3-methylcholanthrene has been researched along with Hepatocellular Carcinoma in 86 studies
Methylcholanthrene: A carcinogen that is often used in experimental cancer studies.
3-methylcholanthrene : A pentacyclic ortho- and peri-fused polycyclic arene consisting of a dihydrocyclopenta[ij]tetraphene ring system with a methyl substituent at the 3-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The animal models were Sewall Wright strain 13 guinea pigs with 3-methyl-cholanthrene (MCA)-induced fibrosarcomas and strain 2 guinea pigs with diethylnitrosamine (DEN)-induced hepatocarcinomas." | 3.66 | Guinea pig cell-mediated tumor immunity: the chromium release assay detects both cytolysis and serum blocking for syngeneic chemically-induced tumors. ( Blazkovec, AA; Miller, FR, 1979) |
| "The characteristic clostridial growth which is testable, after systemic administration of tetanus spores, as a positive tumour tetanus - correlation, was manifested by a highly selective tetanus lethality of rats with progressive hepatomas following induction with dimethylaminoazobenzene and diethylnitrosamine, respectively, as well as with methylcholanthren-induced fibrosarcomas of the rat." | 3.65 | [The tumor-tetanus assay--experimental studies on the biological differentiation between carcinogenesis and organ regeneration of the rat (author's transl)]. ( Fabricius, EA; Schneeweiss, U, 1975) |
| "As a subject of inquiry the hepatoma cell cultures HepG2 expressed Ah receptor and G27 not expressed Ah receptor were used." | 1.37 | [Activation of transcription factor NF-kappaB by carcinogenic polycyclic aromatic hydricarbons]. ( Kobliakov, VA; Volkov, MS, 2011) |
| " Further study demonstrated that UGT1A1 mRNA expression could be induced in human hepatocyte cultures by either increasing the chrysin dosing frequency or by modulating chrysin metabolism, suggesting that the differential induction observed in hepatocytes and HepG2 cells was due to differences in the metabolic clearance of chrysin." | 1.33 | Differential UGT1A1 induction by chrysin in primary human hepatocytes and HepG2 Cells. ( Graham, RA; Krol, WL; Lecluyse, EL; Negishi, M; Silver, IS; Smith, CM; Wang, H, 2005) |
| "When murine hepatoma cell line Hepa-1c1c7 was stably transfected with this construct, established sensor clones secreted SEAP following stimulation with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)." | 1.32 | DRESSA: biosensing of dioxin and dioxin-like chemicals using secreted alkaline phosphatase. ( Hiramatsu, N; Kasai, A; Kitamura, M; Maeda, S; Meng, Y; Takeda, M; Yao, J, 2004) |
| " The expression of ALDH3A1 in HepG2 cells showed typical time- and dose-response curves of induction after application of 3MC (1-5 days, 1." | 1.31 | Effects of 3-methylcholanthrene and aspirin co-administration on ALDH3A1 in HepG2 cells. ( Marselos, M; Pappas, P; Sotiropoulou, M, 2001) |
| " In an effort better to understand factors that may affect the oral bioavailability of the bioflavonoids from dietary sources, the metabolism of chrysin by cultured intestinal Caco-2 cells and hepatic Hep G2 cells was studied, together modelling human presystemic metabolism." | 1.30 | Extensive metabolism of the flavonoid chrysin by human Caco-2 and Hep G2 cells. ( Galijatovic, A; Otake, Y; Walle, T; Walle, UK, 1999) |
