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3-methylcholanthrene and Delayed Hypersensitivity

3-methylcholanthrene has been researched along with Delayed Hypersensitivity in 39 studies

Methylcholanthrene: A carcinogen that is often used in experimental cancer studies.
3-methylcholanthrene : A pentacyclic ortho- and peri-fused polycyclic arene consisting of a dihydrocyclopenta[ij]tetraphene ring system with a methyl substituent at the 3-position.

Research Excerpts

ExcerptRelevanceReference
"The relationship between tumor resistance and the antitumor delayed hypersensitivity reaction (TDHR) after resection of the tumor was studied by using the syngeneic 3-methylcholanthrene-induced murine tumor, MCA-DDD."7.66Antitumor immunity after surgical removal of 3-methylcholanthrene-induced murine tumors: correlation between resistance and delayed hypersensitivity reaction. ( Abe, S; Mizuno, D; Yamazaki, M, 1978)
"The relationship between tumor resistance and the antitumor delayed hypersensitivity reaction (TDHR) after resection of the tumor was studied by using the syngeneic 3-methylcholanthrene-induced murine tumor, MCA-DDD."3.66Antitumor immunity after surgical removal of 3-methylcholanthrene-induced murine tumors: correlation between resistance and delayed hypersensitivity reaction. ( Abe, S; Mizuno, D; Yamazaki, M, 1978)
"Whether the common human cancers possess tumour-specific antigens which produce an immune response in the host still remains the crucial question in tumour immunology."2.36Where is the immunology in cancer? ( Bray, AE, 1978)
"The growth of Meth A (MA) tumors was suppressed in tumor-antigen-specific manner in BALB/c mice immunized with mitomycin C-treated MA (MMC-MA) cells in saline or in Freund's complete adjuvant (FCA)."1.27Differing contribution of various effector cells in the elimination of syngeneic or allogeneic cells. ( Himeno, K; Matsumoto, T; Miake, S; Mitani, M; Mori, K; Nomoto, K, 1986)
"Seven transplantable lines of squamous cell carcinoma of the skin initiated in BALB/c mice by skin painting with methycholanthrene were systematically tested for cross-reactivity of their tumor rejection antigens in a 7 X 7 matrix."1.26Common tumor rejection antigens in methylcholanthrene-induced squamous cell carcinomas of mice detected by tumor protection and a radioisotopic footpad assay. ( Boone, CW; Economou, GC; Takelchi, N, 1977)

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-199036 (92.31)18.7374
1990's3 (7.69)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zákány, J1
Jánossy, T1
Németh, P1
Chihara, G1
Fachet, J1
Petri, G1
Kearney, R2
Harrop, P1
Jessup, JM1
Kahan, BD1
LeGrue, SJ1
Rutzky, L1
Pellis, NR1
Perry, LL1
Dorf, ME1
Bach, BA1
Benacerraf, B1
Greene, MI1
Frank, DM2
Yamashita, TS1
Blumer, JL2
Hamuro, J1
Takatsuki, F1
Suga, T1
Kikuchi, T1
Suzuki, M1
Economou, GC1
Takelchi, N1
Boone, CW1
Abe, S1
Yamazaki, M1
Mizuno, D1
Yamada, Y1
Mizushima, Y1
Hosokawa, M1
Kobayashi, H1
Yamawaki, M1
Azuma, I1
Saiki, I1
Uemiya, M1
Aoki, O1
Ennyu, K1
Yamamura, Y1
Nelson, DS2
Nelson, M1
Hopper, KE2
Blanden, RV1
Gardner, ID1
Bray, AE1
Tamura, S1
Kojima, A1
Egashira, Y1
Yamada, H1
Scott, MT1
Warner, SL1
Bussiere, JL1
Mather, GG1
Exon, JH1
Nagae, H1
Mitani, M2
Mori, K2
Himeno, K2
Nomoto, K2
Kadhim, SA1
Rees, RC1
Barrington-Leigh, J1
Matsumoto, T1
Miake, S1
Edelman, AS1
Xue, B1
Sanchez, P1
Thorbecke, GJ1
McLaughlin, AP1
Gittes, RF1
Sobbe, A1
Haferkamp, O1
Wells, JH1
Cain, WA1
Wells, RS1
Bozalis, JR1
Cohen, AM1
Holmes, EC1
Reisfeld, RA1
Morton, DL1
Chung, EB1
Zbar, B1
Rapp, HJ1
Brannen, GE1
Adams, JS1
Santos, GW1
Silverman, DA1
Rose, NR1
Dale, MM1
Hedges, JR1
Grant, JP1
Ladisch, S1
Wells, SA1
Pomeranz, JR1
Halliday, WJ2
Bloom, BR1
Bennett, B1
Oettgen, HF2
McLean, EP2
Old, LJ2
Milas, L1
Dekaris, D1
Horvat, M1
Carswell, EA1
Webb, M1

