3-methylcholanthrene has been researched along with Abnormalities, Drug-Induced in 14 studies
Methylcholanthrene: A carcinogen that is often used in experimental cancer studies.
3-methylcholanthrene : A pentacyclic ortho- and peri-fused polycyclic arene consisting of a dihydrocyclopenta[ij]tetraphene ring system with a methyl substituent at the 3-position.
Abnormalities, Drug-Induced: Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Time-mated Swiss-Webster mice were pretreated in separate experiments with phenobarbital (60 mg/kg X d sc on d 7-10 of pregnancy), SKF-525A (40 mg/kg ip on d 12 of pregnancy) or 3-methylcholanthrene (20 mg/kg X d on d 10-12 of pregnancy)." | 3.67 | Ethylenethiourea-induced hindpaw deformities in mice and effects of metabolic modifiers on their occurrence. ( Khera, KS, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (85.71) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Arzuaga, X | 1 |
| Elskus, A | 1 |
| KODIKAL, LG | 1 |
| BATRA, BK | 1 |
| Khera, KS | 1 |
| Greenaway, JC | 2 |
| Fantel, AG | 2 |
| Shepard, TH | 2 |
| Juchau, MR | 3 |
| Khlood, EB | 1 |
| Miyoshi, H | 1 |
| Iwata, H | 1 |
| Kazusaka, A | 1 |
| Kon, Y | 1 |
| Hadid, AH | 1 |
| Moustafe, EK | 1 |
| Ghonim, MH | 1 |
| Fujita, S | 1 |
| Nebert, DW | 4 |
| Shum, S | 1 |
| Boobis, AR | 1 |
| Atlas, SA | 1 |
| Lambert, GH | 3 |
| Levitt, RC | 1 |
| Jensen, NM | 1 |
| Felton, JS | 1 |
| Thorgeirsson, SS | 1 |
| Harris, C | 1 |
| Stark, KL | 1 |
| Luchtel, DL | 1 |
| Giachelli, CM | 1 |
| Faustman-Watts, EM | 1 |
| Matos, EL | 2 |
| de Lustig, ES | 2 |
| Foster, JA | 1 |
14 other studies available for 3-methylcholanthrene and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
Polluted-site killifish (Fundulus heteroclitus) embryos are resistant to organic pollutant-mediated induction of CYP1A activity, reactive oxygen species, and heart deformities.
Topics: Abnormalities, Drug-Induced; Animals; Cytochrome P-450 CYP1A1; Embryo, Nonmammalian; Enzyme Inductio | 2010 |
FURTHER STUDIES ON THE EFFECT OF METHYLCHOLANTHRENE ON OVARIES OF MICE.
Topics: Abnormalities, Drug-Induced; Female; Humans; Methylcholanthrene; Mice; Ovary; Research; Toxicology | 1965 |
Ethylenethiourea-induced hindpaw deformities in mice and effects of metabolic modifiers on their occurrence.
Topics: Abnormalities, Drug-Induced; Animals; Cytochrome P-450 Enzyme System; Ethylenethiourea; Female; Foot | 1984 |
The in vitro teratogenicity of cyclophosphamide in rat embryos.
Topics: Abnormalities, Drug-Induced; Animals; Aroclors; Brain; Chlorodiphenyl (54% Chlorine); Culture Techni | 1982 |
Effects of concurrent exposure to 3-methylcholanthrene and vitamin A on fetal development in rats.
Topics: Abnormalities, Drug-Induced; Animals; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Femal | 1999 |
Developmental pharmacology and the Ah locus: regulatory and temporal genes affecting teratogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Abnormalities, Drug-Induced; Alleles; Animals; Animals, Newborn; A | 1979 |
Genetically mediated induction of drug-metabolizing enzymes associated with congenital defects in the mouse.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Ary | 1977 |
Birth defects and aplastic anemia: differences in polycyclic hydrocarbon toxicity associated with the Ah locus.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Abnormalities, Drug-Induced; Alleles; Anemia, Aplastic; Animals; A | 1977 |
Genetic aspects of toxicity during development.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Abnormalities, Drug-Induced; Acetaminophen; Alleles; Animals; Aryl | 1976 |
Abnormal neurulation induced by 7-hydroxy-2-acetylaminofluorene and acetaminophen: evidence for catechol metabolites as proximate dysmorphogens.
Topics: 2-Acetylaminofluorene; Abnormalities, Drug-Induced; Acetaminophen; Animals; Biological Availability; | 1989 |
Effects of 3-methylcholanthrene and phenobarbital on the capacity of embryos to bioactivate teratogens during organogenesis.
Topics: 2-Acetylaminofluorene; Abnormalities, Drug-Induced; Animals; Biotransformation; Cyclophosphamide; Em | 1985 |
Teratogenic effects of carcinogen implantation in a regenerative field in Bufo arenarum tadpoles.
Topics: Abnormalities, Drug-Induced; Animals; Benz(a)Anthracenes; Benzopyrenes; Bufo arenarum; Carcinogens; | 1973 |
Teratogenic effects induced in tail of Bufo arenarum tadpoles following treatment with carcinogens.
Topics: Abnormalities, Drug-Induced; Animals; Benz(a)Anthracenes; Benzopyrenes; Bufo arenarum; Embryo, Nonma | 1971 |
Malformations and lethal growths in planaria treated with carcinogens.
Topics: Abnormalities, Drug-Induced; Benz(a)Anthracenes; Benzopyrenes; Carcinogens; Methylcholanthrene; Neop | 1969 |