animals; Cell Cycle; Female; Fibrosarcoma; Lung Neoplasms; Methylcholanthrene; Mice; Neoplasm Transp | 1982 |
Comparative pulmonary tumorigenesis in DBA/2J and C57Bl/6J mice by administration of 3-methylcholanthrene and dimethylnitrosamine singly and combined.
Topics: Adenoma; Animals; Dimethylnitrosamine; Lung Neoplasms; Male; Methylcholanthrene; Mice; Mice, Inbred | 1982 |
Gas chromatography-mass spectrometric analysis of 3-methyl-cholanthrene metabolism in vivo.
Topics: Animals; Bile; Feces; Gas Chromatography-Mass Spectrometry; Lung; Lung Neoplasms; Methylcholanthrene | 1980 |
Reduction in the transplacental carcinogenic effect of methylcholanthrene in mice by prior treatment with beta-naphthoflavone.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Carcinogens; Female; Fetus; Flavonoids; Liver; Lung Neo | 1980 |
Lung cancer model system using 3-methylcholanthrene in inbred strains of mice.
Topics: Animals; Disease Models, Animal; Female; Lung Neoplasms; Methylcholanthrene; Mice; Mice, Inbred Stra | 1981 |
[Methodology in establishing an animal model of lung carcinoma. I. Lung carcinoma induced by intratracheal instillation of 3-methylcholanthrene saline suspension (author's transl)].
Topics: Animals; Carcinoma, Squamous Cell; Disease Models, Animal; Female; Lung Neoplasms; Male; Methylchola | 1981 |
Distant metastasis facilitated by BCG: spread of tumour cells injected in the BCG-primed site.
Topics: Animals; BCG Vaccine; Blood Cell Count; Erythrocytes; Female; Fibrosarcoma; Immunity; Iodine Radiois | 1980 |
Correlation of inducibility of aryl hydrocarbon hydroxylase with susceptibility to 3-methylcholanthrene-induced lung cancers.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Biotransformation; Enzyme Induction; Female; Liver; Lung; Lu | 1980 |
Effect of Nocardia rubra cell-wall skeleton on the induction of lung cancer and amyloidosis by 3-methylcholanthrene in rabbits.
Topics: Adenoma; Amyloidosis; Animals; Cell Wall; Female; Hyperplasia; Immunization; Lung Neoplasms; Male; M | 1980 |
Histogenesis of adenosquamous bronchogenic carcinoma.
Topics: Adenocarcinoma; Animals; Benzo(a)pyrene; Carcinogens; Carcinoma, Adenosquamous; Carcinoma, Bronchoge | 1995 |
In vivo antitumor activity of T cells redirected with chimeric antibody/T-cell receptor genes.
Topics: Animals; Antibodies, Monoclonal; Female; Humans; Immunoglobulin Variable Region; Immunotherapy, Adop | 1995 |
Mutations of the Ki-ras protooncogene in 3-methylcholanthrene and urethan-induced and butylated hydroxytoluene-promoted lung tumors of strain A/J and SWR mice.
Topics: Animals; Base Sequence; Butylated Hydroxytoluene; Genes, ras; Lung Neoplasms; Male; Methylcholanthre | 1995 |
[Effect of superoxide dismutase and diethyldithiocarbamate on the induction of squamous cell carcinoma of lung with methylcholanthrene in rats].
Topics: Animals; Carcinoma, Squamous Cell; Cocarcinogenesis; Ditiocarb; Drug Synergism; Female; Lung Neoplas | 1994 |
Synergistic antimetastatic effects of lentinan and interleukin 2 with pre- and post-operative treatments.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; CD4-Positive T-Lymphocytes; CD8-Positive T- | 1994 |
Unilateral pulmonary artery occlusion inhibits growth of metastatic sarcoma in the rat lung.
Topics: Animals; Disease Models, Animal; Fibrosarcoma; Ligation; Lung Neoplasms; Male; Methylcholanthrene; P | 1994 |
Isolated single-lung perfusion with TNF-alpha in a rat sarcoma lung metastases model.
Topics: Animals; Chemotherapy, Cancer, Regional Perfusion; In Vitro Techniques; Lung Neoplasms; Male; Methyl | 1994 |
Cationized Bowman-Birk protease inhibitor as a targeted cancer chemopreventive agent.
Topics: Animals; Anticarcinogenic Agents; Body Weight; Cell Survival; Chromatography, Gel; Chymotrypsin; Inj | 1993 |
Ki-ras oncogene mutations in tumors and DNA adducts formed by benz[j]aceanthrylene and benzo[a]pyrene in the lungs of strain A/J mice.
Topics: Animals; Base Sequence; Benzo(a)pyrene; DNA; Genes, ras; Lung Neoplasms; Methylcholanthrene; Mice; M | 1993 |
Interleukin-8 suppresses the toxicity and antitumor effect of interleukin-2.
Topics: Animals; Chemical and Drug Induced Liver Injury; Edema; Female; Fibrosarcoma; Interleukin-2; Interle | 1994 |
A step section method for full histopathological assessment of carcinogen-affected target tissue during respiratory carcinogenesis.
Topics: Animals; Benzo(a)pyrene; Carcinoma in Situ; Cricetinae; Female; Lung Neoplasms; Male; Metaplasia; Me | 1993 |
gamma-Interferon plays a key role in T-cell-induced tumor regression.
Topics: Adjuvants, Immunologic; Animals; Antibodies; Bryostatins; Female; Immunoglobulin G; Immunotherapy, A | 1993 |
Pulmonary artery perfusion of doxorubicin with blood flow occlusion: pharmacokinetics and treatment in a metastatic sarcoma model.
Topics: Animals; Antibiotics, Antineoplastic; Carcinogens; Chemotherapy, Cancer, Regional Perfusion; Doxorub | 1995 |
Diminished expression of CYP1A1 in urethane-induced lung tumors in strain A/J mice: analysis by in situ hybridization and immunohistochemical methods.
Topics: Animals; Blotting, Northern; Cytochrome P-450 Enzyme System; Female; Gene Expression Regulation, Enz | 1996 |
Treatment of microscopic pulmonary metastases with recombinant autologous tumor vaccine expressing interleukin 6 and Escherichia coli cytosine deaminase suicide genes.
Topics: Adenocarcinoma; Animals; Carcinogens; Colonic Neoplasms; Cyclophosphamide; Cytosine Deaminase; Dimet | 1996 |
Mouse lung tumors exhibit specific Ki-ras mutations following transplacental exposure to 3-methylcholanthrene.
