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3-methylcholanthrene and Brain Neoplasms

3-methylcholanthrene has been researched along with Brain Neoplasms in 55 studies

Methylcholanthrene: A carcinogen that is often used in experimental cancer studies.
3-methylcholanthrene : A pentacyclic ortho- and peri-fused polycyclic arene consisting of a dihydrocyclopenta[ij]tetraphene ring system with a methyl substituent at the 3-position.

Brain Neoplasms: Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.

Research Excerpts

ExcerptRelevanceReference
" Transplacental tumor induction in rats by ethylnitrosourea produced oligodendrogliomas and mixed gliomas in the cerebrum and spinal cord, and malignant Schwannomas of the trigeminal nerve."3.66The immunocytochemical localization of GFA protein in experimental murine CNS tumors. ( Conley, FK, 1979)
"The models discussed include brain tumors produced by local implants of carcinogenic hydrocarbons and by the administration of resorptive N-nitroso compounds, some of the cell lines derived from the latter, tumors resulting from the intracerebral inoculation of oncogenic viruses, and the differentiating neuroepithelial component of a transplantable mouse teratoma."2.36Correlation of animal brain tumor models with human neuro-oncology. ( Rubinstein, LJ, 1977)

Research

Studies (55)

TimeframeStudies, this research(%)All Research%
pre-199051 (92.73)18.7374
1990's3 (5.45)18.2507
2000's1 (1.82)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
MULLIGAN, RM2
NEUBUERGER, KT2
PINTO, F1
AKSEL, IS1
AYKAN, TB1
KIRSCH, WM1
KAWAI, S1
WRIGHT, RL2
SATO, K1
MAKI, Y1
HORIE, T1
IABLONOVSKAIA, LIa1
AVTSYN, AP1
PERESE, DM1
WECHSLER, W1
ZIMMERMAN, HM3
KRIGMAN, MR1
MANUELIDIS, EE2
Kiya, K1
Kitaoka, T1
Okamoto, H1
Harada, K1
Uozumi, T1
Toge, T1
Hattori, T1
Machida, H1
Muller, PJ1
Shin, KH1
Shin, DH1
von Metzler, A2
Nitsch, C2
Inoue, M1
Plautz, GE1
Shu, S1
Ecsedy, JA1
Manfredi, MG2
Yohe, HC1
Seyfried, TN2
Ranes, MK1
El-Abbadi, M1
Mukherjee, P1
Platt, FM1
Konikowski, T2
JPAHNS, MF1
Haynie, P1
Glenn, HJ2
Manuelidis, L1
Rubinstein, LJ1
Nakao, S1
Nakagawa, H1
Hori, M1
Hasegawa, H1
Mogami, H2
Hayakawa, T2
Nakata, Y1
Levitt, RC1
Fysh, JM1
Jensen, NM1
Nebert, DW1
Conley, FK1
Gershbein, LL1
Benuck, I1
Osborn, DE1
Sadler, TE1
Castro, JE1
Stahn, R1
Rose, S1
Sanborn, S1
West, G1
Herschman, H1
Gallinger, S1
Hoskin, DW1
Mullen, JB1
Wong, AH1
Roder, JC1
Kroh, H7
Iglesias, JR1
Matyja, E1
Aruffo, C1
Meier-Hauf, K1
Cervos-Navarro, J1
Djurhuus, R1
Laerum, OD1
Lillehaug, JR1
Renkawek, K2
Ushio, Y1
Horibata, K1
Hopewell, JW1
Wright, EA1
Handa, H1
Handa, J1
Koyama, M1
Majdecki, T1
Shapiro, WR1
Posner, JB1
Mandybur, TI1
Rubin, R1
Ames, RP1
Sutton, CH1
SzumaƄska, G1
Haynie, TP1
Kobayashi, T1
Bakay, L1
Spencer, AT1
Smith, WT1
Sil, R1
Fukui, M1
Wahal, KM1
Ansari, IH1
Ikuta, F1
Karahashi, Y1
Sheptak, P1
Moossy, J1
Goldring, S1

Reviews

2 reviews available for 3-methylcholanthrene and Brain Neoplasms

ArticleYear
Correlation of animal brain tumor models with human neuro-oncology.
    National Cancer Institute monograph, 1977, Volume: 46

    Topics: Animals; Brain Neoplasms; Cell Differentiation; Cell Line; Disease Models, Animal; Glioma; Humans; M

