3-methylcholanthrene has been researched along with Liver Neoplasms in 148 studies
Methylcholanthrene: A carcinogen that is often used in experimental cancer studies.
3-methylcholanthrene : A pentacyclic ortho- and peri-fused polycyclic arene consisting of a dihydrocyclopenta[ij]tetraphene ring system with a methyl substituent at the 3-position.
Liver Neoplasms: Tumors or cancer of the LIVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The animal models were Sewall Wright strain 13 guinea pigs with 3-methyl-cholanthrene (MCA)-induced fibrosarcomas and strain 2 guinea pigs with diethylnitrosamine (DEN)-induced hepatocarcinomas." | 3.66 | Guinea pig cell-mediated tumor immunity: the chromium release assay detects both cytolysis and serum blocking for syngeneic chemically-induced tumors. ( Blazkovec, AA; Miller, FR, 1979) |
| "The characteristic clostridial growth which is testable, after systemic administration of tetanus spores, as a positive tumour tetanus - correlation, was manifested by a highly selective tetanus lethality of rats with progressive hepatomas following induction with dimethylaminoazobenzene and diethylnitrosamine, respectively, as well as with methylcholanthren-induced fibrosarcomas of the rat." | 3.65 | [The tumor-tetanus assay--experimental studies on the biological differentiation between carcinogenesis and organ regeneration of the rat (author's transl)]. ( Fabricius, EA; Schneeweiss, U, 1975) |
| "We propose a novel mechanism for aneuploidy generation that involves impaired telomere replication upon loss of cohesin-SA1, with clear implications in tumourigenesis." | 1.38 | Cohesin-SA1 deficiency drives aneuploidy and tumourigenesis in mice due to impaired replication of telomeres. ( Blasco, MA; Cañamero, M; Carretero, M; Cuadrado, A; Drosopoulos, WC; Losada, A; Martínez, P; Remeseiro, S; Schildkraut, CL, 2012) |
| "As a subject of inquiry the hepatoma cell cultures HepG2 expressed Ah receptor and G27 not expressed Ah receptor were used." | 1.37 | [Activation of transcription factor NF-kappaB by carcinogenic polycyclic aromatic hydricarbons]. ( Kobliakov, VA; Volkov, MS, 2011) |
| " Further study demonstrated that UGT1A1 mRNA expression could be induced in human hepatocyte cultures by either increasing the chrysin dosing frequency or by modulating chrysin metabolism, suggesting that the differential induction observed in hepatocytes and HepG2 cells was due to differences in the metabolic clearance of chrysin." | 1.33 | Differential UGT1A1 induction by chrysin in primary human hepatocytes and HepG2 Cells. ( Graham, RA; Krol, WL; Lecluyse, EL; Negishi, M; Silver, IS; Smith, CM; Wang, H, 2005) |
| " Dose-response studies revealed that the concentration of 3MC required to half-maximally activate transcription (EC(50)) was >100-fold higher for an ER reporter (27-57 muM) than for an AhR reporter (86-250 nM) in both MCF-7 cells and in human endometrial cancer Ishikawa cells." | 1.33 | Aryl hydrocarbon receptor-independent activation of estrogen receptor-dependent transcription by 3-methylcholanthrene. ( Shipley, JM; Waxman, DJ, 2006) |
| "When murine hepatoma cell line Hepa-1c1c7 was stably transfected with this construct, established sensor clones secreted SEAP following stimulation with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)." | 1.32 | DRESSA: biosensing of dioxin and dioxin-like chemicals using secreted alkaline phosphatase. ( Hiramatsu, N; Kasai, A; Kitamura, M; Maeda, S; Meng, Y; Takeda, M; Yao, J, 2004) |
| " The expression of ALDH3A1 in HepG2 cells showed typical time- and dose-response curves of induction after application of 3MC (1-5 days, 1." | 1.31 | Effects of 3-methylcholanthrene and aspirin co-administration on ALDH3A1 in HepG2 cells. ( Marselos, M; Pappas, P; Sotiropoulou, M, 2001) |
| " In an effort better to understand factors that may affect the oral bioavailability of the bioflavonoids from dietary sources, the metabolism of chrysin by cultured intestinal Caco-2 cells and hepatic Hep G2 cells was studied, together modelling human presystemic metabolism." | 1.30 | Extensive metabolism of the flavonoid chrysin by human Caco-2 and Hep G2 cells. ( Galijatovic, A; Otake, Y; Walle, T; Walle, UK, 1999) |
| "(3) A human hepatoma cell line (Hep G2) was studied to obtain information on the inducibility of human UDP-GT activities by 3-methylcholanthrene-type inducers." | 1.27 | Differential induction of human liver UDP-glucuronosyltransferase activities by phenobarbital-type inducers. ( Bock, KW; Bock-Hennig, BS, 1987) |
| "It is concluded, that HepG2 hepatoma cells behave similar to the normal hepatocytes in terms of ALDH regulation and can be used for studies on the activity of ALDH as modified by added xenobiotics." | 1.27 | Effect of phenobarbital and 3-methylcholanthrene on aldehyde dehydrogenase activity in cultures of HepG2 cells and normal human hepatocytes. ( Marselos, M; Michalopoulos, G; Strom, SC, 1987) |
| "MeCh both reduced the incidence of hepatic neoplasms induced by 3'-MeDAB and delayed their development." | 1.26 | 3-Methylcholanthrene-inhibition of hepatocarcinogenesis in the rat due to 3'-methyl-4-dimethylaminoazobenzene or 2-acetylamino-fluorene: a comparative study. ( Flaks, A; Flaks, B, 1982) |
