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3-methylcholanthrene and Cancer, Radiation-Induced

3-methylcholanthrene has been researched along with Cancer, Radiation-Induced in 43 studies

Methylcholanthrene: A carcinogen that is often used in experimental cancer studies.
3-methylcholanthrene : A pentacyclic ortho- and peri-fused polycyclic arene consisting of a dihydrocyclopenta[ij]tetraphene ring system with a methyl substituent at the 3-position.

Research Excerpts

ExcerptRelevanceReference
" We investigated murine soft tissue sarcomas generated by oncogenic alterations (KrasG12D activation and p53 deletion), carcinogens (3-methylcholanthrene [MCA] or ionizing radiation), and in a novel model combining both factors (MCA plus p53 deletion)."3.91Mutational landscape in genetically engineered, carcinogen-induced, and radiation-induced mouse sarcoma. ( Caraballo, I; Daniel, AR; Delaney, JR; Gresham, J; Kirsch, DG; Lee, CL; Luo, L; Mowery, YM; Owzar, K; Qin, X; Sibley, AB; Van Mater, D; Wang, X; Wisdom, AJ; Zhang, D, 2019)

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-199037 (86.05)18.7374
1990's3 (6.98)18.2507
2000's2 (4.65)29.6817
2010's1 (2.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lee, CL1
Mowery, YM1
Daniel, AR1
Zhang, D1
Sibley, AB1
Delaney, JR1
Wisdom, AJ1
Qin, X1
Wang, X1
Caraballo, I1
Gresham, J1
Luo, L1
Van Mater, D1
Owzar, K1
Kirsch, DG1
Tawara, I1
Take, Y1
Uenaka, A1
Noguchi, Y1
Nakayama, E1
ONG, SG1
HORIE, K1
MALLARD, JR1
KENT, M1
Wang, J1
Sakurai, T1
Koyama, S1
Komatubara, Y1
Suzuki, Y1
Taki, M1
Miyakoshi, J1
Doell, RG1
De Vaux St Cyr, C1
Grabar, P1
Feit, J1
Svejda, J1
Sochorová, M1
Shellabarger, CJ2
Roberts, LK2
Spellman, CW1
Daynes, RA3
Lynch, DH1
Jessup, JM1
Kahan, BD1
LeGrue, SJ1
Rutzky, L1
Pellis, NR1
Gao, FM1
Warren, S1
Brown, CE1
Chute, RN1
Federman, M1
Van Waes, C1
Monach, PA1
Urban, JL1
Wortzel, RD1
Schreiber, H3
Fortner, GW1
Kripke, ML2
Hamilton, JM1
Brouty-Boyé, D1
Gresser, I1
Baldwin, C1
Quéval, P1
Beaumatin, J1
Morin, M1
Courtois, D1
Lafuma, J1
Zackheim, HS1
Kim, JH1
Alfieri, AA1
Kim, SH1
Hong, SS1
Keszeghová, V1
Veselovská, Z1
Hlavayová, E1
Svec, J1
Niwa, O1
Enoki, Y1
Yokoro, K1
Ward, PL1
Rowley, DA1
Stauss, HJ1
Romerdahl, CA1
Donawho, C1
Fidler, IJ1
Burnham, DK1
Gahring, LC1
Flood, PM1
Ron, Y1
Boschetti, AE1
Moloney, WC1
Roe, FJ1
Rowson, KE1
Stonehill, EH1
Bendich, A1
Kondrat'eva, AF1
Handa, H1
Handa, J1
Koyama, M1
Dushkin, VA1
Podoprigora, GI1
Pollard, M1
Donner, M2
Hottier, D1
Burg, C2
Haddow, A1
Straub, RF1
Oth, D1
Vaillier, D1
Stewart, HL2
Timmer, J1
Hadders, HN1
Hardonk, MJ1
Koudstaal, J1
Kuschner, M1
Laskin, S1
Lum, GS1
Schreiner, AW1

Reviews

7 reviews available for 3-methylcholanthrene and Cancer, Radiation-Induced

ArticleYear
Unique tumor-specific antigens.
    Annual review of immunology, 1988, Volume: 6

    Topics: Animals; Antigens, Neoplasm; Cytotoxicity, Immunologic; Graft Rejection; Humans; Methylcholanthrene;

1988
The induction of cancer by combinations of viruses and other agents.
    International review of experimental pathology, 1968, Volume: 6

    Topics: Animals; Antigen-Antibody Reactions; Arboviruses; Avian Sarcoma Viruses; Carcinogens; Cell Transform