Reviews

1 review available for 3-methylcholanthrene and Delayed Hypersensitivity

ArticleYear
Where is the immunology in cancer?
    The Australian and New Zealand journal of surgery, 1978, Volume: 48, Issue:1

    Topics: Animals; Antibodies, Neoplasm; Humans; Hypersensitivity, Delayed; Immunity, Cellular; Methylcholanth

1978

Other Studies

38 other studies available for 3-methylcholanthrene and Delayed Hypersensitivity

ArticleYear
Mechanism of the A/Ph.MC.S1 tumor graft rejection in syngeneic mice.
    Gan, 1983, Volume: 74, Issue:5

    Topics: Animals; Female; Fibrosarcoma; Graft Rejection; Hypersensitivity, Delayed; Macrophage Migration-Inhi

1983
Modulation of anti-tumour immunity induced by syngeneic mitomycin C-treated murine tumour cells.
    International journal of cancer, 1984, Aug-15, Volume: 34, Issue:2

    Topics: Animals; Antigens, Neoplasm; Cross Reactions; Female; Graft Rejection; Hypersensitivity, Delayed; Im

1984
Soluble factors from murine and human tumors induce suppressor cells.
    The Journal of surgical research, 1984, Volume: 36, Issue:6

    Topics: Adenocarcinoma; Animals; Cell Line; Colonic Neoplasms; Dinitrochlorobenzene; Female; Fibrosarcoma; H

1984
Mechanisms of regulation of cell-mediated immunity: anti-I-A alloantisera interfere with induction and expression of T-cell-mediated immunity to cell-bound antigen in vivo.
    Clinical immunology and immunopathology, 1980, Volume: 15, Issue:3

    Topics: Animals; Antigens, Surface; Female; Fibrosarcoma; H-2 Antigens; Hypersensitivity, Delayed; Immunity,

1980
Genetic differences in methylcholanthrene-mediated suppression of cutaneous delayed hypersensitivity in mice.
    Toxicology and applied pharmacology, 1982, Jun-15, Volume: 64, Issue:1

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Blood Cell Count; Female; Hypersensitivity, Delayed; Liver;

1982
Synergistic antimetastatic effects of lentinan and interleukin 2 with pre- and post-operative treatments.
    Japanese journal of cancer research : Gann, 1994, Volume: 85, Issue:12

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; CD4-Positive T-Lymphocytes; CD8-Positive T-

1994
Common tumor rejection antigens in methylcholanthrene-induced squamous cell carcinomas of mice detected by tumor protection and a radioisotopic footpad assay.
    Cancer research, 1977, Volume: 37, Issue:1

    Topics: Animals; Antigens, Neoplasm; Antigens, Viral; Carcinoma, Squamous Cell; Cross Reactions; Epitopes; G

1977
Antitumor immunity after surgical removal of 3-methylcholanthrene-induced murine tumors: correlation between resistance and delayed hypersensitivity reaction.
    Gan, 1978, Volume: 69, Issue:3

    Topics: Animals; Antigens, Neoplasm; Cell Survival; Epitopes; Hypersensitivity, Delayed; Immunity, Cellular;

1978
Detection of delayed hypersensitivity reaction in rats by radioisotopic footpad assay with sodium deoxycholate extract and mitomycin-C-treated tumor cells.
    Gan, 1978, Volume: 69, Issue:4

    Topics: Animals; Antigens, Neoplasm; Deoxycholic Acid; Epitopes; Fibrosarcoma; Hypersensitivity, Delayed; Io

1978
Antitumor activity of squalene-treated cell-wall skeleton of Nocardia rubra in mice.
    Gan, 1978, Volume: 69, Issue:5

    Topics: Animals; Cell Wall; Guinea Pigs; Hypersensitivity, Delayed; Leukemia, Experimental; Mast-Cell Sarcom

1978
Mechanism of resistance of mice to syngeneic methylcholanthrene induced fibrosarcomas.
    Advances in experimental medicine and biology, 1979, Volume: 121B

    Topics: Animals; Carrageenan; Cell Count; Cell Movement; Cell Transformation, Neoplastic; Fibrosarcoma; Huma