1977
[Brain tumors].
    Nihon rinsho. Japanese journal of clinical medicine, 1972, Volume: 30, Issue:1

    Topics: Animals; Astrocytoma; Benz(a)Anthracenes; Brain Neoplasms; Diethylstilbestrol; Ependymoma; Female; G

1972

Other Studies

53 other studies available for 3-methylcholanthrene and Brain Neoplasms

ArticleYear
Intracranial neoplasms produced in dogs by methylcholanthrene.
    Experimental medicine and surgery, 1946, Volume: 4

    Topics: Animals; Brain; Brain Neoplasms; Dogs; Methylcholanthrene; Neoplasms; Neoplasms, Experimental

1946
Intracranial neoplasms produced in dogs by methylcholanthrene.
    The American journal of pathology, 1946, Volume: 22

    Topics: Animals; Brain; Brain Neoplasms; Dogs; Methylcholanthrene; Neoplasms; Neoplasms, Experimental

1946
Encephalic tumors obtained after the implantation of cylinders of methylcholanthrene in the parietal cortex of the rat; contribution to the study of experimental carcinogenesis; communication on the results obtained in 10 animals.
    Acta - Unio Internationalis Contra Cancrum, 1955, Volume: 11, Issue:6

    Topics: Animals; Brain Neoplasms; Carcinogenesis; Methylcholanthrene; Neoplasms; Neoplasms, Experimental; Pa

1955
Growth behavior of the rabies virus in a glioblastomatous tumor induced with methylcholanthrene in mice.
    World neurology, 1961, Volume: 2

    Topics: Animals; Brain; Brain Neoplasms; Glioma; Methylcholanthrene; Mice; Rabies; Rabies Vaccines; Rabies v

1961
Histochemical and quantitative analysis of alkaline phosphatase during the course of experimental intracranial neoplasia.
    Neurology, 1963, Volume: 13

    Topics: Alkaline Phosphatase; Animals; Brain Neoplasms; Cholesterol; Methylcholanthrene; Neoplasms; Neoplasm

1963
[EXPERIMENTAL STUDIES ON BRAIN TUMORS].
    Kita Kanto igaku. Kitakanto medical journal, 1963, Volume: 13

    Topics: Animals; Brain Neoplasms; Glioma; Methylcholanthrene; Mice; Neoplasms; Neoplasms, Experimental; Path

1963
NEOVASCULARIZATION IN EXPERIMENTAL GLIOMAS.
    Journal of neuropathology and experimental neurology, 1963, Volume: 22

    Topics: Animals; Brain Neoplasms; Cerebral Angiography; Cerebrovascular Circulation; Ependymoma; Glioma; Met

1963
[EXPERIMENTAL STUDIES ON BRAIN TUMORS, WITH SPECIAL REFERENCE TO GLIOMAS AND THEIR TRANSPLANTS IN THE MOUSE].
    Kita Kanto igaku. Kitakanto medical journal, 1963, Volume: 13

    Topics: Animals; Brain Neoplasms; Cerebellar Neoplasms; Electrons; Glioma; Methylcholanthrene; Mice; Microsc

1963
[ON THE INTRACRANIAL EPIDERMOID].
    No to shinkei = Brain and nerve, 1964, Volume: 16

    Topics: Benz(a)Anthracenes; Brain Neoplasms; Carcinoma, Squamous Cell; Cerebellar Neoplasms; Cerebellopontin

1964
[MALIGNANT GLIOMA IN RABBITS INDUCED BY METHYLCHOLANTHRENE].
    Arkhiv patologii, 1963, Volume: 25

    Topics: Animals; Astrocytoma; Brain Neoplasms; Embolism; Embolism, Air; Ependymoma; Glioma; Hemangioma; Meth

1963
AGE AND SEX FACTORS IN EXPERIMENTAL BRAIN TUMORS.
    Surgical forum, 1964, Volume: 15

    Topics: Aging; Animals; Brain Abscess; Brain Neoplasms; Carcinoma, Squamous Cell; Glioblastoma; Glioma; Meth

1964
[ELECTRON MICROSCOPIC STUDY OF AN EXPERIMENTALLY INDUCED INTRACRANIAL SARCOMA IN ALBINO MICE].
    Acta neuropathologica, 1963, Nov-05, Volume: 3