1968
[The combined action of ionizing radiation and carcinogens].
    Voprosy onkologii, 1969, Volume: 15, Issue:3

    Topics: Animals; Benz(a)Anthracenes; Bone Neoplasms; Carbon Tetrachloride Poisoning; Carcinogens; Carcinoma,

1969
[Brain tumors].
    Nihon rinsho. Japanese journal of clinical medicine, 1972, Volume: 30, Issue:1

    Topics: Animals; Astrocytoma; Benz(a)Anthracenes; Brain Neoplasms; Diethylstilbestrol; Ependymoma; Female; G

1972
[Germ-free animals and experimental oncology].
    Voprosy onkologii, 1972, Volume: 18, Issue:4

    Topics: Animals; Avian Sarcoma Viruses; Carcinogens; Chickens; Fibrosarcoma; Friend murine leukemia virus; G

1972
Molecular repair, wound healing, and carcinogenesis: tumor production a possible overhealing?
    Advances in cancer research, 1972, Volume: 16

    Topics: Animals; Benzopyrenes; Carcinogens; Cell Migration Inhibition; Cell Transformation, Neoplastic; Cell

1972
Experimental alimentary tract cancer.
    National Cancer Institute monograph, 1967, Volume: 25

    Topics: Animals; Cricetinae; Dogs; Gastrointestinal Neoplasms; Hydrocarbons; Methylcholanthrene; Mice; Neopl

1967

Other Studies

36 other studies available for 3-methylcholanthrene and Cancer, Radiation-Induced

ArticleYear
Mutational landscape in genetically engineered, carcinogen-induced, and radiation-induced mouse sarcoma.
    JCI insight, 2019, 07-11, Volume: 4, Issue:13

    Topics: Animals; Carcinogenesis; Carcinogens; DNA Mutational Analysis; Exome Sequencing; Genomic Instability

2019
Sequential involvement of two distinct CD4+ regulatory T cells during the course of transplantable tumor growth and protection from 3-methylcholanthrene-induced tumorigenesis by CD25-depletion.
    Japanese journal of cancer research : Gann, 2002, Volume: 93, Issue:8

    Topics: Animals; Antibodies, Monoclonal; Carcinogens; CD4-Positive T-Lymphocytes; Cell Division; Down-Regula

2002
COSMIC RADIATION AND CANCER. I. INFLUENCE OF COSMIC RADIATION AT SEA-LEVEL ON INDUCED CANCER.
    Scientia Sinica, 1963, Volume: 12

    Topics: Carcinogenesis; Cosmic Radiation; Methylcholanthrene; Mice; Neoplasms; Neoplasms, Experimental; Neop

1963
PATHOLOGICAL STUDIES ON EXPERIMENTAL BONE TUMOR.
    Acta pathologica japonica, 1964, Volume: 14

    Topics: Alkaline Phosphatase; Animals; Benzopyrenes; Bone Neoplasms; Carcinogens; Croton Oil; Histocytochemi

1964
DIFFERENCES OBSERVED BETWEEN ELECTRON SPIN RESONANCE SIGNALS FROM SURVIVING TUMOUR TISSUES AND FROM THEIR CORRESPONDING NORMAL TISSUES.
    Nature, 1964, Dec-19, Volume: 204

    Topics: Electron Spin Resonance Spectroscopy; Fibrosarcoma; Kidney; Kidney Neoplasms; Liver; Liver Neoplasms

1964
Effects of 2450 MHz electromagnetic fields with a wide range of SARs on methylcholanthrene-induced transformation in C3H10T1/2 cells.
    Journal of radiation research, 2005, Volume: 46, Issue:3

    Topics: Animals; Cell Survival; Cell Transformation, Neoplastic; Dose-Response Relationship, Radiation; Elec

2005
Immune reactivity prior to development of thymic lymphoma in C57BL mice.
    International journal of cancer, 1967, Mar-15, Volume: 2, Issue:2

    Topics: Animals; Female; Immunosuppressive Agents; Lymphoma; Male; Methylcholanthrene; Mice; Neoplasms, Radi

1967
Experimental intestinal metaplasia of gastric mucosa of rats and its relationship to carcinoma.
    Neoplasma, 1967, Volume: 14, Issue:3

    Topics: Adenocarcinoma; Animals; Metaplasia; Methylcholanthrene; Neoplasms, Radiation-Induced; Phosphorus Is

