3-methylcholanthrene has been researched along with Abnormalities, Autosome in 46 studies
Methylcholanthrene: A carcinogen that is often used in experimental cancer studies.
3-methylcholanthrene : A pentacyclic ortho- and peri-fused polycyclic arene consisting of a dihydrocyclopenta[ij]tetraphene ring system with a methyl substituent at the 3-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Light microscopic study of the evolution of 3-methylcholanthrene-induced mammary tumors in Wistar-Furth rats revealed a seriation of changes proceeding from early hyperplasia (8 days) to advanced hyperplasia (57 days) and cancer (78 days)." | 7.65 | Relationship of hyperplasia to cancer in 3-methylcholanthrene-induced mammary tumorogenesis. ( Fisher, ER; Sabnis, A; Shoemaker, RH, 1975) |
| "A 3-Methylcholanthrene (MC)-induced fibrosarcoma and three of its clones were investigated for their metastatic potential in normal and tumor immune mice." | 3.67 | The effect of immunity on pulmonary metastasis of a methylcholanthrene-induced fibrosarcoma and three of its clones. ( McKhann, CF; Wang, N; Yu, S, 1984) |
| "Rhabdomyosarcomas were induced in mice by intramuscular injections of crystalline nickel sulfide and 3-methylcholanthrene." | 3.67 | Chromosomal changes in cell lines from mouse tumors induced by nickel sulfide and methylcholanthrene. ( Biggart, NW; Christie, NT; Murphy, EC; Tummolo, DM, 1988) |
| "Light microscopic study of the evolution of 3-methylcholanthrene-induced mammary tumors in Wistar-Furth rats revealed a seriation of changes proceeding from early hyperplasia (8 days) to advanced hyperplasia (57 days) and cancer (78 days)." | 3.65 | Relationship of hyperplasia to cancer in 3-methylcholanthrene-induced mammary tumorogenesis. ( Fisher, ER; Sabnis, A; Shoemaker, RH, 1975) |
| "Benzo[a]pyrene (BP) induced aneuploidy at 2." | 1.30 | Aneuploidy induction by benzo[a]pyrene and polyploidy induction by 7,12-dimethylbenz[a]anthracene in Chinese hamster cell lines V79-MZ and V79. ( Glatt, HR; Hayashi, M; Matsuoka, A; Ozaki, M; Sakamoto, H; Sofuni, T; Takeshita, K, 1997) |
| "Bropirimine is an immunomodulator and has been investigated as an antineoplastic drug as well as for antiviral indications." | 1.28 | Comparative mutagenicity testing of bropirimine, 2. Further characterization and mechanistic investigation of clastogenesis. ( Aaron, CS; Donarski, WJ; Kumaroo, PV; Petry, TW; Thilagar, A; Ulrich, RG, 1991) |
| "Thus, the tumorigenic transformation of HUC resulted from the combined actions of SV40 and MCA." | 1.27 | Neoplastic transformation of SV40-immortalized human urinary tract epithelial cells by in vitro exposure to 3-methylcholanthrene. ( Christian, BJ; Loretz, LJ; Meisner, LF; Reznikoff, CA; Wu, SQ, 1988) |
