3-methylcholanthrene has been researched along with Adenoma in 51 studies
Methylcholanthrene: A carcinogen that is often used in experimental cancer studies.
3-methylcholanthrene : A pentacyclic ortho- and peri-fused polycyclic arene consisting of a dihydrocyclopenta[ij]tetraphene ring system with a methyl substituent at the 3-position.
Adenoma: A benign epithelial tumor with a glandular organization.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Three spontaneous pulmonary adenomas of C mice, morphologically resembling those induced by methylcholanthrene or urethane, were propagated in host after host under conditions such that the neoplastic cells were directly exposed, while proliferating, to one or the other of these agents." | 7.63 | Are carcinogens responsible for the superimposed neoplastic changes occurring in mouse tumor cells? The effect of methylcholanthrene and urethane on pulmonary adenomas and of methylcholanthrene on mammary carcinomas. ( DUMBELL, K; ROUS, P, 1955) |
| " We show herein that resistant C57BL/6J (B6) and intermediately resistant BALB/cByJ (BALB) mice form very few urethane-induced early microadenomas (i." | 3.73 | Quantitative analysis of early chemically-induced pulmonary lesions in mice of varying susceptibilities to lung tumorigenesis. ( Dwyer-Nield, LD; Kisley, LR; Malkinson, AM; O'Donnell, EP; Zerbe, LK, 2006) |
| "Athymic-nude (nu/nu) mice and normal (nu/+) mice showed no differences in either latent period or incidence of local sarcomas or lung adenomas within 120 days after administration of 3-methylcholanthrene at birth." | 3.65 | Tumor development after 3-methylcholanthrene in immunologically deficient athymic-nude mice. ( Stutman, O, 1974) |
| "Three spontaneous pulmonary adenomas of C mice, morphologically resembling those induced by methylcholanthrene or urethane, were propagated in host after host under conditions such that the neoplastic cells were directly exposed, while proliferating, to one or the other of these agents." | 3.63 | Are carcinogens responsible for the superimposed neoplastic changes occurring in mouse tumor cells? The effect of methylcholanthrene and urethane on pulmonary adenomas and of methylcholanthrene on mammary carcinomas. ( DUMBELL, K; ROUS, P, 1955) |
| " DMBA led to a marked predominance of squamous celled tumours (SQCT) when treatment was potent, while basal celled and adnexal tumours (BCAT) prevailed after any dosage of MCA." | 1.27 | Skin carcinogenesis in rats by 3-methylcholanthrene and 7,12-dimethylbenz(alpha)anthracene. Influence of dose and frequency on tumour response and its histological type. ( Arffmann, E; Glenthøj, A; Rasmussen, KS, 1983) |
| " The dosing schedule and total dose of DMN or MCA or DMN + MCA received were identical to those used by other investigators in their syncarcinogenesis bioassay study in Swiss mice." | 1.26 | Comparative pulmonary tumorigenesis in DBA/2J and C57Bl/6J mice by administration of 3-methylcholanthrene and dimethylnitrosamine singly and combined. ( Arcos, JC; Argus, MF; Hoch-Ligeti, C, 1982) |
| "These neoplasms included cholangiomas, hepatoadenomas, cholangiocarcinomas, and hepatocellular cancers." | 1.25 | Tumor induction by carcinogenic agents in aquarium fish. ( Khudoley, VV; Pliss, GB, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 44 (86.27) | 18.7374 |