1979
Failure of immunogenic tumors to elicit cytolytic T cells in syngeneic hosts.
    Cancer letters, 1978, Volume: 5, Issue:2

    Topics: Animals; Antigens, Neoplasm; Cytotoxicity, Immunologic; Fibrosarcoma; H-2 Antigens; Hypersensitivity

1978
Augmentation of delayed-type hypersensitivity and resistance against allogeneic or syngeneic methylcholanthrene-induced tumors in mice preimmunized with the tumor extracts.
    Japanese journal of medical science & biology, 1979, Volume: 32, Issue:6

    Topics: Animals; Antigens, Neoplasm; Female; Hypersensitivity, Delayed; Immunization; Methylcholanthrene; Mi

1979
[The immunopotentiating action of BCG and its various effects on tumors (author's transl)].
    Kekkaku : [Tuberculosis], 1978, Volume: 53, Issue:1

    Topics: Animals; BCG Vaccine; Female; Fibrosarcoma; Hypersensitivity, Delayed; Male; Methylcholanthrene; Mic

1978
The accumulated effects of repeated systemic or local injections of low doses of Corynebacterium parvum in mice.
    Cancer research, 1976, Volume: 36, Issue:4

    Topics: Adjuvants, Immunologic; Animals; Antibodies, Bacterial; Benzopyrenes; Female; Hypersensitivity, Dela

1976
Effect of cyclosporine on 3-methylcholanthrene-induced carcinogenesis and immune responses in the rat.
    Immunobiology, 1991, Volume: 182, Issue:3-4

    Topics: Animals; Antibody Formation; Cyclosporins; Cytotoxicity, Immunologic; Dinoprostone; Fibrosarcoma; Hy

1991
[Effects of SSM, an extract from human type tubercle bacilli, on syngenic guinea pig tumors].
    Nihon Ika Daigaku zasshi, 1990, Volume: 57, Issue:3

    Topics: Animals; Antineoplastic Agents; Guinea Pigs; Hypersensitivity, Delayed; Lipids; Mannans; Methylchola

1990
Anti-tumor cytostatic mechanism and delayed-type hypersensitivity against a syngeneic murine tumor. Comparison between neonatally thymectomized mice and congenitally athymic nude mice.
    Journal of immunology (Baltimore, Md. : 1950), 1989, Mar-15, Volume: 142, Issue:6

    Topics: Animals; Animals, Newborn; Cell Division; Cytotoxicity Tests, Immunologic; Cytotoxicity, Immunologic

1989
The roles of two peritoneal T-lymphocyte populations in the in vivo rejection of methylcolanthrene-induced sarcoma.
    Cellular immunology, 1985, Volume: 90, Issue:1

    Topics: Animals; Antigens, Neoplasm; Cross Reactions; Epitopes; Female; Graft Rejection; Humans; Hypersensit

1985
Alteration of methylcholanthrene-mediated suppression of cutaneous delayed hypersensitivity by benzoflavone treatment of C57BL/6J mice.
    Toxicology and applied pharmacology, 1988, Volume: 95, Issue:1

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme

1988
Differing contribution of various effector cells in the elimination of syngeneic or allogeneic cells.
    Journal of clinical & laboratory immunology, 1986, Volume: 19, Issue:2

    Topics: Animals; Antibodies, Neoplasm; Antibody Specificity; Cells, Cultured; Cytotoxicity, Immunologic; Fib

1986
Cross-reactive cellular and humoral immunity to carcinogen-induced chicken fibrosarcomas. I. Protective cross-immunity between transplantable tumor lines.
    Journal of immunology (Baltimore, Md. : 1950), 1985, Volume: 135, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antibodies, Neoplasm; Antibody Formation; Antigens, Neopl

1985
Spontaneous tumor regression. Experimental aspects.
    Urology, 1974, Volume: 3, Issue:5

    Topics: Animals; Antibodies; Antibody Formation; Antigens, Neoplasm; B-Lymphocytes; Bone Neoplasms; Epitopes

1974
[Delayed type hypersensitivity in tumor-bearing rats].
    Zeitschrift fur Krebsforschung, 1967, Volume: 70, Issue:2

    Topics: Animals; Antigens; Carcinoma, Hepatocellular; Freund's Adjuvant; Hypersensitivity, Delayed; Immuniza

1967
Suppression of tuberculin and phytohemagglutinin skin tests by large tumors in inbred mice.
    International archives of allergy and applied immunology, 1974, Volume: 47, Issue:3

    Topics: Animals; Female; Fibrosarcoma; Freund's Adjuvant; Hypersensitivity, Delayed; Immune Tolerance; Lecti