Topics: Animals; Base Sequence; Body Weight; Carcinogens; Crosses, Genetic; Cytochrome P-450 CYP1A1; Cytochr | 1996 |
Fetal mouse susceptibility to transplacental carcinogenesis: differential influence of Ah receptor phenotype on effects of 3-methylcholanthrene, 12-dimethylbenz[a]anthracene, and benzo[a]pyrene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Carcinogens; Crosses, Genetic; Female; Li | 1995 |
Isolated lung perfusion with melphalan for the treatment of metastatic pulmonary sarcoma.
Topics: Animals; Antineoplastic Agents, Alkylating; Infusions, Intravenous; Lung Neoplasms; Male; Melphalan; | 1996 |
A lymphocyte-activating monoclonal antibody induces regression of human tumors in severe combined immunodeficient mice.
Topics: Animals; Antibodies, Monoclonal; Carcinoma; Cell Line; Colonic Neoplasms; Female; Fibrosarcoma; Huma | 1997 |
Ki-ras mutations are an early event and correlate with tumor stage in transplacentally-induced murine lung tumors.
Topics: Animals; Blotting, Northern; Carcinogens; Cytochrome P-450 CYP1A1; Female; Genes, ras; Lung Neoplasm | 1997 |
Butylated hydroxytoluene exposure is necessary to induce lung tumors in BALB mice treated with 3-methylcholanthrene.
Topics: Animals; Butylated Hydroxytoluene; Female; Lung Neoplasms; Methylcholanthrene; Mice; Mice, Inbred BA | 1997 |
Environmental factors and aryl hydrocarbon hydroxylase activity (CYP1A1 phenotype) in human lymphocytes.
Topics: Adult; Aryl Hydrocarbon Hydroxylases; Carcinogens; Cells, Cultured; Cytochrome P-450 CYP1A1; Enzyme | 1997 |
Role of tumor suppressor genes in transplacental lung carcinogenesis.
Topics: Adenocarcinoma; Animals; Carcinogens; Cyclin-Dependent Kinase Inhibitor p16; Exons; Female; Genes, p | 1998 |
Demonstration of an interferon gamma-dependent tumor surveillance system in immunocompetent mice.
Topics: Adenocarcinoma; Animals; Graft Rejection; Humans; Immunocompetence; Interferon-gamma; Lung Neoplasms | 1998 |
Compensatory lung growth after partial pneumonectomy enhances lung tumorigenesis induced by 3-methylcholanthrene.
Topics: Animals; Butylated Hydroxytoluene; Dose-Response Relationship, Drug; Lung; Lung Neoplasms; Male; Met | 1999 |
Strain-dependent lung tumor formation in mice transplacentally exposed to 3-methylcholanthrene and post-natally exposed to butylated hydroxytoluene.
Topics: Animals; Base Sequence; Butylated Hydroxytoluene; DNA Primers; Female; Genes, Tumor Suppressor; Lung | 1999 |
3-Methylcholanthrene triggers the differentiation of alveolar tumor cells from canine bronchial basal cells and an altered p53 gene promotes their clonal expansion.
Topics: Animals; Bronchi; Carcinogens; Carcinoma, Bronchogenic; Cell Differentiation; Cell Transformation, N | 2000 |
Specific organ gene transfer in vivo by regional organ perfusion with herpes viral amplicon vectors: implications for local gene therapy.
Topics: Animals; beta-Galactosidase; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Humans; Lun | 2001 |
Induction of cytochromes P450 1A1 and 1B1 by emodin in human lung adenocarcinoma cell line CL5.
Topics: Adenocarcinoma; Anthracenes; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP1A1; Cytochrome P-45 | 2001 |
Alterations at the Ink4a locus in transplacentally induced murine lung tumors.
Topics: Animals; Base Sequence; Carcinogens; Cyclin-Dependent Kinase Inhibitor p16; DNA Methylation; Genes, | 2001 |
Manipulation of pulmonary prostacyclin synthase expression prevents murine lung cancer.
Topics: Animals; Antioxidants; Bronchoalveolar Lavage Fluid; Butylated Hydroxytoluene; Cytochrome P-450 Enzy | 2002 |
Quantitative trait loci that regulate susceptibility to both butylated hydroxytoluene-induced pulmonary inflammation and lung tumor promotion in CXB recombinant inbred mice.
Topics: Animals; Butylated Hydroxytoluene; Carcinogens; Chromosome Mapping; Genetic Predisposition to Diseas | 2002 |
[Dynamic study on expression of gelatinase A and its natural inhibitor during invasion and metastasis of induced lung cancer in Wistar rats].
Topics: Alkylating Agents; Animals; Carcinoma, Squamous Cell; Diethylnitrosamine; Female; Gene Expression Re | 2002 |
Development of tobacco smoke-induced lung tumors in mice fed Bowman-Birk protease inhibitor concentrate (BBIC).
Topics: Animals; Body Weight; Carcinogens; Lung Neoplasms; Male; Methylcholanthrene; Mice; Nicotiana; Time F | 2002 |
Aryl hydrocarbon hydroxylase and 16alpha-hydroxylase in cultured human lymphocytes.
Topics: Aryl Hydrocarbon Hydroxylases; Cells, Cultured; Colonic Neoplasms; Cytochrome P-450 CYP2C8; Cytochro | 1976 |
Effect of oil-attached BCG cell-wall skeleton and thymectomy on the incidence of lung cancer and amyloidosis induced by chemical carcinogens in rabbits.
Topics: 4-Nitroquinoline-1-oxide; Adenocarcinoma; Amyloidosis; Animals; BCG Vaccine; Carcinoma, Squamous Cel | 1978 |
Pulmonary tumor induction: three hydrocarbons compared.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Animals; Benz(a)Anthracenes; Benzopyrenes; Carcinogens; F | 1979 |
Electron microscopic observations on formation of pulmonary metastases.
Topics: Animals; Cell Nucleolus; Cell Nucleus; Cytoplasm; Endoplasmic Reticulum; Fibrosarcoma; Inclusion Bod | 1975 |
[Basic studies on lung cancer and their clinical significance (author's transl)].
Topics: Adenocarcinoma; Adult; Animals; Assisted Circulation; Asthma; Carcinoma, Small Cell; Cells, Cultured | 1975 |
Pulmonary metastases from autochthonous 3-methylcholanthrene-induced murine tumors.
