Page last updated: 2024-10-21

3-methylcholanthrene and Aging

3-methylcholanthrene has been researched along with Aging in 67 studies

Methylcholanthrene: A carcinogen that is often used in experimental cancer studies.
3-methylcholanthrene : A pentacyclic ortho- and peri-fused polycyclic arene consisting of a dihydrocyclopenta[ij]tetraphene ring system with a methyl substituent at the 3-position.

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

ExcerptRelevanceReference
"The effect of post maturational aging on the in vivo disposition of theophylline was examined in the Mongolian gerbils (Meriones unguiculatus) aged 30-39 (old), 12-18 (middle-aged) and 3 (young) months following a 20 mg/kg i."3.68The effects of age on the pharmacokinetics and biotransformation of theophylline in vivo and in vitro in the Mongolian gerbil (Meriones unguiculatus). ( Lesko, L; McMahon, TF; Peggins, JO; Weiner, M, 1992)
" A small amount of any of 5 polynuclear aromatic hydrocarbons or of an aromatic amine given before the highly toxic dose of 7,12-DMBA resulted in survival for more than 2 months and the specific atrophy of testis which follows 7,12-DMBA was largely prevented."1.24AROMATIC-INDUCED PREVENTION OF FETAL TOXICITY OF 7,12-DIMETHYLBENZ(ALPHA)ANTHRACENE. ( FORD, E; FUKUNISHI, R; HUGGINS, C; JENSEN, EV, 1964)

Research

Studies (67)

TimeframeStudies, this research(%)All Research%
pre-199050 (74.63)18.7374
1990's14 (20.90)18.2507
2000's3 (4.48)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
MONTAGNA, W1
CHASE, HB1
BROWN, PJ1
SAXEN, EA1
KANDUTSCH, AA1
MURPHY, ED1
DREISBACH, ME1
LASNITZKI, I1
HUGGINS, C1
FORD, E1
FUKUNISHI, R1
JENSEN, EV1
YASUHIRA, K1
PERESE, DM1
KUNTZMAN, R1
JACOBSON, M1
SCHNEIDMAN, K1
CONNEY, AH2
Kashiwada, S1
Goka, K1
Shiraishi, H1
Arizono, K1
Ozato, K1
Wakamatsu, Y1
Hinton, DE1
Law, FC1
So, EM1
Thomas, PE2
Reik, LM1
Ryan, DE1
Levin, W1
Kleeberg, U2
Klinger, W2
Kalland, T1
Forsberg, JG1
Watanabe, HK1
Matsui, M1
Förlin, L1
Pacifici, GM2
Davies, DS2
Whyte, C1
Boobis, AR2
Pickett, CB1
Jeter, RL1
Morin, J1
Lu, AY1
Hollingsworth, MA1
Barrowclough, J1
Evans, DL1
van Boxtel, CJ1
Rane, A2
Brown, RD1
Wilson, JT1
Zhu, BT1
Suchar, LA2
Gwynne, M1
Huang, MT1
Ziółkowska, M4
Nowak, JJ4
Janiak, M1
Ryzewska, A4
Coceani, F1
Kelsey, L1
Ackerley, C1
Rabinovitch, M1
Gelboin, H1
Rich, KJ1
Foster, JR1
Edwards, RJ1
Schilter, B1
Turesky, RJ1
Juillerat, M1
Honegger, P1
Guigoz, Y1
Viner, RI1
Kupchinskiĭ, AB1
Chang, RL1
Rosen, RT1
Lech, J1
Patel, HR1
Hewer, A1
Hayes, JD1
Phillips, DH1
Campbell, FC1
Morita, K1
Maeda, Y1
Masuda, M1
Kazusaka, A1
Imaoka, S1
Funae, Y1
Fujita, S1
Ronis, MJ1
Rowlands, JC1
Hakkak, R1
Badger, TM1
Matsunaga, N1
Hattori, K1
Iizasa, H1
Kizu, J1
Takanaka, A1
Nakashima, E1
Birnbaum, LS1
Baird, MB1
Hassall, KA1
Addala, SA1
Kluwe, WM1
McCormack, KM1
Hook, JB2
Nunnink, JC1
Chuang, AH1
Bresnick, E1
Poole, TW1
Parke, DV1
Pegg, DG1
Lambert, GH1
Thorgeirsson, SS1
Davies, DL1
Bryant, GM1
Arcos, JC1
Argus, MF1
Klaassen, CD2
Wiebel, FJ1
Gelboin, HV1
Oesch, F1
Powis, G1
Drummond, AH1
Macintyre, DE1
Jondorf, WR1
Peggins, JO1
McMahon, TF1
Weiner, M1
Lesko, L1
Horbach, GJ1
Van Asten, JG1
Rietjens, IM1
Kremers, P1
Van Bezooijen, CF1
Omiecinski, CJ1
Redlich, CA1
Costa, P1
Chasserot-Golaz, S1
Ribeiro, V1
Genot, G1
Lechner, MC1
Beck, G1
Símová, J1
Bubeník, J1
Voitenok, NN1
Gren, E1
Igarashi, T1
Irokawa, N1
Ono, S1
Ohmori, S1
Ueno, K1
Kitagawa, H1
Satoh, T1
Park, SS1
Gelboin, HW1
Wynne, H1
Mutch, E1
James, OF1
Rawlins, MD1
Woodhouse, KW1
Gulyaeva, LF1
Mishin, VM1
Lyakhovich, VV1
Manoharan, K1
Rao, AR1
Gielen, JE1
Goujon, FM1
Nebert, DW1
Yang, CS1
Strickhart, FS1
Oesch, E1
Jerina, DM1
Daly, J1
Huebner, RJ1
Schönharting, M1
Mende, G1
Siebert, G1
Sato, T1
Moroi, K1
Blumenthal, HT1
Rogers, JB1
Pollard, M1
Nery, R1
Stjernswärd, J1

