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3-methylcholanthrene and Cocarcinogenesis

3-methylcholanthrene has been researched along with Cocarcinogenesis in 54 studies

Methylcholanthrene: A carcinogen that is often used in experimental cancer studies.
3-methylcholanthrene : A pentacyclic ortho- and peri-fused polycyclic arene consisting of a dihydrocyclopenta[ij]tetraphene ring system with a methyl substituent at the 3-position.

Cocarcinogenesis: The combination of two or more different factors in the production of cancer.

Research

Studies (54)

TimeframeStudies, this research(%)All Research%
pre-199036 (66.67)18.7374
1990's10 (18.52)18.2507
2000's7 (12.96)29.6817
2010's1 (1.85)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zeidler-Erdely, PC1
Meighan, TG1
Erdely, A1
Battelli, LA1
Kashon, ML1
Keane, M1
Antonini, JM1
Hayashi, K1
Sasaki, K1
Asada, S1
Tsuchiya, T1
Hayashi, M1
Yoshimura, I1
Tanaka, N1
Umeda, M1
Liu, WB1
Liu, JY1
Ao, L1
Zhou, ZY1
Zhou, YH1
Cui, ZH1
Yang, H1
Cao, J1
Laaksonen, M2
Mäki-Paakkanen, J2
Kronberg, L1
Komulainen, H2
Krelin, Y1
Voronov, E1
Dotan, S1
Elkabets, M1
Reich, E1
Fogel, M1
Huszar, M1
Iwakura, Y1
Segal, S2
Dinarello, CA1
Apte, RN1
Rastogi, S1
Shukla, Y1
Paul, BN1
Chowdhuri, DK1
Khanna, SK1
Das, M1
Traul, KA1
Hink, RJ1
Kachevsky, V1
Wolff, JS1
Mossman, BT3
Craighead, JE3
Clayson, DB1
Warshawsky, D1
Bingham, E1
Niemeier, RW1
Lupulescu, A3
Scribner, JD1
Scribner, NK1
Bhisey, RA3
Ramchandani, AG2
Iyengar, B2
Borges, A1
Sirsat, SM2
Frazelle, JH1
Abernethy, DJ1
Boreiko, CJ2
Mordan, LJ1
Bergin, LM1
Budnick, JE1
Meegan, RR1
Bertram, JS1
Kalland, T1
Forsberg, JG1
Liu, MQ1
Yu, LY1
Shu, QB1
Berberian, I1
Chen, LC1
Robinson, FR1
Glauert, HP1
Chow, CK1
Robertson, LW2
Perocco, P1
Paolini, M1
Mazzullo, M1
Biagi, GL1
Cantelli-Forti, G1
Sakai, A1
Tatematsu, M1
Nakanishi, K1
Murasaki, G1
Miyata, Y1
Hirose, M1
Ito, N1
Nowinski, RC1
Miller, EC1
Sivak, A1
Levin, W1
Buening, MK1
Wood, AW1
Chang, RL1
Thakker, DR1
Jerina, DM1
Conney, AH1
Shimkin, MB1
Stoner, GD1
Theiss, JC1
Mondal, S1
Brankow, DW1
Heidelberger, C1
Hassan, Y2
Priel, E2
Huleihel, M2
Aboud, M2
Bussiere, JL1
Exon, JH1
Mather, GG1
Sugezawa, A1
Kaibara, N2
Sun, Y3
Chen, CC1
Wells, RL1
Elkind, MM1
Semba, M2
Inui, N2
Male, R1
Lillehaug, JR1
Djurhuus, R1
Pryme, IF1
Borges, AM1
Chen, MH1
Zhang, YX1
Xiao, H1
Liu, HY1
Chen, X1
Zeng, Y1
Wang, ZY1
Khan, WA1
Bickers, DR1
Mukhtar, H1
Buchmann, A1
Kunz, W1
Wolf, CR1
Oesch, F1
Kawasumi, H1
Koga, S1
Hirose, R2
Hori, M2
Fujita, K2
Yamashiro, K2
Shukuwa, T2
Yoshida, H2
Rosner, K1
Herschman, HR1
Brankow, D1
Lupulescu, AP1
Welsch, CW1
Toriyama, F1
Toyoshima, H1
Ishikawa, M1
Oikawa, T1
Hosokawa, M1
Hamada, J1
Morikawa, K1
Kobayashi, H1

