3-methylcholanthrene has been researched along with Breast Neoplasms in 91 studies
Methylcholanthrene: A carcinogen that is often used in experimental cancer studies.
3-methylcholanthrene : A pentacyclic ortho- and peri-fused polycyclic arene consisting of a dihydrocyclopenta[ij]tetraphene ring system with a methyl substituent at the 3-position.
Breast Neoplasms: Tumors or cancer of the human BREAST.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We reported previously that 3-methylcholanthrene (3MC), an exogenous AhR agonist, inhibited tumorsphere (mammosphere) formation from breast cancer cell lines, while the endogenous AhR agonist, indirubin, very weakly inhibited this process." | 8.02 | Activation of the aryl hydrocarbon receptor by 3-methylcholanthrene, but not by indirubin, suppresses mammosphere formation via downregulation of CDC20 expression in breast cancer cells. ( Kanno, Y; Kase, A; Kizu, R; Nemoto, K; Ozawa, M; Sanada, N; Taga, C; Yamashita, N; Yoshizuka, A, 2021) |
| "Three spontaneous pulmonary adenomas of C mice, morphologically resembling those induced by methylcholanthrene or urethane, were propagated in host after host under conditions such that the neoplastic cells were directly exposed, while proliferating, to one or the other of these agents." | 7.63 | Are carcinogens responsible for the superimposed neoplastic changes occurring in mouse tumor cells? The effect of methylcholanthrene and urethane on pulmonary adenomas and of methylcholanthrene on mammary carcinomas. ( DUMBELL, K; ROUS, P, 1955) |
| "SkBr3 breast cancer cells and cancer-associated fibroblasts (CAFs) derived from breast tumor patients were used as model system." | 5.51 | AHR and GPER mediate the stimulatory effects induced by 3-methylcholanthrene in breast cancer cells and cancer-associated fibroblasts (CAFs). ( Briguori, S; Bruno, L; Cirillo, F; Di Martino, MT; Grande, F; Guzzi, R; Lappano, R; Maggiolini, M; Miglietta, AM; Nakajima, M; Rizzuti, B, 2019) |
| " We reported previously that 3-methylcholanthrene (3MC), an exogenous AhR agonist, inhibited tumorsphere (mammosphere) formation from breast cancer cell lines, while the endogenous AhR agonist, indirubin, very weakly inhibited this process." | 4.02 | Activation of the aryl hydrocarbon receptor by 3-methylcholanthrene, but not by indirubin, suppresses mammosphere formation via downregulation of CDC20 expression in breast cancer cells. ( Kanno, Y; Kase, A; Kizu, R; Nemoto, K; Ozawa, M; Sanada, N; Taga, C; Yamashita, N; Yoshizuka, A, 2021) |
| "The class-3 aldehyde dehydrogenase that is overexpressed (> 100-fold) in human breast adenocarcinoma MCF-7/0 cells made resistant (> 30-fold as judged by LC90s) to oxazaphosphorines, such as mafosfamide, by growing them in the presence of polycyclic aromatic hydrocarbons, e." | 3.69 | Identification of a methylcholanthrene-induced aldehyde dehydrogenase in a human breast adenocarcinoma cell line exhibiting oxazaphosphorine-specific acquired resistance. ( Sladek, NE; Sreerama, L, 1994) |
| "Human breast adenocarcinoma MCF-7/0 cells and a stably oxazaphosphorine-resistant subline thereof, MCF-7/OAP, were grown in the presence of 3-methylcholanthrene (3 microM), catechol (30 microM), or vehicle for 5 days." | 3.69 | Multienzyme-mediated stable and transient multidrug resistance and collateral sensitivity induced by xenobiotics. ( Rekha, GK; Sladek, NE, 1997) |