Topics: Amputation, Surgical; Animals; Disease Models, Animal; Female; Hindlimb; Lung Neoplasms; Methylchola | 1979 |
Inhibition of host resistance by nutritional hypercholesteremia.
Topics: Animals; B-Lymphocytes; Cholesterol, Dietary; Cytotoxicity, Immunologic; Fibrosarcoma; Hypercholeste | 1979 |
Immune impairment and metastatic tumor growth: the need for an immunorestorative drug as an adjunct to surgery.
Topics: Animals; Antibodies, Neoplasm; Antibody Specificity; Cytotoxicity, Immunologic; Female; Fibrosarcoma | 1979 |
[Histologic studies of experimental lung cancer induced in dogs (author's transl)].
Topics: Adenocarcinoma; Animals; Carcinoma, Squamous Cell; Dogs; Female; Lung Neoplasms; Lymphatic Metastasi | 1979 |
Persistent binding of 3-methylcholanthrene to mouse lung DNA and its correlation with susceptibility to pulmonary neoplasia.
Topics: Animals; Chromatography, Gel; DNA; Lung Neoplasms; Methylcholanthrene; Mice; Mice, Inbred Strains; N | 1979 |
Antitumor activity of prumycin.
Topics: Aminoglycosides; Animals; Antibiotics, Antineoplastic; Female; Lethal Dose 50; Leukemia, Experimenta | 1979 |
Tumorigenic activity of 3-methylcholanthrene metabolites on mouse skin and in newborn mice.
Topics: Administration, Topical; Animals; Animals, Newborn; Carcinogens; Cocarcinogenesis; Drug Administrati | 1979 |
Lung tumors in mice suckled by 3-methylcholanthrene-treated mothers.
Topics: Adenocarcinoma; Adenoma; Animals; Animals, Suckling; Female; Lung Neoplasms; Male; Methylcholanthren | 1979 |
Vitamin A and the susceptibility of respiratory tract tissues to carcinogenic insult.
Topics: Animals; Carcinogens; Carcinoma, Squamous Cell; Drug Interactions; Female; Lung Neoplasms; Male; Met | 1979 |
Inducibility of microsomal enzymes in normal and pre-cancerous lung tissue. Synergistic action of 5-6 benzoflavon or methyl-cholanthrene in radiation induced carcinogenesis.
Topics: Animals; Benzoflavones; Carcinoma, Squamous Cell; Enzyme Induction; Lung; Lung Neoplasms; Male; Meth | 1979 |
Methylcholanthrene-induced metastatic mammary carcinoma in several inbred hamster strains.
Topics: Animals; Cricetinae; Cystadenoma; Female; Lung Neoplasms; Lymphatic Metastasis; Male; Mammary Neopla | 1979 |
Lung tumor response in mice to metals and metal salts.
Topics: Animals; Cocarcinogenesis; Injections, Intraperitoneal; Lead; Lung Neoplasms; Manganese Poisoning; M | 1977 |
[Early changes in transplants of lung organ cultures treated with several polycyclic hydrocarbons].
Topics: Adenoma; Animals; Benzopyrenes; Bronchial Diseases; Carcinoma; Cysts; Hyperplasia; Lung; Lung Neopla | 1976 |
Comparison of lung cancer and amyloidosis in rabbits induced by chemical carcinogens.
Topics: 4-Nitroquinoline-1-oxide; Amyloidosis; Animals; Bronchi; Carcinogens; Female; Liver Neoplasms; Lung | 1975 |
[The relationship between the activity of microsomal enzymes and pulmonary carcinogenesis in mice].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Animals; Antineoplastic Agents; Barbital; Chlorpromazine; | 1976 |
Biologic analysis of fetal MRC rat lung epithelial cells treated with 3-methylcholanthrene in culture: premalignant and malignant stages.
Topics: Animals; Animals, Newborn; Carcinoma, Squamous Cell; Cell Survival; Cell Transformation, Neoplastic; | 1977 |
Distribution of aryl hydrocarbon hydroxylase inducibility in cultured human lymphocytes.
Topics: Aryl Hydrocarbon Hydroxylases; Cells, Cultured; Enzyme Induction; Female; Humans; Lung Neoplasms; Ly | 1977 |
Immunosuppressive effects of 3-methylcholanthrene given intratracheally in various inbred strains of mice.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Female; Immunosuppressive Agents; Lung Neoplasms; Male; Meth | 1977 |
[Experimental lung neoplasms--carcinogenesis and immunology].
Topics: Adenocarcinoma; Animals; Carcinoma, Squamous Cell; Cricetinae; Lung Neoplasms; Methylcholanthrene; M | 1976 |
Effects of some low molecular weight sheep pineal fractions and melatonin on different tumors in rats and mice.
Topics: Animals; Female; Lung Neoplasms; Male; Melatonin; Methylcholanthrene; Mice; Molecular Weight; Neopla | 1976 |
Bacillus Calmette-Guérin contact immunotherapy of local and metastatic deposits of rat tumors.
Topics: Animals; BCG Vaccine; Female; Immunosuppression Therapy; Immunotherapy; Lung Neoplasms; Male; Methyl | 1976 |
Chromatographic separation of autofluorescent and quenching substances from the hydrocarbon in tissue.
Topics: Administration, Intranasal; Animals; Bile; Carcinogens; Chromatography; Ethanol; Feces; Female; Fluo | 1975 |
The carcinogenicity of polycyclic hydrocarbon epoxides in newborn mice.
Topics: Animals; Animals, Newborn; Benz(a)Anthracenes; Chrysenes; Ethers, Cyclic; Female; Liver Neoplasms; L | 1975 |
[Effect of ectopic transplantations on the cytological structure of mouse rhabdomyosarcomas].
Topics: Animals; Anterior Chamber; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Clone C | 1975 |
Levamisole treatment of local and metastatic growth of transplanted rat tumours.
Topics: Animals; Antigens, Neoplasm; Levamisole; Lung Neoplasms; Methylcholanthrene; Neoplasm Metastasis; Ne | 1975 |
Pituitary role in the growth of metastasizing MRMT-1 mammary carcinoma in rats.
Topics: Animals; Female; Hypophysectomy; Lung Neoplasms; Mammary Neoplasms, Experimental; Methylcholanthrene | 1976 |
Metastasis formation after intravenous tumour cell injection in thrombocytopenic rats.
Topics: Animals; Dextrans; Femoral Fractures; Fibrosarcoma; Lung Neoplasms; Methylcholanthrene; Neoplasm Met | 1976 |
The influence of vitamin A on the susceptibility of the rat lung to 3-methylcholanthrene.