Reviews

3 reviews available for 3-methylcholanthrene and Cocarcinogenesis

ArticleYear
Co-carcinogenesis.
    Acta pharmacologica et toxicologica, 1984, Volume: 55 Suppl 2

    Topics: Animals; Carcinogens; Cell Division; Cocarcinogenesis; DNA; DNA Repair; Methylcholanthrene; Neoplasm

1984
Cocarcinogenesis.
    Biochimica et biophysica acta, 1979, Feb-04, Volume: 560, Issue:1

    Topics: 2-Acetylaminofluorene; Animals; Carcinogens; Cell Transformation, Viral; Cocarcinogenesis; Diet; Gas

1979
Host factors affecting the growth of carcinogen-induced rat mammary carcinomas: a review and tribute to Charles Brenton Huggins.
    Cancer research, 1985, Volume: 45, Issue:8

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenal Cortex Hormones; Animals; Antioxidants; Ascorbic Acid; Cas

1985

Other Studies

51 other studies available for 3-methylcholanthrene and Cocarcinogenesis

ArticleYear
Lung tumor promotion by chromium-containing welding particulate matter in a mouse model.
    Particle and fibre toxicology, 2013, Sep-05, Volume: 10

    Topics: Air Pollutants, Occupational; Animals; Chromium; Cocarcinogenesis; Lung Neoplasms; Male; Methylchola

2013
Technical modification of the Balb/c 3T3 cell transformation assay: the use of serum-reduced medium to optimise the practicability of the protocol.
    Alternatives to laboratory animals : ATLA, 2008, Volume: 36, Issue:6

    Topics: Animal Testing Alternatives; Animals; BALB 3T3 Cells; Carcinogenicity Tests; Carcinogens; Cattle; Ce

2008
Dynamic changes in DNA methylation during multistep rat lung carcinogenesis induced by 3-methylcholanthrene and diethylnitrosamine.
    Toxicology letters, 2009, Aug-25, Volume: 189, Issue:1

    Topics: Animals; Azacitidine; Cell Line; Cocarcinogenesis; Cyclin-Dependent Kinase Inhibitor p15; Cyclin-Dep

2009
Effects of chlorohydroxyfuranones on 3-methylcholanthrene-induced neoplastic transformation in the two-stage transformation assay in C3H 10T1/2 cells.
    Archives of toxicology, 2003, Volume: 77, Issue:10

    Topics: Animals; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cocarcinogenesis; Furans; Methylch

2003
Interleukin-1beta-driven inflammation promotes the development and invasiveness of chemical carcinogen-induced tumors.
    Cancer research, 2007, Feb-01, Volume: 67, Issue:3

    Topics: Animals; Carcinogens; Cocarcinogenesis; Female; Fibrosarcoma; Inflammation; Interleukin 1 Receptor A

2007
Protective effect of Ocimum sanctum on 3-methylcholanthrene, 7,12-dimethylbenz(a)anthracene and aflatoxin B1 induced skin tumorigenesis in mice.
    Toxicology and applied pharmacology, 2007, Nov-01, Volume: 224, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Aflatoxin B1; Animals; Anticarcinogenic A

2007
Two-stage carcinogenesis in vitro: transformation of 3-methylcholanthrene-initiated Rauscher murine leukemia virus-infected rat embryo cells by diverse tumor promoters.
    Journal of the National Cancer Institute, 1981, Volume: 66, Issue:1

    Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured;

1981
Comparative cocarcinogenic effects of crocidolite asbestos, hematite, kaolin and carbon in implanted tracheal organ cultures.
    The Annals of occupational hygiene, 1982, Volume: 26, Issue:1-4

    Topics: Animals; Asbestos; Asbestos, Crocidolite; Carbon; Cells, Cultured; Cocarcinogenesis; Cricetinae; Dus

1982
The effects of a cocarcinogen, ferric oxide, on the metabolism of benzo[a]pyrene in the isolated perfused lung.
    Journal of toxicology and environmental health, 1984, Volume: 14, Issue:2-3

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Benzo(a)pyrene; Benzopyrenes; Biotransf

1984
Tumorigenic potential of endoperoxide analogs.
    Experientia, 1984, Feb-15, Volume: 40, Issue:2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Carcinoma, Squamous Cel