| " The induction rate of CA in the cells of the fish species exposed to the chemicals tested for 48 hr clearly shows not only an increase in the CA frequency in a dose-response manner above the control, but also a species response dependency." | 1.27 | Carcinogenic-mutagenic chemicals induced chromosomal aberrations in the kidney cells of three cyprinids. ( Al-Sabti, K, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 42 (91.30) | 18.7374 |
| 1990's | 3 (6.52) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (2.17) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Harvey, RG | 1 |
| Cortez, C | 1 |
| Sugiyama, T | 1 |
| Ito, Y | 1 |
| Sawyer, TW | 1 |
| DiGiovanni, J | 1 |
| Mukherjee, S | 1 |
| Manna, S | 1 |
| Pal, D | 1 |
| Mukherjee, P | 1 |
| Panda, CK | 1 |
| DUNN, GD | 1 |
| MOLONEY, WC | 1 |
| REES, ED | 2 |
| MUKERJEE, D | 1 |
| Nachtigal, M | 1 |
| Popescu, NC | 5 |
| Nachtigal, S | 1 |
| Cassingena, R | 1 |
| Suarez, H | 1 |
| Kocan, RM | 1 |
| Landolt, ML | 1 |
| Sabo, KM | 1 |
| Kochhar, TS | 1 |
| Yu, S | 1 |
| Wang, N | 1 |
| McKhann, CF | 1 |
| Yosida, TH | 1 |
| Matsuoka, A | 1 |
| Ozaki, M | 1 |
| Takeshita, K | 1 |
| Sakamoto, H | 1 |
| Glatt, HR | 1 |
| Hayashi, M | 1 |
| Sofuni, T | 1 |
| Lin, MS | 1 |
| Davidson, RL | 1 |
| Klein, G | 1 |
| Klein, E | 1 |
| Lafond, MG | 1 |
| Calabrese, EJ | 1 |
| Turnbull, D | 1 |
| DiPaolo, JA | 4 |
| Weinstein, D | 1 |
| Katz, ML | 1 |
| Kazmer, S | 1 |
| Levan, O | 1 |
| Levan, A | 1 |
| Indo, K | 1 |
| Bempong, MA | 1 |
| Evans, CH | 2 |
| Fisher, ER | 2 |
| Shoemaker, RH | 2 |
| Sabnis, A | 1 |
| Palekar, AS | 1 |
| Oshiro, Y | 1 |
| Piper, CE | 1 |
| Balwierz, PS | 1 |
| Soelter, SG | 1 |
| Petry, TW | 1 |
| Aaron, CS | 1 |
| Ulrich, RG | 1 |
| Donarski, WJ | 1 |
| Thilagar, A | 1 |
| Kumaroo, PV | 1 |
| Doerr, CL | 1 |
| Harrington-Brock, K | 1 |
| Moore, MM | 1 |
| Sokova, OI | 2 |
| Pogosianz, HE | 1 |
| Nesnow, S | 1 |
| Garland, H | 1 |
| Curtis, G | 1 |
| Reznikoff, CA | 2 |
| Loretz, LJ | 1 |
| Christian, BJ | 2 |
| Wu, SQ | 2 |
| Meisner, LF | 2 |
| Al-Sabti, K | 1 |
| Kulagina, OE | 1 |
| Pogosiants, EE | 1 |
| Christie, NT | 1 |
| Tummolo, DM | 1 |
| Biggart, NW | 1 |
| Murphy, EC | 1 |
| Gad-El Karim, MM | 1 |
| Sadagopa Ramanujam, VM | 1 |
| Legator, MS | 2 |
| Gad-el-Karim, MM | 1 |
| Ramanujam, VM | 1 |
| Ahmed, AE | 1 |
| Mondal, S | 1 |
| Embleton, MJ | 1 |
| Marquardt, H | 1 |
| Heidelberger, C | 1 |
| Levan, G | 1 |
| Olinici, CD | 1 |
| Casto, BC | 1 |
| Vakhtin, IuB | 1 |
| Borkhsenius, TV | 1 |
| Shvemberger, IN | 1 |
| Hansteen, IL | 1 |
| Refsum, SB | 1 |
| Cioloca, L | 1 |
| Liciu, F | 1 |
| Encut, I | 1 |
| Shidou, T | 1 |
| Ingalls, TH | 1 |
| Herranen, A | 1 |
| Kaminetzky, HA | 1 |
| Jagiello, GM | 1 |
| Shick, AE | 1 |
| Christian, JC | 1 |
| Pugh, JR | 1 |
| Mellgren, J | 1 |
| Bartholdsson, E | 1 |
| Boeryd, B | 1 |
| Norrby, K | 1 |
2 reviews available for 3-methylcholanthrene and Abnormalities, Autosome
| Article | Year |
|---|---|
Is the selenium drinking water standard justified?