| "Three spontaneous pulmonary adenomas of C mice, morphologically resembling those induced by methylcholanthrene or urethane, were propagated in host after host under conditions such that the neoplastic cells were directly exposed, while proliferating, to one or the other of these agents." | 3.63 | Are carcinogens responsible for the superimposed neoplastic changes occurring in mouse tumor cells? The effect of methylcholanthrene and urethane on pulmonary adenomas and of methylcholanthrene on mammary carcinomas. ( DUMBELL, K; ROUS, P, 1955) |
| "SkBr3 breast cancer cells and cancer-associated fibroblasts (CAFs) derived from breast tumor patients were used as model system." | 1.51 | AHR and GPER mediate the stimulatory effects induced by 3-methylcholanthrene in breast cancer cells and cancer-associated fibroblasts (CAFs). ( Briguori, S; Bruno, L; Cirillo, F; Di Martino, MT; Grande, F; Guzzi, R; Lappano, R; Maggiolini, M; Miglietta, AM; Nakajima, M; Rizzuti, B, 2019) |
| " Dose-response studies revealed that the concentration of 3MC required to half-maximally activate transcription (EC(50)) was >100-fold higher for an ER reporter (27-57 muM) than for an AhR reporter (86-250 nM) in both MCF-7 cells and in human endometrial cancer Ishikawa cells." | 1.33 | Aryl hydrocarbon receptor-independent activation of estrogen receptor-dependent transcription by 3-methylcholanthrene. ( Shipley, JM; Waxman, DJ, 2006) |
| "No genital tract or mammary cancer occurred in mice receiving less than 2." | 1.24 | MURINE MAMMARY CARCINOMAS INDUCED BY INTRAVAGINAL APPLICATIONS OF METHYLCHOLANTHRENE IN MINIMAL DOSAGES. ( CAMPBELL, JS; YANG, YH, 1964) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 78 (85.71) | 18.7374 |
| 1990's | 5 (5.49) | 18.2507 |
| 2000's | 5 (5.49) | 29.6817 |
| 2010's | 1 (1.10) | 24.3611 |
| 2020's | 2 (2.20) | 2.80 |
| Authors | Studies |
|---|---|
| Yamashita, N | 2 |
| Yoshida, K | 1 |
| Sanada, N | 3 |
| Kanno, Y | 2 |
| Kizu, R | 3 |
| Yoshizuka, A | 1 |
| Kase, A | 1 |
| Ozawa, M | 1 |
| Taga, C | 1 |
| Nemoto, K | 1 |
| Cirillo, F | 1 |
| Lappano, R | 1 |
| Bruno, L | 1 |
| Rizzuti, B | 1 |
| Grande, F | 1 |
| Guzzi, R | 1 |
| Briguori, S | 1 |
| Miglietta, AM | 1 |
| Nakajima, M | 1 |
| Di Martino, MT | 1 |
| Maggiolini, M | 1 |
| Gotoh, Y | 1 |
| Shimazawa, R | 1 |
| Klinge, CM | 1 |
| ORR, JW | 3 |
| KIRSCHBAUM, A | 2 |
| WILLIAMS, WL | 1 |
| BITTNER, JJ | 2 |
| ANDERVONT, HB | 2 |
| DUNN, TB | 2 |
| DUMBELL, K | 1 |
| ROUS, P | 1 |
| MARCHANT, J | 8 |
| BONSER, GM | 5 |
| GRUENSTEIN, M | 6 |
| HARRIS, C | 3 |
| SHAY, H | 6 |
| HUGGINS, C | 2 |
| McCARTHY, JD | 1 |
| HARAN-GHERA, N | 2 |
| GRAND, LC | 1 |
| BRILLANTES, FP | 1 |
| DAMM, HC | 1 |
| TURNER, CW | 1 |
| DAO, TL | 5 |
| BOCK, FG | 1 |
| GREINER, MJ | 2 |
| DELLA PORTA, G | 1 |
| RANADIVE, KJ | 1 |
| HAKIM, SA | 1 |
| KHARKAR, KR | 1 |
| KIM, U | 4 |
| FURTH, J | 4 |
| YOUNG, S | 1 |
| BIANCIFIORI, C | 3 |
| CASCHERA, F | 3 |
| CLIFTON, KH | 1 |
| DANIEL, PM | 2 |
| PRICHARD, MM | 2 |
| ERCOLI, A | 1 |
| BRIZIARELLI, G | 1 |
| HAUS, E | 1 |
| HALBERG, F | 1 |
| ISHIKURA, H | 1 |
| BOLASNY, BL | 2 |
| WARREN, SE | 2 |
| PROHASKA, JV | 1 |
| SYDNOR, KL | 1 |
| COCKRELL, B | 1 |
| HELLSTROEM, KE | 1 |
| POLLARD, M | 1 |
| MOON, RC | 1 |
| ENGELBART, K | 1 |
| GERICKE, D | 1 |
| RIGDEN, MC | 1 |
| BRIGHAM, DW | 1 |
| NELSON, JS | 1 |
| HERSHEY, FB | 1 |
| SHIMKIN, MB | 3 |
| YANG, YH | 1 |
| CAMPBELL, JS | 1 |
| VANPROHASKA, J | 1 |
| REES, ED | 1 |
| MUKERJEE, D | 1 |
| OWENS, AH | 1 |
| BUSCH, GJ | 1 |
| RIGGOTT, JM | 1 |
| LAW, LW | 1 |
| CHANG, SM | 1 |
| WANG, D | 1 |
| LU, YL | 1 |
| MILLER, EW | 1 |
| PYBUS, FC | 1 |
| JULL, JW | 1 |
| CIMINERA, JL | 1 |
| LINDER, OE | 1 |
| RUDALI, G | 1 |
| RYAN, JF | 1 |
| MOCK, LF | 1 |
| BOLASNY, B | 1 |
| VAN PROHASKA, J | 1 |
| DMOCHOWSKI, L | 1 |
| Shipley, JM | 1 |
| Waxman, DJ | 1 |
| Abdelrahim, M | 2 |
| Ariazi, E | 2 |