| 1990's | 3 (5.88) | 18.2507 |
| 2000's | 4 (7.84) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Efeyan, A | 1 |
| Murga, M | 1 |
| Martinez-Pastor, B | 1 |
| Ortega-Molina, A | 1 |
| Soria, R | 1 |
| Collado, M | 1 |
| Fernandez-Capetillo, O | 1 |
| Serrano, M | 1 |
| JAFFE, WG | 1 |
| DUMBELL, K | 1 |
| ROUS, P | 1 |
| MIYOSHI, I | 1 |
| GROSS, P | 1 |
| POEL, W | 1 |
| HAYASHI, N | 1 |
| NISHIZUKA, Y | 1 |
| NAKAKUKI, K | 1 |
| DANIEL, PM | 1 |
| PRICHARD, MM | 1 |
| KITAMURA, H | 1 |
| CAMPBELL, JS | 1 |
| YANG, YH | 1 |
| BOLTON, JD | 1 |
| ZAWIRSKA, B | 1 |
| HOWES, L | 1 |
| de OLIVEIRA, JR | 1 |
| O'Donnell, EP | 1 |
| Zerbe, LK | 1 |
| Dwyer-Nield, LD | 1 |
| Kisley, LR | 1 |
| Malkinson, AM | 2 |
| Wang, IC | 1 |
| Meliton, L | 1 |
| Tretiakova, M | 1 |
| Costa, RH | 1 |
| Kalinichenko, VV | 1 |
| Kalin, TV | 1 |
| Wrba, H | 1 |
| Rasmussen, KS | 1 |
| Glenthøj, A | 1 |
| Arffmann, E | 1 |
| Suzuki, A | 1 |
| Takahashi, T | 1 |
| Argus, MF | 1 |
| Hoch-Ligeti, C | 1 |
| Arcos, JC | 1 |
| Hirao, F | 1 |
| Sakatani, M | 1 |
| Nishikawa, H | 1 |
| Yoshimoto, T | 1 |
| Namba, M | 1 |
| Ogura, T | 1 |
| Azuma, I | 1 |
| Yamamura, Y | 1 |
| Fernandez, PL | 1 |
| Cardesa, A | 2 |
| Kamino, K | 1 |
| Miller, MS | 1 |
| Gressani, KM | 1 |
| Leone-Kabler, S | 1 |
| Townsend, AJ | 1 |
| O'Sullivan, MG | 1 |
| Furst, A | 1 |
| van Breda Kolff, K | 1 |
| Dempsey, DA | 1 |
| Pliss, GB | 1 |
| Khudoley, VV | 1 |
| Matsushima, T | 1 |
| Sugimura, T | 1 |
| Kinoshita, K | 1 |
| Takahashi, G | 1 |
| Yasuhira, K | 2 |
| Vlasov, V | 1 |
| Uzunov, P | 1 |
| Balanski, RM | 1 |
| Dzhioev, FK | 1 |
| He, R | 1 |
| Gunning, WT | 1 |
| Castonguay, A | 1 |
| Goldblatt, PJ | 1 |
| Stoner, GD | 2 |
| Pour, P | 1 |
| Rustia, M | 1 |
| Althoff, J | 1 |
| Mohr, U | 1 |
| Middleton, PJ | 1 |
| Roe, FJ | 1 |
| Walters, MA | 1 |
| Flaks, B | 3 |
| Flaks, A | 5 |
| Gardner, MB | 1 |
| Officer, JE | 1 |
| Rongey, RW | 1 |
| Estes, JD | 1 |
| Turner, HC | 1 |
| Huebner, RJ | 2 |
| Squartini, F | 1 |
| Bolis, GB | 1 |
| Anisimov, VN | 1 |
| Ito, N | 1 |
| Hiasa, Y | 1 |
| Kamakoto, Y | 1 |
| Makiura, S | 1 |
| Sugihara, S | 1 |
| Salerno, RA | 1 |
| Whitmire, CE | 1 |
| Garcia, IM | 1 |
| Akamatsu, Y | 1 |
| Barton, BP | 1 |
| Kniazeff, AJ | 1 |
| Shimkin, MB | 1 |
| Hoppenstand, RD | 1 |
| Stutman, O | 1 |
| Diamond, L | 1 |
| McFall, R | 1 |
| Miller, J | 1 |
| Gelboin, HV | 1 |
| Krieg, K | 1 |
| Davies, RF | 1 |
| Major, IR | 1 |
| Aberdeen, ER | 1 |
| Wheatley, DN | 1 |
| Laws, JO | 2 |
| Enomoto, M | 1 |
| Miyake, M | 1 |
| Sato, K | 1 |
3 reviews available for 3-methylcholanthrene and Adenoma
| Article | Year |
|---|---|
Tumours of the mammary gland.
Topics: Adenoma; Animals; Carcinoma; Cricetinae; Cystadenoma; Female; Fibroadenoma; Male; Mammary Glands, An | 1996 |
Differential sensitivity to lung tumorigenesis following transplacental exposure of mice to polycyclic hydrocarbons, heterocyclic amines, and lung tumor promoters.
Topics: Adenocarcinoma; Adenoma; Animals; Aryl Hydrocarbon Hydroxylases; Butylated Hydroxytoluene; Carcinoge | 2000 |
Experimental carcinogenesis in small aquarium fishes.