| "(3) A human hepatoma cell line (Hep G2) was studied to obtain information on the inducibility of human UDP-GT activities by 3-methylcholanthrene-type inducers." | 1.27 | Differential induction of human liver UDP-glucuronosyltransferase activities by phenobarbital-type inducers. ( Bock, KW; Bock-Hennig, BS, 1987) |
| "It is concluded, that HepG2 hepatoma cells behave similar to the normal hepatocytes in terms of ALDH regulation and can be used for studies on the activity of ALDH as modified by added xenobiotics." | 1.27 | Effect of phenobarbital and 3-methylcholanthrene on aldehyde dehydrogenase activity in cultures of HepG2 cells and normal human hepatocytes. ( Marselos, M; Michalopoulos, G; Strom, SC, 1987) |
| "In well differentiated, slowly growing hepatomas, the concentration of GSH approached the level in normal adult rat liver." | 1.26 | Glutathione and gamma glutamyl transpeptidase in rat liver during chemical carcinogenesis. ( Fiala, AE; Fiala, S; Kettering, WG; Mohindru, A; Morris, HP, 1976) |
| "These neoplasms included cholangiomas, hepatoadenomas, cholangiocarcinomas, and hepatocellular cancers." | 1.25 | Tumor induction by carcinogenic agents in aquarium fish. ( Khudoley, VV; Pliss, GB, 1975) |
| "DNA synthesis in a transplanted hepatoma induced by 3'-methyl-4-dimethylaminoazobenzene was significantly reduced (P less than 0." | 1.25 | Zinc intake, neoplastic DNA synthesis, and chemical carcinogenesis in rats and mice. ( Dreosti, IE; Duncan, JR, 1975) |
| "2." | 1.25 | Effects of 3-methylcholanthrene pretreatment on microsomal hydroxylation of 2-acetamidofluorene by various rat hepatomas. ( Lotlikar, PD, 1970) |
| "The hepatomata are all predominantly hepatocellular carcinomata and the sarcomata comprise two liposarcomata and a fibrosarcoma." | 1.25 | The induction of tumours in the guinea-pig with methylcholanthrene and diethylnitrosamine and their propagation in vivo and in vitro. ( Andjargholi, M; Dale, MM; Desai, H; Easty, GC; Tchao, R, 1973) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 60 (69.77) | 18.7374 |
| 1990's | 10 (11.63) | 18.2507 |
| 2000's | 12 (13.95) | 29.6817 |
| 2010's | 4 (4.65) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Utgikar, R | 1 |
| Riddick, DS | 2 |
| Kim, HG | 1 |
| Han, EH | 1 |
| Im, JH | 1 |
| Lee, EJ | 1 |
| Jin, SW | 1 |
| Jeong, HG | 1 |
| Hosaka, T | 1 |
| Sekimoto, M | 1 |
| Nemoto, K | 1 |
| Degawa, M | 1 |
| Volkov, MS | 1 |
| Kobliakov, VA | 1 |
| ODASHIMA, S | 1 |
| KLEIN, M | 2 |
| MAISIN, J | 1 |
| USUBUCHI, I | 1 |
| CONNEY, AH | 1 |
| BURNS, JJ | 1 |
| POTTER, VR | 2 |
| KIKUCHI, K | 1 |
| TSUJI, Y | 1 |
| ITAKURA, K | 1 |
| KATAGIRI, H | 1 |
| Kasai, A | 1 |
| Hiramatsu, N | 1 |
| Meng, Y | 1 |
| Yao, J | 1 |
| Takeda, M | 1 |
| Maeda, S | 1 |
| Kitamura, M | 1 |
| Elbekai, RH | 1 |
| Korashy, HM | 1 |
| Wills, K | 1 |
| Gharavi, N | 1 |
| El-Kadi, AO | 1 |
| Finel, M | 1 |
| Li, X | 1 |
| Gardner-Stephen, D | 1 |
| Bratton, S | 1 |
| Mackenzie, PI | 1 |
| Radominska-Pandya, A | 1 |
| Smith, CM | 1 |
| Graham, RA | 1 |
| Krol, WL | 1 |
| Silver, IS | 1 |
| Negishi, M | 1 |
| Wang, H | 1 |
| Lecluyse, EL | 1 |
| Sawaya, RM | 1 |
| Lambiotte, M | 1 |
| Thierry, N | 1 |
| Quattrochi, LC | 1 |
| Vu, T | 1 |
| Tukey, RH | 1 |
| Rosenberg, DW | 1 |
| Leff, T | 1 |
| Xu, LC | 1 |
| Sinclair, PR | 1 |
| Bresnick, E | 2 |
| Nicod, L | 1 |