| Kim, K | 1 |
| Khan, S | 2 |
| Barhoumi, R | 1 |
| Burghardt, R | 1 |
| Liu, S | 2 |
| Hill, D | 1 |
| Finnell, R | 1 |
| Wlodarczyk, B | 1 |
| Jordan, VC | 2 |
| Safe, S | 3 |
| Soloway, AH | 1 |
| KRISCHBAUM, A | 1 |
| Bleehen, NM | 1 |
| Bryant, TH | 1 |
| Greiner, JW | 1 |
| Malan-Shibley, LB | 1 |
| Janss, DH | 1 |
| Sreerama, L | 3 |
| Sladek, NE | 4 |
| Rekha, GK | 1 |
| Pimm, MV | 1 |
| Baldwin, RW | 1 |
| Shearer, WT | 1 |
| Fink, MP | 1 |
| Chaloupka, K | 1 |
| Krishnan, V | 1 |
| Squartini, F | 1 |
| Bistocchi, M | 1 |
| Sarnelli, R | 1 |
| Basolo, F | 1 |
| London, RS | 1 |
| Murphy, L | 1 |
| Kitlowski, KE | 1 |
| Leibowitz, S | 1 |
| Schwartz, RS | 1 |
| Angel BasombrÃo, M | 1 |
| Sodomann, CP | 1 |
| Haferkamp, O | 1 |
| Thomas, C | 1 |
| Hilf, R | 1 |
| Goldenberg, H | 1 |
| Bell, C | 1 |
| Michel, I | 1 |
| Orlando, RA | 1 |
| Archer, FL | 1 |
4 reviews available for 3-methylcholanthrene and Breast Neoplasms
| Article | Year |
|---|---|
Immune surveillance system: its failure and activation.
Topics: Aged; Animals; Antibodies; Breast Neoplasms; Cell Transformation, Neoplastic; Complement System Prot | 1977 |
Early pathologic changes in experimental and human breast cancer: facts and comments.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast; Breast Neoplasms; Cell Transformation, Neoplastic | 1986 |
Malignancy as a complication of immunosuppressive therapy.
Topics: Animals; Antibiotics, Antineoplastic; Antibody Formation; Antigens, Neoplasm; Breast Neoplasms; Burk | 1971 |
The immunology of cancer.
Topics: Animals; Antibodies, Neoplasm; Antigen-Antibody Complex; Antigens, Neoplasm; Breast Neoplasms; Colon | 1973 |
87 other studies available for 3-methylcholanthrene and Breast Neoplasms
| Article | Year |
|---|---|
Aryl Hydrocarbon Receptor Directly Regulates VTCN1 Gene Expression in MCF-7 Cells.
Topics: Basic Helix-Loop-Helix Transcription Factors; Breast Neoplasms; Female; Gene Expression; Humans; MCF | 2022 |
Activation of the aryl hydrocarbon receptor by 3-methylcholanthrene, but not by indirubin, suppresses mammosphere formation via downregulation of CDC20 expression in breast cancer cells.
Topics: Breast Neoplasms; Cdc20 Proteins; Cell Line, Tumor; Down-Regulation; Female; Gene Expression Regulat | 2021 |
AHR and GPER mediate the stimulatory effects induced by 3-methylcholanthrene in breast cancer cells and cancer-associated fibroblasts (CAFs).
Topics: Basic Helix-Loop-Helix Transcription Factors; Breast Neoplasms; Cancer-Associated Fibroblasts; Cell | 2019 |
Repression of activated aryl hydrocarbon receptor-induced transcriptional activation by 5alpha-dihydrotestosterone in human prostate cancer LNCaP and human breast cancer T47D cells.
Topics: Androgens; Aryl Hydrocarbon Hydroxylases; Basic Helix-Loop-Helix Transcription Factors; Breast Neopl | 2009 |
The induction of mammary carcinoma in IF mice by cutaneous and intraperitoneal administration of methylcholanthrene.
Topics: Animals; Breast Neoplasms; Humans; Methylcholanthrene; Mice; Neoplasms | 1946 |
Induction of mammary cancer with methylcholanthrene; histogenesis of the induced neoplasm.
Topics: Breast Neoplasms; Humans; Methylcholanthrene; Neoplasms | 1946 |
Responses of strain DBAf/2 mice, without the mammary tumor agent, to oral administration of methylcholanthrene.
Topics: Administration, Oral; Animals; Breast Neoplasms; Humans; Leukemia, Experimental; Methylcholanthrene; | 1953 |
Are carcinogens responsible for the superimposed neoplastic changes occurring in mouse tumor cells? The effect of methylcholanthrene and urethane on pulmonary adenomas and of methylcholanthrene on mammary carcinomas.
