3-methylcholanthrene has been researched along with Anorexia in 13 studies
Methylcholanthrene: A carcinogen that is often used in experimental cancer studies.
3-methylcholanthrene : A pentacyclic ortho- and peri-fused polycyclic arene consisting of a dihydrocyclopenta[ij]tetraphene ring system with a methyl substituent at the 3-position.
Anorexia: The lack or loss of APPETITE accompanied by an aversion to food and the inability to eat. It is the defining characteristic of the disorder ANOREXIA NERVOSA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Anorexia-cachexia is a common and severe cancer-related complication but the underlying mechanisms are largely unknown." | 1.39 | Proteomic profiling of the hypothalamus in a mouse model of cancer-induced anorexia-cachexia. ( Blomqvist, A; Ihnatko, R; Post, C, 2013) |
| "On day 16, anorexia has appeared only in CTR and STD-AOX animals." | 1.39 | Timing of antioxidant supplementation is critical in improving anorexia in an experimental model of cancer. ( Citro, G; De Luca, S; Fazi, L; Laviano, A; Mari, A; Molfino, A; Muscaritoli, M; Ramaccini, C; Rossi Fanelli, F, 2013) |
| "While the pathophysiology of cancer anorexia-cachexia is poorly understood, evidence indicates that pro-inflammatory cytokines are key mediators of this response." | 1.36 | Deletion of the gene encoding MyD88 protects from anorexia in a mouse tumor model. ( Bäckhed, F; Blomqvist, A; Engblom, D; Ruud, J, 2010) |
| "Since cancer anorexia mainly results from an initial reduction of meal number and the inhibition of VMN led to an increase in meal number, the early effect of tumor growth on VMN activity may be an early step leading to reduced food intake." | 1.31 | VMN/LHA functional inhibition in tumor-bearing rats suggests hypothalamic involvement in cancer anorexia. ( Gleason, JR; Laviano, A; Meguid, MM; Rossi-Fanelli, F, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (30.77) | 18.7374 |
| 1990's | 3 (23.08) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 4 (30.77) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ihnatko, R | 1 |
| Post, C | 1 |
| Blomqvist, A | 3 |
| Ruud, J | 2 |
| Bäckhed, F | 2 |
| Engblom, D | 2 |
| Molfino, A | 1 |
| De Luca, S | 1 |
| Muscaritoli, M | 1 |
| Citro, G | 1 |
| Fazi, L | 1 |
| Mari, A | 1 |
| Ramaccini, C | 1 |
| Rossi Fanelli, F | 1 |
| Laviano, A | 2 |
| Wilhelms, DB | 1 |
| Nilsson, A | 1 |
| Eskilsson, A | 1 |
| Tang, YJ | 1 |
| Ströhle, P | 1 |
| Caesar, R | 1 |
| Schwaninger, M | 1 |
| Wunderlich, T | 1 |
| Meguid, MM | 2 |
| Gleason, JR | 1 |
| Rossi-Fanelli, F | 1 |
| Makarenko, IG | 1 |
| Gatto, L | 1 |
| Chen, C | 1 |
| Ramos, EJ | 1 |
| Goncalves, CG | 1 |
| Ugrumov, MV | 1 |
| Karlberg, HI | 1 |
| Kern, KA | 1 |
| Fischer, JE | 6 |
| Popp, MB | 1 |
| Morrison, SD | 1 |
| Brennan, MF | 1 |
| Chance, WT | 5 |
| Balasubramaniam, A | 2 |
| Sheriff, S | 1 |
| Thompson, H | 1 |
| Mohapatra, B | 1 |
| Ramo, J | 1 |
| Zhang, FS | 1 |
| Cao, L | 1 |
| Nelson, JL | 1 |
| Foley-Nelson, T | 1 |
| van Lammeren, FM | 1 |
13 other studies available for 3-methylcholanthrene and Anorexia
| Article | Year |
|---|---|
Proteomic profiling of the hypothalamus in a mouse model of cancer-induced anorexia-cachexia.
Topics: Animals; Anorexia; Cachexia; Disease Models, Animal; Dynamin I; Gene Expression Regulation, Neoplast | 2013 |
Deletion of the gene encoding MyD88 protects from anorexia in a mouse tumor model.
Topics: Animals; Anorexia; Appetite; Body Weight; Cachexia; Disease Models, Animal; Eating; Female; Methylch | 2010 |
Timing of antioxidant supplementation is critical in improving anorexia in an experimental model of cancer.
Topics: Animals; Anorexia; Antioxidants; Ascorbic Acid; Body Weight; Diet; Dietary Supplements; Disease Mode | 2013 |
Inflammation- and tumor-induced anorexia and weight loss require MyD88 in hematopoietic/myeloid cells but not in brain endothelial or neural cells.
Topics: Animals; Anorexia; Brain; Cachexia; Chimera; Endothelial Cells; Inflammation; Methylcholanthrene; Mi | 2013 |
VMN/LHA functional inhibition in tumor-bearing rats suggests hypothalamic involvement in cancer anorexia.
Topics: Animals; Anorexia; Colchicine; Eating; Hypothalamus; Hypothalamus, Middle; Male; Methylcholanthrene; | 2002 |
Normalization of hypothalamic serotonin (5-HT 1B) receptor and NPY in cancer anorexia after tumor resection: an immunocytochemical study.
Topics: Animals; Anorexia; Body Weight; Diagnostic Imaging; Eating; Hypothalamus; Immunohistochemistry; Male | 2005 |
Albumin turnover in sarcoma-bearing rats in relation to cancer anorexia.
Topics: Albumins; Animals; Anorexia; Body Water; Body Weight; Eating; Feeding and Eating Disorders; Humans; | 1983 |
Total parenteral nutrition in a methylcholanthrene-induced rat sarcoma model.
Topics: Animals; Anorexia; Body Weight; Energy Metabolism; Methylcholanthrene; Nutrition Disorders; Parenter | 1981 |
Possible role of neuropeptide Y in experimental cancer anorexia.
Topics: Ammonia; Animals; Anorexia; Brain; Eating; Hypothalamus; Male; Methylcholanthrene; Neoplasm Transpla | 1994 |
Assessment of feeding response of tumor-bearing rats to hypothalamic injection and infusion of neuropeptide Y.
Topics: Animals; Anorexia; Appetite Stimulants; Carcinogens; Feeding Behavior; Hypothalamus; Infusion Pumps, | 1996 |
Methionine sulfoximine intensifies cancer anorexia.
Topics: Ammonia; Animals; Anorexia; Biogenic Monoamines; Brain Chemistry; Male; Methionine Sulfoximine; Meth | 1991 |
Hyperammonemia in anorectic tumor-bearing rats.
Topics: Amino Acids; Ammonia; Animals; Anorexia; Body Weight; Brain; Eating; Feeding and Eating Disorders; G | 1988 |
Feeding elicited by cholinergic and adrenergic hypothalamic stimulation of anorectic tumor-bearing rats.
Topics: Animals; Anorexia; Appetite; Feeding and Eating Disorders; Feeding Behavior; Hypothalamus; Injection | 1988 |