| "In well differentiated, slowly growing hepatomas, the concentration of GSH approached the level in normal adult rat liver." | 1.26 | Glutathione and gamma glutamyl transpeptidase in rat liver during chemical carcinogenesis. ( Fiala, AE; Fiala, S; Kettering, WG; Mohindru, A; Morris, HP, 1976) |
| "These neoplasms included cholangiomas, hepatoadenomas, cholangiocarcinomas, and hepatocellular cancers." | 1.25 | Tumor induction by carcinogenic agents in aquarium fish. ( Khudoley, VV; Pliss, GB, 1975) |
| "DNA synthesis in a transplanted hepatoma induced by 3'-methyl-4-dimethylaminoazobenzene was significantly reduced (P less than 0." | 1.25 | Zinc intake, neoplastic DNA synthesis, and chemical carcinogenesis in rats and mice. ( Dreosti, IE; Duncan, JR, 1975) |
| "2." | 1.25 | Effects of 3-methylcholanthrene pretreatment on microsomal hydroxylation of 2-acetamidofluorene by various rat hepatomas. ( Lotlikar, PD, 1970) |
| "The hepatomata are all predominantly hepatocellular carcinomata and the sarcomata comprise two liposarcomata and a fibrosarcoma." | 1.25 | The induction of tumours in the guinea-pig with methylcholanthrene and diethylnitrosamine and their propagation in vivo and in vitro. ( Andjargholi, M; Dale, MM; Desai, H; Easty, GC; Tchao, R, 1973) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 118 (79.73) | 18.7374 |
| 1990's | 14 (9.46) | 18.2507 |
| 2000's | 11 (7.43) | 29.6817 |
| 2010's | 5 (3.38) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Utgikar, R | 1 |
| Riddick, DS | 2 |
| Hosaka, T | 1 |
| Sekimoto, M | 1 |
| Nemoto, K | 1 |
| Degawa, M | 1 |
| EISEN, MJ | 1 |
| Volkov, MS | 1 |
| Kobliakov, VA | 1 |
| Remeseiro, S | 1 |
| Cuadrado, A | 1 |
| Carretero, M | 1 |
| Martínez, P | 1 |
| Drosopoulos, WC | 1 |
| Cañamero, M | 1 |
| Schildkraut, CL | 1 |
| Blasco, MA | 1 |
| Losada, A | 1 |
| Bhattacharya, S | 1 |
| Haldar, PK | 1 |
| MEECHAN, RJ | 1 |
| McCAFFERTY, DE | 1 |
| JONES, RS | 1 |
| KLEIN, M | 3 |
| ODASHIMA, S | 4 |
| KITAURA, K | 1 |
| YAMADA, H | 1 |
| MIYAZI, T | 1 |
| KUHN, O | 1 |
| KOECKE, HU | 1 |
| BAIN, GO | 1 |
| SIEGENBERG, J | 1 |
| KOWALEWSKI, K | 1 |
| MAISIN, J | 1 |
| USUBUCHI, I | 1 |
| CONNEY, AH | 2 |
| BURNS, JJ | 1 |
| POTTER, VR | 2 |
| KIKUCHI, K | 2 |
| TSUJI, Y | 1 |
| ITAKURA, K | 1 |
| KATAGIRI, H | 1 |
| MALLARD, JR | 1 |
| KENT, M | 1 |
| ISHIDATE, M | 2 |
| RICHARDSON, HL | 1 |
| STIER, AR | 1 |
| BORSOS-NACHTNEBEL, E | 1 |
| Kasai, A | 1 |
| Hiramatsu, N | 1 |
| Meng, Y | 1 |
| Yao, J | 1 |
| Takeda, M | 1 |
| Maeda, S | 1 |
| Kitamura, M | 1 |
| Sun, H | 1 |
| Liu, GT | 1 |
| Finel, M | 1 |
| Li, X | 1 |
| Gardner-Stephen, D | 1 |
| Bratton, S | 1 |
| Mackenzie, PI | 1 |
| Radominska-Pandya, A | 1 |
| Smith, CM | 1 |
| Graham, RA | 1 |
| Krol, WL | 1 |
| Silver, IS | 1 |
| Negishi, M | 1 |
| Wang, H | 1 |
| Lecluyse, EL | 1 |
| Shipley, JM | 1 |
| Waxman, DJ | 1 |
| Sawaya, RM | 1 |
| Marchant, J | 1 |
| Blunck, JM | 1 |
| Smith, ML | 1 |
| Vorrath, EM | 1 |
| Lambiotte, M | 1 |
| Thierry, N | 1 |
| Edel, G | 1 |
| Grundmann, E | 1 |
| Yin, Z | 1 |
| Sato, K | 2 |
| Tsuda, H | 1 |
| Ito, N | 5 |
| Flaks, A | 1 |
| Flaks, B | 1 |
| Brauer, M | 1 |
| Inculet, RI | 1 |
| Bhatnagar, G | 1 |
| Marsh, GD | 1 |
| Driedger, AA | 1 |
| Thompson, RT | 1 |
| Quattrochi, LC | 1 |
| Vu, T | 1 |
| Tukey, RH | 1 |
| Rosenberg, DW | 1 |
| Leff, T | 1 |
| Nicod, L | 1 |
| Viollon, C | 1 |
| Regnier, A | 1 |
| Jacqueson, A | 1 |
| Richert, L | 1 |
| Kim, HC | 1 |
| Lee, YS | 1 |
| Nishikawa, A | 1 |
| Ainbinder, E | 1 |
| Bergelson, S | 1 |
| Daniel, V | 1 |
| Galijatovic, A | 1 |
| Otake, Y | 1 |
| Walle, UK | 1 |
| Walle, T | 1 |
| Sotiropoulou, M | 1 |
| Pappas, P | 1 |
| Marselos, M | 2 |
| Guigal, N | 1 |
| Seree, E | 1 |
| Nguyen, QB | 1 |
| Charvet, B | 1 |
| Desobry, A | 1 |
| Barra, Y | 1 |
| Anis, KV | 1 |
| Rajeshkumar, NV | 1 |
| Kuttan, R | 1 |
| Mizesko, MC | 1 |
| Grewe, C | 1 |
| Grabner, A | 1 |
| Miller, MS | 1 |
| Cretney, E | 1 |
| Takeda, K | 1 |
| Yagita, H | 1 |
| Glaccum, M | 1 |
| Peschon, JJ | 1 |
| Smyth, MJ | 1 |
| Watanabe, M | 4 |
| Konno, K | 2 |
| Sato, H | 2 |
| Fiala, S | 1 |
| Mohindru, A | 1 |
| Kettering, WG | 1 |
| Fiala, AE | 1 |
| Morris, HP | 3 |
| Nagasaki, H | 1 |
| Kawabata, H | 1 |
| Miyata, Y | 1 |
| Inoue, K | 1 |
| Hirao, K | 2 |
| Aoe, H | 1 |
| Tatematsu, M | 1 |
| Lafond, MG | 1 |
| Calabrese, EJ | 1 |
| Pimm, MV | 4 |
| Baldwin, RW | 8 |
| Schneeweiss, U | 1 |
| Fabricius, EA | 1 |
| Pliss, GB | 1 |
| Khudoley, VV | 1 |
| Duncan, JR | 1 |
| Dreosti, IE | 1 |
| Sakamoto, M | 1 |
| Nishioka, K | 1 |
| Zöller, M | 1 |
| Price, MR | 2 |
| Williams, MT | 1 |
| Gaylor, JL | 1 |
| Kovalszky, I | 1 |
| Jeney, A | 1 |
| Asbót, R | 1 |
| Lapis, K | 1 |
| Yumura, M | 1 |
| Matsushima, T | 1 |
| Sugimura, T | 2 |
| Brooks, CG | 1 |
| Rees, RC | 1 |
| Gessner, T | 1 |
| Kjartansson, I | 1 |
| Miller, FR | 1 |
| Blazkovec, AA | 1 |
| Dennick, RG | 1 |
| Law, LW | 1 |
| Reynolds, ES | 1 |
| Moslen, MT | 1 |
| Szabo, S | 1 |
| Jaeger, RJ | 1 |
| Murphy, SD | 1 |
| Appel, KE | 1 |
| Rickart, R | 1 |
| Schwarz, M | 2 |
| Kunz, HW | 1 |
| Sivak, A | 1 |
| Thorgeirsson, SS | 1 |
| Sakai, S | 1 |
| Adamson, RH | 1 |
| Levin, W | 1 |
| Buening, MK | 1 |
| Wood, AW | 1 |
| Chang, RL | 1 |
| Thakker, DR | 1 |
| Jerina, DM | 1 |
| Hirao, F | 1 |