Topics: Animals; Female; Lung; Lung Neoplasms; Methylcholanthrene; Neoplasms, Experimental; Rats; Tretinoin; | 1976 |
Evaluation of beeswax-tricaprylin vehicle for pulmonary carcinogenesis studies.
Topics: Animals; Caprylates; Drug Implants; Lung; Lung Neoplasms; Methylcholanthrene; Nicotine; Pharmaceutic | 1976 |
Protection by methylcholanthrene against hepatic carcinogenesis in rats ingesting N-4-(4'-fluorobiphenyl) acetamide.
Topics: Aminobiphenyl Compounds; Animals; Carcinogens; Carcinoma; Kidney Neoplasms; Liver Neoplasms; Lung Ne | 1976 |
Hydrocarbon-nitrosamine synergism as a possible amplifying factor in lung tumorigenesis by tobacco smoke.
Topics: Animals; Benzopyrenes; Dimethylnitrosamine; Drug Synergism; Epoxide Hydrolases; Lung Neoplasms; Meth | 1976 |
Fibrosarcoma cells transduced with the IL-6 gene exhibited reduced tumorigenicity, increased immunogenicity, and decreased metastatic potential.
Topics: Animals; Female; Fibrosarcoma; Graft Rejection; Histocompatibility Antigens Class I; Immunocompromis | 1992 |
Malignant progression of a mouse fibrosarcoma by host cells reactive to a foreign body (gelatin sponge).
Topics: Animals; Dinoprostone; Female; Fibrosarcoma; Foreign-Body Reaction; Lung Neoplasms; Methylcholanthre | 1992 |
Antitumor activity of two novel low immunosuppressive fluoropyrimidines UK-21 and UK-25.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Body Weight; Fluorouracil; Glycine; Leukemia L | 1992 |
Bronchial and pulmonary carcinogenesis at focal sites in dogs and hamsters.
Topics: Animals; Benzo(a)pyrene; Bronchial Neoplasms; Bronchoscopy; Carcinogens; Cricetinae; Disease Models, | 1992 |
[Precancerous and cancerous lesions and their gamma-glutamyl transpeptidase expression in 3-methylcholanthrene-induced lung carcinogenesis in rats].
Topics: Adenoma; Animals; Biomarkers, Tumor; Carcinoma, Squamous Cell; gamma-Glutamyltransferase; Lung Neopl | 1991 |
Strain A/J mouse lung adenoma growth patterns vary when induced by different carcinogens.
Topics: 1,2-Dimethylhydrazine; Adenoma; Aflatoxins; Animals; Benzo(a)pyrene; Carcinogens; Cell Transformatio | 1991 |
Enhanced antitumor reactivity of tumor-sensitized T cells by interferon alfa.
Topics: Animals; Antigens, Neoplasm; Cells, Cultured; Cytotoxicity, Immunologic; Female; Fibrosarcoma; Histo | 1991 |
Variable regression of experimental bronchial preneoplasia during carcinogenesis.
Topics: Animals; Bronchi; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Disease Models, Animal; Dogs; L | 1991 |
[Inhibitory effect of micronutrients and BHA on lung cancer induced in rats].
Topics: Animals; Butylated Hydroxyanisole; Carcinoma, Squamous Cell; Cysteine; Food, Fortified; Lung Neoplas | 1990 |
A weakly tumorigenic phenotype with high MHC class-I expression is associated with high metastatic potential after surgical removal of the primary murine fibrosarcoma.
Topics: Animals; Clone Cells; Fibrosarcoma; H-2 Antigens; Histocompatibility Antigens Class I; Interferon-ga | 1990 |
Enhanced lung colonization and tumorigenicity of fused cells isolated from primary MCA tumors.
Topics: Animals; Cell Fusion; Clone Cells; Glucose-6-Phosphate Isomerase; Lung Neoplasms; Methylcholanthrene | 1990 |
In vivo antitumor activity of ilmofosine.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophos | 1990 |
Effect of blood transfusions on experimental pulmonary metastases in mice.
Topics: Animals; Cell Count; Fibrosarcoma; Lung Neoplasms; Male; Methylcholanthrene; Mice; Mice, Inbred C57B | 1990 |
The formation of 3-methylcholanthrene-initiated lung tumors correlates with induction of cytochrome P450IA1 by the carcinogen in fetal but not adult mice.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Carcinogenicity Tests; Cytochrome P-450 Enzyme System; Enzym | 1990 |
[Subcutaneous injection of spleen cells from mice bearing large methylcholanthrene-induced sarcoma enhances subcutaneous tumors and artificial pulmonary metastases].
Topics: Animals; Epitopes; Immune Tolerance; Injections, Subcutaneous; Lung Neoplasms; Male; Methylcholanthr | 1987 |
Modification of transplacental tumorigenesis by 3-methylcholanthrene in mice by genotype at the Ah locus and pretreatment with beta-naphthoflavone.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Female; Fetal Diseases; Fetus; Flavonoids; Genotype; Li | 1989 |
Modulation of lung tumor development in mice with the soybean-derived Bowman-Birk protease inhibitor.
Topics: Animals; Lung Neoplasms; Male; Methylcholanthrene; Mice; Mice, Inbred A; Trypsin Inhibitor, Bowman-B | 1989 |
[Possibilities of objective evaluation of local reactive cell infiltrates in transplantable tumors].
Topics: Animals; Cell Count; Leukocyte Count; Lung Neoplasms; Macrophages; Methylcholanthrene; Mice; Neoplas | 1989 |
Anticachectin/tumor necrosis factor-alpha antibodies attenuate development of cachexia in tumor models.
Topics: Adenocarcinoma; Animals; Cachexia; Female; Hematocrit; Immunization, Passive; Lung Neoplasms; Methyl | 1989 |
[Blood coagulation and metastasis].
Topics: Animals; Fibrosarcoma; Humans; Lung Neoplasms; Membrane Proteins; Methylcholanthrene; Mice; Neoplasm | 1989 |
[Changes in primary heat sensitivity of rhabdomyosarcoma PA-2 cells in rats during selection for heat resistance].
Topics: Animals; Hot Temperature; Lung Neoplasms; Methylcholanthrene; Rats; Rhabdomyosarcoma; Selection, Gen | 1989 |
[Ultrastructural and histogenetic studies on experimental pulmonary carcinoma].