Reviews

3 reviews available for 3-methylcholanthrene and Aging

ArticleYear
Identification of leukemogenic viruses: specifications for vertically transmitted, mostly 'switched off' RNA tumor viruses as determinants of the generality of cancer.
    Bibliotheca haematologica, 1970, Issue:36

    Topics: Aging; Animals; Antigens, Viral; Cats; Chickens; Embryo, Mammalian; Embryo, Nonmammalian; Genes; Gen

1970
Spontaneous and induced tumors in the guinea pig, with special reference to the factor of age.
    Progress in experimental tumor research, 1967, Volume: 9

    Topics: Aging; Animals; Chondrosarcoma; Fibrosarcoma; Guinea Pigs; Methylcholanthrene; Myxosarcoma; Neoplasm

1967
The germfree rat.
    Pathobiology annual, 1971, Volume: 1

    Topics: Adenocarcinoma; Adenofibroma; Aging; Animals; Animals, Newborn; Benz(a)Anthracenes; Female; Germ-Fre

1971

Other Studies

64 other studies available for 3-methylcholanthrene and Aging

ArticleYear
The skin of hairless mice. II. Ageing changes and the action of 20-methylcholanthrene.
    The Journal of investigative dermatology, 1954, Volume: 23, Issue:4

    Topics: Aging; Animals; Methylcholanthrene; Mice; Mice, Hairless; Neoplasms, Experimental; Skin

1954
On the factor of age in the production of subcutaneous sarcomas in mice by 20-methylcholanthrene.
    Journal of the National Cancer Institute, 1953, Volume: 14, Issue:3

    Topics: Aging; Animals; Methylcholanthrene; Mice; Neoplasms, Experimental; Sarcoma; Sarcoma, Experimental

1953
Effects of hormonal factors and of the hereditary character hairless on the sterols of mouse skin.
    Cancer research, 1956, Volume: 16, Issue:1

    Topics: Aging; Animals; Castration; Cholesterol; Methylcholanthrene; Mice; Skin; Sterols

1956
GROWTH PATTERN OF THE MOUSE PROSTATE GLAND IN ORGAN CULTURE AND ITS RESPONSE TO SEX HORMONES, VITAMIN A, AND 3-METHYLCHOLANTHRENE.
    National Cancer Institute monograph, 1963, Volume: 12

    Topics: Aging; Estradiol; Estrone; Gonadal Steroid Hormones; Humans; Male; Methylcholanthrene; Mice; Organ C