| Yamamura, Y | 1 |
| Grover, PL | 1 |
| Sims, P | 1 |
| Mitchley, BC | 1 |
| Roe, FJ | 2 |
| Reuber, MD | 2 |
| Belisario, MA | 1 |
| Arena, AR | 1 |
| Pecce, R | 1 |
| Borgia, R | 1 |
| Staiano, N | 1 |
| De Lorenzo, F | 1 |
| Visser, O | 1 |
| van den Berg, JW | 1 |
| Koole-Lesuis, H | 1 |
| Voortman, G | 1 |
| Wilson, JH | 1 |
| Carubelli, R | 1 |
| Graham, SA | 1 |
| McCay, PB | 1 |
| Friedman, FK | 1 |
| Gallinger, S | 1 |
| Hoskin, DW | 1 |
| Mullen, JB | 1 |
| Wong, AH | 1 |
| Roder, JC | 1 |
| Fandrey, J | 1 |
| Seydel, FP | 1 |
| Siegers, CP | 1 |
| Jelkmann, W | 1 |
| Wiebel, FJ | 1 |
| Cikryt, P | 1 |
| Blaich, G | 1 |
| Raabe, H | 1 |
| Metzler, M | 1 |
| Iwasa, F | 1 |
| Sassa, S | 1 |
| Kappas, A | 1 |
| Bock, KW | 1 |
| Bock-Hennig, BS | 1 |
| Hayes, MA | 1 |
| Roberts, E | 1 |
| Safe, SH | 1 |
| Farber, E | 2 |
| Cameron, RG | 1 |
| Strom, SC | 1 |
| Michalopoulos, G | 1 |
| Aterman, K | 1 |
| Buchmann, A | 1 |
| Schmitt, R | 1 |
| Wolf, CR | 1 |
| Oesch, F | 1 |
| Kunz, W | 1 |
| Pickett, CB | 1 |
| Telakowski-Hopkins, CA | 1 |
| Ding, GJ | 1 |
| Ding, VD | 1 |
| King, RG | 1 |
| Yoshimoto, F | 1 |
| Masuda, S | 1 |
| Higashi, T | 1 |
| Nishii, T | 1 |
| Takamisawa, I | 1 |
| Tateishi, N | 1 |
| Sakamoto, Y | 1 |
| Warren, RS | 1 |
| Jeevanandam, M | 1 |
| Brennan, MF | 1 |
| Shimkin, MB | 1 |
| Sheth, NA | 1 |
| Wagle, M | 1 |
| Bhide, SV | 1 |
| Ranadive, KJ | 1 |
| Ikeda, K | 1 |
| Hozumi, M | 1 |
| Dmochowski, L | 1 |
| Rogers, T | 1 |
| Liebelt, AG | 2 |
| Liebelt, RA | 3 |
| Sykes, JA | 1 |
| Peterson, HI | 1 |
| Rudenstam, CM | 3 |
| Schindler, R | 1 |
| Doerner, KF | 1 |
| Sanford, S | 1 |
| Sobbe, A | 1 |
| Haferkamp, O | 1 |
| Yamafuji, K | 1 |
| Uchida, Y | 1 |
| Walters, MA | 1 |
| Krüger, G | 2 |
| Pogosiants, EE | 1 |
| Sokova, OI | 1 |
| Prigozhina, EL | 1 |
| Lotlikar, PD | 1 |
| Bresnick, E | 1 |
| Mayfield, ED | 1 |
| Kondrat'eva, AF | 1 |
| Barker, CR | 1 |
| Embleton, MJ | 1 |
| Glaves, D | 3 |
| Moore, M | 1 |
| Homburger, F | 1 |
| Vose, BM | 2 |
| Kimura, I | 1 |
| Miyake, T | 1 |
| Ishimoto, A | 1 |
| Ito, Y | 1 |
| Makiura, S | 1 |
| Kamamoto, Y | 1 |
| Sugihara, S | 1 |
| Hiasa, Y | 3 |
| Dale, MM | 1 |
| Easty, GC | 1 |
| Tchao, R | 1 |
| Desai, H | 1 |
| Andjargholi, M | 1 |
| Benedict, WF | 1 |
| Gielen, JE | 1 |
| Owens, IS | 1 |
| Niwa, A | 1 |
| Bebert, DW | 1 |
| Kuroda, J | 1 |
| Saito, S | 1 |
| Seno, N | 1 |
| Nagase, S | 1 |
| Anno, K | 1 |
| Akamatsu, Y | 1 |
| Barton, BP | 1 |
| Decloitre, F | 1 |
| Chauveau, J | 1 |
| Martin, M | 1 |
| Cook, AJ | 1 |
| Hopper, DG | 1 |
| Proctor, JW | 1 |
| Alexander, P | 1 |
| Southam, CM | 2 |
| Odashima, H | 1 |
| Argus, MF | 3 |
| Sohal, RS | 1 |
| Bryant, GM | 1 |
| Hoch-Ligeti, C | 2 |
| Arcos, JC | 3 |
| Turusov, VS | 1 |
| Breslow, NE | 1 |
| Tomatis, L | 1 |
| Heidelberger, C | 1 |
| Marugami, M | 2 |
| Konishi, Y | 2 |
| Toth, B | 1 |
| Irving, CC | 2 |
| Veazey, RA | 2 |
| Boeryd, B | 4 |
| Hallgren, B | 1 |
| Ställberg, G | 1 |
| Peeler, TC | 1 |
| Wiseman, R | 1 |
| Laws, ER | 1 |
| Mirvish, SS | 1 |
| Sidransky, H | 1 |
| Ritter, K | 1 |
| Reiner, J | 1 |
| Domellöf, L | 1 |
| Vaage, J | 1 |
| Chen, K | 1 |
| Merrick, S | 1 |
| Walder, JA | 1 |
| Fabian, JA | 1 |
| Enomoto, M | 1 |
| Miyake, M | 1 |
| Mellgren, J | 1 |
| Bartholdsson, E | 1 |
| Norrby, K | 1 |
9 reviews available for 3-methylcholanthrene and Liver Neoplasms
| Article | Year |
|---|---|
[Some contributions by chemical carcinogenesis--what is the animal model of human cancer? (author's transl)].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Cricetinae; Disease Models, Animal; Dogs; | 1978 |
Is the selenium drinking water standard justified?
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adolescent; Animals; Antineoplastic Agents; Carcinogens; Chromosom | 1979 |
Experimental carcinogenesis in small aquarium fishes.
Topics: 2-Acetylaminofluorene; Adenoma; Adenoma, Bile Duct; Aflatoxins; Animals; Benzopyrenes; Carcinogens; | 1976 |
Cocarcinogenesis.
Topics: 2-Acetylaminofluorene; Animals; Carcinogens; Cell Transformation, Viral; Cocarcinogenesis; Diet; Gas | 1979 |
Immunological aspects of chemical carcinogenesis.
Topics: Animals; Antibody Formation; Antigens, Neoplasm; Antilymphocyte Serum; Azo Compounds; Benz(a)Anthrac | 1973 |
[The combined action of ionizing radiation and carcinogens].
Topics: Animals; Benz(a)Anthracenes; Bone Neoplasms; Carbon Tetrachloride Poisoning; Carcinogens; Carcinoma, | 1969 |
Areas of relationship between immunology and clinical oncology.
Topics: Adenocarcinoma; Allergy and Immunology; Animals; Antigens, Neoplasm; Antineoplastic Agents; Carcinoe | 1974 |
Chemical carcinogenesis, chemotherapy: cancer's continuing core challenges--G. H. A. Clowes Memorial Lecture.
Topics: Animals; Antineoplastic Agents; Arginase; Benz(a)Anthracenes; Benzopyrenes; Carcinogens; Cell Divisi | 1970 |
A critical review of experiments in chemical carcinogensis using newborn animals.
Topics: Age Factors; Animals; Animals, Newborn; Anthracenes; Benz(a)Anthracenes; Carcinogens; Cricetinae; Ha | 1968 |
139 other studies available for 3-methylcholanthrene and Liver Neoplasms
| Article | Year |
|---|---|
Downregulation of cytochrome P450 2C8 by 3-methylcholanthrene in human hepatocellular carcinoma cell lines.