Topics: Adenocarcinoma; Adenocarcinoma, Bronchiolo-Alveolar; Animals; Benzo(a)pyrene; Carcinoma, Squamous Ce | 1987 |
Non-small cell lung cancer in autogenous subcutaneous bronchial grafts in dogs.
Topics: Animals; Bronchi; Carcinoma, Non-Small-Cell Lung; DNA, Neoplasm; Dogs; Drug Implants; Lung Neoplasms | 1988 |
Effects of a combination of cyclophosphamide and human recombinant interleukin 2 on pulmonary metastasis after the surgical removal of a 3-methylcholanthrene-induced primary tumor in autochthonous mice.
Topics: Animals; Combined Modality Therapy; Cyclophosphamide; Female; Interleukin-2; Killer Cells, Natural; | 1988 |
Antigen-specific therapy of experimental metastases.
Topics: Animals; Antigens, Neoplasm; Cell Line; Cyclophosphamide; Female; Histocompatibility Antigens; Lung | 1985 |
Proliferation kinetics of a murine fibrosarcoma during fractionated irradiation.
Topics: Animals; Cell Division; Clone Cells; Fibrosarcoma; Kinetics; Lung Neoplasms; Male; Methylcholanthren | 1988 |
Induction of squamous cell carcinoma in the rat lung by 1,6-dinitropyrene.
Topics: Animals; Carcinogens; Carcinoma, Squamous Cell; Kidney Neoplasms; Lung Neoplasms; Male; Methylcholan | 1986 |
Antitumor efficacy of lymphokine-activated killer cells and recombinant interleukin 2 in vivo: successful immunotherapy of established pulmonary metastases from weakly immunogenic and nonimmunogenic murine tumors of three district histological types.
Topics: Animals; Cytotoxicity, Immunologic; Dose-Response Relationship, Drug; Immunotherapy; Interleukin-2; | 1986 |
Immunotherapy of pulmonary metastases using monoclonal antibody to T-cell suppressor factor and interleukin 2.
Topics: Animals; Antibodies, Monoclonal; Cytotoxicity Tests, Immunologic; Dose-Response Relationship, Immuno | 1987 |
Separation of early diffuse alveolar cell proliferation from enhanced tumor development in mouse lung.
Topics: Animals; Butylated Hydroxytoluene; Cell Division; Hyperplasia; Lung Neoplasms; Male; Methylcholanthr | 1986 |
Establishment and characterization of high- and low-metastatic clones derived from a methylcholanthrene-induced rat fibrosarcoma.
Topics: Animals; Cell Line; Fibrosarcoma; Growth Substances; Karyotyping; Lung Neoplasms; Macrophages; Methy | 1986 |
Modification of lung tumor growth by hyperoxia.
Topics: Animals; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Cell Division; DNA; Dose-Response Relat | 1986 |
Effect of tuftsin on in vivo development of 3-methylcholanthrene-induced primary fibrosarcoma and Lewis lung carcinoma in mice.
Topics: Animals; Carcinoma; Cell Line; Fibrosarcoma; Lung Neoplasms; Methylcholanthrene; Mice; Mice, Inbred | 1985 |
[Experimental lung cancer induced by chemical carcinogens and immunity].
Topics: 4-Nitroquinoline-1-oxide; Adjuvants, Immunologic; Animals; Benzo(a)pyrene; Female; Immunotherapy; Lu | 1985 |
Characterization of spontaneous metastases from autochthonous 3-methylcholanthrene-induced tumors.
Topics: Animals; Cell Line; Kidney Neoplasms; Lung Neoplasms; Methylcholanthrene; Mice; Mice, Inbred C3H; Mi | 1986 |
Fetal mouse susceptibility to transplacental lung and liver carcinogenesis by 3-methylcholanthrene: positive correlation with responsiveness to inducers of aromatic hydrocarbon metabolism.
Topics: Animals; Biotransformation; Female; Fetus; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Mate | 1985 |
Enhancing effect of quercetin on 3-methylcholanthrene carcinogenesis in C57Bl/6 mice.
Topics: Animals; Bone Marrow Cells; Cocarcinogenesis; Female; Flavonoids; Lung Neoplasms; Methylcholanthrene | 1985 |
Cell kinetics in mouse lung following administration of carcinogens and butylated hydroxytoluene.
Topics: Animals; Autoradiography; Butylated Hydroxytoluene; DNA; Drug Synergism; Hyperplasia; Injections, In | 1985 |
Aryl hydrocarbon hydroxylase inducibility and bronchogenic carcinoma.
Topics: Adenocarcinoma; Adult; Aged; Benz(a)Anthracenes; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Car | 1973 |
Biological tests of carcinogenic activity.
Topics: Animals; Azo Compounds; Biological Assay; Carcinogens; Carcinoma, Hepatocellular; Carcinoma, Papilla | 1968 |
The syncarcinogenic effect of methylcholanthrene and dimethylnitrosamine in Swiss mice.
Topics: Adenocarcinoma; Adenoma; Animals; Carcinogens; Carcinoma; Drug Synergism; Female; Kidney Neoplasms; | 1973 |
Biological behavior through successive transplant generations of transplantable tumors derived originally from primary chemically induced and spontaneous sources in mice.
Topics: Animals; Ethiodized Oil; Iodized Oil; Lung Neoplasms; Methylcholanthrene; Mice; Neoplasm Metastasis; | 1968 |
Relationship of injury to chemical carcinogenesis in the lungs of rats.
Topics: Animals; Fibrosarcoma; Hydrocarbons, Halogenated; Injections, Intravenous; Lung Neoplasms; Male; Met | 1968 |
Environmental carcinogens.
Topics: Aflatoxins; Air Pollution; Animals; Arsenic; Azo Compounds; Carcinogens; Coal Tar; Environmental Exp | 1968 |
Sensitivity of newborn mice to carcinogenic agents.
Topics: Adenocarcinoma; Adenoma; Animals; Animals, Newborn; Benz(a)Anthracenes; Carcinogens; Carcinoma, Hepa | 1968 |
[Experimental hematogenous metastasis of a fibrosarcoma in animals with and without spleen].
Topics: Animals; Antibody Formation; Carcinoma, Hepatocellular; Fibrosarcoma; Liver Neoplasms; Lung Neoplasm | 1969 |
Fine structure of nuclear inclusions in murine pulmonary tumor cells.
Topics: Adenocarcinoma; Adenoma; Animals; Cytoplasmic Granules; Inclusion Bodies; Lung Neoplasms; Methylchol | 1970 |
[A new animal for experimental oncologic research--the Dzhungarian hamster].