1963
AROMATIC-INDUCED PREVENTION OF FETAL TOXICITY OF 7,12-DIMETHYLBENZ(ALPHA)ANTHRACENE.
    The Journal of experimental medicine, 1964, Jan-01, Volume: 119

    Topics: Aging; Animals; Anthracenes; Benz(a)Anthracenes; DNA; Humans; Hydrocarbons; Liver; Male; Metabolism;

1964
DAMAGE TO THE THYMUS AND OTHER LYMPHOID TISSUES FROM 3-METHYLCHOLANTHRENE, AND SUBSEQUENT THYMOMA PRODUCTION, IN MICE.
    Cancer research, 1964, Volume: 24

    Topics: Aging; Body Weight; Electrons; Lung Neoplasms; Lymph Nodes; Lymphoid Tissue; Methylcholanthrene; Mic

1964
AGE AND SEX FACTORS IN EXPERIMENTAL BRAIN TUMORS.
    Surgical forum, 1964, Volume: 15

    Topics: Aging; Animals; Brain Abscess; Brain Neoplasms; Carcinoma, Squamous Cell; Glioblastoma; Glioma; Meth

1964
SIMILARITIES BETWEEN OXIDATIVE DRUG-METABOLIZING ENZYMES AND STEROID HYDROXYLASES IN LIVER MICROSOMES.
    The Journal of pharmacology and experimental therapeutics, 1964, Volume: 146

    Topics: Aging; Animals; Chlordan; Estradiol; Fatty Acids; Hexobarbital; Liver; Methylcholanthrene; Mice; Mic

1964
Age-dependent in situ hepatic and gill CYP1A activity in the see-through medaka (Oryzias latipes).
    Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2007, Volume: 145, Issue:1

    Topics: Aging; Animals; Cytochrome P-450 CYP1A1; Enzyme Induction; Female; Gills; Larva; Liver; Male; Methyl

2007
Induction studies of delta 1-tetrahydrocannabinol metabolism by rat and rabbit lungs.
    Comparative biochemistry and physiology. C: Comparative pharmacology, 1981, Volume: 69C, Issue:1

    Topics: Aging; Animals; Dronabinol; Enzyme Induction; Lung; Male; Methylcholanthrene; Mixed Function Oxygena

1981
Regulation of three forms of cytochrome P-450 and epoxide hydrolase in rat liver microsomes. Effects of age, sex, and induction.
    The Journal of biological chemistry, 1981, Jan-25, Volume: 256, Issue:2

    Topics: Aging; Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 Enzyme System; Cytochrome P450 Famil

1981
Glucose-6-phosphatase activities in the developing rat liver and kidney and after phenobarbital, 3-methylcholanthrene, and actinomycin D pretreatment.
    Zeitschrift fur Versuchstierkunde, 1984, Volume: 26, Issue:1

    Topics: Aging; Animals; Animals, Laboratory; Animals, Newborn; Dactinomycin; Glucose-6-Phosphatase; Kidney;

1984
3-methylcholanthrene: transient inhibition of the lytic step of mouse natural killer cells.
    Journal of the National Cancer Institute, 1983, Volume: 71, Issue:2

    Topics: Aging; Animals; Animals, Newborn; Cytotoxicity, Immunologic; Diethylstilbestrol; Killer Cells, Natur

1983
Rat liver sulfotransferases: effects of gonadal hormones and other factors on enzyme activities.
    Journal of pharmacobio-dynamics, 1984, Volume: 7, Issue:9

    Topics: Aging; Androsterone; Animals; Body Weight; Corticosterone; Cytosol; Estradiol; Gonadal Steroid Hormo

1984
Effects of clophen A50, 3-methylcholanthrene, pregnenolone-16 alpha-carbonitrile, and phenobarbital on the hepatic microsomal cytochrome P-450-dependent monooxygenase system in rainbow trout, Salmo gairdneri, of different age and sex.
    Toxicology and applied pharmacology, 1980, Volume: 54, Issue:3

    Topics: Aging; Animals; Benzopyrene Hydroxylase; Cytochrome P-450 Enzyme System; Female; Male; Methylcholant