Topics: Adenoma; Animals; Breast Neoplasms; Carcinogens; Humans; Lung; Lung Neoplasms; Methylcholanthrene; M | 1955 |
Influence of pregnancy and lactation on the incidence of mammary carcinoma induced with methylcholanthrene in female mice of the "IF" strain.
Topics: Animals; Breast Feeding; Breast Neoplasms; Female; Humans; Incidence; Lactation; Methylcholanthrene; | 1955 |
The significance of morphological changes in the mouse breast during chemical carcinogenesis.
Topics: Animals; Breast Neoplasms; Carcinogenesis; Fibroadenoma; Humans; Mammary Neoplasms, Experimental; Me | 1956 |
The significance of morphological changes in the mouse breast during chemical carcinogenesis.
Topics: Animals; Breast Neoplasms; Carcinogenesis; Fibroadenoma; Humans; Mammary Neoplasms, Experimental; Me | 1956 |
The significance of morphological changes in the mouse breast during chemical carcinogenesis.
Topics: Animals; Breast Neoplasms; Carcinogenesis; Fibroadenoma; Humans; Mammary Neoplasms, Experimental; Me | 1956 |
The significance of morphological changes in the mouse breast during chemical carcinogenesis.
Topics: Animals; Breast Neoplasms; Carcinogenesis; Fibroadenoma; Humans; Mammary Neoplasms, Experimental; Me | 1956 |
Reproducibility of method and hormonal influences in induction of breast cancer in rats by gastric instillation of methylcholanthrene.
Topics: Animals; Breast Neoplasms; Humans; Mammary Neoplasms, Experimental; Methylcholanthrene; Rats; Reprod | 1956 |
Reproducibility of method and hormonal influences in induction of breast cancer in rats by gastric instillation of methylcholanthrene.
Topics: Animals; Breast Neoplasms; Humans; Mammary Neoplasms, Experimental; Methylcholanthrene; Rats; Reprod | 1956 |
Reproducibility of method and hormonal influences in induction of breast cancer in rats by gastric instillation of methylcholanthrene.
Topics: Animals; Breast Neoplasms; Humans; Mammary Neoplasms, Experimental; Methylcholanthrene; Rats; Reprod | 1956 |
Reproducibility of method and hormonal influences in induction of breast cancer in rats by gastric instillation of methylcholanthrene.
Topics: Animals; Breast Neoplasms; Humans; Mammary Neoplasms, Experimental; Methylcholanthrene; Rats; Reprod | 1956 |
Regression of human metastatic mammary cancer induced by 3-methyicholanthrene.
Topics: Breast; Breast Neoplasms; Cell Transformation, Neoplastic; Humans; Methylcholanthrene | 1957 |
The induction of breast tumours by methylcholanthrene in castrated male and female mice of the IF strain bearing ovarian grafts.
Topics: Animals; Breast Neoplasms; Castration; Female; Humans; Male; Mammary Neoplasms, Experimental; Methyl | 1958 |
Local inhibition by lactation of chemically induced breast tumours in mice of the IF strain.
Topics: Animals; Breast Feeding; Breast Neoplasms; Female; Humans; Lactation; Mammary Neoplasms, Experimenta | 1959 |
The role of mammotrophin in mammary tumor induction in mice.
Topics: Animals; Breast Neoplasms; Humans; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Methy | 1961 |
Mammary cancer induced by a single feeding of polymucular hydrocarbons, and its suppression.
Topics: Animals; Benz(a)Anthracenes; Breast Neoplasms; Cell Transformation, Neoplastic; Fluorenes; Humans; H | 1961 |
Long-term effect of estrogen and progesterone on mammary gland growth in 3-methyl-cholanthrene treated and non-treated ovariectomized rats.
Topics: Animals; Benz(a)Anthracenes; Breast; Breast Neoplasms; Castration; Estradiol; Estrogens; Female; Hum | 1961 |
Mammary carcinogenesis by 3-methylcholanthrene. II. Inhibitory effect of pregnancy and lactation on tumor induction.
Topics: Animals; Breast Feeding; Breast Neoplasms; Carcinogenesis; Female; Humans; Lactation; Mammary Neopla | 1960 |
Mammary carcinogenesis by 3-methylcholanthrene. III. Induction of mammary carcinoma and milk secretion in male rats bearing ovarian grafts.
Topics: Animals; Breast; Breast Feeding; Breast Neoplasms; Carcinogenesis; Female; Humans; Lactation; Male; | 1961 |
Spontaneous mammary cancer developing in rats born and nursed by mothers treated with 3-methylcholanthrene.
Topics: Animals; Breast Neoplasms; Female; Humans; Mammary Neoplasms, Experimental; Methylcholanthrene; Moth | 1960 |
Induction of intestinal, mammary, and ovarian tumors in hamsters with oral administration of 20-methylcholanthrene.
