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3-methylcholanthrene and Inflammation

3-methylcholanthrene has been researched along with Inflammation in 20 studies

Methylcholanthrene: A carcinogen that is often used in experimental cancer studies.
3-methylcholanthrene : A pentacyclic ortho- and peri-fused polycyclic arene consisting of a dihydrocyclopenta[ij]tetraphene ring system with a methyl substituent at the 3-position.

Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.

Research Excerpts

ExcerptRelevanceReference
"1 To investigate the effect of moderate hypoxia alone or combined with an inflammatory reaction or after 3-methylcholanthrene (3MC) pre-treatment on cytochrome P450 (P450), conscious rabbits were exposed for 24 h to a fractional concentration of inspired O2 of 10% (mean PaO2 of 34 mmHg)."7.70Effect of hypoxia alone or combined with inflammation and 3-methylcholanthrene on hepatic cytochrome P450 in conscious rabbits. ( Bélanger, PM; Dalkara, S; El-Kadi, AO; Kurdi, J; Maurice, H; Ong, H; Souich, P, 1999)
"1 To investigate the effect of moderate hypoxia alone or combined with an inflammatory reaction or after 3-methylcholanthrene (3MC) pre-treatment on cytochrome P450 (P450), conscious rabbits were exposed for 24 h to a fractional concentration of inspired O2 of 10% (mean PaO2 of 34 mmHg)."3.70Effect of hypoxia alone or combined with inflammation and 3-methylcholanthrene on hepatic cytochrome P450 in conscious rabbits. ( Bélanger, PM; Dalkara, S; El-Kadi, AO; Kurdi, J; Maurice, H; Ong, H; Souich, P, 1999)
"Infection and inflammation are known to affect the metabolism and disposition of drugs and carcinogens."1.27Potentiation and suppression of mouse liver cytochrome P-450 isozymes during the acute-phase response induced by bacterial endotoxin. ( Adams, DJ; Liao, W; Lindsay, R; Meehan, RR; Stanley, LA; Wolf, CR, 1988)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-199012 (60.00)18.7374
1990's1 (5.00)18.2507
2000's4 (20.00)29.6817
2010's3 (15.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Onuma, K1
Suenaga, Y1
Sakaki, R1
Yoshitome, S1
Sato, Y1
Ogawara, S1
Suzuki, S1
Kuramitsu, Y1
Yokoyama, H1
Murakami, A1
Hamada, J1
Nicolson, GL1
Kobayashi, M1
Fujii, J1
Okada, F1
Sharma, A1
Saurabh, K1
Yadav, S1
Jain, SK1
Parmar, D1
Ruud, J1
Wilhelms, DB1
Nilsson, A1
Eskilsson, A1
Tang, YJ1
Ströhle, P1
Caesar, R1
Schwaninger, M1
Wunderlich, T1
Bäckhed, F1
Engblom, D1
Blomqvist, A1
STEWART, HL1
SNELL, KC1
MORRIS, HP1
Apte, RN2
Krelin, Y2
Song, X1
Dotan, S2
Recih, E1
Elkabets, M2
Carmi, Y1
Dvorkin, T1
White, RM1
Gayvoronsky, L1
Segal, S2
Voronov, E2
Reich, E1
Fogel, M1
Huszar, M1
Iwakura, Y1
Dinarello, CA1
Chiarella, P1
Vulcano, M1
Laborde, E1
Vermeulen, M1
Bruzzo, J1
Rearte, B1
Bustuoabad, OD1
Ruggiero, RA1
Swann, JB1
Vesely, MD1
Silva, A1
Sharkey, J1
Akira, S1
Schreiber, RD1
Smyth, MJ1
Normann, SJ1
Schardt, MC1
Sorkin, E2
Kurdi, J1
Maurice, H1
El-Kadi, AO1
Ong, H1
Dalkara, S1
Bélanger, PM1
Souich, P1
Gershbein, LL1
Benuck, I1
Normann, S1
Schardt, M1
Stanley, LA1
Adams, DJ1
Lindsay, R1
Meehan, RR1
Liao, W1
Wolf, CR1
Hashimoto, T1
Burstone, MS1
Cooper, EL1
Thomas, PE1
Kouri, RE1
Hutton, JJ1
Kearney, R1
Nelson, DS1
Scribner, JD1
Slaga, TJ1
Lappé, MA1
Feit, J1
Buscher, H1
Oehlert, W1

Reviews

1 review available for 3-methylcholanthrene and Inflammation

ArticleYear
Effects of micro-environment- and malignant cell-derived interleukin-1 in carcinogenesis, tumour invasiveness and tumour-host interactions.
    European journal of cancer (Oxford, England : 1990), 2006, Volume: 42, Issue:6

    Topics: Animals; Carcinogens; Humans; Inflammation; Interleukin-1; Methylcholanthrene; Mice; Models, Biologi

2006

Other Studies

19 other studies available for 3-methylcholanthrene and Inflammation

ArticleYear
Development of a quantitative bioassay to assess preventive compounds against inflammation-based carcinogenesis.
    Nitric oxide : biology and chemistry, 2011, Aug-01, Volume: 25, Issue:2

    Topics: Animals; Anticarcinogenic Agents; Biological Assay; Cell Adhesion; Coumarins; Endothelial Cells; Fem

2011
Expression profiling of selected genes of toxication and detoxication pathways in peripheral blood lymphocytes as a biomarker for predicting toxicity of environmental chemicals.
    International journal of hygiene and environmental health, 2013, Volume: 216, Issue:6