Topics: Animals; Animals, Laboratory; Benz(a)Anthracenes; Carcinoma, Hepatocellular; Carcinoma, Squamous Cel | 1970 |
Experimental studies on trauma and metastasis formation.
Topics: Animals; Blood Coagulation; Carcinoma, Hepatocellular; Dextrans; Female; Fibrinolysis; Heparin; Inje | 1968 |
[Methylcholanthrene sensitivity of epithelial tissues of the respiratory tract in BALB-c-Cb-Se mice].
Topics: Adenocarcinoma, Bronchiolo-Alveolar; Adenoma; Animals; Bronchial Neoplasms; Epithelium; Lung Neoplas | 1971 |
Chemical carcinogenesis in Syrian hamsters.
Topics: Adenocarcinoma, Bronchiolo-Alveolar; Animals; Azo Compounds; Benz(a)Anthracenes; Benzopyrenes; Bronc | 1972 |
Chemical carcinogenesis in mice inhibited by interferon.
Topics: Adenoma; Animals; Antigens, Viral; Cell Transformation, Neoplastic; Female; Fibrosarcoma; Interferon | 1972 |
Intracisternal A-type and C-type particles observed in pulmonary tumors in mice.
Topics: Adenocarcinoma; Animals; Antigens, Viral; Ascites; Carcinoma, Hepatocellular; Culture Techniques; Fl | 1972 |
Electron-microscope observations on the formation of the cytoplasmic lamellar inclusion bodies in murine pulmonary tumours induced in vitro.
Topics: Adenocarcinoma; Adenoma; Animals; Cytoplasm; Glycogen; Golgi Apparatus; Inclusion Bodies; Lung Neopl | 1972 |
Possible activation of C-type particles during 'progression' of the chemically-induced pulmonary tumors in mice.
Topics: Animals; Ascitic Fluid; Cells, Cultured; Lung Neoplasms; Methylcholanthrene; Mice; Microscopy, Elect | 1973 |
Neoplasms and amyloidosis in strains of mice treated with 3-methylcholanthrene.
Topics: Adenoma; Amyloidosis; Animals; Carcinoma, Hepatocellular; Carcinoma, Squamous Cell; Female; Liver Ne | 1974 |
Suppression of chemically induced pulmonary tumors by treatment of strain A mice with murine sarcoma virus.
Topics: Adenoma; Animals; Female; Gammaretrovirus; Lung Neoplasms; Male; Methylcholanthrene; Mice; Mice, Inb | 1974 |
A preliminary investigation into the role of immunity in modifying the blood- borne spread of chemically induced rat sarcomas.
Topics: Animals; Benzopyrenes; Carcinogens; Carcinoma, Hepatocellular; Ethionine; Graft Rejection; Immunizat | 1974 |
Carcinogenic polynuclear hydrocarbons bind to macromolecules in cultured human bronchi.
Topics: Autoradiography; Benz(a)Anthracenes; Benzopyrenes; Bronchi; Carcinogens; Cell Nucleus; Cells, Cultur | 1974 |
Measurement of epidermoid carcinoma development induced in the lungs of rats by 3-methylcholanthrene-containing beeswax pellets.
Topics: Animals; Bees; Carcinogens; Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; Female; Lung | 1974 |
Immunoprophylaxis and immunotherapy for a murine fibrosarcoma with C. granulosum and C. parvum.
Topics: Animals; Cell Transformation, Neoplastic; Corynebacterium; Female; Fibrosarcoma; Immunization; Liver | 1974 |
Tumor development after 3-methylcholanthrene in immunologically deficient athymic-nude mice.
Topics: Adenoma; Animals; Female; Fibrosarcoma; Graft Rejection; Immunologic Deficiency Syndromes; Lung Neop | 1974 |
BCG immunotherapy of rat tumors of defined immunogenicity.
Topics: Adjuvants, Immunologic; Animals; Antigens, Neoplasm; BCG Vaccine; Cell Count; Immunity; Immunosuppre | 1973 |
[Epigenetic variability in cell populations of mouse rhabdomyosarcoma].
Topics: Animals; Clone Cells; Genetic Variation; Lung; Lung Neoplasms; Methylcholanthrene; Mice; Mice, Inbre | 1972 |
[Analysis of clone formation in vivo using "epigenetic markers"].
Topics: Animals; Clone Cells; Lung; Lung Neoplasms; Methylcholanthrene; Mice; Mice, Inbred Strains; Neoplasm | 1972 |
Induction of tumors by direct injection of carcinogen into mouse fetus.
Topics: Animals; Carcinogens; Female; Fetus; Injections; Lung Neoplasms; Methylcholanthrene; Mice; Neoplasms | 1972 |
BCG immunotherapy of pulmonary growths from intravenously transferred rat tumour cells.
Topics: Adjuvants, Immunologic; Animals; BCG Vaccine; Immunotherapy; Injections, Intravenous; Lung Neoplasms | 1973 |
A factor preventing the development of lung metastases in rats with sarcomas.
Topics: Animals; Antibody Formation; Immune Sera; Immunity, Maternally-Acquired; Immunization, Passive; Leg; | 1973 |
Effect of excision or local radiotherapy to a tumor and its regional nodes on metastases.
Topics: Amputation, Surgical; Animals; Female; Fibrosarcoma; Lung Neoplasms; Mammary Neoplasms, Experimental | 1973 |
Effects of vitamin A on 3-methylcholanthrene-induced squamous metaplasias and early tumors in the respiratory tract of rats.
Topics: Animals; Carcinoma, Squamous Cell; Hyperplasia; Injections; Intubation, Gastrointestinal; Liver; Lun | 1973 |
The metastatic potential of experimental pulmonary metastases.
Topics: Animals; Female; Immune Sera; Lung Neoplasms; Methods; Methylcholanthrene; Mice; Mice, Inbred C57BL; | 1973 |
Nuclear magnetic resonance studies of several experimental and human malignant tumors.
Topics: Adenocarcinoma; Animals; Carcinoma, Squamous Cell; Colonic Neoplasms; Fibrosarcoma; Humans; Kidney N | 1973 |
The effect of splenectomy on fibrosarcoma "metastases" in lungs of mice.
Topics: Animals; Fibrosarcoma; Immunity, Active; Lung Neoplasms; Lymphocytes; Male; Methylcholanthrene; Mice | 1973 |
Immunological resistance to pulmonary metastases in C3Hf-Bu mice bearing syngeneic fibrosarcoma of different sizes.