1980
Age course and inducibility of dimethylnitrosamine N-demethylation in rat liver.
    Acta biologica et medica Germanica, 1982, Volume: 41, Issue:7-8

    Topics: Aging; Animals; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; Enzyme

1982
Tissue differences in the ontogeny of inducibility of drug-metabolizing enzymes by 3-methylcholanthrene in the rabbit.
    Xenobiotica; the fate of foreign compounds in biological systems, 1982, Volume: 12, Issue:9

    Topics: Aging; Animals; Enzyme Induction; Kidney; Liver; Lung; Methylcholanthrene; Organ Specificity; Rabbit

1982
Electroimmunochemical quantitation of cytochrome P-450, cytochrome P-448, and epoxide hydrolase in rat liver microsomes.
    The Journal of biological chemistry, 1981, Aug-25, Volume: 256, Issue:16

    Topics: Aging; Animals; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Cytochromes; Enzyme Inducti

1981
Age-related increases in mitogenic responses and natural immunity to a syngeneic fibrosarcoma in rats.
    Mechanisms of ageing and development, 1981, Volume: 17, Issue:1

    Topics: Aging; Animals; Cell Division; Concanavalin A; Fibrosarcoma; Immunity, Innate; Methylcholanthrene; M

1981
The formation of carbamazepine epoxide by rat liver microsomes: an investigation of the biphasic kinetic profile.
    Life sciences, 1981, Dec-21, Volume: 29, Issue:25

    Topics: Aging; Animals; Carbamazepine; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital;

1981
Effect of age and sex on the inducibility of hepatic microsomal 4-nitrophenol UDP-glucuronyltransferase activity in rats.
    Life sciences, 1995, Volume: 57, Issue:1

    Topics: Aging; Animals; Dexamethasone; Enzyme Induction; Female; Glucuronosyltransferase; Male; Methylcholan

1995
Recombinant tumor necrosis factor alpha inhibits growth of methylcholanthrene-induced sarcoma and enhances natural killer activity of tumor-infiltrating lymphocytes in aging rats.
    Archivum immunologiae et therapiae experimentalis, 1993, Volume: 41, Issue:5-6

    Topics: Adjuvants, Immunologic; Aging; Animals; Cell Division; Cytotoxicity, Immunologic; Killer Cells, Natu

1993
Cytochrome P450 during ontogenic development: occurrence in the ductus arteriosus and other tissues.
    Canadian journal of physiology and pharmacology, 1994, Volume: 72, Issue:3

    Topics: Aging; Animals; Animals, Newborn; Aorta; Cells, Cultured; Cytochrome P-450 Enzyme System; Dexamethas

1994
Ontogenetic development of the distribution of constitutive and 3-methylcholanthrene-induced CYP1A1 and CYP1A2 in rabbit liver.
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 1993, Volume: 41, Issue:6

    Topics: Aging; Animals; Blotting, Western; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Isoenzy

1993
Phase I and phase II xenobiotic reactions and metabolism of the food-borne carcinogen 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in aggregating liver cell cultures.
    Biochemical pharmacology, 1993, Mar-09, Volume: 45, Issue:5

    Topics: 7-Alkoxycoumarin O-Dealkylase; Aging; Animals; Cells, Cultured; Dimethyl Sulfoxide; Drug Synergism;

1993
[4-Androstene-3,17-dione metabolism in vitro in the liver microsomes of species of bullhead endemic to Lake Baikal under normal conditions and in mono-oxygenase induction by 3-methylcholanthrene and aroclor 1254].
    Nauchnye doklady vysshei shkoly. Biologicheskie nauki, 1993, Issue:1

    Topics: Aging; Androstenedione; Animals; Aroclors; Chlorodiphenyl (54% Chlorine); Enzyme Induction; Female;

1993
Effects of phenobarbital, dexamethasone, and 3-methylcholanthrene administration on the metabolism of 17 beta-estradiol by liver microsomes from female rats.
    Endocrinology, 1996, Volume: 137, Issue:2

    Topics: Aging; Animals; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Estradiol; Female;

1996
Age-dependent change of metabolic capacity and genotoxic injury in rat intestine.
    Chemico-biological interactions, 1998, May-01, Volume: 113, Issue:1

