3-methylcholanthrene has been researched along with Cataract, Membranous in 5 studies
Methylcholanthrene: A carcinogen that is often used in experimental cancer studies.
3-methylcholanthrene : A pentacyclic ortho- and peri-fused polycyclic arene consisting of a dihydrocyclopenta[ij]tetraphene ring system with a methyl substituent at the 3-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Acetaminophen can be enzymatically bioactivated, which may play a role in cataractogenesis." | 7.67 | Pharmacological studies on the in vivo cataractogenicity of acetaminophen in mice and rabbits. ( Avaria, M; Basu, PK; Lubek, BM; Wells, PG, 1988) |
| "Acetaminophen has been shown to be cataractogenic in mice and rabbits." | 7.67 | Metabolic evidence for the involvement of enzymatic bioactivation in the cataractogenicity of acetaminophen in genetically susceptible (C57BL/6) and resistant (DBA/2) murine strains. ( Basu, PK; Lubek, BM; Wells, PG, 1988) |
| " Cataract formation was induced in vitro by incubation in high-glucose solutions and in vivo by acetaminophen toxicity." | 3.73 | Accelerated cataract formation and reduced lens epithelial water permeability in aquaporin-1-deficient mice. ( Ruiz-Ederra, J; Verkman, AS, 2006) |
| "Acetaminophen can be enzymatically bioactivated, which may play a role in cataractogenesis." | 3.67 | Pharmacological studies on the in vivo cataractogenicity of acetaminophen in mice and rabbits. ( Avaria, M; Basu, PK; Lubek, BM; Wells, PG, 1988) |
| "Acetaminophen has been shown to be cataractogenic in mice and rabbits." | 3.67 | Metabolic evidence for the involvement of enzymatic bioactivation in the cataractogenicity of acetaminophen in genetically susceptible (C57BL/6) and resistant (DBA/2) murine strains. ( Basu, PK; Lubek, BM; Wells, PG, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (80.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ruiz-Ederra, J | 1 |
| Verkman, AS | 1 |
| Shichi, H | 1 |
| Gaasterland, DE | 1 |
| Jensen, NM | 1 |
| Nebert, DW | 1 |
| Ryan, AJ | 1 |
| Lubek, BM | 2 |
| Avaria, M | 1 |
| Basu, PK | 2 |
| Wells, PG | 2 |
5 other studies available for 3-methylcholanthrene and Cataract, Membranous
| Article | Year |
|---|---|
Accelerated cataract formation and reduced lens epithelial water permeability in aquaporin-1-deficient mice.
Topics: Acetaminophen; Animals; Aquaporin 1; Body Water; Cataract; Drug Combinations; Epithelial Cells; Fluo | 2006 |
Ah locus: genetic differences in susceptibility to cataracts induced by acetaminophen.
Topics: Acetaminophen; Animals; Aryl Hydrocarbon Hydroxylases; Cataract; Enzyme Induction; Methylcholanthren | 1978 |
In a mouse's eye.
Topics: Acetaminophen; Animals; Aryl Hydrocarbon Hydroxylases; Cataract; Humans; Methylcholanthrene; Mice; M | 1978 |
Pharmacological studies on the in vivo cataractogenicity of acetaminophen in mice and rabbits.
Topics: Acetaminophen; Animals; Cataract; Chemical and Drug Induced Liver Injury; Male; Methylcholanthrene; | 1988 |
Metabolic evidence for the involvement of enzymatic bioactivation in the cataractogenicity of acetaminophen in genetically susceptible (C57BL/6) and resistant (DBA/2) murine strains.
Topics: Acetaminophen; Animals; Biotransformation; Cataract; Cytochrome P-450 CYP1A2; Cytochromes; Glucurona | 1988 |