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adolescent; Animals; Antineoplastic Agents; Carcinogens; Chromosom | 1979 |
Mitomycin C.
Topics: Animals; Carcinogens; Chromosome Aberrations; Crosses, Genetic; Drug Evaluation, Preclinical; Female | 1976 |
44 other studies available for 3-methylcholanthrene and Abnormalities, Autosome
| Article | Year |
|---|---|
Biologically active dihydrodiol metabolites of polycyclic aromatic hydrocarbons structurally related to the potent carcinogenic hydrocarbon 7,12-dimethylbenz[a]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Chromosome Aberrations; Indicators and Reage | 1988 |
Sequential loss of cell cycle checkpoint control contributes to malignant transformation of murine embryonic fibroblasts induced by 20-methylcholanthrene.
Topics: Aneuploidy; Animals; Antimetabolites; Azacitidine; Carcinogens; Cell Cycle; Cell Cycle Proteins; Cel | 2010 |
CHROMOSOME STUDIES IN NORMAL AND LEUKEMIC RATS.
Topics: Blood Cells; Bone Marrow; Cell Biology; Chromosome Aberrations; Chromosome Disorders; Chromosomes; G | 1964 |
VULNERABILITY OF THE SUBTERMINAL CHROMOSOMES OF CULTURED RAT MAMMARY CANCER CELLS TO ALTERATIONS.
Topics: Animals; Benz(a)Anthracenes; Breast Neoplasms; Chromosome Aberrations; Chromosomes; Humans; Karyomet | 1964 |
Chromosomes of tumors induced by 3-methylcholanthrene in the golden hamster.
Topics: Animals; Bone Marrow Cells; Chromosome Aberrations; Chromosome Disorders; Chromosomes; Cricetinae; K | 1967 |
[Chromosomal study on 20-methylcholanthrene-induced tumors in the syrian hamster].
Topics: Animals; Chromosome Aberrations; Cricetinae; Cytogenetics; Female; Methylcholanthrene; Neoplasms, Ex | 1967 |
Anaphase aberrations: a measure of genotoxicity in mutagen-treated fish cells.
Topics: Aminacrine; Anaphase; Animals; Anthracenes; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Cells, Cultur | 1982 |
Effects of polycyclic hydrocarbons on the induction of chromosomal aberrations in absence of an exogenous metabolic activation system in cultured hamster cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Benzopyrenes; Cell Li | 1982 |
The effect of immunity on pulmonary metastasis of a methylcholanthrene-induced fibrosarcoma and three of its clones.
Topics: Animals; Antigens, Neoplasm; Chromosome Aberrations; Clone Cells; Fibrosarcoma; Lung Neoplasms; Meth | 1984 |
Chromosome alteration and the development of tumors. XXIII. Banding karyotype analyses of methylcholanthrene-induced tumors in the Indian spiny mouse, Mus platythrix, with special regard to the anomalies of chromosomes with nucleolar organizer regions.
Topics: Animals; Chromosome Aberrations; Chromosome Banding; Karyotyping; Methylcholanthrene; Mice; Neoplasm | 1981 |
Aneuploidy induction by benzo[a]pyrene and polyploidy induction by 7,12-dimethylbenz[a]anthracene in Chinese hamster cell lines V79-MZ and V79.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aneuploidy; Animals; Benzo(a)pyrene; Cell Cycle; Cell Line; CHO Ce | 1997 |
Centromeric asymmetry and induction of translocations and sister chromatid exchanges in mouse chromosomes.
Topics: Animals; Bromodeoxyuridine; Cell Line; Chromatids; Chromosome Aberrations; Chromosomes; Crossing Ove | 1975 |
Are methylcholanthrene-induced sarcoma-associated, rejection-inducing (TSTA) antigens, modified forms of H-2 or linked determinants?
