3-methylcholanthrene has been researched along with Kidney Diseases in 5 studies
Methylcholanthrene: A carcinogen that is often used in experimental cancer studies.
3-methylcholanthrene : A pentacyclic ortho- and peri-fused polycyclic arene consisting of a dihydrocyclopenta[ij]tetraphene ring system with a methyl substituent at the 3-position.
Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| " These results indicate that hepatic P450s play an important role in metabolizing aristolochic acid I into less toxic metabolites and thus have a detoxification role in aristolochic acid I-induced kidney injury." | 1.35 | Hepatic cytochrome P450s metabolize aristolochic acid and reduce its kidney toxicity. ( Ge, M; Gu, J; Li, L; Li, Y; Liu, L; Luo, H; Qi, X; Ren, J; Wang, C; Wang, H; Wu, X; Xiao, Y; Xie, T; Xue, X; Zhang, Y, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (80.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xiao, Y | 1 |
| Ge, M | 1 |
| Xue, X | 1 |
| Wang, C | 1 |
| Wang, H | 1 |
| Wu, X | 1 |
| Li, L | 1 |
| Liu, L | 1 |
| Qi, X | 1 |
| Zhang, Y | 1 |
| Li, Y | 1 |
| Luo, H | 1 |
| Xie, T | 1 |
| Gu, J | 1 |
| Ren, J | 1 |
| Sesardic, D | 1 |
| Rich, KJ | 1 |
| Edwards, RJ | 1 |
| Davies, DS | 1 |
| Boobis, AR | 1 |
| Burke, MD | 1 |
| Whiting, PH | 1 |
| Klockars, M | 1 |
| Azar, HA | 1 |
| Hermida, R | 1 |
| Isobe, T | 1 |
| Hsu, CC | 1 |
| Ansari, H | 1 |
| Osserman, EF | 1 |
| Reid, WD | 1 |
| Ilett, KF | 1 |
| Glick, JM | 1 |
| Krishna, G | 1 |
5 other studies available for 3-methylcholanthrene and Kidney Diseases
| Article | Year |
|---|---|
Hepatic cytochrome P450s metabolize aristolochic acid and reduce its kidney toxicity.
Topics: Animals; Aristolochic Acids; Carcinogens; Cell Fractionation; Inactivation, Metabolic; Kidney Diseas | 2008 |
Selective destruction of cytochrome P-450d and associated monooxygenase activity by carbon tetrachloride in the rat.
Topics: Animals; Blotting, Western; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; | 1989 |
The role of drug metabolism in cyclosporine A nephrotoxicity.
Topics: Aminopyrine N-Demethylase; Animals; Cyclosporins; Cytochrome P-450 Enzyme System; Enzyme Induction; | 1986 |
The relationship of lysozyme to the nephropathy in chloroleukemic rats and the effects of lysozyme loading on normal rat kidneys.
Topics: Animals; Antibodies; Antigen-Antibody Reactions; Blood Protein Electrophoresis; Cytoplasm; Electroph | 1974 |
Metabolism and binding of aromatic hydrocarbons in the lung. Relationship to experimental bronchiolar necrosis.
Topics: Animals; Autoradiography; Bromine; Bronchial Diseases; Carbon Isotopes; Chemical and Drug Induced Li | 1973 |