Topics: Administration, Oral; Animals; Breast Neoplasms; Cricetinae; Female; Humans; Intestinal Neoplasms; I | 1961 |
Chemical induction of mammary cancer in pseudopregnancy.
Topics: Animals; Breast Neoplasms; Carcinoma; Female; Humans; Mammary Neoplasms, Experimental; Methylcholant | 1960 |
Relation of mammotropes to mammary tumors. IV. Development of highly hormone-dependent mammary tumors.
Topics: Animals; Breast Neoplasms; Humans; Lactotrophs; Mammary Glands, Human; Mammary Neoplasms, Animal; Me | 1960 |
Failure of methylcholanthrene to induce breast tumours in male IF mice when administered before stimulation of the breast tissue by ovarian secretion.
Topics: Animals; Breast; Breast Neoplasms; Estrogens; Humans; Male; Mammary Neoplasms, Experimental; Methylc | 1961 |
Induction of mammary carcinoma in hypophysectomized rats treated with 3-methylcholanthrene, oestradiol-17 beta, progesterone and growth hormone.
Topics: Animals; Breast Neoplasms; Estradiol; Growth Hormone; Humans; Hypophysectomy; Mammary Neoplasms, Exp | 1961 |
The influence of pseudopregnancy on the induction of mammary tumours by methylcholanthrene in mice of the BALB/c strain.
Topics: Animals; Breast Neoplasms; Female; Humans; Mammary Neoplasms, Experimental; Methylcholanthrene; Mice | 1959 |
Relation of mammary tumors to mammotropes. III. Hormone responsiveness of transplanted mammary tumors.
Topics: Animals; Breast Neoplasms; Carcinoma; Hormones; Humans; Lactotrophs; Mammary Neoplasms, Animal; Mamm | 1960 |
Relation of mammary tumors to mammotropes. I. Induction of mammary tumors in rats.
Topics: Animals; Breast Neoplasms; Carcinoma; Lactotrophs; Mammary Neoplasms, Animal; Mammary Neoplasms, Exp | 1960 |
Relation of mammary tumors to mammotropes. II. Hormone responsiveness of 3-methylcholanthrene induced mammary carcinomas.
Topics: Animals; Breast Neoplasms; Carcinoma; Hormones; Humans; Lactotrophs; Mammary Neoplasms, Animal; Mamm | 1960 |
Chemically induced mammary tumours following unilateral excision of the nipples in pseudopregnant and lactating breeding BALB/C mice.
Topics: Animals; Breast Feeding; Breast Neoplasms; Breeding; Female; Humans; Lactation; Mammary Neoplasms, E | 1962 |
The production of mammary tumours in rats feeding with 3-methylcholanthrene.
Topics: Animals; Breast Neoplasms; Humans; Mammary Neoplasms, Experimental; Methylcholanthrene; Rats | 1961 |
Mammary carcinogenesis by 3-methylcholanthrene. IV. Effect of pituitary homograft on mammary-gland growth and tumorigenesis.
Topics: Allografts; Animals; Breast; Breast Neoplasms; Cell Transformation, Neoplastic; Humans; Mammary Neop | 1962 |
Effect of enol-ether derivatives of dihydrotestosterone on 3-methylcholanthrene-induced rat mammary carcinoma.
Topics: Animals; Breast; Breast Neoplasms; Dihydrotestosterone; Ether; Ethers; Humans; Mammary Neoplasms, Ex | 1961 |
Interactions of a chemical carcinogen with neuro-endocrine factors in mouse breast cancer.
Topics: Animals; Brain; Breast Neoplasms; Carcinogens; Fibroadenoma; Hypothalamus; Methylcholanthrene; Mice; | 1962 |
The influence of pseudopregnancy on breast tumour induction in C57BI mice by various chemical carcinogens.
Topics: Animals; Benz(a)Anthracenes; Benzopyrenes; Breast Neoplasms; Carcinogens; Female; Humans; Mammary Ne | 1963 |
The effect of olfactory lobectomy and induced pseudopregnancy on the incidence of methylcholanthrene-induced mammary and ovarian tumours in C3Hb mice.
Topics: Animals; Breast; Breast Neoplasms; Female; Humans; Incidence; Mammary Neoplasms, Animal; Mammary Neo | 1963 |
The role of ovarian hormones in initiating the induction of mammary cancer in rats by polynuclear hydrocarbons.
Topics: Animals; Benz(a)Anthracenes; Breast Neoplasms; Castration; Female; Humans; Hydrocarbons; Mammary Neo | 1962 |
[HISTOLOGICAL PICTURE AND HORMONE DEPENDENCE OF MAMMARY CANCER INDUCED BY 20-METHYLCHOLANTHRENE].
