Page last updated: 2024-10-21

3-methylcholanthrene and Aneuploid

3-methylcholanthrene has been researched along with Aneuploid in 13 studies

Methylcholanthrene: A carcinogen that is often used in experimental cancer studies.
3-methylcholanthrene : A pentacyclic ortho- and peri-fused polycyclic arene consisting of a dihydrocyclopenta[ij]tetraphene ring system with a methyl substituent at the 3-position.

Research Excerpts

ExcerptRelevanceReference
"Rhabdomyosarcomas were induced in mice by intramuscular injections of crystalline nickel sulfide and 3-methylcholanthrene."3.67Chromosomal changes in cell lines from mouse tumors induced by nickel sulfide and methylcholanthrene. ( Biggart, NW; Christie, NT; Murphy, EC; Tummolo, DM, 1988)
"We propose a novel mechanism for aneuploidy generation that involves impaired telomere replication upon loss of cohesin-SA1, with clear implications in tumourigenesis."1.38Cohesin-SA1 deficiency drives aneuploidy and tumourigenesis in mice due to impaired replication of telomeres. ( Blasco, MA; Cañamero, M; Carretero, M; Cuadrado, A; Drosopoulos, WC; Losada, A; Martínez, P; Remeseiro, S; Schildkraut, CL, 2012)
"As a result, aneuploidy is now generally viewed as a consequence, and mutated genes as a cause of cancer."1.31Aneuploidy precedes and segregates with chemical carcinogenesis. ( Duesberg, P; Hehlmann, R; Kraemer, A; Li, R; Rasnick, D; Rausch, C; Willer, A; Yerganian, G, 2000)
"Benzo[a]pyrene (BP) induced aneuploidy at 2."1.30Aneuploidy induction by benzo[a]pyrene and polyploidy induction by 7,12-dimethylbenz[a]anthracene in Chinese hamster cell lines V79-MZ and V79. ( Glatt, HR; Hayashi, M; Matsuoka, A; Ozaki, M; Sakamoto, H; Sofuni, T; Takeshita, K, 1997)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19907 (53.85)18.7374
1990's1 (7.69)18.2507
2000's3 (23.08)29.6817
2010's2 (15.38)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mukherjee, S1
Manna, S1
Pal, D1
Mukherjee, P1
Panda, CK1
Remeseiro, S1
Cuadrado, A1
Carretero, M1
Martínez, P1
Drosopoulos, WC1
Cañamero, M1
Schildkraut, CL1
Blasco, MA1
Losada, A1
Matsuoka, A1
Ozaki, M1
Takeshita, K1
Sakamoto, H1
Glatt, HR1
Hayashi, M1
Sofuni, T1
Duesberg, P1
Li, R1
Rasnick, D1
Rausch, C1
Willer, A1
Kraemer, A1
Yerganian, G1
Hehlmann, R1
Fujikawa-Yamamoto, K1
Wang, S1
Yamagishi, H1
Miyagoshi, M1
Busund, LT1
Killie, MK1
Bartnes, K1
Olsen, R1
Seljelid, R1
Freeman, AE1
Lake, RS1
Igel, HJ1
Gernand, L1
Pezzutti, MR1
Malone, JM1
Mark, C1
Benedict, WF1
Fisher, ER1
Shoemaker, RH1
Palekar, AS1
Sennerstam, R1
Kato, H1
Auer, GU1
Christie, NT1
Tummolo, DM1
Biggart, NW1
Murphy, EC1
Popescu, NC1
Olinici, CD1
Casto, BC1
DiPaolo, JA1
Vakhtin, IuB1
Borkhsenius, TV1
Shvemberger, IN1
Manocha, SL1

Other Studies

13 other studies available for 3-methylcholanthrene and Aneuploid

ArticleYear
Sequential loss of cell cycle checkpoint control contributes to malignant transformation of murine embryonic fibroblasts induced by 20-methylcholanthrene.
    Journal of cellular physiology, 2010, Volume: 224, Issue:1

    Topics: Aneuploidy; Animals; Antimetabolites; Azacitidine; Carcinogens; Cell Cycle; Cell Cycle Proteins; Cel

