3-methylcholanthrene has been researched along with Acute Disease in 4 studies
Methylcholanthrene: A carcinogen that is often used in experimental cancer studies.
3-methylcholanthrene : A pentacyclic ortho- and peri-fused polycyclic arene consisting of a dihydrocyclopenta[ij]tetraphene ring system with a methyl substituent at the 3-position.
Acute Disease: Disease having a short and relatively severe course.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The induction with 20-methylcholanthrene, glutathione depletion with buthionine sulfoxime, and subcutaneous administration of acetaminophen have led to the development of an animal model that parallels clinical, biochemical, and histological features of human hepatic failure." | 7.71 | A novel model of acetaminophen-induced acute hepatic failure in rabbits. ( Hodgson, HJ; Rahman, TM; Selden, AC, 2002) |
| "The induction with 20-methylcholanthrene, glutathione depletion with buthionine sulfoxime, and subcutaneous administration of acetaminophen have led to the development of an animal model that parallels clinical, biochemical, and histological features of human hepatic failure." | 3.71 | A novel model of acetaminophen-induced acute hepatic failure in rabbits. ( Hodgson, HJ; Rahman, TM; Selden, AC, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rahman, TM | 1 |
| Selden, AC | 1 |
| Hodgson, HJ | 1 |
| Kravchenko, LV | 1 |
| Avren'eva, LI | 1 |
| Tutel'ian, VA | 1 |
| Angelov, EP | 1 |
| Elgadi, KM | 1 |
| Souba, WW | 1 |
| Bode, BP | 1 |
| Abcouwer, SF | 1 |
4 other studies available for 3-methylcholanthrene and Acute Disease
| Article | Year |
|---|---|
A novel model of acetaminophen-induced acute hepatic failure in rabbits.
Topics: Acetaminophen; Acute Disease; Animals; Antimetabolites; Buthionine Sulfoximine; Disease Models, Anim | 2002 |
[Mechanism of the protective effect of modifiers of the liver enzyme systems metabolyzing xenobiotics in acute T-2 mycotoxicosis].
Topics: Acute Disease; Animals; Cobalt; Drug Evaluation, Preclinical; Enzyme Induction; Inactivation, Metabo | 1984 |
[A selective decrease in cytochrome P450 in the liver microsomes of male rats following phenobarbital and 3-methylcholanthrene induction and acute tetrachloromethane poisoning].
Topics: Acute Disease; Animals; Carbon Tetrachloride Poisoning; Cytochrome P-450 Enzyme System; Cytochromes | 1993 |
Hepatic glutaminase gene expression in the tumor-bearing rat.
Topics: Acute Disease; Animals; Fibrosarcoma; Gene Expression; Glucose; Glutaminase; Insulin; Liver; Male; M | 1997 |