    Topics: Aging; Animals; Cytochrome P-450 Enzyme System; DNA Adducts; Enzyme Induction; Female; Glucuronosylt

1998
Strain differences in CYP3A-mediated C-8 hydroxylation (1,3,7-trimethyluric acid formation) of caffeine in Wistar and Dark Agouti rats. Rapid metabolism of caffeine in debrisoquine poor metabolizer model rats.
    Biochemical pharmacology, 1998, May-01, Volume: 55, Issue:9

    Topics: Aging; Animals; Aryl Hydrocarbon Hydroxylases; Caffeine; Cytochrome P-450 CYP3A; Cytochrome P-450 En

1998
Inducibility of hepatic CYP1A enzymes by 3-methylcholanthrene and isosafrole differs in male rats fed diets containing casein, soy protein isolate or whey from conception to adulthood.
    The Journal of nutrition, 2001, Volume: 131, Issue:4

    Topics: Aging; Animals; Blotting, Northern; Blotting, Western; Caseins; Cytochrome P-450 CYP1A1; Cytochrome

2001
Application of the PKCYP-test in cases of altered CYP1A2 for multiple CYP systems in rat models of disease.
    Biological & pharmaceutical bulletin, 2001, Volume: 24, Issue:9

    Topics: Acetanilides; Aging; Algorithms; Animals; Antibodies, Blocking; Caffeine; Central Nervous System Sti

2001
Induction of hepatic mixed function oxidases in senescent rodents.
    Experimental gerontology, 1978, Volume: 13, Issue:5

    Topics: Aging; Animals; Benzopyrene Hydroxylase; Benzphetamine; Biotransformation; Cytochrome P-450 Enzyme S

1978
Use of a dimethylated oxirane to characterise microsomal mono-oxygenases in rat liver.
    Biochemical pharmacology, 1979, Nov-01, Volume: 28, Issue:21

    Topics: Aging; Animals; Dieldrin; Enzyme Induction; Female; In Vitro Techniques; Male; Methylcholanthrene; M

1979
Chemical induction of p-aminohippuric acid transport in renal cortical slices from adult and immature rabbits.
    The Journal of pharmacology and experimental therapeutics, 1978, Volume: 205, Issue:3

    Topics: Aging; Aminohippuric Acids; Animals; Biological Transport, Active; Female; In Vitro Techniques; Kidn

1978
The ontogeny of nuclear aryl hydrocarbon hydroxylase.
    Chemico-biological interactions, 1978, Volume: 22, Issue:2-3

    Topics: Aging; Animals; Animals, Newborn; Aryl Hydrocarbon Hydroxylases; Cell Nucleus; Enzyme Induction; Fem

1978
Effects of age, inducing agents and carcinogens on the distribution of cytochrome P-450 in microsomal membranes from rat liver.
    Biochemical Society transactions, 1978, Volume: 6, Issue:5

    Topics: 2-Acetylaminofluorene; Aging; Animals; Carcinogens; Cytochrome P-450 Enzyme System; Male; Methylchol

1978
Glutathione S-transferases: an evaluation of their role in renal organic anion transport.
    The Journal of pharmacology and experimental therapeutics, 1977, Volume: 200, Issue:1

    Topics: Aging; Ammonium Chloride; Animals; Animals, Newborn; Anions; Biological Transport; Female; Glutathio

1977
Glutathione in the developing mouse liver--I. Developmental curve and depletion after acetaminophen treatment.
    Biochemical pharmacology, 1976, Aug-01, Volume: 25, Issue:15

    Topics: Acetaminophen; Aging; Animals; Female; Fetus; Glutathione; Liver; Methylcholanthrene; Mice; Mice, In

1976
Age-dependence of hepatic dimethylnitrosamine-demethylase activity in the rat.
    Journal of the National Cancer Institute, 1976, Volume: 56, Issue:5

    Topics: Aging; Animals; Dimethylnitrosamine; Liver; Male; Methylcholanthrene; Microsomes, Liver; Nitrosamine

1976
Biliary excretion of drugs: role of ligandin in newborn immaturity and in the action of microsomal enzyme inducers.
    The Journal of pharmacology and experimental therapeutics, 1975, Volume: 195, Issue:2