1984
Is the initiation-promotion regimen in mouse skin relevant to complete carcinogenesis?
    Carcinogenesis; a comprehensive survey, 1982, Volume: 7

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Carcinogens; Cocarcinogenesis; Methyl

1982
12-0-Tetradecanoylphorbol-13-acetate-induced amplification of mesenchymal tumorigenesis in the mouse skin.
    Journal of cancer research and clinical oncology, 1983, Volume: 105, Issue:1

    Topics: Animals; Cocarcinogenesis; Female; Methylcholanthrene; Mice; Mice, Inbred Strains; Phorbols; Sarcoma

1983
Weak promotion of C3H/10T1/2 cell transformation by repeated treatments with formaldehyde.
    Cancer research, 1983, Volume: 43, Issue:7

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cocarcinogenesis; Embryo, Mammalian; Formaldehy

1983
Effect of the active tumor promoter, 12-O-tetradecanoylphorbol-13-acetate on hair follicular growth and development of hair anlage tumors in the mouse skin: a comparison with human adnexal lesions.
    Journal of cancer research and clinical oncology, 1982, Volume: 102, Issue:3

    Topics: Animals; Cocarcinogenesis; Epidermis; Female; Hair; Humans; Hyperplasia; Methylcholanthrene; Mice; P

1982
Isolation of methylcholanthrene-"initiated" C3H/10T1/2 cells by inhibiting neoplastic progression with retinyl acetate.
    Carcinogenesis, 1982, Volume: 3, Issue:3

    Topics: Animals; Cell Line; Cell Separation; Cell Transformation, Neoplastic; Cocarcinogenesis; Contact Inhi

1982
Natural killer cell activity and tumor susceptibility in female mice treated neonatally with diethylstilbestrol.
    Cancer research, 1981, Volume: 41, Issue:12 Pt 1

    Topics: Animals; Animals, Newborn; Cocarcinogenesis; Cytotoxicity, Immunologic; Diethylstilbestrol; Female;

1981
[Effect of superoxide dismutase and diethyldithiocarbamate on the induction of squamous cell carcinoma of lung with methylcholanthrene in rats].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 1994, Volume: 16, Issue:4

    Topics: Animals; Carcinoma, Squamous Cell; Cocarcinogenesis; Ditiocarb; Drug Synergism; Female; Lung Neoplas

1994
Effect of dietary retinyl palmitate on the promotion of altered hepatic foci by 3,3',4,4'-tetrachlorobiphenyl and 2,2',4,4',5,5'-hexachlorobiphenyl in rats initiated with diethylnitrosamine.
    Carcinogenesis, 1995, Volume: 16, Issue:2

    Topics: Animals; Body Weight; Cell Division; Cocarcinogenesis; Diethylnitrosamine; Diterpenes; Drug Interact

1995
beta-carotene as enhancer of cell transforming activity of powerful carcinogens and cigarette-smoke condensate on BALB/c 3T3 cells in vitro.
    Mutation research, 1999, Mar-15, Volume: 440, Issue:1

    Topics: 3T3 Cells; Animals; Benzo(a)pyrene; beta Carotene; Carcinogens; Cell Survival; Cell Transformation,

1999
p-Nonylphenol acts as a promoter in the BALB/3T3 cell transformation.
    Mutation research, 2001, Jun-27, Volume: 493, Issue:1-2

    Topics: 3T3 Cells; Animals; Carcinogens; Cell Transformation, Neoplastic; Cocarcinogenesis; Environmental Po

2001
Enhancement of 3-methylcholanthrene-induced neoplastic transformation by 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone in the two-stage transformation assay in C3H 10T1/2 cells.
    Archives of toxicology, 2001, Volume: 75, Issue:10

    Topics: Animals; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cocarcinogenesis; Fibroblasts; Fur

2001
Enhancing effect of inducers of liver microsomal enzymes on induction of hyperplastic liver nodules by N-2-fluorenylacetamide in rats.
    Journal of the National Cancer Institute, 1979, Volume: 63, Issue:6

    Topics: 2-Acetylaminofluorene; Animals; Cocarcinogenesis; Enzyme Induction; Hyperplasia; Liver; Liver Neopla

1979
Endogenous oncornaviruses in chemically induced transformation. II. Effect of virus production in vivo.
    Journal of the National Cancer Institute, 1976, Volume: 57, Issue:6