    Topics: Animals; Brain Neoplasms; Carcinogens; Electrons; Fibrosarcoma; Methylcholanthrene; Mice; Microscopy

1963
SOME CONTRIBUTIONS OF ELECTRON MICROSCOPY TO PROBLEMS IN PATHOLOGY.
    Bulletin of the New York Academy of Medicine, 1964, Volume: 40

    Topics: Animals; Benz(a)Anthracenes; Benzopyrenes; Brain Diseases; Brain Injuries; Brain Neoplasms; Carcinog

1964
MORPHOLOGICAL AND PERMEABILITY CHANGES IN THE CEREBRAL PARENCHYMA ADJACENT TO HETEROLOGOUS INTRACEREBRAL TUMORS.
    Journal of neuropathology and experimental neurology, 1965, Volume: 24

    Topics: Animals; Blood-Brain Barrier; Brain Edema; Brain Neoplasms; Capillary Permeability; Cattle; Cerebrov

1965
Vascular permeability in experimental brain tumors.
    Angiology, 1967, Volume: 18, Issue:2

    Topics: Animals; Blood-Brain Barrier; Brain Neoplasms; Capillary Permeability; Carbon; Ependymoma; Methylcho

1967
[Antitumor effect of Corynebacterium parvum and poly ICLC on experimental brain tumors].
    Neurologia medico-chirurgica, 1983, Volume: 23, Issue:11

    Topics: Adjuvants, Immunologic; Animals; Brain Neoplasms; Carboxymethylcellulose Sodium; Glioma; Interferon

1983
The murine ependymoblastoma: growth pattern and survival in C57Bl/6J mice.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1983, Volume: 10, Issue:2

    Topics: Animals; Brain Neoplasms; Ependymoma; Methylcholanthrene; Mice; Mice, Inbred C57BL; Neoplasms, Exper

1983
[Effects of 3-methylcholanthrene and 3-methylcholanthrene plus piracetam on the gamma-amino-butyric acid (GABA) content of several cerebral regions (author's transl)].
    Journal of cancer research and clinical oncology, 1981, Volume: 101, Issue:3

    Topics: Aminooxyacetic Acid; Animals; Brain Chemistry; Brain Neoplasms; gamma-Aminobutyric Acid; Methylchola

1981
Treatment of intracranial tumors by systemic transfer of superantigen-activated tumor-draining lymph node T cells.
    Cancer research, 1996, Oct-15, Volume: 56, Issue:20

    Topics: Animals; Brain Neoplasms; Carcinogens; CD4-CD8 Ratio; Cross Reactions; Female; Fibrosarcoma; Immunot

1996
Ganglioside biosynthetic gene expression in experimental mouse brain tumors.
    Cancer research, 1997, Apr-15, Volume: 57, Issue:8

    Topics: Animals; Brain Neoplasms; Carcinogens; Ependymoma; Gangliosides; Gene Expression Regulation, Enzymol

1997
N -butyldeoxynojirimycin reduces growth and ganglioside content of experimental mouse brain tumours.
    British journal of cancer, 2001, Apr-20, Volume: 84, Issue:8

    Topics: 1-Deoxynojirimycin; Animals; Body Weight; Brain; Brain Neoplasms; Cell Count; Cell Division; Ganglio

2001
Brain tumor-scanning agents compared in an animal model.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1975, Volume: 16, Issue:3

    Topics: Animals; Ascorbic Acid; Bleomycin; Brain Neoplasms; Chlormerodrin; Gallium; Indium; Iron; Mercury Is

1975
Amount of satellite DNA in four experimentally induced tumors of the central nervous system. Quantitative changes in a glioblastoma producing C-type particles.
    Journal of the National Cancer Institute, 1976, Volume: 56, Issue:1

    Topics: Brain Chemistry; Brain Neoplasms; Cell Line; Cell Nucleus; DNA; DNA, Satellite; Glioma; Methylcholan

1976
[Partial characterization of surface tumor associated antigens of established murine glioma cell line (203-glioma) (author's transl)].
    No to shinkei = Brain and nerve, 1979, Volume: 31, Issue:1

    Topics: Animals; Antigens, Neoplasm; Brain Neoplasms; Cell Line; Cell Membrane; Glioma; Methylcholanthrene;

1979
[The anti-tumor effect of ACNU and X-irradiation on mouse glioma (author's transl)].
    No to shinkei = Brain and nerve, 1979, Volume: 31, Issue:9

