Page last updated: 2024-10-21

3-methoxytyramine and Pheochromocytoma

3-methoxytyramine has been researched along with Pheochromocytoma in 35 studies

3-methoxytyramine: RN given refers to parent cpd
3-methoxytyramine : A monomethoxybenzene that is dopamine in which the hydroxy group at position 3 is replaced by a methoxy group. It is a metabolite of the neurotransmitter dopamine and considered a potential biomarker of pheochromocytomas and paragangliomas.

Pheochromocytoma: A usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the ADRENAL MEDULLA or sympathetic paraganglia. The cardinal symptom, reflecting the increased secretion of EPINEPHRINE and NOREPINEPHRINE, is HYPERTENSION, which may be persistent or intermittent. During severe attacks, there may be HEADACHE; SWEATING, palpitation, apprehension, TREMOR; PALLOR or FLUSHING of the face, NAUSEA and VOMITING, pain in the CHEST and ABDOMEN, and paresthesias of the extremities. The incidence of malignancy is as low as 5% but the pathologic distinction between benign and malignant pheochromocytomas is not clear. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1298)

Research Excerpts

ExcerptRelevanceReference
"Measurements of plasma free metanephrines (MNs), including MN and normetanephrine, provide high sensitivity and specificity for the diagnosis of pheochromocytoma and paraganglioma (PPGL)."8.12Addition of 3-methoxytyramine or chromogranin A to plasma free metanephrines as the initial test for pheochromocytoma and paraganglioma: Which is the best diagnostic strategy. ( Gao, Y; Guo, X; Li, X; Li, Y; Liu, L; Song, Z; Wang, T; Xie, W; Zhang, J, 2022)
"Accurate diagnosis of pheochromocytoma and paraganglioma (PPGLs) is highly dependent on the detection of metanephrines and catecholamines."8.02Study of stability and interference for catecholamines and metanephrines, 3-methoxytyramine: key point of an accurate diagnosis for pheochromocytoma and paraganglioma. ( Cong, H; Gao, X; Guo, Y; Shi, X; Sun, N; Wang, K; Xie, L; Zhang, W; Zhou, Z, 2021)
" This study assessed whether urinary-free normetanephrine, metanephrine and methoxytyramine in overnight/first-morning urine collections might offer an alternative to measurements in 24-h collections or plasma for diagnosis of pheochromocytoma and paraganglioma (PPGL)."7.96Overnight/first-morning urine free metanephrines and methoxytyramine for diagnosis of pheochromocytoma and paraganglioma: is this an option? ( Bursztyn, M; Conrad, C; Constantinescu, G; Därr, R; Eisenhofer, G; Fliedner, S; Kaden, D; Langton, K; Lenders, JWM; Pamporaki, C; Peitzsch, M; Prejbisz, A; Sinnott, RO, 2020)
"The 24 h urinary-fractionated metanephrine (MN) and normetanephrine (NMN) are recommended as the preferred indicators for laboratory diagnosis of pheochromocytoma and paraganglioma (PPGL)."7.96Stability and reference intervals of spot urinary fractionated metanephrines and methoxytyramine by tandem mass spectrometry as a screening method for pheochromocytoma and paraganglioma. ( Cong, H; Dai, S; Gao, X; Shi, X; Wang, K; Zhang, W; Zhou, Z, 2020)
"In patients with phaeochromocytomas or paragangliomas (PPGLs), 24-h urine collections for metanephrines (uMNs) are cumbersome."7.96Random 'spot' urinary metanephrines compared with 24-h-urinary and plasma results in phaeochromocytomas and paragangliomas. ( Grossman, AB; Isidori, AM; Jafar-Mohammadi, B; James, T; Maunsell, Z; May, CJH; Sbardella, E; Shine, B; Tadman, M, 2020)
"Detection of normetanephrine (NMN), metanephrine (MN) and 3-methoxytyramine (3-MT) could be used to diagnose pheochromocytomas and paragangliomas (PPGLs)."7.96Detection of spot urinary free metanephrines and 3-methoxytyramine with internal reference correction for the diagnosis of pheochromocytomas and paragangliomas. ( Chen, H; Ding, M; Luo, C; Wang, H; Zhang, X; Zhen, Q; Zou, W, 2020)