| Viollon, C | 1 |
| Regnier, A | 1 |
| Jacqueson, A | 1 |
| Richert, L | 1 |
| Ainbinder, E | 1 |
| Bergelson, S | 1 |
| Daniel, V | 1 |
| Galijatovic, A | 1 |
| Otake, Y | 1 |
| Walle, UK | 1 |
| Walle, T | 1 |
| Ledirac, N | 1 |
| Delescluse, C | 1 |
| Lesca, P | 1 |
| Piechocki, MP | 1 |
| Hines, RN | 1 |
| de Sousa, G | 1 |
| Pralavorio, M | 1 |
| Rahmani, R | 1 |
| Chen, RM | 1 |
| Chou, MW | 1 |
| Ueng, TH | 1 |
| Mathieu, MC | 1 |
| Lapierre, I | 1 |
| Brault, K | 1 |
| Raymond, M | 1 |
| Sotiropoulou, M | 1 |
| Pappas, P | 1 |
| Marselos, M | 2 |
| Guigal, N | 1 |
| Seree, E | 1 |
| Nguyen, QB | 1 |
| Charvet, B | 1 |
| Desobry, A | 1 |
| Barra, Y | 1 |
| Leung, YK | 1 |
| Ho, JW | 1 |
| Oh, SM | 1 |
| Kim, KR | 1 |
| Ro, KS | 1 |
| Chung, KH | 1 |
| Watanabe, M | 3 |
| Konno, K | 2 |
| Sato, H | 2 |
| Fiala, S | 1 |
| Mohindru, A | 1 |
| Kettering, WG | 1 |
| Fiala, AE | 1 |
| Morris, HP | 3 |
| Pimm, MV | 4 |
| Baldwin, RW | 8 |
| Schneeweiss, U | 1 |
| Fabricius, EA | 1 |
| Pliss, GB | 1 |
| Khudoley, VV | 1 |
| Duncan, JR | 1 |
| Dreosti, IE | 1 |
| Sakamoto, M | 1 |
| Nishioka, K | 1 |
| Zöller, M | 1 |
| Price, MR | 2 |
| Williams, MT | 1 |
| Gaylor, JL | 1 |
| Kovalszky, I | 1 |
| Jeney, A | 1 |
| Asbót, R | 1 |
| Lapis, K | 1 |
| Yumura, M | 1 |
| Matsushima, T | 1 |
| Sugimura, T | 2 |
| Brooks, CG | 1 |
| Rees, RC | 1 |
| Gessner, T | 1 |
| Kjartansson, I | 1 |
| Miller, FR | 1 |
| Blazkovec, AA | 1 |
| Dennick, RG | 1 |
| Law, LW | 1 |
| Belisario, MA | 1 |
| Arena, AR | 1 |
| Pecce, R | 1 |
| Borgia, R | 1 |
| Staiano, N | 1 |
| De Lorenzo, F | 1 |
| Visser, O | 1 |
| van den Berg, JW | 1 |
| Koole-Lesuis, H | 1 |
| Voortman, G | 1 |
| Wilson, JH | 1 |
| Fandrey, J | 1 |
| Seydel, FP | 1 |
| Siegers, CP | 1 |
| Jelkmann, W | 1 |
| Wiebel, FJ | 1 |
| Cikryt, P | 1 |
| Iwasa, F | 1 |
| Sassa, S | 1 |
| Kappas, A | 1 |
| Bock, KW | 1 |
| Bock-Hennig, BS | 1 |
| Strom, SC | 1 |
| Michalopoulos, G | 1 |
| Shimkin, MB | 1 |
| Ikeda, K | 1 |
| Hozumi, M | 1 |
| Dmochowski, L | 1 |
| Rogers, T | 1 |
| Liebelt, AG | 2 |
| Liebelt, RA | 3 |
| Sykes, JA | 1 |
| Peterson, HI | 1 |
| Rudenstam, CM | 3 |
| Schindler, R | 1 |
| Doerner, KF | 1 |
| Sanford, S | 1 |
| Sobbe, A | 1 |
| Haferkamp, O | 1 |
| Yamafuji, K | 1 |
| Uchida, Y | 1 |
| Roe, FJ | 1 |
| Walters, MA | 1 |
| Krüger, G | 1 |
| Pogosiants, EE | 1 |
| Sokova, OI | 1 |
| Prigozhina, EL | 1 |
| Lotlikar, PD | 1 |
| Reuber, MD | 1 |
| Mayfield, ED | 1 |
| Kondrat'eva, AF | 1 |
| Barker, CR | 1 |
| Embleton, MJ | 1 |
| Glaves, D | 3 |
| Moore, M | 1 |
| Vose, BM | 2 |
| Kimura, I | 1 |
| Miyake, T | 1 |
| Ishimoto, A | 1 |
| Ito, Y | 1 |
| Makiura, S | 1 |
| Kamamoto, Y | 1 |
| Sugihara, S | 1 |
| Hirao, K | 1 |
| Hiasa, Y | 1 |
| Dale, MM | 1 |
| Easty, GC | 1 |
| Tchao, R | 1 |
| Desai, H | 1 |
| Andjargholi, M | 1 |
| Benedict, WF | 1 |
| Gielen, JE | 1 |
| Owens, IS | 1 |
| Niwa, A | 1 |
| Bebert, DW | 1 |
| Kuroda, J | 1 |
| Saito, S | 1 |
| Seno, N | 1 |
| Nagase, S | 1 |
| Anno, K | 1 |
| Akamatsu, Y | 1 |
| Barton, BP | 1 |
| Decloitre, F | 1 |
| Chauveau, J | 1 |
| Martin, M | 1 |
| Cook, AJ | 1 |
| Hopper, DG | 1 |
| Proctor, JW | 1 |
| Alexander, P | 1 |
3 reviews available for 3-methylcholanthrene and Hepatocellular Carcinoma
| Article | Year |
|---|---|
Experimental carcinogenesis in small aquarium fishes.
