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3-methylcholanthrene and Genome Instability

3-methylcholanthrene has been researched along with Genome Instability in 1 studies

Methylcholanthrene: A carcinogen that is often used in experimental cancer studies.
3-methylcholanthrene : A pentacyclic ortho- and peri-fused polycyclic arene consisting of a dihydrocyclopenta[ij]tetraphene ring system with a methyl substituent at the 3-position.

Research Excerpts

ExcerptRelevanceReference
" We investigated murine soft tissue sarcomas generated by oncogenic alterations (KrasG12D activation and p53 deletion), carcinogens (3-methylcholanthrene [MCA] or ionizing radiation), and in a novel model combining both factors (MCA plus p53 deletion)."3.91Mutational landscape in genetically engineered, carcinogen-induced, and radiation-induced mouse sarcoma. ( Caraballo, I; Daniel, AR; Delaney, JR; Gresham, J; Kirsch, DG; Lee, CL; Luo, L; Mowery, YM; Owzar, K; Qin, X; Sibley, AB; Van Mater, D; Wang, X; Wisdom, AJ; Zhang, D, 2019)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lee, CL1
Mowery, YM1
Daniel, AR1
Zhang, D1
Sibley, AB1
Delaney, JR1
Wisdom, AJ1
Qin, X1
Wang, X1
Caraballo, I1
Gresham, J1
Luo, L1
Van Mater, D1
Owzar, K1
Kirsch, DG1

Other Studies

1 other study available for 3-methylcholanthrene and Genome Instability

ArticleYear
Mutational landscape in genetically engineered, carcinogen-induced, and radiation-induced mouse sarcoma.
    JCI insight, 2019, 07-11, Volume: 4, Issue:13

    Topics: Animals; Carcinogenesis; Carcinogens; DNA Mutational Analysis; Exome Sequencing; Genomic Instability

2019