"Plasma free metanephrines are commonly used for diagnosis of pheochromocytoma and paraganglioma (PPGLs), but can also provide other information."7.96Plasma metanephrines and prospective prediction of tumor location, size and mutation type in patients with pheochromocytoma and paraganglioma. ( Bechmann, N; Beuschlein, F; Calsina, B; Constantinescu, G; Deutschbein, T; Eisenhofer, G; Fankhauser, M; Fassnacht, M; Fliedner, S; Langton, K; Lenders, JWM; Monteagudo, M; Nölting, S; Pamporaki, C; Peitzsch, M; Prejbisz, A; Robledo, M; Stell, A; Timmers, HJLM, 2020)
"Measurements of plasma methoxytyramine, the O-methylated dopamine metabolite, are useful for detecting rare dopamine-producing pheochromocytomas and paragangliomas (PPGLs) and head and neck paragangliomas (HNPGLs), but utility for screening beyond that achieved using standard measurements of normetanephrine and metanephrine is unclear."7.85Plasma methoxytyramine: clinical utility with metanephrines for diagnosis of pheochromocytoma and paraganglioma. ( Beuschlein, F; Brugger, C; Eisenhofer, G; Fassnacht, M; Fliedner, S; Gudziol, V; Hanus, K; Januszewicz, A; Langton, K; Lenders, JWM; Pamporaki, C; Peitzsch, M; Prejbisz, A; Rao, D; Stell, A; Timmers, HJLM, 2017)
"This work discusses the clinical performance of deconjugated metanephrine (MN), normetanephrine (NMN) and 3-methoxytyramine (3MT) determined in the basal first morning urine using a chromatographic method with electrochemical detection for the clinical diagnosis of pheochromocytoma (PHEO) and paraganglioma (PGL)."7.81Deconjugated urinary metanephrine, normetanephrine and 3-methoxytyramine in laboratory diagnosis of pheochromocytoma and paraganglioma. ( Bešťák, J; Bílek, R; Dušková, J; Michalský, D; Novák, K; Vlček, P; Widimský, J; Zelinka, T, 2015)
"The effects of an organophosphate (OP) pesticide, fenthion (FEN), on the release and metabolism of dopamine were evaluated in a clonal line of rat pheochromocytoma (PC12) cells."7.67Release and metabolism of dopamine in a clonal line of pheochromocytoma (PC12) cells exposed to fenthion. ( Bowen, JM; Hazen, AA; Tuler, SM, 1989)
"Pheochromocytomas are rare catecholamine-producing tumors derived in more than 30% of cases from mutations in 9 tumor-susceptibility genes identified to date, including von Hippel-Lindau tumor suppressor (VHL); succinate dehydrogenase complex, subunit B, iron sulfur (Ip) (SDHB); and succinate dehydrogenase complex, subunit D, integral membrane protein (SDHD)."5.37Measurements of plasma methoxytyramine, normetanephrine, and metanephrine as discriminators of different hereditary forms of pheochromocytoma. ( Adams, K; Bornstein, SR; Bratslavsky, G; Eisenhofer, G; Grebe, SK; Hofbauer, LC; Lenders, JW; Linehan, WM; Mannelli, M; Pacak, K; Tiebel, O; Timmers, H, 2011)
"Measurements of plasma metanephrines and methoxytyramine provide a sensitive test for diagnosis of pheochromocytoma/paraganglioma."4.84False-positive results for pheochromocytoma associated with norepinephrine reuptake blockade. ( Biemann, R; Eisenhofer, G; Pamporaki, C; Peitzsch, M; Rayes, N; Rohm, S; Sabri, O; Sandner, B; Schürfeld, R; Tönjes, A, 2024)
"Measurements of plasma free metanephrines (MNs), including MN and normetanephrine, provide high sensitivity and specificity for the diagnosis of pheochromocytoma and paraganglioma (PPGL)."4.12Addition of 3-methoxytyramine or chromogranin A to plasma free metanephrines as the initial test for pheochromocytoma and paraganglioma: Which is the best diagnostic strategy. ( Gao, Y; Guo, X; Li, X; Li, Y; Liu, L; Song, Z; Wang, T; Xie, W; Zhang, J, 2022)