Topics: Carcinoma, Hepatocellular; Cytochrome P-450 CYP2C8; Down-Regulation; Hep G2 Cells; Humans; Liver Neo | 2017 |
Augmentation of 3-methylcholanthrene-induced bioactivation in the human hepatoma cell line HepG2 by the calcium channel blocker nicardipine.
Topics: Aryl Hydrocarbon Hydroxylases; Calcium Channel Blockers; Carcinoma, Hepatocellular; Cell Line, Tumor | 2010 |
Induction of sarcoma of the liver in the rat with methylcholanthrene and benzpyrene.
Topics: Animals; Benzopyrenes; Liver Neoplasms; Methylcholanthrene; Neoplasms; Rats; Sarcoma, Experimental | 1946 |
[Activation of transcription factor NF-kappaB by carcinogenic polycyclic aromatic hydricarbons].
Topics: Actins; Animals; Benzo(a)pyrene; Carcinogens; Carcinoma, Hepatocellular; Cell Line, Tumor; Genes, Re | 2011 |
Cohesin-SA1 deficiency drives aneuploidy and tumourigenesis in mice due to impaired replication of telomeres.
Topics: Aneuploidy; Animals; Carcinogens; Cell Cycle Proteins; Cell Line; Chromatids; Chromosomal Proteins, | 2012 |
Chemopreventive property of Trichosanthes dioica root against 3-methylcholanthrene-induced carcinogenesis in albino mice.
Topics: Animals; Catalase; Chemoprevention; Disease Models, Animal; Fibrosarcoma; Glutathione; Glutathione T | 2012 |
3-Methylcholanthrene as an inhibitor of hepatic cancer induced by 3'-methyl-4-dimethylaminoazobenzene in the diet of the rat: a determination of the time relationships.
Topics: Animals; Bile Duct Neoplasms; Diet; Liver Neoplasms; Methylcholanthrene; Methyldimethylaminoazobenze | 1953 |
Induction of tumors in mice following intrasplenic or intrahepatic transplantation of fetal skin, muscle, or stomach with methylcholanthrene.
Topics: Animals; Liver Neoplasms; Methylcholanthrene; Mice; Muscles; Neoplasms; Skin Transplantation; Spleen | 1954 |
Effect of p-(naphthol-2-azo-1) benzoxyethyl bis (beta-chloroethyl) amine on the methylcholanthrene tumors in mice and azo-dye hepatoma in rats.
Topics: Amines; Animals; Carcinoma, Hepatocellular; Liver Neoplasms; Mechlorethamine; Methylcholanthrene; Mi | 1956 |
[Effects of chrysene and 3-methylcholanthrene on DAB-induced liver tumors].
Topics: Animals; Carcinogens; Chrysenes; Hydrocarbons; Liver Neoplasms; Liver Neoplasms, Experimental; Methy | 1957 |
[Local effect of methylcholanthrene on the liver of the mouse and the problem of primary liver carcinoma].
Topics: Animals; Liver Neoplasms; Liver Neoplasms, Experimental; Methylcholanthrene; Mice; Sarcoma, Experime | 1957 |
Combine effect of carcinogens with different actions. II. Effect of pretreatment of painting with 20-methylcholanthrene or feeding of 4-dimethylaminostilbene upon carcinogenesis of 4-dimethylaminoazobenzene in the rat.
Topics: Animals; Carcinogenesis; Carcinogens; Liver Neoplasms; Methylcholanthrene; Neoplasms; Neoplasms, Exp | 1962 |
Further studies on methylcholanthrene-induced tumours of the gallbladder and liver in the golden hamster.
Topics: Animals; Cricetinae; Gallbladder Neoplasms; Humans; Liver Neoplasms; Mesocricetus; Methylcholanthren | 1963 |
SUSCEPTIBILITY OF STRAIN B6AF1-J HYBRID INFANT MICE TO TUMORIGENESIS WITH 1,2-BENZANTHRACENE, DEOXYCHOLIC ACID, AND 3-METHYLCHOLANTHRENE.
Topics: Animals; Animals, Newborn; Benz(a)Anthracenes; Bile Acids and Salts; Carcinogenesis; Carcinogens; Ca | 1963 |
[ATTEMPTED IMMUNOPROPHYLAXIS OF EXPERIMENTALLY INDUCED CANCERS].
Topics: Animals; Carcinoma, Hepatocellular; Immunization; Liver Neoplasms; Methylcholanthrene; Mice; Neoplas | 1964 |
ADMINISTRATION METHOD OF MITOMYCIN C.
Topics: Carcinoma, Hepatocellular; Liver Neoplasms; Methylcholanthrene; Mitomycin; Mitomycins; Neoplasms; Ne | 1964 |
INDUCED SYNTHESIS OF OXIDATIVE ENZYMES IN LIVER MICROSOMES BY POLYCYCLIC HYDROCARBONS AND DRUGS.
Topics: Aminopyrine; Androgens; Benzopyrenes; Carbohydrate Metabolism; Carcinoma, Hepatocellular; Ethionine; | 1963 |
BIOCHEMISTRY OF REGULATION OF ENZYME ACTIVITY AND SYNTHESIS. SESSION CHAIRMAN'S COMMENTS.
Topics: Adenosine Triphosphate; Biochemistry; Carcinoma, Hepatocellular; Feedback; Liver; Liver Neoplasms; M | 1963 |
A CASE OF METASTASES OF GASTRIC CANCER TO HYPERNEPHROMA AND ITS METASTATIC FOCI.
Topics: Adenocarcinoma; Carcinoma, Hepatocellular; Carcinoma, Renal Cell; Kidney Neoplasms; Liver Neoplasms; | 1964 |
DIFFERENCES OBSERVED BETWEEN ELECTRON SPIN RESONANCE SIGNALS FROM SURVIVING TUMOUR TISSUES AND FROM THEIR CORRESPONDING NORMAL TISSUES.
Topics: Electron Spin Resonance Spectroscopy; Fibrosarcoma; Kidney; Kidney Neoplasms; Liver; Liver Neoplasms | 1964 |
COMBINED EFFECT OF CARCINOGENS AND CO-CARCINOGENS ON METABOLIC PROCESS.
Topics: Carcinogens; Liver; Liver Neoplasms; Methylcholanthrene; Neoplasms; Neoplasms, Experimental; p-Dimet | 1964 |
Development of hepatomas in inbred albino mice following treatment with 20-methylcholanthrene.
Topics: Animals; Carcinoma, Hepatocellular; Liver Neoplasms; Liver Neoplasms, Experimental; Methylcholanthre | 1959 |
Development of liver cancers in the rat by 20-methylcholanthrene painting following initial 4-dimethylaminoazobenzene feeding.
Topics: Animals; Bile Ducts, Intrahepatic; Carcinogens; Liver Neoplasms; Liver Neoplasms, Experimental; Meth | 1959 |
Liver tumor inhibition and adrenal histologic responses in rats to which 3'-methyl-4-dimethylaminoazobenzene and 20-methylcholanthrene were simultaneously administered.
Topics: Animals; Liver Neoplasms; Methylcholanthrene; Methyldimethylaminoazobenzene; Neoplasms, Experimental | 1952 |
DRESSA: biosensing of dioxin and dioxin-like chemicals using secreted alkaline phosphatase.