1967
Effect of 3-methylcholanthrene and x- irradiation, given singly or combined, on rat mammary carcinogenesis.
    Journal of the National Cancer Institute, 1967, Volume: 38, Issue:1

    Topics: Adenocarcinoma; Animals; Female; Mammary Neoplasms, Experimental; Methylcholanthrene; Neoplasms, Rad

1967
Modulation of immunoregulatory responses directed toward various tumor antigens within hosts possessing distinct immunologic potentials.
    Journal of immunology (Baltimore, Md. : 1950), 1980, Volume: 125, Issue:2

    Topics: Animals; Antigens, Neoplasm; Cell Transformation, Neoplastic; Epitopes; Female; Histocompatibility A

1980
Evidence for two functionally distinct cross-reactive tumor antigens associated with ultraviolet light and chemically induced tumors.
    Transplantation, 1982, Volume: 33, Issue:4

    Topics: Animals; Antigens, Neoplasm; Benzopyrenes; Cross Reactions; Cytotoxicity, Immunologic; Epitopes; Fem

1982
Soluble factors from murine and human tumors induce suppressor cells.
    The Journal of surgical research, 1984, Volume: 36, Issue:6

    Topics: Adenocarcinoma; Animals; Cell Line; Colonic Neoplasms; Dinitrochlorobenzene; Female; Fibrosarcoma; H

1984
[Induction of tumors in rats by 60 Co irradiation and intramedullary embedding of methylcholanthrene-paraffin pellet].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 1983, Volume: 5, Issue:2

    Topics: Animals; Cobalt Radioisotopes; Male; Methylcholanthrene; Neoplasms, Experimental; Neoplasms, Radiati

1983
Mesothelioma relative to asbestos, radiation, and methylcholanthrene.
    Archives of pathology & laboratory medicine, 1981, Volume: 105, Issue:6

    Topics: Animals; Asbestos; Asbestosis; Female; Lung Neoplasms; Lymphocytes; Macrophages; Male; Mesothelioma;

1981
Immunodominance deters the response to other tumor antigens thereby favoring escape: prevention by vaccination with tumor variants selected with cloned cytolytic T cells in vitro.
    Tissue antigens, 1996, Volume: 47, Issue:5

    Topics: Animals; Antigens, Neoplasm; Cancer Vaccines; Carcinogens; Clone Cells; Cytotoxicity, Immunologic; D

1996
In vitro reactivity of splenic lymphocytes from normal and UV-irradiated mice against syngeneic UV-induced tumors.
    Journal of immunology (Baltimore, Md. : 1950), 1977, Volume: 118, Issue:4

    Topics: Animals; Antigens, Neoplasm; Cross Reactions; Cytotoxicity Tests, Immunologic; Epitopes; Graft Rejec

1977
Renal carcinogenesis.
    Advances in cancer research, 1975, Volume: 22

    Topics: Aflatoxins; Animals; Anti-Bacterial Agents; Anura; Bromocriptine; Chickens; Cricetinae; Cycasin; Her

1975
Decreased sensitivity to interferon associated with in vitro transformation of X-ray-transformed C3H/10T1/2 cells.
    International journal of cancer, 1979, Volume: 24, Issue:2

    Topics: Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Clone Cells; In

1979
Inducibility of microsomal enzymes in normal and pre-cancerous lung tissue. Synergistic action of 5-6 benzoflavon or methyl-cholanthrene in radiation induced carcinogenesis.
    Biomedicine / [publiee pour l'A.A.I.C.I.G.], 1979, Volume: 31, Issue:6

    Topics: Animals; Benzoflavones; Carcinoma, Squamous Cell; Enzyme Induction; Lung; Lung Neoplasms; Male; Meth

1979
Cutaneous basal cell carcinomas in the rat.
    Journal of the National Cancer Institute, 1992, May-20, Volume: 84, Issue:10

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Basal Cell; Fibrosarcoma; Methylcholanthrene;

1992
Radiosensitization of two murine fibrosarcomas with 6-thioguanine.
    International journal of radiation oncology, biology, physics, 1990, Volume: 18, Issue:3

    Topics: Animals; Combined Modality Therapy; Dose-Response Relationship, Radiation; Fibrosarcoma; Male; Methy

1990
Expression of retrovirus-related functions in the methylcholanthrene-induced rat myelogenous leukemia.
    Neoplasma, 1985, Volume: 32, Issue:5

    Topics: Animals; Deoxyribonuclease EcoRI; DNA Restriction Enzymes; DNA-Directed DNA Polymerase; Electrophore