    Topics: Animals; Cocarcinogenesis; Crosses, Genetic; Female; Leukemia Virus, Murine; Male; Methylcholanthren

1976
Tumorigenic activity of 3-methylcholanthrene metabolites on mouse skin and in newborn mice.
    Cancer research, 1979, Volume: 39, Issue:9

    Topics: Administration, Topical; Animals; Animals, Newborn; Carcinogens; Cocarcinogenesis; Drug Administrati

1979
Use of hamster tracheal organ cultures for assessing the cocarcinogenic effects of inorganic particulates on the respiratory epithelium.
    Progress in experimental tumor research, 1979, Volume: 24

    Topics: Animals; Asbestos; Cocarcinogenesis; Cricetinae; Epithelium; Female; Ferric Compounds; Mesocricetus;

1979
Carcinoma induction by 3-methylcholanthrene in hamster tracheal tissue implanted in syngeneic animals.
    Progress in experimental tumor research, 1979, Volume: 24

    Topics: Adenocarcinoma; Animals; Asbestos; Carcinoma; Cocarcinogenesis; Cricetinae; Cysts; Epithelium; Femal

1979
Lung tumor response in mice to metals and metal salts.
    Advances in experimental medicine and biology, 1977, Volume: 91

    Topics: Animals; Cocarcinogenesis; Injections, Intraperitoneal; Lead; Lung Neoplasms; Manganese Poisoning; M

1977
Enhancement of carcinogenesis by prostaglandins.
    Nature, 1978, Apr-13, Volume: 272, Issue:5654

    Topics: Animals; Carcinoma, Squamous Cell; Cocarcinogenesis; DNA, Neoplasm; Methylcholanthrene; Mice; Neopla

1978
Effect of prostaglandins on skin tumorigenesis.
    Experientia, 1978, Jun-15, Volume: 34, Issue:6

    Topics: Animals; Carcinoma, Squamous Cell; Cocarcinogenesis; Male; Methylcholanthrene; Mice; Prostaglandins

1978
Enhancement of oncogenesis in C3H/10T1/2 mouse embryo cell cultures by saccharin.
    Science (New York, N.Y.), 1978, Sep-22, Volume: 201, Issue:4361

    Topics: Animals; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cocarcinogenesis; Embryo, Mammalia

1978
Chemical-retroviral cooperative carcinogenesis and its molecular basis in NIH/3T3 cells.
    Carcinogenesis, 1990, Volume: 11, Issue:12

    Topics: Animals; Cell Fusion; Cell Line; Cell Transformation, Neoplastic; Cocarcinogenesis; DNA Probes; Elec

1990
Effects of bromocriptine treatment on immune responses and 3-methylcholanthrene-induced tumorigenesis in rats.
    Immunopharmacology and immunotoxicology, 1991, Volume: 13, Issue:1-2

    Topics: Animals; Bromocriptine; Cocarcinogenesis; Drug Synergism; Immune System; Immunosuppressive Agents; I

1991
Possible mechanism for the cocarcinogenic effect of bile acids: increased intracellular uptake of methylcholanthrene by C3H/10T1/2 fibroblasts in vitro.
    Oncology, 1991, Volume: 48, Issue:2

    Topics: Animals; Bile Acids and Salts; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Coca

1991
[Effect of human semen and vaginal bacteria culture fluid on induction of cervical cancer in mice].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 1990, Volume: 12, Issue:6

    Topics: Animals; Bacillus; Carcinoma, Squamous Cell; Cervix Uteri; Cocarcinogenesis; Female; Humans; Male; M

1990
Additivity of cytotoxic damage due to dimethylbenz(a)anthracene and X rays.
    Radiation research, 1990, Volume: 123, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Line; Cell Survival; Cocarcinogenesis; Methylcholant

1990
Inhibition of 12-O-tetradecanoylphorbol-13-acetate-enhanced transformation in vitro by inhibitors of phospholipid metabolism.
    Toxicology letters, 1990, Volume: 51, Issue:1

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cocarcinogenesis; Dose-Response Relationship, D

1990
Effects of activators and inhibitors of protein kinase C on two-stage transformation in BALB/3T3 cells.
    Toxicology letters, 1990, Volume: 51, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Cell Line; Cell Transformation, N

1990
In vitro transformation and tumor promotion studies of styrene and styrene oxide.
    Carcinogenesis, 1985, Volume: 6, Issue:9