Topics: 2-Acetylaminofluorene; Adenoma; Adenoma, Bile Duct; Aflatoxins; Animals; Benzopyrenes; Carcinogens; | 1976 |
48 other studies available for 3-methylcholanthrene and Adenoma
| Article | Year |
|---|---|
Limited role of murine ATM in oncogene-induced senescence and p53-dependent tumor suppression.
Topics: Adenoma; Animals; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cellular Senescence; | 2009 |
Possible linkage between the development of local tumors and pulmonary adenomas induced by methyl-cholanthrene in non-inbred mice.
Topics: Adenoma; Animals; Benz(a)Anthracenes; Lung; Lung Neoplasms; Methylcholanthrene; Mice; Mice, Inbred S | 1947 |
Are carcinogens responsible for the superimposed neoplastic changes occurring in mouse tumor cells? The effect of methylcholanthrene and urethane on pulmonary adenomas and of methylcholanthrene on mammary carcinomas.
Topics: Adenoma; Animals; Breast Neoplasms; Carcinogens; Humans; Lung; Lung Neoplasms; Methylcholanthrene; M | 1955 |
ACCELERATION OF THE DEVELOPMENT OF LEUKEMIA AND INDUCTION OF TUMORS IN AKR MICE BY NEONATAL INJECTION OF 20-METHYLCHOLANTHRENE.
Topics: Adenoma; Animals; Carcinogens; Leukemia; Leukemia, Experimental; Leukemia, Lymphoid; Lung Neoplasms; | 1963 |
PULMONARY ADENOMA. THE FIBROGENIC POTENTIAL OF ITS EPITHELIUM.
Topics: Adenoma; Epithelium; Lung Neoplasms; Methylcholanthrene; Mice; Neoplasms; Neoplasms, Experimental; P | 1964 |
[ELECTRON MICROSCOPIC STUDIES ON THE EXPERIMENTAL LUNG TUMOR IN MOUSE].
Topics: Adenoma; Animals; Electrons; Lung Neoplasms; Methylcholanthrene; Mice; Microscopy; Microscopy, Elect | 1963 |
EFFECT OF 20-METHYLCHOLANTHRENE GIVEN AT BIRTH ON TUMOR DEVELOPMENT IN TWO HIGH-LEUKEMIA STRAINS OF MICE, AKR AND SL.
Topics: Adenoma; Animals; Animals, Newborn; Histology; Injections, Subcutaneous; Leukemia; Leukemia, Experim | 1964 |
PRODUCTION OF MAMMARY TUMOURS WITH 3-METHYLCHOLANTHRENE.
Topics: Adenofibroma; Adenoma; Animals; Breast Neoplasms; Humans; Mammary Neoplasms, Animal; Mammary Neoplas | 1964 |
THE FINE STRUCTURE OF LUNG ALVEOLI AND ITS REACTIONS. (HISTOPATHOLOGICAL STUDIES BY ELECTRON MICROSCOPE).
Topics: Adenoma; Animals; Antigen-Antibody Reactions; Cholesterol; Electrons; Encephalitis; Encephalitis Vir | 1964 |
MURINE LUNG ADENOMAS INDUCED BY INTRAVAGINAL CARCINOGEN.
Topics: Adenoma; Animals; Carcinogens; Female; Humans; Lung Neoplasms; Methylcholanthrene; Mice; Neoplasms; | 1965 |
MICROFLUOROSCOPIC STUDIES ON PORPHYRINS IN HARDER'S GLAND AND IN TUMORS INDUCED IN IT. II. MICROFLUOROSCOPIC STUDIES ON PORPHYRINS IN PRECANCEROUS STATES AND TUMORS INDUCED WITH METHYLCHOLANTHRENE IN HARDER'S GLAND IN WHITE RATS.
Topics: Adenoma; Animals; Carcinogens; Eye Neoplasms; Fluorescence; Histocytochemistry; Lacrimal Apparatus; | 1965 |
[Early modifications in the experimental production of adenomas and adenocarcinomas of the stomach].
Topics: Adenocarcinoma; Adenoma; Humans; Methylcholanthrene; Stomach | 1951 |
Quantitative analysis of early chemically-induced pulmonary lesions in mice of varying susceptibilities to lung tumorigenesis.
Topics: Adenoma; Animals; Butylated Hydroxytoluene; Cell Transformation, Neoplastic; Disease Susceptibility; | 2006 |
Transgenic expression of the forkhead box M1 transcription factor induces formation of lung tumors.
Topics: Adenoma; Animals; Butylated Hydroxytoluene; Cyclooxygenase 2; DNA Replication; Forkhead Box Protein | 2008 |
Experimental cancer prophylaxis.
