3-methylcholanthrene has been researched along with Endometrial Neoplasms in 3 studies
Methylcholanthrene: A carcinogen that is often used in experimental cancer studies.
3-methylcholanthrene : A pentacyclic ortho- and peri-fused polycyclic arene consisting of a dihydrocyclopenta[ij]tetraphene ring system with a methyl substituent at the 3-position.
Endometrial Neoplasms: Tumors or cancer of ENDOMETRIUM, the mucous lining of the UTERUS. These neoplasms can be benign or malignant. Their classification and grading are based on the various cell types and the percent of undifferentiated cells.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Dose-response studies revealed that the concentration of 3MC required to half-maximally activate transcription (EC(50)) was >100-fold higher for an ER reporter (27-57 muM) than for an AhR reporter (86-250 nM) in both MCF-7 cells and in human endometrial cancer Ishikawa cells." | 1.33 | Aryl hydrocarbon receptor-independent activation of estrogen receptor-dependent transcription by 3-methylcholanthrene. ( Shipley, JM; Waxman, DJ, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Qu, XL | 1 |
| Wang, SY | 1 |
| Jia, YJ | 1 |
| Guan, Y | 1 |
| TAKI, I | 1 |
| IIJIMA, H | 1 |
| Shipley, JM | 1 |
| Waxman, DJ | 1 |
3 other studies available for 3-methylcholanthrene and Endometrial Neoplasms
| Article | Year |
|---|---|
Aryl hydrocarbon receptor exogenous ligand 3-methylchoranthrene inhibited endometrial cancer cells proliferation.
Topics: Antineoplastic Agents; Basic Helix-Loop-Helix Transcription Factors; Cell Line, Tumor; Cell Movement | 2014 |
A NEW METHOD OF PRODUCING ENDOMETRIAL CANCER IN MICE.
Topics: Adenocarcinoma; Animals; Carcinoma, Squamous Cell; Endometrial Neoplasms; Endometrium; Female; Human | 1963 |
Aryl hydrocarbon receptor-independent activation of estrogen receptor-dependent transcription by 3-methylcholanthrene.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Dose-Response Relationship, Drug; Endometrial Neoplasms | 2006 |