    Topics: Aging; Animals; Animals, Newborn; Bile; Biotransformation; Carrier Proteins; Enzyme Induction; Gluta

1975
Aryl hydrocarbon (benzo[a]pyrene) hydroxylases in liver from rats of different age, sex and nutritional status. Distinction of two types by 7,8-benzoflavone.
    Biochemical pharmacology, 1975, Aug-15, Volume: 24, Issue:16

    Topics: Aging; Animals; Animals, Newborn; Aryl Hydrocarbon Hydroxylases; Diet; Enzyme Induction; Female; Fla

1975
Differential control of rat microsomal "aryl hydrocarbon" monooxygenase and epoxide hydratase.
    The Journal of biological chemistry, 1976, Jan-10, Volume: 251, Issue:1

    Topics: Aging; Animals; Aryl Hydrocarbon Hydroxylases; Epoxide Hydrolases; Female; Fetus; Hydro-Lyases; Live

1976
Development of liver microsomal oxidations in the chick.
    Xenobiotica; the fate of foreign compounds in biological systems, 1976, Volume: 6, Issue:2

    Topics: Aging; Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Chickens; Cytochrome P-450 Enzyme Sy

1976
The effects of age on the pharmacokinetics and biotransformation of theophylline in vivo and in vitro in the Mongolian gerbil (Meriones unguiculatus).
    Mechanisms of ageing and development, 1992, Volume: 66, Issue:2

    Topics: Aging; Animals; Biotransformation; Cytochrome P-450 Enzyme System; Female; Gerbillinae; Half-Life; I

1992
The effect of age on inducibility of various types of rat liver cytochrome P-450.
    Xenobiotica; the fate of foreign compounds in biological systems, 1992, Volume: 22, Issue:5

    Topics: Aging; Animals; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Enzyme Induction; Enzyme-Li

1992
Induction and developmental expression of cytochrome P450IA1 messenger RNA in rat and human tissues: detection by the polymerase chain reaction.
    Cancer research, 1990, Jul-15, Volume: 50, Issue:14

    Topics: Aging; Animals; Base Sequence; Blotting, Northern; Blotting, Southern; Cytochrome P-450 Enzyme Syste

1990
Methylcholanthrene-induced tumors in adult and in aging rats: infiltrating cells and their ADCC activity.
    Archivum immunologiae et therapiae experimentalis, 1990, Volume: 38, Issue:3-4

    Topics: Aging; Animals; Antibody-Dependent Cell Cytotoxicity; Lymphocytes, Tumor-Infiltrating; Male; Methylc

1990
The steroid antagonist RU38486 is metabolized by the liver microsomal P450 mono-oxygenases.
    Biochemical and biophysical research communications, 1990, Mar-30, Volume: 167, Issue:3

    Topics: Aging; Animals; Antibodies; Biotransformation; Cytochrome P-450 Enzyme System; Kinetics; Liver; Male

1990
Chemoimmunotherapy of MC-induced mouse sarcomas with human recombinant interleukin 2 and cyclophosphamide: age-dependent decline of the therapeutic efficacy.
    Folia biologica, 1989, Volume: 35, Issue:3

    Topics: Aging; Animals; Cyclophosphamide; Humans; Immunotherapy; Interleukin-2; Male; Methylcholanthrene; Mi

1989
Difference in the effects of phenobarbital and 3-methylcholanthrene treatment on subunit composition of hepatic glutathione S-transferase in male and female rats.
    Xenobiotica; the fate of foreign compounds in biological systems, 1987, Volume: 17, Issue:2

    Topics: Aging; Animals; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Female; Glutathione Transfera

1987
Ontogenic development of 7-ethoxycoumarin and 7-ethoxyresorufin O-deethylase in the rat and effect of monoclonal antibodies.
    Pharmacology & toxicology, 1988, Volume: 62, Issue:2

    Topics: 7-Alkoxycoumarin O-Dealkylase; Aging; Animals; Antibodies, Monoclonal; Cytochrome P-450 CYP1A1; Cyto

1988
Activity of lymphocytes and antibodies derived from aging and adult rats bearing a MC-induced tumor in the syngeneic ADCC test.
    Neoplasma, 1987, Volume: 34, Issue:6

