3-methylcholanthrene has been researched along with Genetic Predisposition in 8 studies
Methylcholanthrene: A carcinogen that is often used in experimental cancer studies.
3-methylcholanthrene : A pentacyclic ortho- and peri-fused polycyclic arene consisting of a dihydrocyclopenta[ij]tetraphene ring system with a methyl substituent at the 3-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| " These mice developed fibrosarcomas after the subcutaneous injection of 3-methylcholanthrene with an incidence 1." | 3.76 | Mutant mouse p53 transgene elevates the chemical induction of tumors that respond to gene silencing with siRNA. ( Ishii, H; Katsube, T; Noda, Y; Ochiya, T; Ootsuyama, A; Takeshita, F; Tanooka, H; Tatsumi, K; Tsuji, H, 2010) |
| "Vanadium pentoxide (V2O5) is a component of PM derived from fuel combustion as well as a source of occupational exposure in humans." | 1.36 | Vanadium pentoxide induces pulmonary inflammation and tumor promotion in a strain-dependent manner. ( Bauer, AK; Rondini, EA; Walters, DM, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 5 (62.50) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tanooka, H | 1 |
| Tatsumi, K | 1 |
| Tsuji, H | 1 |
| Noda, Y | 1 |
| Katsube, T | 1 |
| Ishii, H | 1 |
| Ootsuyama, A | 1 |
| Takeshita, F | 1 |
| Ochiya, T | 1 |
| Rondini, EA | 1 |
| Walters, DM | 1 |
| Bauer, AK | 1 |
| Nishikawa, H | 1 |
| Kato, T | 1 |
| Tawara, I | 1 |
| Takemitsu, T | 1 |
| Saito, K | 1 |
| Wang, L | 1 |
| Ikarashi, Y | 1 |
| Wakasugi, H | 1 |
| Nakayama, T | 1 |
| Taniguchi, M | 1 |
| Kuribayashi, K | 1 |
| Old, LJ | 1 |
| Shiku, H | 1 |
| Wang, IC | 1 |
| Meliton, L | 1 |
| Tretiakova, M | 1 |
| Costa, RH | 1 |
| Kalinichenko, VV | 1 |
| Kalin, TV | 1 |
| Sadi, AM | 1 |
| Toda, T | 1 |
| Kiyuna, M | 1 |
| Tamamoto, T | 1 |
| Oku, H | 1 |
| Miller, MS | 1 |
| Gressani, KM | 1 |
| Leone-Kabler, S | 1 |
| Townsend, AJ | 1 |
| Malkinson, AM | 1 |
| O'Sullivan, MG | 1 |
| Cretney, E | 1 |
| Takeda, K | 1 |
| Yagita, H | 1 |
| Glaccum, M | 1 |
| Peschon, JJ | 1 |
| Smyth, MJ | 1 |
| Malkinson, A | 1 |
| Radcliffe, R | 1 |
| Bauer, A | 1 |
| Dwyer-Nield, L | 1 |
| Kleeberger, S | 1 |
1 review available for 3-methylcholanthrene and Genetic Predisposition
| Article | Year |
|---|---|
Differential sensitivity to lung tumorigenesis following transplacental exposure of mice to polycyclic hydrocarbons, heterocyclic amines, and lung tumor promoters.
Topics: Adenocarcinoma; Adenoma; Animals; Aryl Hydrocarbon Hydroxylases; Butylated Hydroxytoluene; Carcinoge | 2000 |
7 other studies available for 3-methylcholanthrene and Genetic Predisposition
| Article | Year |
|---|---|
Mutant mouse p53 transgene elevates the chemical induction of tumors that respond to gene silencing with siRNA.
Topics: Animals; Apoptosis; Blotting, Western; Female; Fibrosarcoma; Gene Silencing; Genes, p53; Genetic Pre | 2010 |
Vanadium pentoxide induces pulmonary inflammation and tumor promotion in a strain-dependent manner.
Topics: Air Pollutants; Animals; Carcinogens; Chemokines; Disease Models, Animal; Genetic Predisposition to | 2010 |
Accelerated chemically induced tumor development mediated by CD4+CD25+ regulatory T cells in wild-type hosts.
Topics: Animals; Antigens, CD1; Antigens, CD1d; Carcinogens; CD4 Antigens; CD4-Positive T-Lymphocytes; Cell | 2005 |
Transgenic expression of the forkhead box M1 transcription factor induces formation of lung tumors.
Topics: Adenoma; Animals; Butylated Hydroxytoluene; Cyclooxygenase 2; DNA Replication; Forkhead Box Protein | 2008 |
Effect of 20-methylcholanthrene on the development of atherosclerosis in LAP quails.
Topics: Animals; Aorta; Arteriosclerosis; Brachiocephalic Trunk; Cholesterol, Dietary; Clone Cells; Coturnix | 1994 |
Increased susceptibility to tumor initiation and metastasis in TNF-related apoptosis-inducing ligand-deficient mice.
Topics: Adenocarcinoma; Animals; Apoptosis Regulatory Proteins; Cell Division; Cell Transformation, Neoplast | 2002 |
Quantitative trait loci that regulate susceptibility to both butylated hydroxytoluene-induced pulmonary inflammation and lung tumor promotion in CXB recombinant inbred mice.
Topics: Animals; Butylated Hydroxytoluene; Carcinogens; Chromosome Mapping; Genetic Predisposition to Diseas | 2002 |