1974
Host immunity to growing sarcomas: tumor-specific serum inhibition of tumor-specific cellular immunity.
    Cancer, 1973, Volume: 31, Issue:1

    Topics: Animals; Antibody Specificity; Antigens, Neoplasm; Carcinoma; Cell Line; Female; Fibroblasts; Guinea

1973
Delayed cutaneous hypersensitivity to cell-free tumor antigens.
    Cancer research, 1973, Volume: 33, Issue:2

    Topics: Animals; Antigens, Neoplasm; Cell Fractionation; Cell-Free System; Chromatography, DEAE-Cellulose; F

1973
Tumor regression mediated by Mycobacterium bovis (strain BCG). Effects of isonicotinic acid hydrazide, cortisone acetate, and antithymocyte serum.
    Journal of the National Cancer Institute, 1973, Volume: 51, Issue:1

    Topics: Animals; Antibodies, Bacterial; Antilymphocyte Serum; Cortisone; Hypersensitivity, Delayed; Isoniazi

1973
Tumor-specific immunity in 3-methylcholanthrene-induced murine fibrosarcomas. I. In vivo demonstration of immunity with three preparations of soluble antigens.
    Journal of the National Cancer Institute, 1974, Volume: 53, Issue:1

    Topics: Animals; Antibody Formation; Antigens, Neoplasm; Fibrosarcoma; Graft Rejection; Hypersensitivity, De

1974
Effect of 3-methylcholanthrene on immune response and thymus weight of Buffalo strain rats.
    Journal of the National Cancer Institute, 1974, Volume: 53, Issue:6

    Topics: Animals; Antibody Formation; BCG Vaccine; Hemolytic Plaque Technique; Hypersensitivity, Delayed; Imm

1974
The effect of carcinogens on immune responses in the guinea-pig.
    British journal of experimental pathology, 1973, Volume: 54, Issue:4

    Topics: Animals; Autoimmune Diseases; Carcinogens; Guinea Pigs; Hypersensitivity, Delayed; Hypersensitivity,

1973
Proceedings: Immunologic similarities between fetal cell antigens and tumor cell antigens in guinea pigs.
    Cancer, 1974, Volume: 33, Issue:2

    Topics: Animals; Antigens, Neoplasm; Cell Membrane; Female; Fetal Proteins; Fetus; Graft Rejection; Guinea P

1974
Brief communication: preliminary studies of tolerance to contact sensitization in carcinogen-fed guinea pigs.
    Journal of the National Cancer Institute, 1972, Volume: 48, Issue:5

    Topics: Animals; Benz(a)Anthracenes; Benzopyrenes; Dermatitis, Contact; Guinea Pigs; Haptens; Hypersensitivi

1972
Macrophage migration inhibition with mouse tumor antigens: properties of serum and peritoneal cells during tumor growth and after tumor loss.
    Cellular immunology, 1972, Volume: 3, Issue:1

    Topics: Animals; Antigens, Neoplasm; Cell Migration Inhibition; Fibrosarcoma; Hypersensitivity, Delayed; Mac

1972
Demonstration of delayed hypersensitivity to soluble antigens of chemically induced tumors by inhibition of macrophage migration.
    Proceedings of the National Academy of Sciences of the United States of America, 1969, Volume: 64, Issue:4

    Topics: Animals; Antigens; Benz(a)Anthracenes; Guinea Pigs; Hypersensitivity, Delayed; Inbreeding; Macrophag

1969
Delayed cutaneous hypersensitivity reaction to tumor-specific antigens of fibrosarcoma in sensitized mice.
    Experientia, 1970, Nov-15, Volume: 26, Issue:11

    Topics: Animals; Antigens; Capillary Permeability; Fibrosarcoma; Hypersensitivity, Delayed; Liver; Methylcho

1970
Delayed hypersensitivity and transplantation immunity elicited by soluble antigens of chemically induced tumours in inbred guinea-pigs.
    Nature, 1968, Oct-19, Volume: 220, Issue:5164

    Topics: Animals; Antigens; Benz(a)Anthracenes; Fetus; Guinea Pigs; Hypersensitivity, Delayed; Inbreeding; Ki

1968
Delayed hypersensitivity to chemically induced tumors in mice and correlation with an in vitro test.
    Journal of the National Cancer Institute, 1969, Volume: 43, Issue:1

    Topics: Animals; Antigens; Cell Movement; Culture Techniques; Foot; Freund's Adjuvant; Hypersensitivity, Del

1969