    Topics: Animals; Apoptosis; Biomarkers; Cytochrome P-450 Enzyme System; Environmental Exposure; Environmenta

2013
Inflammation- and tumor-induced anorexia and weight loss require MyD88 in hematopoietic/myeloid cells but not in brain endothelial or neural cells.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2013, Volume: 27, Issue:5

    Topics: Animals; Anorexia; Brain; Cachexia; Chimera; Endothelial Cells; Inflammation; Methylcholanthrene; Mi

2013
(THE COMBINED EFFECT OF 3-METHYLCHOLANTHRENE AND N,N'-2,7-FLUORENYLENEBISACETMIDE ON THE INDUCTION OF CANCER OF THE GLANDULAR STOMACH OF THE RAT.)
    Journal of the National Cancer Institute, 1965, Volume: 34

    Topics: Abdominal Neoplasms; Abdominal Wall; Atrophy; Carcinogens; Ethmoid Bone; Female; Humans; Inflammatio

1965
Interleukin-1beta-driven inflammation promotes the development and invasiveness of chemical carcinogen-induced tumors.
    Cancer research, 2007, Feb-01, Volume: 67, Issue:3

    Topics: Animals; Carcinogens; Cocarcinogenesis; Female; Fibrosarcoma; Inflammation; Interleukin 1 Receptor A

2007
[Reversion of the immunological eclipse and therapeutic vaccination against cancer in an experimental model].
    Medicina, 2007, Volume: 67, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Cancer Vaccines; Carcinogens; Dendritic Cells; Dexamethasone; Dis

2007
Demonstration of inflammation-induced cancer and cancer immunoediting during primary tumorigenesis.
    Proceedings of the National Academy of Sciences of the United States of America, 2008, Jan-15, Volume: 105, Issue:2

    Topics: Animals; Cell Line, Tumor; Fibrosarcoma; Gene Expression Regulation, Neoplastic; Immune System; Infl

2008
Macrophage inflammatory responses in rats and mice with autochthonous and transplanted tumors induced by 3-methylcholanthrene.
    Journal of the National Cancer Institute, 1984, Volume: 72, Issue:1

    Topics: Animals; Inflammation; Macrophages; Methylcholanthrene; Mice; Mice, Inbred C57BL; Neoplasm Transplan

1984
Effect of hypoxia alone or combined with inflammation and 3-methylcholanthrene on hepatic cytochrome P450 in conscious rabbits.
    British journal of pharmacology, 1999, Volume: 128, Issue:2

    Topics: Animals; Apoproteins; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP1A1; Cyto

1999
Cortical implantation of hydrocarbons in rats and mice.
    Oncology, 1975, Volume: 31, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Brain Diseases; Brain Neoplasms; Carc

1975
Cancer induced anti-inflammation and its potentiation by tumor excision and rechallenge.
    Journal of leukocyte biology, 1987, Volume: 42, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Neoplasm; Corticosterone; Fibrosarcoma; Granulo

1987
Potentiation and suppression of mouse liver cytochrome P-450 isozymes during the acute-phase response induced by bacterial endotoxin.
    European journal of biochemistry, 1988, May-16, Volume: 174, Issue:1

    Topics: Acute-Phase Reaction; Animals; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; E

1988
Distribution patterns of oxidative enzymes in experimentally induced tumors, regeneration and inflammation of mouse skin.
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 1966, Volume: 14, Issue:1

    Topics: Animals; Burns; Carcinoma, Squamous Cell; Citric Acid Cycle; Electron Transport Complex IV; Glucosep

1966
Neoplasia and transplantation immunity in annelids.
    National Cancer Institute monograph, 1969, Volume: 31

    Topics: Animals; Annelida; Granuloma; Histocompatibility; Inflammation; Methylcholanthrene; Neoplasm Transpl

1969
The genetics of aryl hydrocarbon hydroxylase induction in mice: a single gene difference between C57BL-6J and DBA-2J.
    Biochemical genetics, 1972, Volume: 6, Issue:2

    Topics: Alleles; Animals; Benz(a)Anthracenes; Benzopyrenes; Crosses, Genetic; Female; Genetic Linkage; Hybri

1972
Concomitant immunity to syngeneic methylcholanthrene-induced tumours in mice. Occurrence and specificity of concomitant immunity.
    The Australian journal of experimental biology and medical science, 1973, Volume: 51, Issue:6

    Topics: Animals; Antibody Specificity; Female; Foot; Freund's Adjuvant; Hindlimb; Immunity; Inflammation; In

1973
Influence of nonsteroid anti-inflammatory agents on protein synthesis and hyperplasia caused by a tumor promoter.
    Journal of the National Cancer Institute, 1974, Volume: 52, Issue:6

    Topics: Acetates; Alcohols; Animals; Anti-Inflammatory Agents; Carcinogens; Cytosol; Diterpenes; Fatty Acids

1974
Evidence for immunological surveillance during skin carcinogenesis. Inflammatory foci in immunologically competent mice.
    Israel journal of medical sciences, 1971, Volume: 7, Issue:1

    Topics: Animals; Antilymphocyte Serum; Inflammation; Methylcholanthrene; Mice; Neoplasm Transplantation; Neo

1971
[The distribution pattern and the length of stay of radioactively labeled carcinogenic hydrocarbons in the pigskin].
    Beitrage zur pathologischen Anatomie und zur allgemeinen Pathologie, 1967, Volume: 136, Issue:1

    Topics: Animals; Autoradiography; Benz(a)Anthracenes; Benzopyrenes; Cell Nucleus; Cytoplasm; Dimethyl Sulfox

1967