Topics: 2-Acetylaminofluorene; Adenoma; Adenoma, Bile Duct; Aflatoxins; Animals; Benzopyrenes; Carcinogens; | 1976 |
Immunological aspects of chemical carcinogenesis.
Topics: Animals; Antibody Formation; Antigens, Neoplasm; Antilymphocyte Serum; Azo Compounds; Benz(a)Anthrac | 1973 |
[The combined action of ionizing radiation and carcinogens].
Topics: Animals; Benz(a)Anthracenes; Bone Neoplasms; Carbon Tetrachloride Poisoning; Carcinogens; Carcinoma, | 1969 |
83 other studies available for 3-methylcholanthrene and Hepatocellular Carcinoma
| Article | Year |
|---|---|
Downregulation of cytochrome P450 2C8 by 3-methylcholanthrene in human hepatocellular carcinoma cell lines.
Topics: Carcinoma, Hepatocellular; Cytochrome P-450 CYP2C8; Down-Regulation; Hep G2 Cells; Humans; Liver Neo | 2017 |
Caffeic acid phenethyl ester inhibits 3-MC-induced CYP1A1 expression through induction of hypoxia-inducible factor-1α.
Topics: Animals; Apoptosis; Caffeic Acids; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Cytoc | 2015 |
Augmentation of 3-methylcholanthrene-induced bioactivation in the human hepatoma cell line HepG2 by the calcium channel blocker nicardipine.
Topics: Aryl Hydrocarbon Hydroxylases; Calcium Channel Blockers; Carcinoma, Hepatocellular; Cell Line, Tumor | 2010 |
[Activation of transcription factor NF-kappaB by carcinogenic polycyclic aromatic hydricarbons].
Topics: Actins; Animals; Benzo(a)pyrene; Carcinogens; Carcinoma, Hepatocellular; Cell Line, Tumor; Genes, Re | 2011 |
Effect of p-(naphthol-2-azo-1) benzoxyethyl bis (beta-chloroethyl) amine on the methylcholanthrene tumors in mice and azo-dye hepatoma in rats.
Topics: Amines; Animals; Carcinoma, Hepatocellular; Liver Neoplasms; Mechlorethamine; Methylcholanthrene; Mi | 1956 |
SUSCEPTIBILITY OF STRAIN B6AF1-J HYBRID INFANT MICE TO TUMORIGENESIS WITH 1,2-BENZANTHRACENE, DEOXYCHOLIC ACID, AND 3-METHYLCHOLANTHRENE.
Topics: Animals; Animals, Newborn; Benz(a)Anthracenes; Bile Acids and Salts; Carcinogenesis; Carcinogens; Ca | 1963 |
[ATTEMPTED IMMUNOPROPHYLAXIS OF EXPERIMENTALLY INDUCED CANCERS].
Topics: Animals; Carcinoma, Hepatocellular; Immunization; Liver Neoplasms; Methylcholanthrene; Mice; Neoplas | 1964 |
ADMINISTRATION METHOD OF MITOMYCIN C.
Topics: Carcinoma, Hepatocellular; Liver Neoplasms; Methylcholanthrene; Mitomycin; Mitomycins; Neoplasms; Ne | 1964 |
INDUCED SYNTHESIS OF OXIDATIVE ENZYMES IN LIVER MICROSOMES BY POLYCYCLIC HYDROCARBONS AND DRUGS.
Topics: Aminopyrine; Androgens; Benzopyrenes; Carbohydrate Metabolism; Carcinoma, Hepatocellular; Ethionine; | 1963 |
BIOCHEMISTRY OF REGULATION OF ENZYME ACTIVITY AND SYNTHESIS. SESSION CHAIRMAN'S COMMENTS.
Topics: Adenosine Triphosphate; Biochemistry; Carcinoma, Hepatocellular; Feedback; Liver; Liver Neoplasms; M | 1963 |
A CASE OF METASTASES OF GASTRIC CANCER TO HYPERNEPHROMA AND ITS METASTATIC FOCI.
Topics: Adenocarcinoma; Carcinoma, Hepatocellular; Carcinoma, Renal Cell; Kidney Neoplasms; Liver Neoplasms; | 1964 |
Development of hepatomas in inbred albino mice following treatment with 20-methylcholanthrene.