Topics: Animals; Antigen-Antibody Complex; Fibrosarcoma; Immunity, Cellular; Immunization; Immunization, Pas | 1974 |
Frequency and organ distribution of lung tumor metastases in CF-1 mice.
Topics: Animals; Carcinoma; Female; Heart Neoplasms; Kidney; Kidney Neoplasms; Liver; Liver Neoplasms; Lung | 1974 |
Separation of cells from a fibrosarcoma in renografin density gradients.
Topics: Amino Sugars; Animals; Cell Count; Cell Division; Cell Separation; Centrifugation, Density Gradient; | 1974 |
In vitro demonstration of altered antigenicity of metastases from a primary methylcholanthrene-induced sarcoma.
Topics: Animals; Antigens, Neoplasm; Fibrosarcoma; In Vitro Techniques; Lung Neoplasms; Lymphocytes; Methylc | 1974 |
Development of tumour in transplanted lungs of newborn and adult mice.
Topics: Animals; Animals, Newborn; Female; Lung Neoplasms; Lung Transplantation; Male; Methylcholanthrene; M | 1970 |
Influence of Candida albicans glycoprotein on 3-methylcholanthrene induced malignancy in newborn rodents.
Topics: Animals; Animals, Newborn; Candida; Carcinogens; Female; Fibrosarcoma; Glycoproteins; Histological T | 1971 |
Study of the potential carcinogenicity of topical drug. Suggestions for a new experimental approach.
Topics: Adenocarcinoma; Administration, Topical; Animals; Anti-Inflammatory Agents; Bronchial Neoplasms; Car | 1971 |
Effect of barbital on carcinogenic action and metabolism of 4-dimethylaminoazobenzene.
Topics: Aminobenzoates; Animals; Barbiturates; Bile; Glucuronates; Liver; Liver Neoplasms; Lung Neoplasms; M | 1967 |
The effects of two isomeric benzoflavones on aryl hydrocarbon hydroxylase and the toxicity and carcinogenicity of polycyclic hydrocarbons.
Topics: Adenoma; Adrenal Gland Diseases; Animals; Benz(a)Anthracenes; Benzopyrenes; Benzyl Compounds; Cells, | 1972 |
Experimental cancer of the lung in rabbits induced by chemical carcinogens.
Topics: Adenocarcinoma; Animals; Autopsy; Bronchoscopy; Carcinogens; Carcinoma; Carcinoma, Squamous Cell; Cy | 1972 |
Altered antigenicity in spontaneous pulmonary metastases from an antigenic murine sarcoma.
Topics: Animals; Antigens; Antigens, Neoplasm; Body Weight; Lung Neoplasms; Methylcholanthrene; Mice; Neopla | 1972 |
Carcinogenesis in pulmonary epithelia in mice on different levels of vitamin A.
Topics: Adenocarcinoma; Animals; Body Weight; Carcinoma, Squamous Cell; Lung Neoplasms; Male; Metaplasia; Me | 1972 |
Effect of tumor immunity on production of lung tumors after intravenous inoculation of antigenically identical tumor cells.
Topics: Animals; Antigens, Neoplasm; Hindlimb; Injections, Intravenous; Lung Neoplasms; Methylcholanthrene; | 1972 |
[Experimental pulmonary cancer].
Topics: Adenocarcinoma; Animals; Carcinoma, Squamous Cell; Cricetinae; Lung Neoplasms; Methylcholanthrene; M | 1972 |
Immunotherapy combined with primary resection of murine fibrosarcoma: correlation of immunological status of the host with prevention of metastases.
Topics: Amputation, Surgical; Animals; Antibodies, Neoplasm; Antigen-Antibody Complex; Antigen-Antibody Reac | 1972 |
Studies on the effect of methoxy-substituted glycerol ethers on tumour growth and metastasis formation.
Topics: Administration, Oral; Animals; Body Weight; Ethers; Female; Glycerol; Injections, Intraperitoneal; I | 1971 |
The fate of circulating methylcholanthrene tumor cells in mice with tumor-specific immunity.
Topics: Amputation, Surgical; Animals; Culture Techniques; Disease Models, Animal; Female; Hindlimb; Immunit | 1971 |
Methylcholanthrene-induced endometrial carcinoma in mice and rats: a histological and ultrastructural study.
Topics: Adenocarcinoma; Animals; Carcinoma, Squamous Cell; Carcinosarcoma; Cell Nucleus; Cytoplasm; Endometr | 1971 |
Progression of pulmonary tumor in mice. 1. Histological studies of primary and transplanted pulmonary tumors.
Topics: Adenocarcinoma; Age Factors; Animals; Carcinoma; Injections, Intraperitoneal; Injections, Subcutaneo | 1971 |
Autoradiographic study on localization of fibrinogen in rabbit lung cancer.
Topics: Adenocarcinoma; Animals; Autoradiography; Carcinogens; Carcinoma, Squamous Cell; Fibrinogen; Iodine | 1971 |
Transplacental carcinogenic effect of 3-methylcholanthrene in mice and its quantitation in fetal tissues.
Topics: Animals; Animals, Newborn; Carbon Isotopes; Chromatography, Thin Layer; Female; Fetus; Liver; Lung; | 1971 |
The effect of bilateral adrenalectomy and ovariectomy on the induction of carcinoma of the mouse uterine cervix.
Topics: Adrenal Glands; Adrenalectomy; Animals; Carcinoma, Squamous Cell; Castration; Cell Transformation, N | 1969 |
Experimental tumour metastases and blood coagulability.
Topics: Aminocaproates; Animals; Blood Coagulation; Coumarins; Female; Heparin; Lung Neoplasms; Male; Melano | 1970 |
[Morphologic behavior of a fibrosarcoma following transplantation into various organs].
Topics: Animals; Cell Transformation, Neoplastic; Female; Fibrosarcoma; Glioma; Kidney Neoplasms; Liver Neop | 1970 |
Methylcholanthrene-induced neoplasms in germ-free RFM mice.
Topics: Administration, Oral; Animals; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Croton Oil | 1971 |
[Experimental bronchial precancerosis and carcinoma of the rat lung].
Topics: Animals; Bronchial Neoplasms; Carcinoma; Lung Neoplasms; Metaplasia; Methylcholanthrene; Neoplasms, | 1967 |
Effect of heparin, coumarin and -aminocaproic acid (EACA) on spontaneous metastasis formation. Influence on the moment of metastasis formation. Possible cytotoxic effect of heparin and coumarin in blood.