Topics: Animals; Breast Neoplasms; Carcinoma; Carcinoma, Ductal; Estrogens; Humans; Mammary Neoplasms, Anima | 1963 |
THE MECHANISM OF CARCINOGENESIS IN BREAST TUMOUR DEVELOPMENT IN MICE.
Topics: Animals; Breast Neoplasms; Carcinogenesis; Humans; Mammary Neoplasms, Animal; Mammary Neoplasms, Exp | 1963 |
THE EFFECTS OF TRIAMCINOLONE DIACETATE ON LEVELS OF 3-METHYLCHOLANTHRENE IN RAT MAMMARY GLANDS.
Topics: Animals; Breast Neoplasms; Histocytochemistry; Humans; Mammary Glands, Human; Mammary Neoplasms, Ani | 1963 |
THE INFLUENCE OF PSEUDOPREGNANCY ON BREAST TUMOUR INDUCTION BY METHYLCHOLANTHRENE IN IF OR F1 HYBRID (C57B1 TIMES IF) MICE.
Topics: Animals; Breast Neoplasms; Female; Humans; Limbic System; Mammary Neoplasms, Animal; Mammary Neoplas | 1963 |
INFLUENCE OF ESTRADIOL-17-BETA, PROGESTERONE AND HYDROCORTISONE ON 3-METHYLCHOLANTHRENE-INDUCED MAMMARY CANCER IN INTACT AND OVARIECTOMIZED SPRAGUE-DAWLEY RATS.
Topics: Adenocarcinoma; Adrenalectomy; Animals; Breast Neoplasms; Castration; Estradiol; Humans; Hydrocortis | 1963 |
GROWTH INHIBITION OF SARCOMA AND CARCINOMA CELLS OF HOMOZYGOUS ORIGIN.
Topics: Animals; Breast Neoplasms; Carcinoma; Fibrosarcoma; Humans; Mammary Neoplasms, Animal; Mammary Neopl | 1964 |
CHEMICAL INDUCTION OF MAMMARY CANCER IN GERM-FREE RATS.
Topics: Animals; Benz(a)Anthracenes; Breast Neoplasms; Carcinogens; Germ-Free Life; Humans; Mammary Neoplasm | 1963 |
PROLACTIN-RELEASING ACTIVITY OF 3-METHYLCHOLANTHRENE.
Topics: Animals; Breast Neoplasms; Estradiol; Humans; Mammary Neoplasms, Animal; Mammary Neoplasms, Experime | 1964 |
[COMPARATIVE STUDIES ON THE INDUCTION OF MAMMARY CARCINOMAS IN WISTAR AND SPRAGUE-DAWLEY RATS BY PERORAL ADMINISTRATION OF METHYLCHOLANTHRENE].
Topics: Animals; Breast Neoplasms; Carcinogens; Humans; Mammary Neoplasms, Animal; Mammary Neoplasms, Experi | 1964 |
PRODUCTION OF MAMMARY TUMOURS WITH 3-METHYLCHOLANTHRENE.
Topics: Adenofibroma; Adenoma; Animals; Breast Neoplasms; Humans; Mammary Neoplasms, Animal; Mammary Neoplas | 1964 |
HISTOGENESIS OF BREAST CANCER.
Topics: Animals; Breast Neoplasms; Histological Techniques; Histology; Humans; Mammary Neoplasms, Animal; Ma | 1964 |
INHIBITION OF MAMMARY CANCER IN RATS BY A DITHIOCARBAMOYLHYDRAZINE (ICI-33,828).
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Castration; Female; Humans; Hydrazines; Male; Mamm | 1964 |
EFFECT OF CASEIN, LACTALBUMIN, AND OVALBUMIN ON 3-METHYLCHOLANTHRENE-INDUCED MAMMARY CARCINOMA IN RATS.
Topics: Albumins; Animals; Body Weight; Breast Neoplasms; Caseins; Dietary Proteins; Humans; Lactalbumin; Ma | 1964 |
MURINE MAMMARY CARCINOMAS INDUCED BY INTRAVAGINAL APPLICATIONS OF METHYLCHOLANTHRENE IN MINIMAL DOSAGES.
Topics: Adenocarcinoma; Animals; Breast; Breast Neoplasms; Carcinogens; Humans; Mammary Neoplasms, Animal; M | 1964 |
THE EFFECTS OF PARTIAL HEPATECTOMY ON MAMMARY CARCINOGENESIS IN THE RAT.
Topics: Animals; Breast Neoplasms; Carcinogens; Cell Transformation, Neoplastic; Hepatectomy; Humans; Liver | 1964 |
LACK OF EFFECT OF NORETHYNODREL (ENOVID) ON METHYLCHOLANTHRENE-INDUCED MAMMARY CARCINOGENESIS IN FEMALE RATS.