2010
Cohesin-SA1 deficiency drives aneuploidy and tumourigenesis in mice due to impaired replication of telomeres.
    The EMBO journal, 2012, May-02, Volume: 31, Issue:9

    Topics: Aneuploidy; Animals; Carcinogens; Cell Cycle Proteins; Cell Line; Chromatids; Chromosomal Proteins,

2012
Aneuploidy induction by benzo[a]pyrene and polyploidy induction by 7,12-dimethylbenz[a]anthracene in Chinese hamster cell lines V79-MZ and V79.
    Mutagenesis, 1997, Volume: 12, Issue:5

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Aneuploidy; Animals; Benzo(a)pyrene; Cell Cycle; Cell Line; CHO Ce

1997
Aneuploidy precedes and segregates with chemical carcinogenesis.
    Cancer genetics and cytogenetics, 2000, Volume: 119, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Aneuploidy; Animals; Carcinogens; Cell Line, Transformed; Cell Tra

2000
Temperature dependence in proliferation of tetraploid Meth-A cells in comparison with the parent diploid cells.
    Cell structure and function, 2001, Volume: 26, Issue:5

    Topics: Aneuploidy; Animals; Cell Division; Cell Size; Diploidy; Electron Spin Resonance Spectroscopy; Flow

2001
Spontaneous hybridization of macrophages and Meth A sarcoma cells.
    International journal of cancer, 2002, Apr-01, Volume: 98, Issue:4

    Topics: Aneuploidy; Animals; Cell Division; Coculture Techniques; DNA; Female; Hybrid Cells; Macrophages, Pe

2002
Heteroploid conversion of human skin cells by methylcholanthrene.
    Proceedings of the National Academy of Sciences of the United States of America, 1977, Volume: 74, Issue:6

    Topics: Adolescent; Aneuploidy; Bromodeoxyuridine; Cells, Cultured; Child; Chromosomes; Epithelium; Female;

1977
Identification of premalignant hyperplasia in methylcholanthrene-induced mammary tumorogenesis.
    Laboratory investigation; a journal of technical methods and pathology, 1975, Volume: 33, Issue:4

    Topics: Aneuploidy; Animals; Chromosome Aberrations; Estradiol; Female; Hyperplasia; Mammary Glands, Animal;

1975
Dissociation of cellular protein and DNA content in mild and moderate dysplasia as a reflection of the degree of aneuploidy in cancer.
    Analytical and quantitative cytology and histology, 1989, Volume: 11, Issue:4

    Topics: Aneuploidy; Animals; Bronchial Neoplasms; Carcinogens; Carcinoma; Cell Transformation, Neoplastic; D

1989
Chromosomal changes in cell lines from mouse tumors induced by nickel sulfide and methylcholanthrene.
    Cell biology and toxicology, 1988, Volume: 4, Issue:4

    Topics: Aneuploidy; Animals; Blotting, Northern; Blotting, Southern; Carcinogenicity Tests; Chromosome Aberr

1988
Random chromosome changes following SA7 transformation of Syrian hamster cells.
    International journal of cancer, 1974, Oct-15, Volume: 14, Issue:4

    Topics: Adenoviridae; Aneuploidy; Animals; Animals, Newborn; Benz(a)Anthracenes; Cell Transformation, Neopla

1974
[Variation and selection in clone populations of murine rhabdomyosarcoma in vivo. I. Frequency of genomic mutations].
    Tsitologiia, 1972, Volume: 14, Issue:9

    Topics: Aneuploidy; Animals; Cell Nucleus; Chromosome Aberrations; Clone Cells; DNA, Neoplasm; Methylcholant

1972
Microspectrophotometric studies of DNA on the epithelial tumors induced by 3 methylcholanthrene and croton oil treatment in mice.
    Acta histochemica, 1969, Volume: 34, Issue:2

    Topics: Aneuploidy; Animals; Cell Transformation, Neoplastic; Croton Oil; Diploidy; DNA, Neoplasm; Epitheliu

1969