    Topics: Aging; Animals; Antibodies, Neoplasm; Antibody-Dependent Cell Cytotoxicity; Cytotoxicity Tests, Immu

1987
ADCC in aging rats with methylcholanthrene-induced sarcoma (MC-Sa).
    Archivum immunologiae et therapiae experimentalis, 1987, Volume: 35, Issue:6

    Topics: Aging; Animals; Antibody-Dependent Cell Cytotoxicity; Leukemia L1210; Lymphocytes; Male; Methylchola

1987
The effect of age on mono-oxygenase enzyme kinetics in rat liver microsomes.
    Age and ageing, 1987, Volume: 16, Issue:3

    Topics: Aging; Aldrin; Animals; Cytochrome P-450 Enzyme System; Enzyme Induction; In Vitro Techniques; Kinet

1987
Induction and catalytic activities of cytochromes P-450b/e and P-450c in the liver microsomes of neonatal rats.
    The International journal of biochemistry, 1986, Volume: 18, Issue:9

    Topics: Aging; Animals; Animals, Newborn; Cytochrome P-450 Enzyme System; Kinetics; Liver; Methylcholanthren

1986
Influence of age on experimental cervical carcinogenesis in mice.
    Indian journal of experimental biology, 1985, Volume: 23, Issue:10

    Topics: Aging; Animals; Cervix Uteri; Female; Methylcholanthrene; Mice; Uterine Cervical Neoplasms

1985
Genetic regulation of aryl hydrocarbon hydroxylase induction. II. Simple Mendelian expression in mouse tissues in vivo.
    The Journal of biological chemistry, 1972, Feb-25, Volume: 247, Issue:4

    Topics: Aging; Animals; Benzopyrenes; Carbon Monoxide; Crosses, Genetic; Cytochromes; Enzyme Induction; Fema

1972
Inhibition of hepatic mixed function oxidase activity by propyl gallate.
    Biochemical pharmacology, 1974, Nov-15, Volume: 23, Issue:22

    Topics: Aging; Aminopyrine N-Demethylase; Animals; Benzopyrenes; Benzphetamine; Cytochrome c Group; Cytochro

1974
A radiometric assay for hepatic epoxide hydrase activity with [7-3H] styrene oxide.
    Biochimica et biophysica acta, 1971, Mar-10, Volume: 227, Issue:3

    Topics: Aging; Animals; Cell Fractionation; Centrifugation; Chemical Phenomena; Chemistry; Chromatography, T

1971
Stimulation of the development of the hepatic excretory mechanism for ouabain in newborn rats with microsomal enzyme inducers.
    The Journal of pharmacology and experimental therapeutics, 1974, Volume: 191, Issue:2

    Topics: Aging; Animals; Animals, Newborn; Bile; Enzyme Induction; Liver; Methylcholanthrene; Microsomes, Liv

1974
Metabolic transformation of colchicine, II. The metabolism of colchicine by mammalian liver microsomes.
    Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1974, Volume: 355, Issue:11

    Topics: Aging; Animals; Colchicine; Cricetinae; Glucuronates; Liver; Methylcholanthrene; Mice; Microsomes, L

1974
Species differences in induction and inhibition of liver isocarboxazid hydrolase.
    Life sciences. Pt. 2: Biochemistry, general and molecular biology, 1973, Feb-22, Volume: 12, Issue:4

    Topics: Aging; Animals; Animals, Newborn; Enzyme Induction; Female; Guinea Pigs; Hydrolases; In Vitro Techni

1973
Some aspects of the metabolism of urethane and N-hydroxyurethane in rodents.
    The Biochemical journal, 1968, Volume: 106, Issue:1

    Topics: Aging; Animals; Animals, Newborn; Carbamates; Chloromercuribenzoates; Cyanides; Depression, Chemical

1968
Age-dependent tumor-host barrier and effect of carcinogen-induced immunodepression on rejection of isografted methylcholanthrene-induced sarcoma cells.
    Journal of the National Cancer Institute, 1966, Volume: 37, Issue:4

    Topics: Aging; Animals; Methylcholanthrene; Mice; Neoplasm Transplantation; Sarcoma, Experimental; Transplan

1966