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3-methylcholanthrene and Cardiac Hypertrophy

3-methylcholanthrene has been researched along with Cardiac Hypertrophy in 1 studies

Methylcholanthrene: A carcinogen that is often used in experimental cancer studies.
3-methylcholanthrene : A pentacyclic ortho- and peri-fused polycyclic arene consisting of a dihydrocyclopenta[ij]tetraphene ring system with a methyl substituent at the 3-position.

Cardiac Hypertrophy: Enlargement of the HEART due to chamber HYPERTROPHY, an increase in wall thickness without an increase in the number of cells (MYOCYTES, CARDIAC). It is the result of increase in myocyte size, mitochondrial and myofibrillar mass, as well as changes in extracellular matrix.

Research Excerpts

ExcerptRelevanceReference
"There is a strong correlation between cytochrome P450 (P450)-dependent arachidonic acid metabolism and the pathogenesis of cardiac hypertrophy."3.753-methylcholanthrene and benzo(a)pyrene modulate cardiac cytochrome P450 gene expression and arachidonic acid metabolism in male Sprague Dawley rats. ( Aboutabl, ME; El-Kadi, AO; Zordoky, BN, 2009)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Aboutabl, ME1
Zordoky, BN1
El-Kadi, AO1

Other Studies

1 other study available for 3-methylcholanthrene and Cardiac Hypertrophy

ArticleYear
3-methylcholanthrene and benzo(a)pyrene modulate cardiac cytochrome P450 gene expression and arachidonic acid metabolism in male Sprague Dawley rats.
    British journal of pharmacology, 2009, Volume: 158, Issue:7

    Topics: Animals; Arachidonic Acid; Benzo(a)pyrene; Cardiomegaly; Chromatography, Liquid; Cytochrome P-450 En

2009