Topics: Animals; Breast Neoplasms; Carcinogenesis; Estradiol; Female; Humans; Mammary Neoplasms, Animal; Mam | 1964 |
THE INFLUENCE OF PSEUDOPREGNANCY, PREGNANCY AND LACTATION ON THE INDUCTION OF BREAST TUMOURS IN AGENT-FREE MICE BY METHYLCHOLANTHRENE (MC).
Topics: Animals; Breast Feeding; Breast Neoplasms; Female; Genetics; Humans; Lactation; Mammary Neoplasms, A | 1964 |
VULNERABILITY OF THE SUBTERMINAL CHROMOSOMES OF CULTURED RAT MAMMARY CANCER CELLS TO ALTERATIONS.
Topics: Animals; Benz(a)Anthracenes; Breast Neoplasms; Chromosome Aberrations; Chromosomes; Humans; Karyomet | 1964 |
THE UTILITY OF A CARCINOGEN-INDUCED RAT MAMMARY CANCER AS A CHEMOTHERAPEUTIC SCREENING DEVICE.
Topics: Animals; Breast Neoplasms; Carcinogens; Cyclophosphamide; Dactinomycin; Diet; Diet Therapy; Humans; | 1965 |
THE CHEMICAL INDUCTION OF BREAST TUMOURS IN C57BL, IF AND F1, HYBRID (C57BL X IF) BREAST TISSUE TRANSPLANTED INTO BREAST-FREE F1 HYBRID (C57BL X IF) HOSTS.
Topics: Adenocarcinoma; Animals; Breast Neoplasms; Carcinogens; Genetics; Humans; Mammary Glands, Animal; Ma | 1965 |
NEOPLASMS IN THYMECTOMIZED MICE FOLLOWING ROOM INFECTION WITH POLYOMA VIRUS.
Topics: Animals; Breast Neoplasms; Fibrosarcoma; Humans; Mammary Neoplasms, Animal; Mammary Neoplasms, Exper | 1965 |
[HISTOLOGICAL STUDIES ON THE DEVELOPMENT OF MAMMARY TUMOUR IN MICE INDUCED BY METHYLCHOLANTHRENE IN COMBINATION WITH EITHER FORCE-BREEDING OR PITUITARY GRAFTING].
Topics: Animals; Breast Neoplasms; Breeding; Humans; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimen | 1965 |
The effect of methylcholanthrene on the incidence of mammary carcinoma in two inbred strains of mice and their reciprocal hybrids.
Topics: Animals; Breast Neoplasms; Humans; Incidence; Methylcholanthrene; Mice; Mice, Inbred Strains; Neopla | 1954 |
The evolution of mammary cancer induced in virgin female IF mice with minimal doses of locally-acting methylcholanthrene.
Topics: Animals; Biological Evolution; Breast Neoplasms; Cell Transformation, Neoplastic; Female; Humans; Me | 1954 |
The effects of oestrogens and progesterone on the chemical induction of mammary cancer in mice of the IF strain.
Topics: Animals; Breast Neoplasms; Estrogens; Humans; Methylcholanthrene; Mice; Neoplasms, Experimental; Pro | 1954 |
Breast tumor formation as a response to graded doses of methylcholanthrene and the effect of this drug on the pituitary glands of rats.
Topics: Animals; Breast Neoplasms; Humans; Methylcholanthrene; Neoplasms, Experimental; Pituitary Gland; Rat | 1959 |
Survival of skin homografts in methylcholanthrene-treated mice and in mice with spontaneous mammary cancers.
Topics: Allografts; Animals; Breast Neoplasms; Humans; Mammary Neoplasms, Experimental; Methylcholanthrene; | 1962 |
Chemical induction of breast tumours in mice of the C57B1 strain. The influence of pseudopregnancy, pregnancy and lactation on induction by methylcholanthrene.
Topics: Animals; Breast Feeding; Breast Neoplasms; Female; Humans; Lactation; Mammary Neoplasms, Experimenta | 1961 |
[Oncogenic action of methylcholanthrene per os associated with pituitary graft in XVII/G mice].
Topics: Animals; Breast Neoplasms; Estradiol; Humans; Mammary Neoplasms, Experimental; Methylcholanthrene; M | 1962 |
Inhibition of mammary cancer induction in rats with corticosteroids.
Topics: Adrenal Cortex Hormones; Animals; Breast Neoplasms; Methylcholanthrene; Rats; Triamcinolone | 1962 |
Methylcholanthrene-induced mammary tumours in a low-breast-cancer strain of mice.
Topics: Animals; Breast; Breast Neoplasms; Humans; Mammary Neoplasms, Animal; Methylcholanthrene; Mice; Neop | 1951 |
Induction of breast cancer by oestrogens and methylcholanthrene in high- and low-breast-cancer strain mice.
Topics: Animals; Breast; Breast Neoplasms; Estrogens; Humans; Methylcholanthrene; Mice; Neoplasms | 1949 |
Response of mammary-tumor-agent-free strain DBA female mice to percutaneous application of methylcholanthrene.