Topics: Alkaline Phosphatase; Animals; Benzo(a)pyrene; beta-Naphthoflavone; Carcinoma, Hepatocellular; Cytoc | 2004 |
Chemopreventive effect of bicyclol on malignant transformation of WB-F344 rat liver epithelial cells and its effect on related signal transduction in vitro.
Topics: Animals; Antineoplastic Agents; Benz(a)Anthracenes; Biphenyl Compounds; Cell Communication; Cell Lin | 2006 |
Human UDP-glucuronosyltransferase 1A5: identification, expression, and activity.
Topics: Adult; Aged; Amino Acid Sequence; Animals; Baculoviridae; Caco-2 Cells; Carcinoma, Hepatocellular; C | 2005 |
Differential UGT1A1 induction by chrysin in primary human hepatocytes and HepG2 Cells.
Topics: Adolescent; Adult; Aged; Black People; Carcinogens; Carcinoma, Hepatocellular; Cell Line, Tumor; Cel | 2005 |
Aryl hydrocarbon receptor-independent activation of estrogen receptor-dependent transcription by 3-methylcholanthrene.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Dose-Response Relationship, Drug; Endometrial Neoplasms | 2006 |
Cytochrome P450 2C11 5'-flanking region and promoter: regulation by aromatic hydrocarbons in vitro.
Topics: 5' Flanking Region; Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Carcinoma, Hepatocellular | 2008 |
The effects of different social conditions on breast cancer induction in three genetic types of mice by dibenz[a,h]anthracene and a comparison with breast carcinogenesis by 3-methylcholanthrene.
Topics: Animals; Behavior, Animal; Benz(a)Anthracenes; Estrogens; Female; Genetics; Lactation; Liver Neoplas | 1967 |
A series of inhibitors of azo dye hepatocarcinogenesis partially reverse the azo dye-induced decrease in liver RNA/DNA ratio.
Topics: Acetanilides; Animals; Antineoplastic Agents; Butylated Hydroxytoluene; DNA; Hydroxypropiophenone; L | 1982 |
Glucocorticoid enhancement of aflatoxin B1 cytotoxicity in differentiated rat hepatoma cultures.
Topics: Aflatoxin B1; Aflatoxins; Animals; Biotransformation; Carcinoma, Hepatocellular; Cell Differentiatio | 1980 |
Selection of liver-colonizing tumor cells from a murine fibrosarcoma induced by methylcholanthrene.
Topics: Animals; Clone Cells; Female; Fibrosarcoma; Injections, Intravenous; Liver Neoplasms; Lung Neoplasms | 1984 |
Changes in activities of uridine diphosphate-glucuronyltransferases during chemical hepatocarcinogenesis.
Topics: 2-Acetylaminofluorene; Animals; Butylated Hydroxyanisole; Diethylnitrosamine; Enzyme Induction; Gluc | 1982 |
3-Methylcholanthrene-inhibition of hepatocarcinogenesis in the rat due to 3'-methyl-4-dimethylaminoazobenzene or 2-acetylamino-fluorene: a comparative study.
Topics: 2-Acetylaminofluorene; Animals; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Methylcholanth | 1982 |
Insulin protects against hepatic bioenergetic deterioration induced by cancer cachexia: an in vivo 31P magnetic resonance spectroscopy study.
Topics: Adenosine Triphosphate; Animals; Body Weight; Cachexia; Eating; Energy Metabolism; Fibrosarcoma; Ins | 1994 |
The human CYP1A2 gene and induction by 3-methylcholanthrene. A region of DNA that supports AH-receptor binding and promoter-specific induction.
Topics: Animals; Base Sequence; Binding Sites; Carcinoma, Hepatocellular; Cell Line; Cell Nucleus; Cytochrom | 1994 |
Regulation of cytochrome P450 in cultured human colonic cells.
Topics: Adenocarcinoma; Animals; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; beta-Naphthoflavone; Carcinoma | 1993 |
Rifampicin and isoniazid increase acetaminophen and isoniazid cytotoxicity in human HepG2 hepatoma cells.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Antitubercular Agents; Carcinoma, Hepatocellular; Cell Surv | 1997 |
Enhancing effects of phenobarbital and 3-methylcholanthrene on GST-P-positive liver cell foci development in a new medium-term rat liver bioassay using D-galactosamine.
Topics: Animals; Biological Assay; Blood Chemical Analysis; Body Weight; Carcinogens; Diet; Diethylnitrosami | 1997 |
Signaling pathways in the induction of c-fos and c-jun proto-oncogenes by 3-methylcholanthrene.
Topics: Calcium-Calmodulin-Dependent Protein Kinases; Carcinoma, Hepatocellular; Chloramphenicol O-Acetyltra | 1997 |
Extensive metabolism of the flavonoid chrysin by human Caco-2 and Hep G2 cells.
Topics: Animals; Apigenin; Arylsulfotransferase; Caco-2 Cells; Carcinoma, Hepatocellular; Cell Line; Chromat | 1999 |
Effects of 3-methylcholanthrene and aspirin co-administration on ALDH3A1 in HepG2 cells.
Topics: Aldehyde Dehydrogenase; Aspirin; Carcinoma, Hepatocellular; Cell Survival; Drug Interactions; Glutat | 2001 |
Serum induces a transcriptional activation of CYP1A1 gene in HepG2 independently of the AhR pathway.
Topics: Adenocarcinoma; Animals; Blood; Carcinoma, Hepatocellular; Cattle; Chloramphenicol O-Acetyltransfera | 2001 |
Inhibition of chemical carcinogenesis by berberine in rats and mice.
Topics: Alkylating Agents; Animals; Berberine; Cell Transformation, Neoplastic; Diethylnitrosamine; Dose-Res | 2001 |
Alterations at the Ink4a locus in transplacentally induced murine lung tumors.
Topics: Animals; Base Sequence; Carcinogens; Cyclin-Dependent Kinase Inhibitor p16; DNA Methylation; Genes, | 2001 |
Increased susceptibility to tumor initiation and metastasis in TNF-related apoptosis-inducing ligand-deficient mice.
Topics: Adenocarcinoma; Animals; Apoptosis Regulatory Proteins; Cell Division; Cell Transformation, Neoplast | 2002 |
Properties of aryl hydrocarbon hydroxylase in microsomes of Morris hepatoma 5123D and the host liver.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Carcinoma, Hepatocellular; Epoxide Hydrolases; Flavonoids; H | 1975 |
Glutathione and gamma glutamyl transpeptidase in rat liver during chemical carcinogenesis.
Topics: 2-Acetylaminofluorene; Animals; Carcinoma, Hepatocellular; Chloramphenicol; gamma-Glutamyltransferas | 1976 |
Effect of various factors on induction of liver tumors in animals by the alpha-isomer of benzene hexachloride.
Topics: Animals; Body Weight; Carcinogens; Cricetinae; Female; Hexachlorocyclohexane; Hydroxypropiophenone; | 1975 |
BCG therapy of pleural and peritoneal growth of transplanted rat tumours.
Topics: Animals; Azo Compounds; BCG Vaccine; Benzene; Breast Neoplasms; Carcinoma, Hepatocellular; Female; F | 1975 |
[The tumor-tetanus assay--experimental studies on the biological differentiation between carcinogenesis and organ regeneration of the rat (author's transl)].
Topics: Agglutination Tests; Animals; Antibodies, Neoplasm; Antibody Formation; Carcinoma 256, Walker; Carci | 1975 |
Tumor induction by carcinogenic agents in aquarium fish.