Topics: Adenoma; Animals; Diterpenes; Ethylnitrosourea; Female; Fetus; Leukemia, Experimental; Lung Neoplasm | 1983 |
Skin carcinogenesis in rats by 3-methylcholanthrene and 7,12-dimethylbenz(alpha)anthracene. Influence of dose and frequency on tumour response and its histological type.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Animals; Benz(a)Anthracenes; Carcinoma; Carcinoma, Basal | 1983 |
Histogenesis of the gallbladder carcinoma induced by methylcholanthrene beeswax pellets in hamsters.
Topics: Adenocarcinoma; Adenoma; Animals; Carcinoma; Cricetinae; Gallbladder Neoplasms; Methylcholanthrene; | 1983 |
Comparative pulmonary tumorigenesis in DBA/2J and C57Bl/6J mice by administration of 3-methylcholanthrene and dimethylnitrosamine singly and combined.
Topics: Adenoma; Animals; Dimethylnitrosamine; Lung Neoplasms; Male; Methylcholanthrene; Mice; Mice, Inbred | 1982 |
Effect of Nocardia rubra cell-wall skeleton on the induction of lung cancer and amyloidosis by 3-methylcholanthrene in rabbits.
Topics: Adenoma; Amyloidosis; Animals; Cell Wall; Female; Hyperplasia; Immunization; Lung Neoplasms; Male; M | 1980 |
Pulmonary tumor induction: three hydrocarbons compared.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Animals; Benz(a)Anthracenes; Benzopyrenes; Carcinogens; F | 1979 |
Tumor induction by carcinogenic agents in aquarium fish.
Topics: 2-Acetylaminofluorene; 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenoma; Adenoma, Bile Duct | 1975 |
Lung tumors in mice suckled by 3-methylcholanthrene-treated mothers.
Topics: Adenocarcinoma; Adenoma; Animals; Animals, Suckling; Female; Lung Neoplasms; Male; Methylcholanthren | 1979 |
[Early changes in transplants of lung organ cultures treated with several polycyclic hydrocarbons].
Topics: Adenoma; Animals; Benzopyrenes; Bronchial Diseases; Carcinoma; Cysts; Hyperplasia; Lung; Lung Neopla | 1976 |
[The relationship between the activity of microsomal enzymes and pulmonary carcinogenesis in mice].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Animals; Antineoplastic Agents; Barbital; Chlorpromazine; | 1976 |
[Precancerous and cancerous lesions and their gamma-glutamyl transpeptidase expression in 3-methylcholanthrene-induced lung carcinogenesis in rats].
Topics: Adenoma; Animals; Biomarkers, Tumor; Carcinoma, Squamous Cell; gamma-Glutamyltransferase; Lung Neopl | 1991 |
Strain A/J mouse lung adenoma growth patterns vary when induced by different carcinogens.
Topics: 1,2-Dimethylhydrazine; Adenoma; Aflatoxins; Animals; Benzo(a)pyrene; Carcinogens; Cell Transformatio | 1991 |
The syncarcinogenic effect of methylcholanthrene and dimethylnitrosamine in Swiss mice.
Topics: Adenocarcinoma; Adenoma; Animals; Carcinogens; Carcinoma; Drug Synergism; Female; Kidney Neoplasms; | 1973 |
The histogenesis of mammary tumours induced in the rat by chemical carcinogens.
Topics: Adenofibroma; Adenoma; Animals; Benz(a)Anthracenes; Carcinoma, Intraductal, Noninfiltrating; Female; | 1965 |
Sensitivity of newborn mice to carcinogenic agents.
Topics: Adenocarcinoma; Adenoma; Animals; Animals, Newborn; Benz(a)Anthracenes; Carcinogens; Carcinoma, Hepa | 1968 |
Fine structure of nuclear inclusions in murine pulmonary tumor cells.
Topics: Adenocarcinoma; Adenoma; Animals; Cytoplasmic Granules; Inclusion Bodies; Lung Neoplasms; Methylchol | 1970 |
C-type RNA tumour virus genome expression in wild house mice.
Topics: Adenoma; Animals; Antigens; Antigens, Neoplasm; Carcinoma; Carcinoma, Squamous Cell; Complement Fixa | 1971 |
[Methylcholanthrene sensitivity of epithelial tissues of the respiratory tract in BALB-c-Cb-Se mice].