    Topics: Animals; Brain Neoplasms; Cell Division; DNA, Neoplasm; Glioma; Male; Methylcholanthrene; Mice; Neop

1979
The Ah locus: biochemical basis for genetic differences in brain tumor formation in mice.
    Genetics, 1979, Volume: 92, Issue:4

    Topics: Alleles; Animals; Aryl Hydrocarbon Hydroxylases; Brain Neoplasms; Chromosome Mapping; Cytochrome P-4

1979
The immunocytochemical localization of GFA protein in experimental murine CNS tumors.
    Acta neuropathologica, 1979, Jan-12, Volume: 45, Issue:1

    Topics: Animals; Astrocytes; Brain Neoplasms; Cranial Nerve Neoplasms; Ependymoma; Ethylnitrosourea; Glioma;

1979
Cortical implantation of hydrocarbons in rats and mice.
    Oncology, 1975, Volume: 31, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Brain Diseases; Brain Neoplasms; Carc

1975
Effects of C. parvum on growth and induction of intracerebral tumours in mice.
    British journal of cancer, 1977, Volume: 35, Issue:4

    Topics: Animals; Brain Neoplasms; Immunization; Immunotherapy; Methylcholanthrene; Mice; Mice, Inbred BALB C

1977
Effects of nerve growth factor administration of N-ethyl-N-nitrosourea carcinogenesis.
    Brain research, 1975, Oct-17, Volume: 96, Issue:2

    Topics: Animals; Brain Neoplasms; Cells, Cultured; Drug Interactions; Ethylnitrosourea; Female; Male; Methyl

1975
Comparison of cellular immunotherapies and anti-CD3 in the treatment of MCA-38-LD experimental hepatic metastases in C57BL/6 mice.
    Cancer research, 1990, Apr-15, Volume: 50, Issue:8

    Topics: Adenocarcinoma; Animals; Antigens, Differentiation, T-Lymphocyte; Brain Neoplasms; CD3 Complex; Cell

1990
Monoamine content in rat brain during carcinogenesis and the influence of the CNS drugs piracetam and imipramine.
    Die Naturwissenschaften, 1985, Volume: 72, Issue:10

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Brain Neoplasms; Caudate Nucleus; Female;

1985
Glial elements in experimental cerebral sarcomas.
    Neuropatologia polska, 1989, Volume: 27, Issue:4

    Topics: Animals; Brain Neoplasms; Fibrosarcoma; Giant Cell Tumors; Glial Fibrillary Acidic Protein; Immunohi

1989
Computer classification of experimental brain tumors in mice.
    Experimental pathology, 1988, Volume: 35, Issue:1

    Topics: Animals; Bayes Theorem; Brain; Brain Neoplasms; Decision Making, Computer-Assisted; Male; Methylchol

1988
Ornithine decarboxylase activity in foetal rat brain cells and in the mouse embryo fibroblasts C3H/10T1/2 CL8 cells: differences in response to medium change and to the tumor promoter TPA.
    The International journal of biochemistry, 1987, Volume: 19, Issue:6

    Topics: Animals; Brain; Brain Neoplasms; Cell Line; Cell Transformation, Neoplastic; Culture Media; Embryo,

1987
The morphological and histoenzymatic properties of experimental brain sarcomas cultured in vitro.
    Zeitschrift fur Krebsforschung, 1971, Volume: 75, Issue:2

    Topics: Acid Phosphatase; Animals; Brain Neoplasms; Culture Techniques; Fibrosarcoma; Glucosephosphate Dehyd

1971
The uptake, distribution and anti-tumor activity of bleomycin in gliomas in the mouse.
    European journal of cancer, 1974, Volume: 10, Issue:3

    Topics: Animals; Biological Assay; Bleomycin; Brain Neoplasms; Carbon Radioisotopes; Glioma; Injections, Int

1974
The importance of implantation site in cerebral carcinogenesis in rats.
    Cancer research, 1969, Volume: 29, Issue:11

    Topics: Animals; Astrocytoma; Benzopyrenes; Brain Neoplasms; Cerebral Ventricles; Ependymoma; Female; Gliobl

1969
Experimental cerebral glio-sarcomas in mice.
    Polish medical journal, 1971, Volume: 10, Issue:1

    Topics: Animals; Brain Neoplasms; Ependymoma; Fibrosarcoma; Glioblastoma; Glioma; Methylcholanthrene; Mice;