Topics: 2-Acetylaminofluorene; 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenoma; Adenoma, Bile Duct | 1975 |
Zinc intake, neoplastic DNA synthesis, and chemical carcinogenesis in rats and mice.
Topics: Animals; Carcinoma, Hepatocellular; Depression, Chemical; DNA, Neoplasm; Dose-Response Relationship, | 1975 |
Studies on rat complement. II. Complement level in experimental tumor in rats.
Topics: Animals; Carcinoma, Hepatocellular; Complement C3; Complement C4; Complement System Proteins; Coryne | 1975 |
Inhibition of cell-mediated cytotoxicity to chemically induced rat tumours by soluble tumour and embryo cell extracts.
Topics: Animals; Antigens, Neoplasm; Azo Compounds; Carcinoembryonic Antigen; Carcinoma, Hepatocellular; Cel | 1976 |
Axyl hydrocarbon hydroxylase in Morris hepatoma 5123D.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Carcinoma, Hepatocellular; Cell Nucleus; Female; Flavonoids; | 1975 |
Characterization of microsomal methyl sterol demethylase in two Morris hepatomas.
Topics: Animals; Buffers; Carcinoma, Hepatocellular; Cholesterol; Cholestyramine Resin; Cyanides; Cytochrome | 1976 |
Biochemistry and enzyme induction in MC-29 virus-induced transplantable avian hepatoma.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Carcinoma, Hepatocellular; Cell Nucleus; Chickens; Cytoplasm | 1976 |
Macrophage migration inhibition-activity after implantation of methylcholanthrene-induced sarcoma, Ehrlich ascites cancer or mouse ascites hepatoma-134 cancer cells in mice.
Topics: Animals; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Cell Migration Inhibition; Immunity, C | 1976 |
Studies on the microcytotoxicity test. I. Evidence that the effects of normal lymphoid cells on tumour cell growth in microtest plates may be caused by non-immunological modifications of the culture medium.
Topics: Animals; Carcinoma, Hepatocellular; Cell Fractionation; Cell Transformation, Neoplastic; Culture Med | 1976 |
A comparison of steroid glucuronlytransferases of rat liver and hepatoma, and effects of phenobarbitone and 3-methylcholanthrene induction.
Topics: Animals; Carcinoma, Hepatocellular; Enzyme Induction; Estradiol; Estrone; Glucuronosyltransferase; K | 1976 |
Tumour circulation. An experimental study in the rat with a comparison of different methods for estimation of tumour blood flow.
Topics: Angiography; Animals; Antipyrine; Carcinoma, Hepatocellular; Iodine Radioisotopes; Liver Neoplasms; | 1976 |
Guinea pig cell-mediated tumor immunity: the chromium release assay detects both cytolysis and serum blocking for syngeneic chemically-induced tumors.
Topics: Animals; Binding, Competitive; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Chromium | 1979 |
Effect of heat and glutaraldehyde upon the immunogenicity of Meth A sarcoma cells.
Topics: Aldehydes; Animals; Antigens, Neoplasm; Carcinoma, Hepatocellular; Glutaral; Hot Temperature; Immuni | 1979 |
Hepatotoxicity of vinyl chloride and 1,1-dichloroethylene. Role of mixed function oxidase system.
Topics: Animals; Aroclors; Carcinogens; Cell Membrane; Cytochrome P-450 Enzyme System; Dichloroethylenes; En | 1975 |
Influence of drugs on activation and inactivation of hepatocarcinogenic nitrosamines.
Topics: Alkylation; Animals; Biotransformation; Carcinogens; DNA; Liver Neoplasms; Male; Methylcholanthrene; | 1979 |
Induction of monooxygenases in rhesus monkeys by 3-methylcholanthrene: metabolism and mutagenic activation of N-2-acetylaminofluorene and benzo(a)pyrene.
Topics: 2-Acetylaminofluorene; Animals; Aryl Hydrocarbon Hydroxylases; Benzopyrenes; Cytochrome P-450 Enzyme | 1978 |
Tumorigenic activity of 3-methylcholanthrene metabolites on mouse skin and in newborn mice.
Topics: Administration, Topical; Animals; Animals, Newborn; Carcinogens; Cocarcinogenesis; Drug Administrati | 1979 |
Comparison of lung cancer and amyloidosis in rabbits induced by chemical carcinogens.
Topics: 4-Nitroquinoline-1-oxide; Amyloidosis; Animals; Bronchi; Carcinogens; Female; Liver Neoplasms; Lung | 1975 |
The carcinogenicity of polycyclic hydrocarbon epoxides in newborn mice.
Topics: Animals; Animals, Newborn; Benz(a)Anthracenes; Chrysenes; Ethers, Cyclic; Female; Liver Neoplasms; L | 1975 |
Protection by methylcholanthrene against hepatic carcinogenesis in rats ingesting N-4-(4'-fluorobiphenyl) acetamide.
Topics: Aminobiphenyl Compounds; Animals; Carcinogens; Carcinoma; Kidney Neoplasms; Liver Neoplasms; Lung Ne | 1976 |
Effect of enzyme inducers on metabolism of 1-nitropyrene in human hepatoma cell line HepG2.
Topics: Carcinoma, Hepatocellular; Enzyme Induction; Humans; Liver Neoplasms; Methylcholanthrene; Mutagens; | 1991 |
Porphyrin synthesis by human hepatocytes and HepG2 cells--effects of enzyme inducers and delta-aminolevulinic acid.
Topics: Aminolevulinic Acid; Carcinoma, Hepatocellular; Cells, Cultured; Cytochrome P-450 Enzyme System; Dim | 1991 |
Prevention of 2-acetylaminofluorene-induced loss of nuclear envelope cytochrome P450 by the simultaneous administration of 3-methylcholanthrene.
Topics: 2-Acetylaminofluorene; Animals; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; | 1991 |
Comparison of cellular immunotherapies and anti-CD3 in the treatment of MCA-38-LD experimental hepatic metastases in C57BL/6 mice.
Topics: Adenocarcinoma; Animals; Antigens, Differentiation, T-Lymphocyte; Brain Neoplasms; CD3 Complex; Cell | 1990 |
Role of cytochrome P450 in the control of the production of erythropoietin.
Topics: Carcinoma, Hepatocellular; Cobalt; Cysteamine; Cytochrome P-450 Enzyme System; Ditiocarb; Erythropoi | 1990 |
Dexamethasone-mediated potentiation of P450IA1 induction in H4IIEC3/T hepatoma cells is dependent on a time-consuming process and associated with induction of the Ah receptor.
Topics: Animals; Benzo(a)pyrene; Carcinoma, Hepatocellular; Cytochrome P-450 Enzyme System; Cytosol; Dexamet | 1990 |
Modification of 7,8-benzoflavone metabolism in hamster liver and kidney microsomes by hepatic tumor inducing treatments.
Topics: Animals; Benzoflavones; Biotransformation; Carcinogens; Cricetinae; Diethylstilbestrol; Flavonoids; | 1990 |
delta-Aminolaevulinate synthase in human HepG2 hepatoma cells. Repression by haemin and induction by chemicals.
Topics: 5-Aminolevulinate Synthetase; Carcinoma, Hepatocellular; Dimethyl Sulfoxide; Dose-Response Relations | 1989 |
Differential induction of human liver UDP-glucuronosyltransferase activities by phenobarbital-type inducers.
