3-methylcholanthrene has been researched along with Delayed Effects, Prenatal Exposure in 10 studies
Methylcholanthrene: A carcinogen that is often used in experimental cancer studies.
3-methylcholanthrene : A pentacyclic ortho- and peri-fused polycyclic arene consisting of a dihydrocyclopenta[ij]tetraphene ring system with a methyl substituent at the 3-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To test the hypothesis that mice exposed prenatally to diethylstilbestrol (DES) develop adenocarcinomas due to sensitivity of vaginal and cervical adenosis to carcinogens, sponges impregnated with methylcholanthrene (MCA) were lodged against the cervix and vaginal fornices of 6-month-old strain CD-1 mice exposed prenatally to DES." | 3.67 | Vaginal tumors in mice from methylcholanthrene and prenatal exposure to diethylstilbestrol. ( Walker, BE, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (20.00) | 18.7374 |
| 1990's | 4 (40.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xu, Q | 1 |
| Hu, L | 1 |
| Miao, W | 1 |
| Fu, Z | 1 |
| Jin, Y | 1 |
| Moriguchi, T | 1 |
| Motohashi, H | 1 |
| Hosoya, T | 1 |
| Nakajima, O | 1 |
| Takahashi, S | 1 |
| Ohsako, S | 1 |
| Aoki, Y | 1 |
| Nishimura, N | 1 |
| Tohyama, C | 1 |
| Fujii-Kuriyama, Y | 1 |
| Yamamoto, M | 1 |
| Johri, A | 1 |
| Yadav, S | 1 |
| Dhawan, A | 1 |
| Parmar, D | 1 |
| Soyka, LF | 1 |
| Wessner, LL | 2 |
| Fan, M | 1 |
| Schaeffer, DO | 1 |
| McEntee, MF | 2 |
| Miller, MS | 5 |
| Leone-Kabler, S | 4 |
| D'Agostino, RB | 1 |
| Rollins, LA | 2 |
| O'Sullivan, MG | 2 |
| Gressani, KM | 2 |
| Cline, JM | 1 |
| Townsend, AJ | 1 |
| Malkinson, AM | 1 |
| Walker, BE | 1 |
1 review available for 3-methylcholanthrene and Delayed Effects, Prenatal Exposure
| Article | Year |
|---|---|
Differential sensitivity to lung tumorigenesis following transplacental exposure of mice to polycyclic hydrocarbons, heterocyclic amines, and lung tumor promoters.
Topics: Adenocarcinoma; Adenoma; Animals; Aryl Hydrocarbon Hydroxylases; Butylated Hydroxytoluene; Carcinoge | 2000 |
9 other studies available for 3-methylcholanthrene and Delayed Effects, Prenatal Exposure
| Article | Year |
|---|---|
Parental exposure to 3-methylcholanthrene before gestation adversely affected the endocrine system and spermatogenesis in male F1 offspring.
Topics: Adult; Animals; Endocrine System; Female; Humans; Male; Methylcholanthrene; Mice; Pregnancy; Prenata | 2022 |
Distinct response to dioxin in an arylhydrocarbon receptor (AHR)-humanized mouse.
Topics: Animals; Base Sequence; Dioxins; DNA Primers; Female; Humans; Kidney; Methylcholanthrene; Mice; Mice | 2003 |
Responsiveness of cerebral and hepatic cytochrome P450s in rat offspring prenatally exposed to lindane.
Topics: Animals; Animals, Newborn; Behavior, Animal; Brain; Cytochrome P-450 Enzyme System; Enzyme Induction | 2008 |
Hepatic drug metabolizing enzyme activity and tumorigenesis in mice following perinatal exposure to benzo(a)pyrene.
Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Body Weight; Female; Gestational Age; Leukemia L1210; Liver; | 1980 |
Mouse lung tumors exhibit specific Ki-ras mutations following transplacental exposure to 3-methylcholanthrene.
Topics: Animals; Base Sequence; Body Weight; Carcinogens; Crosses, Genetic; Cytochrome P-450 CYP1A1; Cytochr | 1996 |
Ki-ras mutations are an early event and correlate with tumor stage in transplacentally-induced murine lung tumors.
Topics: Animals; Blotting, Northern; Carcinogens; Cytochrome P-450 CYP1A1; Female; Genes, ras; Lung Neoplasm | 1997 |
Role of tumor suppressor genes in transplacental lung carcinogenesis.
Topics: Adenocarcinoma; Animals; Carcinogens; Cyclin-Dependent Kinase Inhibitor p16; Exons; Female; Genes, p | 1998 |
Induction of mutations in Ki-ras and INK4a in liver tumors of mice exposed in utero to 3-methylcholanthrene.
Topics: Animals; Carcinogens; Cyclin-Dependent Kinase Inhibitor p16; DNA Primers; Female; Genes, ras; Liver | 1998 |
Vaginal tumors in mice from methylcholanthrene and prenatal exposure to diethylstilbestrol.
Topics: Adenocarcinoma; Animals; Carcinoma, Squamous Cell; Diethylstilbestrol; Female; Fetus; Methylcholanth | 1988 |