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Choline; Cocarcinogenesis; DNA; Endoplasmic Ret

1985
Influence of short-term topical exposure to phorbol ester tumor promoters on subcutaneously induced skin tumorigenesis in S/RVCri mice.
    Neoplasma, 1989, Volume: 36, Issue:3

    Topics: Animals; Cocarcinogenesis; Female; Methylcholanthrene; Mice; Mice, Inbred Strains; Phorbol Esters; S

1989
[Promoting effect of the Chinese medicinal herb, wikstroemia chamaedaphne and tung oil extracts on carcinoma of the uterine cervix induced by HSV-2 or methylcholanthrene (MCA) in mice].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 1987, Volume: 9, Issue:5

    Topics: Animals; Carcinoma, Squamous Cell; Cocarcinogenesis; Drugs, Chinese Herbal; Female; Methylcholanthre

1987
Protection against polycyclic aromatic hydrocarbon-induced skin tumor initiation in mice by green tea polyphenols.
    Carcinogenesis, 1989, Volume: 10, Issue:2

    Topics: Animals; Cocarcinogenesis; Female; Flavonoids; Methylcholanthrene; Mice; Mice, Inbred BALB C; Phenol

1989
[An experimental study of the promoting effects of extracts from Chinese medicinal herbs and tung oil (HHPA)].
    Zhonghua bing li xue za zhi = Chinese journal of pathology, 1986, Volume: 15, Issue:1

    Topics: Animals; Cocarcinogenesis; Female; Medicine, Chinese Traditional; Methylcholanthrene; Mice; Phorbol

1986
Polychlorinated biphenyls, classified as either phenobarbital- or 3-methylcholanthrene-type inducers of cytochrome P-450, are both hepatic tumor promoters in diethylnitrosamine-initiated rats.
    Cancer letters, 1986, Volume: 32, Issue:3

    Topics: Animals; Cocarcinogenesis; Cytochrome P-450 Enzyme System; Diethylnitrosamine; Enzyme Induction; Fem

1986
Cocarcinogenic activity of bile acids in the chemical transformation of C3H/10T1/2 fibroblasts in vitro.
    Oncology, 1988, Volume: 45, Issue:3

    Topics: Animals; Bile Acids and Salts; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cocarcinogen

1988
[Influences of polychlorinated dibenzofuran on carcinogenesis].
    Fukuoka igaku zasshi = Hukuoka acta medica, 1987, Volume: 78, Issue:5

    Topics: Animals; Benzofurans; Cocarcinogenesis; Methylcholanthrene; Mice; Polymers; Skin; Skin Neoplasms

1987
Effect of Moloney murine leukemia virus on the carcinogenicity of 3-methylcholanthrene in normal rat kidney cells.
    Archives of virology, 1986, Volume: 90, Issue:1-2

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cocarcinogenesis; K

1986
Interaction of epidermal growth factor with initiators and complete carcinogens in the C3H10T1/2 cell culture system.
    Journal of cellular biochemistry, 1985, Volume: 28, Issue:1

    Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; Epidermal

1985
Effect of prolonged insulin treatment on carcinoma formation in mice.
    Cancer research, 1985, Volume: 45, Issue:7

    Topics: Animals; Carcinoma, Squamous Cell; Cocarcinogenesis; DNA; Insulin; Male; Methylcholanthrene; Mice; M

1985
[Influences of polychlorinated biphenyl's (PCB) and PCB-like chemicals on 20-methylcholanthrene-induced mouse skin carcinogenesis].
    Fukuoka igaku zasshi = Hukuoka acta medica, 1985, Volume: 76, Issue:5

    Topics: Administration, Oral; Administration, Topical; Animals; Biphenyl Compounds; Carcinoma, Squamous Cell

1985
Enhancing effect of quercetin on 3-methylcholanthrene carcinogenesis in C57Bl/6 mice.
    Neoplasma, 1985, Volume: 32, Issue:4

    Topics: Animals; Bone Marrow Cells; Cocarcinogenesis; Female; Flavonoids; Lung Neoplasms; Methylcholanthrene

1985
Mechanistic aspects of initiation and promotion in C3H/10T1/2 cells.
    Carcinogenesis; a comprehensive survey, 1985, Volume: 9

    Topics: Animals; Cell Communication; Cell Line; Cell Transformation, Neoplastic; Cocarcinogenesis; Embryo, M

1985