Topics: Aminocaproates; Animals; Coumarins; Heparin; Lung Neoplasms; Lymphatic Metastasis; Methylcholanthren | 1969 |
Pulmonary tumour induction in vitro: genetic influence.
Topics: Animals; Culture Techniques; Cytogenetics; Genes, Dominant; Lung Neoplasms; Methylcholanthrene; Mice | 1970 |
[The effect of iron-dextran and ironfree colloid on the distribution of experimental metastases].
Topics: Animals; Antineoplastic Agents; Iron-Dextran Complex; Liver Neoplasms; Lung Neoplasms; Methylcholant | 1970 |
Pulmonary adenomata induced by carcinogen treatment in organ culture. Influence of increasing amounts of carcinogen.
Topics: Adenoma; Animals; Culture Techniques; Female; Lung Neoplasms; Male; Methylcholanthrene; Mice; Neopla | 1970 |
Fine structure of murine pulmonary adenocarcinomata induced by treatment with 20-methylcholanthrene in organ culture.
Topics: Adenocarcinoma; Animals; Cell Membrane; Cytoplasmic Granules; Lung Neoplasms; Methylcholanthrene; Mi | 1970 |
Experimental models in environmental carcinogenesis.
Topics: Air Pollution; Animals; Benzopyrenes; Bronchi; Carcinogens; Carcinoma, Bronchogenic; Carcinoma, Squa | 1971 |
Antigenic specificities on murine sarcoma cells. Reciprocal relationship between normal transplantation antigens (H-2) and tumor-specific immunogenicity.
Topics: Animals; Antigen-Antibody Reactions; Chromium Isotopes; Cytotoxicity Tests, Immunologic; Female; His | 1971 |
Controlling factors in urethan carcinogenesis in mice: effect of enzyme inducers and metabolic inhibitors.
Topics: Animals; Body Weight; Chlordan; Cycloheximide; Dactinomycin; Flavonoids; Hematocrit; Lung Neoplasms; | 1971 |
Effect of immune status on the development of artificially induced metastases in different anatomical locations.
Topics: Animals; Immune Tolerance; Injections, Intraperitoneal; Injections, Subcutaneous; Liver Neoplasms; L | 1971 |
Experimental induction of lung cancer in rat and mouse with 20-methylcholanthrene in Freund's adjuvant.
Topics: Adenocarcinoma; Adenoma; Animals; Carcinoma, Squamous Cell; Female; Fluorometry; Freund's Adjuvant; | 1967 |
Combined carcinogenic effects of dimethylnitrosamine and 3-methylcholanthrene in the rat.
Topics: Animals; Drug Synergism; Liver Neoplasms; Lung Neoplasms; Methylcholanthrene; Neoplasms, Experimenta | 1968 |
The causes of lung cancer.
Topics: Aerosols; Air Pollution; Animals; Carcinogens; Carcinoma, Squamous Cell; Cricetinae; In Vitro Techni | 1968 |
Warfarin treatment of mice bearing autochthonous tumors: effect on spontaneous metastases.
Topics: Animals; Female; Lung Neoplasms; Methylcholanthrene; Mice; Neoplasm Metastasis; Neoplasm Transplanta | 1968 |
Effect of heparin, epsilon-aminocaproic acid and protamine on spontaneous metastasis formation from resectable tail-tumours.
Topics: Aminocaproates; Animals; Anticoagulants; Antifibrinolytic Agents; Heparin; Lung Neoplasms; Methylcho | 1968 |
Effect of heparin, epsilon-aminocaproic acid and coumarin on tumour growth and spontaneous metastasis formation.
Topics: Aminocaproates; Animals; Anticoagulants; Antifibrinolytic Agents; Coumarins; Heparin; Lung Neoplasms | 1968 |
Pulmonary adenomata induced by carcinogen treatment in organ culture. Influence of duration of treatment.
Topics: Adenoma; Animals; Carcinoma; Culture Techniques; Lung Neoplasms; Methylcholanthrene; Mice; Neoplasm | 1968 |
Experimental lung cancer in rabbits induced by chemical carcinogens.
Topics: Adenocarcinoma; Animals; Bronchi; Carcinogens; Carcinoma, Squamous Cell; Diaphragm; Female; Injectio | 1968 |
[Pulmonary metastasization and allotransplantability (murine sarcoma caused by methylcholanthrene)].
Topics: Animals; Lung Neoplasms; Methylcholanthrene; Mice; Neoplasm Metastasis; Neoplasm Transplantation; Sa | 1968 |
Relation of thymidine index to pulmonary tumor response in mice receiving urethan and other carcinogens.
Topics: Animals; Autoradiography; Carbamates; Carcinogens; Cytarabine; Dactinomycin; DNA; Fluorouracil; Inje | 1969 |
[Alkaline phosphatase activity in lung tissues of XVII-G and C57BL mice].
Topics: Age Factors; Alkaline Phosphatase; Animals; Benz(a)Anthracenes; Bile Ducts; Female; Fluorenes; Histo | 1969 |
Fine structure of murine pulmonary adenomata induced by carcinogen treatment in organ culture.
Topics: Adenoma; Animals; Lung Neoplasms; Methylcholanthrene; Mice; Microscopy, Electron | 1969 |
Metastasis of experimentally induced skin tumors.
Topics: Animals; Carcinoma, Squamous Cell; Lung Neoplasms; Lymphatic Metastasis; Methylcholanthrene; Mice; N | 1965 |
Induction of tumors in mice given a minute single dose of dibenz[a,h]anthracene or 3-methylcholanthrene as newborns. A dose-response study.
Topics: Animals; Animals, Newborn; Benz(a)Anthracenes; Fibrosarcoma; Injections, Subcutaneous; Lung Neoplasm | 1965 |
Pulmonary adenomata induced by carcinogen treatment in organ culture.
Topics: Adenoma; Animals; Culture Techniques; Lung; Lung Neoplasms; Methylcholanthrene; Mice | 1966 |
A spontaneously metastasizing 20-methylcholanthrene-induced rhabdomyosarcoma and its transformation to ascites form in the CBA mouse.
Topics: Animals; Carcinogens; Chromosome Aberrations; Chromosome Disorders; Female; Injections, Intraperiton | 1966 |
Effect of heparin and plasminogen inhibitor (EACA) in brief and prolonged treatment on intravenously injected tumour cells.
Topics: Aminocaproates; Animals; Heparin; Liver Neoplasms; Lung Neoplasms; Methylcholanthrene; Mice; Neoplas | 1966 |