1985
Overexpression and amplification of the c-myc gene in mouse tumors induced by chemicals and radiations.
    Japanese journal of cancer research : Gann, 1989, Volume: 80, Issue:3

    Topics: Animals; Deoxyribonuclease EcoRI; Deoxyribonuclease HindIII; Gene Amplification; Gene Expression Reg

1989
Effect of ultraviolet-B radiation on the in vivo growth of murine melanoma cells.
    Cancer research, 1988, Jul-15, Volume: 48, Issue:14

    Topics: Animals; Cell Division; Cell Line; Cell Survival; Female; Fibrosarcoma; Melanoma; Methylcholanthrene

1988
Clonal origin of tumors induced by ultraviolet radiation.
    Journal of the National Cancer Institute, 1986, Volume: 76, Issue:1

    Topics: Animals; Benzo(a)pyrene; Female; Methylcholanthrene; Mice; Mice, Inbred C3H; Neoplasm Transplantatio

1986
Protective immunity to progressive tumors can be induced by antigen presented on regressor tumors.
    Journal of immunology (Baltimore, Md. : 1950), 1987, May-15, Volume: 138, Issue:10

    Topics: Animals; Antigens, Neoplasm; Female; Fibrosarcoma; Graft Rejection; Haptens; Immunization; Immunizat

1987
Observations on pancreatic islet cell and other radiation-induced tumors in the rat.
    Laboratory investigation; a journal of technical methods and pathology, 1966, Volume: 15, Issue:3

    Topics: Adenoma, Islet Cell; Animals; Methylcholanthrene; Neoplasms, Radiation-Induced; Rats

1966
Retrogenetic expression: the reappearance of embryonal antigens in cancer cells.
    Nature, 1970, Oct-24, Volume: 228, Issue:5269

    Topics: AKR murine leukemia virus; Animals; Antigens; Benz(a)Anthracenes; Benzopyrenes; Diethylstilbestrol;

1970
Carcinogenesis in germ-free animals.
    Progress in immunobiological standardization, 1971, Volume: 5

    Topics: AKR murine leukemia virus; Animals; Avian Sarcoma Viruses; Benz(a)Anthracenes; Cell Transformation,

1971
Factors influencing the effect of an adjuvant on the growth of solid isogeneic tumors.
    European journal of cancer, 1972, Volume: 8, Issue:2

    Topics: Adenocarcinoma; Adjuvants, Immunologic; Animals; Antibody Formation; Immunity, Cellular; Methylchola

1972
Effect of 3-methylcholanthrene and fission neutron irradiation, given singly or combined, on rat mammary carcinogenesis.
    Journal of the National Cancer Institute, 1972, Volume: 48, Issue:1

    Topics: Adenocarcinoma; Animals; Female; Mammary Neoplasms, Experimental; Methylcholanthrene; Neoplasms, Rad

1972
[In vivo quantitative analysis of immune reactions to solid murine tumors in syngeneic hosts].
    International journal of cancer, 1972, Jan-15, Volume: 9, Issue:1

    Topics: Adenocarcinoma; Animals; Antigens; Antigens, Neoplasm; Female; Immunosuppression Therapy; Male; Math

1972
Experimentally induced gastric adenocarcinomas. Maude Abbott Lecture, 1971.
    Laboratory investigation; a journal of technical methods and pathology, 1971, Volume: 25, Issue:6

    Topics: Adenocarcinoma; Aflatoxins; Animals; Anti-Bacterial Agents; Benz(a)Anthracenes; Carcinogens; Fluoren

1971
An experimental investigation into the development of callus and induced bone tumours in mice studies by histological and enzyme histochemical methods.
    British journal of cancer, 1968, Volume: 22, Issue:3

    Topics: Alkaline Phosphatase; Animals; Bone Neoplasms; Bone Regeneration; Calcium Isotopes; Female; Fibrosar

1968
Experimental models in environmental carcinogenesis.
    The American journal of pathology, 1971, Volume: 64, Issue:1

    Topics: Air Pollution; Animals; Benzopyrenes; Bronchi; Carcinogens; Carcinoma, Bronchogenic; Carcinoma, Squa

1971
Sarcomas in the wistar rat.
    Oncology, 1967, Volume: 21, Issue:2

    Topics: Animals; Methylcholanthrene; Neoplasm Transplantation; Neoplasms, Radiation-Induced; Oncogenic Virus

1967