Topics: Adenocarcinoma, Bronchiolo-Alveolar; Adenoma; Animals; Bronchial Neoplasms; Epithelium; Lung Neoplas | 1971 |
[Blastomogenesis in rats with persistent estrus].
Topics: Adenocarcinoma; Adenofibroma; Adenoma; Adrenal Gland Neoplasms; Animals; Carcinoma, Squamous Cell; E | 1971 |
Histopathological analysis of kidney tumors in rats induced by chemical carcinogens.
Topics: Adenocarcinoma; Adenoma; Animals; Carcinogens; Carcinoma, Squamous Cell; Carcinoma, Transitional Cel | 1971 |
Chemical carcinogenesis in mice inhibited by interferon.
Topics: Adenoma; Animals; Antigens, Viral; Cell Transformation, Neoplastic; Female; Fibrosarcoma; Interferon | 1972 |
Electron-microscope observations on the formation of the cytoplasmic lamellar inclusion bodies in murine pulmonary tumours induced in vitro.
Topics: Adenocarcinoma; Adenoma; Animals; Cytoplasm; Glycogen; Golgi Apparatus; Inclusion Bodies; Lung Neopl | 1972 |
Neoplasms and amyloidosis in strains of mice treated with 3-methylcholanthrene.
Topics: Adenoma; Amyloidosis; Animals; Carcinoma, Hepatocellular; Carcinoma, Squamous Cell; Female; Liver Ne | 1974 |
Suppression of chemically induced pulmonary tumors by treatment of strain A mice with murine sarcoma virus.
Topics: Adenoma; Animals; Female; Gammaretrovirus; Lung Neoplasms; Male; Methylcholanthrene; Mice; Mice, Inb | 1974 |
Tumor development after 3-methylcholanthrene in immunologically deficient athymic-nude mice.
Topics: Adenoma; Animals; Female; Fibrosarcoma; Graft Rejection; Immunologic Deficiency Syndromes; Lung Neop | 1974 |
The effects of two isomeric benzoflavones on aryl hydrocarbon hydroxylase and the toxicity and carcinogenicity of polycyclic hydrocarbons.
Topics: Adenoma; Adrenal Gland Diseases; Animals; Benz(a)Anthracenes; Benzopyrenes; Benzyl Compounds; Cells, | 1972 |
[Experimental carcinogenesis in mollusca. 2. Transplantation experiments with a chemically-induced adenopapilloma in a La-Plata apple snail, Ampullarius australis d'Orbigny (Gastropoda,Prosobranchia)].
Topics: Adenocarcinoma; Adenoma; Animals; Croton Oil; Cystadenoma; Methylcholanthrene; Neoplasm Metastasis; | 1969 |
Pulmonary adenomata induced by carcinogen treatment in organ culture. Influence of increasing amounts of carcinogen.
Topics: Adenoma; Animals; Culture Techniques; Female; Lung Neoplasms; Male; Methylcholanthrene; Mice; Neopla | 1970 |
Experimental induction of lung cancer in rat and mouse with 20-methylcholanthrene in Freund's adjuvant.
Topics: Adenocarcinoma; Adenoma; Animals; Carcinoma, Squamous Cell; Female; Fluorometry; Freund's Adjuvant; | 1967 |
Enhancement and inhibition of the induction by 7,12-dimethylbenz(a)anthracene of mammary tumours in female Sprague-Dawley rats.
Topics: Adenocarcinoma; Adenofibroma; Adenoma; Animals; Anthracenes; Benz(a)Anthracenes; Fibroma; Mammary Ne | 1968 |
Pulmonary adenomata induced by carcinogen treatment in organ culture. Influence of duration of treatment.
Topics: Adenoma; Animals; Carcinoma; Culture Techniques; Lung Neoplasms; Methylcholanthrene; Mice; Neoplasm | 1968 |
Carcinogenicity in the hamster of simultaneously administered 2-acetamidofluorene and 3-methylcholanthrene.
Topics: Adenoma; Animals; Bile Duct Neoplasms; Body Weight; Carcinoma; Cricetinae; Fluorenes; Liver; Liver N | 1968 |
Fine structure of murine pulmonary adenomata induced by carcinogen treatment in organ culture.
Topics: Adenoma; Animals; Lung Neoplasms; Methylcholanthrene; Mice; Microscopy, Electron | 1969 |
Pulmonary adenomata induced by carcinogen treatment in organ culture.
Topics: Adenoma; Animals; Culture Techniques; Lung; Lung Neoplasms; Methylcholanthrene; Mice | 1966 |