Topics: Animals; Antigens, Neoplasm; Cell Line; Chromosome Aberrations; Epitopes; Genetic Linkage; Genetic V | 1975 |
Sister chromatid exchange and chromosome aberration analysis with the use of several carcinogens and noncarcinogens.
Topics: 2-Acetylaminofluorene; 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Acridines; Benzop | 1977 |
Chromosomal effects of carcinogens and non-carcinogens on WI-38 after short term exposures with and without metabolic activation.
Topics: 4-Nitroquinoline-1-oxide; Benzopyrenes; Caffeine; Cell Line; Chromosome Aberrations; Chromosomes; Di | 1977 |
Specific chromosome changes in malignancy: studies in rat sarcomas induced by two polycyclic hydrocarbons.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Benzopyrenes; Cell Division; Chromoso | 1975 |
Biologic analysis of fetal MRC rat lung epithelial cells treated with 3-methylcholanthrene in culture: premalignant and malignant stages.
Topics: Animals; Animals, Newborn; Carcinoma, Squamous Cell; Cell Survival; Cell Transformation, Neoplastic; | 1977 |
Cytological effect of nogalamycin in mammals and regression of methylcholanthrene-induced and spontaneous tumors in rats.
Topics: Animals; Chromosome Aberrations; Female; Fibrosarcoma; Humans; Male; Methylcholanthrene; Mice; Mice, | 1976 |
Neoplastic transformation of guinea pig fetal cells in culture induced by chemical carcinogens.
Topics: Acetone; Aflatoxins; Amides; Animals; Benz(a)Anthracenes; Carcinogens; Cell Division; Cell Transform | 1975 |
Relationship of hyperplasia to cancer in 3-methylcholanthrene-induced mammary tumorogenesis.
Topics: Animals; Biopsy; Breast; Cell Nucleolus; Chromatin; Chromosome Aberrations; Disease Models, Animal; | 1975 |
Identification of premalignant hyperplasia in methylcholanthrene-induced mammary tumorogenesis.
Topics: Aneuploidy; Animals; Chromosome Aberrations; Estradiol; Female; Hyperplasia; Mammary Glands, Animal; | 1975 |
Chromosome patterns (G and C bands) of in vitro chemical carcinogen-transformed guinea pig cells.
Topics: Benzopyrenes; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Chromosome Aberrations; | 1976 |
Chinese hamster ovary cell assays for mutation and chromosome damage: data from non-carcinogens.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenicity Tests; Cell Survival; CHO Cells; Chromoso | 1991 |
Comparative mutagenicity testing of bropirimine, 2. Further characterization and mechanistic investigation of clastogenesis.
Topics: Animals; Antineoplastic Agents; Biotransformation; Cell Line; Chromosome Aberrations; Cricetinae; Cr | 1991 |
Micronucleus, chromosome aberration, and small-colony TK mutant analysis to quantitate chromosomal damage in L5178Y mouse lymphoma cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aminoacridines; Amsacrine; Animals; Bleomycin; Chromosome Aberrati | 1989 |
Non-random karyotypic changes in Djungarian hamster tumors induced by 3-methylcholanthrene.
Topics: Adenocarcinoma; Animals; Chromosome Aberrations; Cricetinae; Female; Fibroma; Fibrosarcoma; Karyotyp | 1989 |
Inhibition of morphological transformation of C3H10T1/2CL8 mouse embryo cells by multiple carcinogen treatments.
Topics: Animals; Benzo(a)pyrene; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Chromosome Aberrat | 1989 |
Neoplastic transformation of SV40-immortalized human urinary tract epithelial cells by in vitro exposure to 3-methylcholanthrene.
Topics: Animals; Cell Transformation, Neoplastic; Chromosome Aberrations; Female; Humans; Methylcholanthrene | 1988 |
Marker chromosome stability associated with neoplastic transformation of human uroepithelial cells.