Topics: Animals; Carcinoma, Hepatocellular; Liver Neoplasms; Liver Neoplasms, Experimental; Methylcholanthre | 1959 |
DRESSA: biosensing of dioxin and dioxin-like chemicals using secreted alkaline phosphatase.
Topics: Alkaline Phosphatase; Animals; Benzo(a)pyrene; beta-Naphthoflavone; Carcinoma, Hepatocellular; Cytoc | 2004 |
Benzo[a]pyrene, 3-methylcholanthrene and beta-naphthoflavone induce oxidative stress in hepatoma hepa 1c1c7 Cells by an AHR-dependent pathway.
Topics: Benzo(a)pyrene; beta-Naphthoflavone; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Cyt | 2004 |
Human UDP-glucuronosyltransferase 1A5: identification, expression, and activity.
Topics: Adult; Aged; Amino Acid Sequence; Animals; Baculoviridae; Caco-2 Cells; Carcinoma, Hepatocellular; C | 2005 |
Differential UGT1A1 induction by chrysin in primary human hepatocytes and HepG2 Cells.
Topics: Adolescent; Adult; Aged; Black People; Carcinogens; Carcinoma, Hepatocellular; Cell Line, Tumor; Cel | 2005 |
Cytochrome P450 2C11 5'-flanking region and promoter: regulation by aromatic hydrocarbons in vitro.
Topics: 5' Flanking Region; Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Carcinoma, Hepatocellular | 2008 |
Glucocorticoid enhancement of aflatoxin B1 cytotoxicity in differentiated rat hepatoma cultures.
Topics: Aflatoxin B1; Aflatoxins; Animals; Biotransformation; Carcinoma, Hepatocellular; Cell Differentiatio | 1980 |
The human CYP1A2 gene and induction by 3-methylcholanthrene. A region of DNA that supports AH-receptor binding and promoter-specific induction.
Topics: Animals; Base Sequence; Binding Sites; Carcinoma, Hepatocellular; Cell Line; Cell Nucleus; Cytochrom | 1994 |
Regulation of cytochrome P450 in cultured human colonic cells.
Topics: Adenocarcinoma; Animals; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; beta-Naphthoflavone; Carcinoma | 1993 |
Induction of cytochrome P450IA1 and its recombinant construct in H4IIE rat hepatoma cells.
Topics: Animals; Benzo(a)pyrene; Benzofurans; Blotting, Western; Carcinoma, Hepatocellular; Chloramphenicol | 1993 |
Rifampicin and isoniazid increase acetaminophen and isoniazid cytotoxicity in human HepG2 hepatoma cells.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Antitubercular Agents; Carcinoma, Hepatocellular; Cell Surv | 1997 |
Signaling pathways in the induction of c-fos and c-jun proto-oncogenes by 3-methylcholanthrene.
Topics: Calcium-Calmodulin-Dependent Protein Kinases; Carcinoma, Hepatocellular; Chloramphenicol O-Acetyltra | 1997 |
Extensive metabolism of the flavonoid chrysin by human Caco-2 and Hep G2 cells.
Topics: Animals; Apigenin; Arylsulfotransferase; Caco-2 Cells; Carcinoma, Hepatocellular; Cell Line; Chromat | 1999 |
Diflubenzuron, a benzoyl-urea insecticide, is a potent inhibitor of TCDD-induced CYP1A1 expression in HepG2 cells.
Topics: Carcinoma, Hepatocellular; Cytochrome P-450 CYP1A1; Diflubenzuron; Environmental Pollutants; Enzyme | 2000 |
Induction of cytochrome P450 1A1 in human hepatoma HepG2 cells by 6-nitrochrysene.
Topics: Benzopyrene Hydroxylase; Carcinoma, Hepatocellular; Chrysenes; Cytochrome P-450 CYP1A1; Dose-Respons | 2000 |
Aromatic hydrocarbon receptor (AhR).AhR nuclear translocator- and p53-mediated induction of the murine multidrug resistance mdr1 gene by 3-methylcholanthrene and benzo(a)pyrene in hepatoma cells.
Topics: Animals; Aryl Hydrocarbon Receptor Nuclear Translocator; ATP Binding Cassette Transporter, Subfamily | 2001 |
Effects of 3-methylcholanthrene and aspirin co-administration on ALDH3A1 in HepG2 cells.
Topics: Aldehyde Dehydrogenase; Aspirin; Carcinoma, Hepatocellular; Cell Survival; Drug Interactions; Glutat | 2001 |
Serum induces a transcriptional activation of CYP1A1 gene in HepG2 independently of the AhR pathway.
Topics: Adenocarcinoma; Animals; Blood; Carcinoma, Hepatocellular; Cattle; Chloramphenicol O-Acetyltransfera | 2001 |
Induction of UDP-glucuronosyltransferase 1A8 mRNA by 3-methylcholanthene in rat hepatoma cells.