Topics: Acetaminophen; Adolescent; Adult; Benzopyrenes; Bilirubin; Carcinoma, Hepatocellular; Enzyme Inducti | 1987 |
Influences of different polychlorinated biphenyls on cytocidal, mitoinhibitory, and nodule-selecting activities of N-2-fluorenylacetamide in rat liver.
Topics: 2-Acetylaminofluorene; Animals; Cell Survival; gamma-Glutamyltransferase; Hepatectomy; Liver; Liver | 1986 |
Effect of phenobarbital and 3-methylcholanthrene on aldehyde dehydrogenase activity in cultures of HepG2 cells and normal human hepatocytes.
Topics: Aldehyde Dehydrogenase; Aldehydes; Benzaldehydes; Carcinoma, Hepatocellular; Cells, Cultured; Liver; | 1987 |
Localized hepatocarcinogenesis: the response of the liver and kidney to implanted carcinogens.
Topics: Animals; Carcinogens; Drug Implants; Kidney Neoplasms; Liver Neoplasms; Liver Neoplasms, Experimenta | 1987 |
Development of cytochrome P-450-altered preneoplastic and neoplastic lesions during nitrosamine-induced hepatocarcinogenesis in the rat.
Topics: Animals; Cell Differentiation; Cytochrome P-450 Enzyme System; Diethylnitrosamine; Isoenzymes; Liver | 1987 |
Expression of genes encoding glutathione S-transferases in normal and preneoplastic liver.
Topics: Animals; Gene Expression Regulation; Glutathione Transferase; Liver; Liver Neoplasms; Methylcholanth | 1987 |
Comparison of drug-metabolizing activities in the livers of carcinogen-sensitive parent rats and carcinogen-resistant descendants.
Topics: Animals; Benzopyrene Hydroxylase; Biotransformation; Cytochrome P-450 Enzyme System; Drug Resistance | 1985 |
Protein synthesis in the tumor-influenced hepatocyte.
Topics: Animals; Body Weight; Cell Division; Disease Models, Animal; Liver; Liver Neoplasms; Male; Membrane | 1985 |
Biological tests of carcinogenic activity.
Topics: Animals; Azo Compounds; Biological Assay; Carcinogens; Carcinoma, Hepatocellular; Carcinoma, Papilla | 1968 |
An attempt at biochemical characterisation of histologically well defined tumours.
Topics: Acid Phosphatase; Adenocarcinoma; Adenosine Triphosphatases; Alkaline Phosphatase; Animals; Classifi | 1966 |
Hemoproteins in microsomes in liver of tumor-bearing rats.
Topics: Animals; Carcinogens; Carcinoma, Hepatocellular; Catalase; Coloring Agents; Cytochromes; Fibrosarcom | 1965 |
Studies on leukemia in mice associated with a transplantable methylcholanthrene-induced hepatoma.
Topics: Animals; Carcinoma, Hepatocellular; Leukemia, Experimental; Leukemia, Myeloid; Liver Neoplasms; Meth | 1966 |
Induced hyperlipemia and the dissemination of tumor cells.
Topics: Animals; Carcinoma, Hepatocellular; Emulsions; Hyperlipidemias; Injections, Intravenous; Liver Neopl | 1967 |
[The cancer problem in fundamental research].
Topics: Animals; Antigens; Antineoplastic Agents; Carcinoma, Hepatocellular; Culture Techniques; Cyclophosph | 1966 |
Pressure effects on survival of mice with transplantable leukaemia.
Topics: Animals; Atmospheric Pressure; Body Weight; Carcinoma, Hepatocellular; Leukemia; Liver Neoplasms; Me | 1968 |
[Delayed type hypersensitivity in tumor-bearing rats].
Topics: Animals; Antigens; Carcinoma, Hepatocellular; Freund's Adjuvant; Hypersensitivity, Delayed; Immuniza | 1967 |
Effect of some mutagenic virogens and carcinogens on deoxyribonucleic acid.
Topics: Animals; Ascitic Fluid; Benzopyrenes; Bombyx; Carcinogens; Carcinoma, Hepatocellular; Cattle; Centri | 1968 |
Sensitivity of newborn mice to carcinogenic agents.
Topics: Adenocarcinoma; Adenoma; Animals; Animals, Newborn; Benz(a)Anthracenes; Carcinogens; Carcinoma, Hepa | 1968 |
[Experimental hematogenous metastasis of a fibrosarcoma in animals with and without spleen].
Topics: Animals; Antibody Formation; Carcinoma, Hepatocellular; Fibrosarcoma; Liver Neoplasms; Lung Neoplasm | 1969 |
Benzpyrene hydroxylase activity and its induction by methylcholanthrene in Morris hepatomas, in host livers, in adult livers, and in rat liver during development.
Topics: Animals; Benzopyrenes; Carcinoma, Hepatocellular; Cycloheximide; Dactinomycin; Enzyme Induction; Fem | 1970 |
[A new animal for experimental oncologic research--the Dzhungarian hamster].
Topics: Animals; Animals, Laboratory; Benz(a)Anthracenes; Carcinoma, Hepatocellular; Carcinoma, Squamous Cel | 1970 |
Effects of 3-methylcholanthrene pretreatment on microsomal hydroxylation of 2-acetamidofluorene by various rat hepatomas.
Topics: Animals; Carcinogens; Carcinoma, Hepatocellular; Female; Fluorenes; Kidney; Liver; Liver Neoplasms; | 1970 |
Effect of 3-methylcholanthrene on hyperplastic and early neoplastic hepatic lesions induced in rats by carbon tetrachloride.
Topics: Age Factors; Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Carcinogens; Carcinoma, | 1970 |
Experimental studies on trauma and metastasis formation.
Topics: Animals; Blood Coagulation; Carcinoma, Hepatocellular; Dextrans; Female; Fibrinolysis; Heparin; Inje | 1968 |
Enzyme patterns in a group of transplantable mouse hepatomas of different growth rates.
Topics: Animals; Carboxy-Lyases; Carcinoma, Hepatocellular; Growth; Humans; Inbreeding; Liver; Liver Neoplas | 1971 |
Demonstration of cell-surface antigens on chemically induced tumors.
Topics: Animals; Antibody Specificity; Antigens; Antigens, Neoplasm; Carcinogens; Carcinoma; Carcinoma, Hepa | 1971 |
Chemical carcinogenesis in Syrian hamsters.
Topics: Adenocarcinoma, Bronchiolo-Alveolar; Animals; Azo Compounds; Benz(a)Anthracenes; Benzopyrenes; Bronc | 1972 |
Tumour specific and embryonic antigen expression of chemically induced rat tumours.
Topics: Animals; Antigens; Antigens, Neoplasm; Carcinoma, Hepatocellular; Cell Membrane; Cytotoxicity Tests, | 1972 |
Intracisternal A-type and C-type particles observed in pulmonary tumors in mice.
Topics: Adenocarcinoma; Animals; Antigens, Viral; Ascites; Carcinoma, Hepatocellular; Culture Techniques; Fl | 1972 |
Embryonic antigen expression in chemically induced rat hepatomas and sarcomas.
Topics: Animals; Antigen-Antibody Reactions; Antigens, Neoplasm; Carcinoembryonic Antigen; Carcinoma, Hepato | 1972 |
Effect of 1-naphthyl isothiocyanate and 3-methylcholanthrene on hepatocarcinogenesis in rats treated with diethylnitrosoamine.