Topics: Animals; Carcinoma, Transitional Cell; Cell Transformation, Neoplastic; Cell Transformation, Viral; | 1988 |
Carcinogenic-mutagenic chemicals induced chromosomal aberrations in the kidney cells of three cyprinids.
Topics: Aflatoxin B1; Aflatoxins; Animals; Aroclors; Benzidines; Benzo(a)pyrene; Carcinogens; Chlorodiphenyl | 1985 |
[Nonrandom karyotype changes in chemically induced tumors of the Djungarian hamster].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Chromosome Aberrations; Cricetinae; Female; Genetic Marke | 1988 |
Chromosomal changes in cell lines from mouse tumors induced by nickel sulfide and methylcholanthrene.
Topics: Aneuploidy; Animals; Blotting, Northern; Blotting, Southern; Carcinogenicity Tests; Chromosome Aberr | 1988 |
Correlation between the induction of micronuclei in bone marrow by benzene exposure and the excretion of metabolites in urine of CD-1 mice.
Topics: Animals; Benzene; Benzoflavones; beta-Naphthoflavone; Biotransformation; Bone Marrow; Catechols; Cel | 1986 |
Benzene myeloclastogenicity: a function of its metabolism.
Topics: Animals; Benzene; Benzoflavones; beta-Naphthoflavone; Bone Marrow; Catechols; Chromosome Aberrations | 1985 |
Production of variants of decreased malignancy and antigenicity from clones transformed in vitro by methylcholanthrene.
Topics: Animals; Antigens; Antigens, Neoplasm; Ascitic Fluid; Cell Line; Chromosome Aberrations; Clone Cells | 1971 |
Nomenclature for G-bands in rat chromosomes.
Topics: Animals; Benz(a)Anthracenes; Cells, Cultured; Chromosome Aberrations; Chromosomes; Fibroblasts; Kary | 1974 |
Random chromosome changes following SA7 transformation of Syrian hamster cells.
Topics: Adenoviridae; Aneuploidy; Animals; Animals, Newborn; Benz(a)Anthracenes; Cell Transformation, Neopla | 1974 |
[Variation and selection in clone populations of murine rhabdomyosarcoma in vivo. I. Frequency of genomic mutations].
Topics: Aneuploidy; Animals; Cell Nucleus; Chromosome Aberrations; Clone Cells; DNA, Neoplasm; Methylcholant | 1972 |
Chromosomal changes in 20-methylcholanthrene induced sarcomas in mice in relation to time of appearance of the tumours.
Topics: Animals; Cell Division; Chromosome Aberrations; Female; Injections, Subcutaneous; Karyotyping; Methy | 1969 |
Chromosomal analysis of some transplanted tumors induced by 3-methylcholanthrene in golden hamsters.
Topics: Animals; Chromosome Aberrations; Cricetinae; Diploidy; Karyotyping; Methylcholanthrene; Neoplasm Tra | 1969 |
Cytogenetic analysis of multinucleate ascitic tumor in golden hamsters.
Topics: Animals; Ascitic Fluid; Chromosome Aberrations; Chromosome Mapping; Cricetinae; Karyotyping; Methylc | 1971 |
Differential chromosomal effects of carcinogenic and noncarcinogenic substances. An experimental study on the mouse.
Topics: Animals; Carcinoma; Cervix Uteri; Chromosome Aberrations; Chromosomes; Female; Methylcholanthrene; M | 1967 |
Karyotypes of rats from strains of different susceptibility to mammary cancer induction.
Topics: Animals; Breeding; Chromosome Aberrations; Female; Karyotyping; Mammary Neoplasms, Experimental; Met | 1968 |
A spontaneously metastasizing 20-methylcholanthrene-induced rhabdomyosarcoma and its transformation to ascites form in the CBA mouse.
Topics: Animals; Carcinogens; Chromosome Aberrations; Chromosome Disorders; Female; Injections, Intraperiton | 1966 |