Topics: Amino Acid Sequence; Animals; Base Sequence; Carcinoma, Hepatocellular; Dactinomycin; Glucuronosyltr | 2002 |
Quantitative assessment of mutagenic potential of water via EROD-microbioassessment.
Topics: Animals; Benzo(a)pyrene; Carcinoma, Hepatocellular; Cytochrome P-450 CYP1A1; Dose-Response Relations | 2002 |
Properties of aryl hydrocarbon hydroxylase in microsomes of Morris hepatoma 5123D and the host liver.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Carcinoma, Hepatocellular; Epoxide Hydrolases; Flavonoids; H | 1975 |
Glutathione and gamma glutamyl transpeptidase in rat liver during chemical carcinogenesis.
Topics: 2-Acetylaminofluorene; Animals; Carcinoma, Hepatocellular; Chloramphenicol; gamma-Glutamyltransferas | 1976 |
BCG therapy of pleural and peritoneal growth of transplanted rat tumours.
Topics: Animals; Azo Compounds; BCG Vaccine; Benzene; Breast Neoplasms; Carcinoma, Hepatocellular; Female; F | 1975 |
[The tumor-tetanus assay--experimental studies on the biological differentiation between carcinogenesis and organ regeneration of the rat (author's transl)].
Topics: Agglutination Tests; Animals; Antibodies, Neoplasm; Antibody Formation; Carcinoma 256, Walker; Carci | 1975 |
Tumor induction by carcinogenic agents in aquarium fish.
Topics: 2-Acetylaminofluorene; 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenoma; Adenoma, Bile Duct | 1975 |
Zinc intake, neoplastic DNA synthesis, and chemical carcinogenesis in rats and mice.
Topics: Animals; Carcinoma, Hepatocellular; Depression, Chemical; DNA, Neoplasm; Dose-Response Relationship, | 1975 |
Studies on rat complement. II. Complement level in experimental tumor in rats.
Topics: Animals; Carcinoma, Hepatocellular; Complement C3; Complement C4; Complement System Proteins; Coryne | 1975 |
Inhibition of cell-mediated cytotoxicity to chemically induced rat tumours by soluble tumour and embryo cell extracts.
Topics: Animals; Antigens, Neoplasm; Azo Compounds; Carcinoembryonic Antigen; Carcinoma, Hepatocellular; Cel | 1976 |
Axyl hydrocarbon hydroxylase in Morris hepatoma 5123D.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Carcinoma, Hepatocellular; Cell Nucleus; Female; Flavonoids; | 1975 |
Characterization of microsomal methyl sterol demethylase in two Morris hepatomas.
Topics: Animals; Buffers; Carcinoma, Hepatocellular; Cholesterol; Cholestyramine Resin; Cyanides; Cytochrome | 1976 |
Biochemistry and enzyme induction in MC-29 virus-induced transplantable avian hepatoma.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Carcinoma, Hepatocellular; Cell Nucleus; Chickens; Cytoplasm | 1976 |
Macrophage migration inhibition-activity after implantation of methylcholanthrene-induced sarcoma, Ehrlich ascites cancer or mouse ascites hepatoma-134 cancer cells in mice.
Topics: Animals; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Cell Migration Inhibition; Immunity, C | 1976 |
Studies on the microcytotoxicity test. I. Evidence that the effects of normal lymphoid cells on tumour cell growth in microtest plates may be caused by non-immunological modifications of the culture medium.
Topics: Animals; Carcinoma, Hepatocellular; Cell Fractionation; Cell Transformation, Neoplastic; Culture Med | 1976 |
A comparison of steroid glucuronlytransferases of rat liver and hepatoma, and effects of phenobarbitone and 3-methylcholanthrene induction.
Topics: Animals; Carcinoma, Hepatocellular; Enzyme Induction; Estradiol; Estrone; Glucuronosyltransferase; K | 1976 |
Tumour circulation. An experimental study in the rat with a comparison of different methods for estimation of tumour blood flow.
Topics: Angiography; Animals; Antipyrine; Carcinoma, Hepatocellular; Iodine Radioisotopes; Liver Neoplasms; | 1976 |
Guinea pig cell-mediated tumor immunity: the chromium release assay detects both cytolysis and serum blocking for syngeneic chemically-induced tumors.
Topics: Animals; Binding, Competitive; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Chromium | 1979 |
Effect of heat and glutaraldehyde upon the immunogenicity of Meth A sarcoma cells.