1971
A study of the ultrastructure of experimentally induced brain sarcomas.
    Archiv fur Geschwulstforschung, 1973, Volume: 41, Issue:4

    Topics: Animals; Brain Neoplasms; Cell Membrane; Cell Nucleus; Collagen; Connective Tissue; Culture Techniqu

1973
Corticosteroid hormones. Effects in an experimental brain tumor.
    Archives of neurology, 1974, Volume: 30, Issue:3

    Topics: Animals; Brain; Brain Edema; Brain Neoplasms; Dexamethasone; DNA, Neoplasm; Ependymoma; Male; Methyl

1974
Effect of beta-irradiation on 3-methylcholanthrene induction of brain tumors in mice.
    Journal of the National Cancer Institute, 1974, Volume: 53, Issue:2

    Topics: Animals; Brain; Brain Neoplasms; Dose-Response Relationship, Radiation; Male; Methylcholanthrene; Mi

1974
Virus-like particles in murine ependymoblastoma.
    Journal of neuropathology and experimental neurology, 1969, Volume: 28, Issue:3

    Topics: Animals; Brain Neoplasms; Ependymoma; Inclusion Bodies, Viral; Methylcholanthrene; Mice; Microscopy,

1969
The activity of certain respiratory enzymes in experimental brain tumors in mice.
    Polish medical journal, 1972, Volume: 11, Issue:3

    Topics: Animals; Astrocytoma; Brain Neoplasms; Ependymoma; Fibrosarcoma; Glioma; Glucosephosphate Dehydrogen

1972
Renal clearance and brain tumor localization in mice of 99 m Tc compounds of (Sn), DTPA, (iron-ascorbic acid) DTPA, and iron-ascorbic acid.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1972, Volume: 13, Issue:11

    Topics: Animals; Ascorbic Acid; Brain Chemistry; Brain Neoplasms; Iron; Kidney; Liver; Methylcholanthrene; M

1972
The extracellular space in experimental brain tumors.
    Acta neurologica Scandinavica, 1971, Volume: 47, Issue:3

    Topics: Animals; Autoradiography; Brain Neoplasms; Carbon Isotopes; Extracellular Space; Glioma; Inulin; Men

1971
Behaviour of intracerebral autografts of mouse tail skin pre-treated with a single application of 20-methylcholanthrene.
    Nature, 1965, Aug-07, Volume: 207, Issue:997

    Topics: Animals; Brain Edema; Brain Neoplasms; Carcinoma, Squamous Cell; Dermoid Cyst; Glioma; Methylcholant

1965
Production of experimental brain tumours by 20-methylcholanthrene in Swiss mice.
    Neurology India, 1969, Volume: 17, Issue:4

    Topics: Anesthesia; Animals; Astrocytoma; Body Weight; Brain Neoplasms; Female; Glioma; Male; Methylcholanth

1969
Morphological and histoenzymatic features of mouse brain gliomas induced by methylcholantrene.
    Folia histochemica et cytochemica, 1970, Volume: 8, Issue:3

    Topics: Acid Phosphatase; Alkaline Phosphatase; Aminopeptidases; Animals; Astrocytoma; Brain Neoplasms; Epen

1970
[Experimental brain tumor].
    Igaku kenkyu. Acta medica, 1970, Volume: 40, Issue:2

    Topics: Animals; Brain Neoplasms; Female; Glioma; Male; Methylcholanthrene; Mice; Neoplasm Transplantation;

1970
Experimental brain tumours in albino mice.
    The Indian journal of medical research, 1968, Volume: 56, Issue:6

    Topics: Animals; Brain Neoplasms; Fibrosarcoma; Glioma; Meningioma; Methylcholanthrene; Mice

1968
The viral particles in the reactive cells of the brain induced by chemical carcinogens.
    International journal of neurology, 1965, Volume: 5, Issue:1

    Topics: Animals; Benzopyrenes; Brain Neoplasms; Female; Male; Methylcholanthrene; Mice; Neoplasms, Experimen

1965
Intracellular potentials from experimental glial tumors.
    Archives of neurology, 1966, Volume: 15, Issue:5

    Topics: Animals; Brain Neoplasms; Cell Membrane; Cerebral Cortex; Electrophysiology; Glioma; Methylcholanthr

1966