3-methyl-4-nitroquinoline 1-oxide has been researched along with Ataxia Telangiectasia in 1 studies
*Ataxia Telangiectasia: An autosomal recessive inherited disorder characterized by choreoathetosis beginning in childhood, progressive CEREBELLAR ATAXIA; TELANGIECTASIS of CONJUNCTIVA and SKIN; DYSARTHRIA; B- and T-cell immunodeficiency, and RADIOSENSITIVITY to IONIZING RADIATION. Affected individuals are prone to recurrent sinobronchopulmonary infections, lymphoreticular neoplasms, and other malignancies. Serum ALPHA-FETOPROTEINS are usually elevated. (Menkes, Textbook of Child Neurology, 5th ed, p688) The gene for this disorder (ATM) encodes a cell cycle checkpoint protein kinase and has been mapped to chromosome 11 (11q22-q23). [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mirzayans, R; Paterson, MC; Smith, BP | 1 |
1 other study(ies) available for 3-methyl-4-nitroquinoline 1-oxide and Ataxia Telangiectasia
| Article | Year |
|---|---|
Hypersensitivity to cell killing and faulty repair of 1-beta-D-arabinofuranosylcytosine-detectable sites in human (ataxia-telangiectasia) fibroblasts treated with 4-nitroquinoline 1-oxide.
Topics: 4-Nitroquinoline-1-oxide; Ataxia Telangiectasia; Cell Survival; Cytarabine; DNA; DNA Damage; DNA Repair; Genetic Complementation Test; Humans; In Vitro Techniques; Nitroquinolines | 1989 |