Topics: Aldehydes; Animals; Antigens, Neoplasm; Carcinoma, Hepatocellular; Glutaral; Hot Temperature; Immuni | 1979 |
Effect of enzyme inducers on metabolism of 1-nitropyrene in human hepatoma cell line HepG2.
Topics: Carcinoma, Hepatocellular; Enzyme Induction; Humans; Liver Neoplasms; Methylcholanthrene; Mutagens; | 1991 |
Porphyrin synthesis by human hepatocytes and HepG2 cells--effects of enzyme inducers and delta-aminolevulinic acid.
Topics: Aminolevulinic Acid; Carcinoma, Hepatocellular; Cells, Cultured; Cytochrome P-450 Enzyme System; Dim | 1991 |
Role of cytochrome P450 in the control of the production of erythropoietin.
Topics: Carcinoma, Hepatocellular; Cobalt; Cysteamine; Cytochrome P-450 Enzyme System; Ditiocarb; Erythropoi | 1990 |
Dexamethasone-mediated potentiation of P450IA1 induction in H4IIEC3/T hepatoma cells is dependent on a time-consuming process and associated with induction of the Ah receptor.
Topics: Animals; Benzo(a)pyrene; Carcinoma, Hepatocellular; Cytochrome P-450 Enzyme System; Cytosol; Dexamet | 1990 |
delta-Aminolaevulinate synthase in human HepG2 hepatoma cells. Repression by haemin and induction by chemicals.
Topics: 5-Aminolevulinate Synthetase; Carcinoma, Hepatocellular; Dimethyl Sulfoxide; Dose-Response Relations | 1989 |
Differential induction of human liver UDP-glucuronosyltransferase activities by phenobarbital-type inducers.
Topics: Acetaminophen; Adolescent; Adult; Benzopyrenes; Bilirubin; Carcinoma, Hepatocellular; Enzyme Inducti | 1987 |
Effect of phenobarbital and 3-methylcholanthrene on aldehyde dehydrogenase activity in cultures of HepG2 cells and normal human hepatocytes.
Topics: Aldehyde Dehydrogenase; Aldehydes; Benzaldehydes; Carcinoma, Hepatocellular; Cells, Cultured; Liver; | 1987 |
Biological tests of carcinogenic activity.
Topics: Animals; Azo Compounds; Biological Assay; Carcinogens; Carcinoma, Hepatocellular; Carcinoma, Papilla | 1968 |
Hemoproteins in microsomes in liver of tumor-bearing rats.
Topics: Animals; Carcinogens; Carcinoma, Hepatocellular; Catalase; Coloring Agents; Cytochromes; Fibrosarcom | 1965 |
Studies on leukemia in mice associated with a transplantable methylcholanthrene-induced hepatoma.
Topics: Animals; Carcinoma, Hepatocellular; Leukemia, Experimental; Leukemia, Myeloid; Liver Neoplasms; Meth | 1966 |
Induced hyperlipemia and the dissemination of tumor cells.
Topics: Animals; Carcinoma, Hepatocellular; Emulsions; Hyperlipidemias; Injections, Intravenous; Liver Neopl | 1967 |
[The cancer problem in fundamental research].
Topics: Animals; Antigens; Antineoplastic Agents; Carcinoma, Hepatocellular; Culture Techniques; Cyclophosph | 1966 |
Pressure effects on survival of mice with transplantable leukaemia.
Topics: Animals; Atmospheric Pressure; Body Weight; Carcinoma, Hepatocellular; Leukemia; Liver Neoplasms; Me | 1968 |
[Delayed type hypersensitivity in tumor-bearing rats].
Topics: Animals; Antigens; Carcinoma, Hepatocellular; Freund's Adjuvant; Hypersensitivity, Delayed; Immuniza | 1967 |
Effect of some mutagenic virogens and carcinogens on deoxyribonucleic acid.
Topics: Animals; Ascitic Fluid; Benzopyrenes; Bombyx; Carcinogens; Carcinoma, Hepatocellular; Cattle; Centri | 1968 |
Sensitivity of newborn mice to carcinogenic agents.
Topics: Adenocarcinoma; Adenoma; Animals; Animals, Newborn; Benz(a)Anthracenes; Carcinogens; Carcinoma, Hepa | 1968 |
[Experimental hematogenous metastasis of a fibrosarcoma in animals with and without spleen].
Topics: Animals; Antibody Formation; Carcinoma, Hepatocellular; Fibrosarcoma; Liver Neoplasms; Lung Neoplasm | 1969 |
Benzpyrene hydroxylase activity and its induction by methylcholanthrene in Morris hepatomas, in host livers, in adult livers, and in rat liver during development.