Topics: Animals; Bile Ducts, Intrahepatic; Body Weight; Carcinoma, Hepatocellular; Fibrosarcoma; Hemangioend | 1973 |
The induction of tumours in the guinea-pig with methylcholanthrene and diethylnitrosamine and their propagation in vivo and in vitro.
Topics: Animals; Carcinoma, Hepatocellular; Fibrosarcoma; Guinea Pigs; Liposarcoma; Liver Neoplasms; Methylc | 1973 |
Aryl hydrocarbon hydroxylase induction in mammalian liver cell culture. IV. Stimulation of the enzyme activity in established cell lines derived from rat or mouse hepatoma and from normal rat liver.
Topics: Animals; Benz(a)Anthracenes; Benzopyrenes; Carcinoma, Hepatocellular; Cell Line; Cricetinae; Culture | 1973 |
Isolation and chemical characterization of mucopolysaccharides from rat tumors.
Topics: Animals; Carcinoma, Hepatocellular; Chondroitin; Chromatography, Ion Exchange; Electrophoresis; Gluc | 1974 |
Neoplasms and amyloidosis in strains of mice treated with 3-methylcholanthrene.
Topics: Adenoma; Amyloidosis; Animals; Carcinoma, Hepatocellular; Carcinoma, Squamous Cell; Female; Liver Ne | 1974 |
Influence of age and 3-methylcholanthrene on azo-dye carcinogenesis and metabolism of p-dimethylaminoazobenzene in rat liver.
Topics: Age Factors; Animals; Azo Compounds; Carcinoma, Hepatocellular; DNA; Liver; Liver Neoplasms; Male; M | 1973 |
Radiation-killed BCG in the treatment of transplanted rat tumours.
Topics: Animals; Azo Compounds; BCG Vaccine; Benzene Derivatives; Carcinoma, Hepatocellular; Cell Survival; | 1974 |
A preliminary investigation into the role of immunity in modifying the blood- borne spread of chemically induced rat sarcomas.
Topics: Animals; Benzopyrenes; Carcinogens; Carcinoma, Hepatocellular; Ethionine; Graft Rejection; Immunizat | 1974 |
[Natural carcinogens: summation effects of carcinogens].
Topics: Amines; Animals; Carcinogens; Drug Interactions; Liver Neoplasms; Male; Methylcholanthrene; Naphthal | 1972 |
Dose-response and ultrastructural alterations in dioxane carcinogenesis. Influence of methylcholanthrene on acute toxicity.
Topics: Animals; Carcinogens; Dioxins; Dose-Response Relationship, Drug; Enzyme Induction; Lethal Dose 50; L | 1973 |
Frequency and organ distribution of lung tumor metastases in CF-1 mice.
Topics: Animals; Carcinoma; Female; Heart Neoplasms; Kidney; Kidney Neoplasms; Liver; Liver Neoplasms; Lung | 1974 |
Influence of 3-methylcholanthrene on liver carcinogenesis in rats ingesting DL-ethionine, 3'-methyl-4-dimethylaminoazobenzene, and N-2-fluorenylacetamide.
Topics: Amides; Animals; Carcinogens; Ethionine; Fluorenes; Liver; Liver Neoplasms; Male; Methylcholanthrene | 1967 |
Effect of barbital on carcinogenic action and metabolism of 4-dimethylaminoazobenzene.
Topics: Aminobenzoates; Animals; Barbiturates; Bile; Glucuronates; Liver; Liver Neoplasms; Lung Neoplasms; M | 1967 |
Preferential binding of 2-acetylaminofluorene to rat liver rRNA during early stages of hepatocarcinogenesis.
Topics: Acetamides; Animals; Binding Sites; Carbon Isotopes; Carcinogens; Female; Fluorenes; Liver; Liver Ne | 1972 |
Studies on the effect of methoxy-substituted glycerol ethers on tumour growth and metastasis formation.
Topics: Administration, Oral; Animals; Body Weight; Ethers; Female; Glycerol; Injections, Intraperitoneal; I | 1971 |
Influence of 3-methylcholanthrene and diet on the binding of 2-acetylaminofluroene and its N-hydroxy metabolite to rat liver nucleic acids.
Topics: Acetates; Amides; Animals; Carbon Isotopes; Depression, Chemical; Diet; DNA; Drug Antagonism; Ear Ne | 1971 |
Evidence of antitumorigenic effects of DDT.
Topics: Animals; DDT; Diet; Enzyme Induction; Ependymoma; Liver; Liver Neoplasms; Male; Methylcholanthrene; | 1971 |
Labeling in vivo of rat liver proteins by tritium-labeled dimethylnitrosamine. Effect of prior treatment with 3-methylcholanthrene, phenobarbitone, dimethylformamide, diethyl-formamide, aminoacetonitrile, ethionine and carbon tetrachloride.
Topics: Amides; Animals; Carbon Tetrachloride; Carcinogens; Dimethylformamide; Endoplasmic Reticulum; Ethion | 1971 |
[Morphologic behavior of a fibrosarcoma following transplantation into various organs].
Topics: Animals; Cell Transformation, Neoplastic; Female; Fibrosarcoma; Glioma; Kidney Neoplasms; Liver Neop | 1970 |
Analysis of cell-mediated immune reactions to syngeneic mouse tumors in tissue culture.
Topics: Animals; Antineoplastic Agents; Ascitic Fluid; Chromium Isotopes; Culture Techniques; Female; Immune | 1969 |
[The effect of iron-dextran and ironfree colloid on the distribution of experimental metastases].
Topics: Animals; Antineoplastic Agents; Iron-Dextran Complex; Liver Neoplasms; Lung Neoplasms; Methylcholant | 1970 |
Effect of immune status on the development of artificially induced metastases in different anatomical locations.
Topics: Animals; Immune Tolerance; Injections, Intraperitoneal; Injections, Subcutaneous; Liver Neoplasms; L | 1971 |
Combined carcinogenic effects of dimethylnitrosamine and 3-methylcholanthrene in the rat.
Topics: Animals; Drug Synergism; Liver Neoplasms; Lung Neoplasms; Methylcholanthrene; Neoplasms, Experimenta | 1968 |
A study of soluble protein and sulfhydryl levels in the rat liver during rapid normal and premalignant growth.
Topics: Animals; Carcinogens; Electrophoresis; Growth; Hepatectomy; Liver; Liver Neoplasms; Male; Methylchol | 1968 |
Carcinogenicity in the hamster of simultaneously administered 2-acetamidofluorene and 3-methylcholanthrene.
Topics: Adenoma; Animals; Bile Duct Neoplasms; Body Weight; Carcinoma; Cricetinae; Fluorenes; Liver; Liver N | 1968 |
The development of carcinoma in liver of rats treated with m-toluylenediamine and the synergistic and antagonistic effects with other chemicals.
Topics: Aniline Compounds; Animals; Diet; Drug Antagonism; Drug Synergism; Ethionine; Liver Neoplasms; Male; | 1969 |
A spontaneously metastasizing 20-methylcholanthrene-induced rhabdomyosarcoma and its transformation to ascites form in the CBA mouse.
Topics: Animals; Carcinogens; Chromosome Aberrations; Chromosome Disorders; Female; Injections, Intraperiton | 1966 |
Effect of heparin and plasminogen inhibitor (EACA) in brief and prolonged treatment on intravenously injected tumour cells.
Topics: Aminocaproates; Animals; Heparin; Liver Neoplasms; Lung Neoplasms; Methylcholanthrene; Mice; Neoplas | 1966 |