Topics: Animals; Breast Neoplasms; Female; Humans; Methylcholanthrene; Mice; Mice, Inbred DBA; Neoplasms | 1950 |
Assay of methylcholanthrene-induced mammary tumors of mice for the mammary tumor milk agent.
Topics: Animals; Breast; Breast Neoplasms; Humans; Mammary Neoplasms, Animal; Mammary Tumor Virus, Mouse; Me | 1950 |
Aryl hydrocarbon receptor-independent activation of estrogen receptor-dependent transcription by 3-methylcholanthrene.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Dose-Response Relationship, Drug; Endometrial Neoplasms | 2006 |
3-Methylcholanthrene and other aryl hydrocarbon receptor agonists directly activate estrogen receptor alpha.
Topics: Animals; Binding, Competitive; Breast Neoplasms; Cell Line, Tumor; Chromatin Immunoprecipitation; Cy | 2006 |
Aryl hydrocarbon receptor agonists directly activate estrogen receptor alpha in MCF-7 breast cancer cells.
Topics: Benzo(a)pyrene; Benzofurans; Binding Sites; Breast Neoplasms; Cell Line, Tumor; Cytochrome P-450 CYP | 2006 |
Potential endogenous epoxides of steroid hormones: initiators of breast and other malignancies?
Topics: Breast Neoplasms; Carcinogens; DNA; Epoxy Compounds; Estradiol; Estrogens; Hormone Replacement Thera | 2007 |
Induction of mammary cancer with methylcholanthrene; histological similarity between carcinogen-induced tumors and certain mammary neoplasms occurring spontaneously.
Topics: Animals; Breast Neoplasms; Carcinogens; Humans; Mammary Neoplasms, Animal; Methylcholanthrene; Neopl | 1949 |
In vivo studies of radioactive phosphorus in malignant tumours.
Topics: Adult; Aged; Animals; Autoradiography; Breast Neoplasms; Bronchial Neoplasms; Densitometry; Female; | 1967 |
Detection of aryl hydrocarbon hydroxylase activity in normal and neoplastic human breast epithelium.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aryl Hydrocarbon Hydroxylases; Benz(a)Anthracenes; Benzopyrenes; B | 1980 |
Identification of the class-3 aldehyde dehydrogenases present in human MCF-7/0 breast adenocarcinoma cells and normal human breast tissue.
Topics: Adenocarcinoma; Aldehyde Dehydrogenase; Benzopyrenes; Breast; Breast Neoplasms; Cell Line; Gastric M | 1994 |
Identification of a methylcholanthrene-induced aldehyde dehydrogenase in a human breast adenocarcinoma cell line exhibiting oxazaphosphorine-specific acquired resistance.
Topics: Adenocarcinoma; Aldehyde Dehydrogenase; Antineoplastic Agents; Breast Neoplasms; Cell Line; Cell Sur | 1994 |
Overexpression or polycyclic aromatic hydrocarbon-mediated induction of an apparently novel class 3 aldehyde dehydrogenase in human breast adenocarcinoma cells and its relationship to oxazaphosphorine-specific acquired resistance.
Topics: Adenocarcinoma; Aldehyde Dehydrogenase; Breast Neoplasms; Drug Resistance; Enzyme Induction; Female; | 1993 |
Multienzyme-mediated stable and transient multidrug resistance and collateral sensitivity induced by xenobiotics.
Topics: Adenocarcinoma; Aldehyde Dehydrogenase; Antineoplastic Agents; Breast Neoplasms; Carcinogens; Catech | 1997 |
BCG therapy of pleural and peritoneal growth of transplanted rat tumours.
Topics: Animals; Azo Compounds; BCG Vaccine; Benzene; Breast Neoplasms; Carcinoma, Hepatocellular; Female; F | 1975 |
Polynuclear aromatic hydrocarbon carcinogens as antiestrogens in MCF-7 human breast cancer cells: role of the Ah receptor.
Topics: Breast Neoplasms; Carcinogens; Cell Division; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme Syste | 1992 |
Breast cancer prevention by supplemental vitamin E.
Topics: Breast Neoplasms; Disease Models, Animal; Female; Fibrocystic Breast Disease; Food, Fortified; Human | 1985 |
[On the demonstration of cytophilic antibodies to cell wall preparations of beta-hemolyzed group A streptococci in tumor rats after sensitization with these organisms].
Topics: Animals; Antibodies; Ascitic Fluid; Benz(a)Anthracenes; Breast Neoplasms; Cell Wall; Erythrocytes; M | 1969 |
Some biochemical characteristics of rodent and human mammary carcinomas.
Topics: Adenocarcinoma; Animals; Benz(a)Anthracenes; Breast; Breast Neoplasms; Carcinoma, Intraductal, Nonin | 1970 |