Topics: Animals; Benzopyrenes; Carcinoma, Hepatocellular; Cycloheximide; Dactinomycin; Enzyme Induction; Fem | 1970 |
[A new animal for experimental oncologic research--the Dzhungarian hamster].
Topics: Animals; Animals, Laboratory; Benz(a)Anthracenes; Carcinoma, Hepatocellular; Carcinoma, Squamous Cel | 1970 |
Effects of 3-methylcholanthrene pretreatment on microsomal hydroxylation of 2-acetamidofluorene by various rat hepatomas.
Topics: Animals; Carcinogens; Carcinoma, Hepatocellular; Female; Fluorenes; Kidney; Liver; Liver Neoplasms; | 1970 |
Effect of 3-methylcholanthrene on hyperplastic and early neoplastic hepatic lesions induced in rats by carbon tetrachloride.
Topics: Age Factors; Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Carcinogens; Carcinoma, | 1970 |
Experimental studies on trauma and metastasis formation.
Topics: Animals; Blood Coagulation; Carcinoma, Hepatocellular; Dextrans; Female; Fibrinolysis; Heparin; Inje | 1968 |
Enzyme patterns in a group of transplantable mouse hepatomas of different growth rates.
Topics: Animals; Carboxy-Lyases; Carcinoma, Hepatocellular; Growth; Humans; Inbreeding; Liver; Liver Neoplas | 1971 |
Demonstration of cell-surface antigens on chemically induced tumors.
Topics: Animals; Antibody Specificity; Antigens; Antigens, Neoplasm; Carcinogens; Carcinoma; Carcinoma, Hepa | 1971 |
Tumour specific and embryonic antigen expression of chemically induced rat tumours.
Topics: Animals; Antigens; Antigens, Neoplasm; Carcinoma, Hepatocellular; Cell Membrane; Cytotoxicity Tests, | 1972 |
Intracisternal A-type and C-type particles observed in pulmonary tumors in mice.
Topics: Adenocarcinoma; Animals; Antigens, Viral; Ascites; Carcinoma, Hepatocellular; Culture Techniques; Fl | 1972 |
Embryonic antigen expression in chemically induced rat hepatomas and sarcomas.
Topics: Animals; Antigen-Antibody Reactions; Antigens, Neoplasm; Carcinoembryonic Antigen; Carcinoma, Hepato | 1972 |
Effect of 1-naphthyl isothiocyanate and 3-methylcholanthrene on hepatocarcinogenesis in rats treated with diethylnitrosoamine.
Topics: Animals; Bile Ducts, Intrahepatic; Body Weight; Carcinoma, Hepatocellular; Fibrosarcoma; Hemangioend | 1973 |
The induction of tumours in the guinea-pig with methylcholanthrene and diethylnitrosamine and their propagation in vivo and in vitro.
Topics: Animals; Carcinoma, Hepatocellular; Fibrosarcoma; Guinea Pigs; Liposarcoma; Liver Neoplasms; Methylc | 1973 |
Aryl hydrocarbon hydroxylase induction in mammalian liver cell culture. IV. Stimulation of the enzyme activity in established cell lines derived from rat or mouse hepatoma and from normal rat liver.
Topics: Animals; Benz(a)Anthracenes; Benzopyrenes; Carcinoma, Hepatocellular; Cell Line; Cricetinae; Culture | 1973 |
Isolation and chemical characterization of mucopolysaccharides from rat tumors.
Topics: Animals; Carcinoma, Hepatocellular; Chondroitin; Chromatography, Ion Exchange; Electrophoresis; Gluc | 1974 |
Neoplasms and amyloidosis in strains of mice treated with 3-methylcholanthrene.
Topics: Adenoma; Amyloidosis; Animals; Carcinoma, Hepatocellular; Carcinoma, Squamous Cell; Female; Liver Ne | 1974 |
Influence of age and 3-methylcholanthrene on azo-dye carcinogenesis and metabolism of p-dimethylaminoazobenzene in rat liver.
Topics: Age Factors; Animals; Azo Compounds; Carcinoma, Hepatocellular; DNA; Liver; Liver Neoplasms; Male; M | 1973 |
Radiation-killed BCG in the treatment of transplanted rat tumours.
Topics: Animals; Azo Compounds; BCG Vaccine; Benzene Derivatives; Carcinoma, Hepatocellular; Cell Survival; | 1974 |
A preliminary investigation into the role of immunity in modifying the blood- borne spread of chemically induced rat sarcomas.
Topics: Animals; Benzopyrenes; Carcinogens; Carcinoma, Hepatocellular; Ethionine; Graft Rejection; Immunizat | 1974 |