"Accurate diagnosis of pheochromocytoma and paraganglioma (PPGLs) is highly dependent on the detection of metanephrines and catecholamines."4.02Study of stability and interference for catecholamines and metanephrines, 3-methoxytyramine: key point of an accurate diagnosis for pheochromocytoma and paraganglioma. ( Cong, H; Gao, X; Guo, Y; Shi, X; Sun, N; Wang, K; Xie, L; Zhang, W; Zhou, Z, 2021)
" This study assessed whether urinary-free normetanephrine, metanephrine and methoxytyramine in overnight/first-morning urine collections might offer an alternative to measurements in 24-h collections or plasma for diagnosis of pheochromocytoma and paraganglioma (PPGL)."3.96Overnight/first-morning urine free metanephrines and methoxytyramine for diagnosis of pheochromocytoma and paraganglioma: is this an option? ( Bursztyn, M; Conrad, C; Constantinescu, G; Därr, R; Eisenhofer, G; Fliedner, S; Kaden, D; Langton, K; Lenders, JWM; Pamporaki, C; Peitzsch, M; Prejbisz, A; Sinnott, RO, 2020)
"The 24 h urinary-fractionated metanephrine (MN) and normetanephrine (NMN) are recommended as the preferred indicators for laboratory diagnosis of pheochromocytoma and paraganglioma (PPGL)."3.96Stability and reference intervals of spot urinary fractionated metanephrines and methoxytyramine by tandem mass spectrometry as a screening method for pheochromocytoma and paraganglioma. ( Cong, H; Dai, S; Gao, X; Shi, X; Wang, K; Zhang, W; Zhou, Z, 2020)
"In patients with phaeochromocytomas or paragangliomas (PPGLs), 24-h urine collections for metanephrines (uMNs) are cumbersome."3.96Random 'spot' urinary metanephrines compared with 24-h-urinary and plasma results in phaeochromocytomas and paragangliomas. ( Grossman, AB; Isidori, AM; Jafar-Mohammadi, B; James, T; Maunsell, Z; May, CJH; Sbardella, E; Shine, B; Tadman, M, 2020)
"Detection of normetanephrine (NMN), metanephrine (MN) and 3-methoxytyramine (3-MT) could be used to diagnose pheochromocytomas and paragangliomas (PPGLs)."3.96Detection of spot urinary free metanephrines and 3-methoxytyramine with internal reference correction for the diagnosis of pheochromocytomas and paragangliomas. ( Chen, H; Ding, M; Luo, C; Wang, H; Zhang, X; Zhen, Q; Zou, W, 2020)
"Plasma free metanephrines are commonly used for diagnosis of pheochromocytoma and paraganglioma (PPGLs), but can also provide other information."3.96Plasma metanephrines and prospective prediction of tumor location, size and mutation type in patients with pheochromocytoma and paraganglioma. ( Bechmann, N; Beuschlein, F; Calsina, B; Constantinescu, G; Deutschbein, T; Eisenhofer, G; Fankhauser, M; Fassnacht, M; Fliedner, S; Langton, K; Lenders, JWM; Monteagudo, M; Nölting, S; Pamporaki, C; Peitzsch, M; Prejbisz, A; Robledo, M; Stell, A; Timmers, HJLM, 2020)
"Measurements of plasma methoxytyramine, the O-methylated dopamine metabolite, are useful for detecting rare dopamine-producing pheochromocytomas and paragangliomas (PPGLs) and head and neck paragangliomas (HNPGLs), but utility for screening beyond that achieved using standard measurements of normetanephrine and metanephrine is unclear."3.85Plasma methoxytyramine: clinical utility with metanephrines for diagnosis of pheochromocytoma and paraganglioma. ( Beuschlein, F; Brugger, C; Eisenhofer, G; Fassnacht, M; Fliedner, S; Gudziol, V; Hanus, K; Januszewicz, A; Langton, K; Lenders, JWM; Pamporaki, C; Peitzsch, M; Prejbisz, A; Rao, D; Stell, A; Timmers, HJLM, 2017)
"This work discusses the clinical performance of deconjugated metanephrine (MN), normetanephrine (NMN) and 3-methoxytyramine (3MT) determined in the basal first morning urine using a chromatographic method with electrochemical detection for the clinical diagnosis of pheochromocytoma (PHEO) and paraganglioma (PGL)."3.81Deconjugated urinary metanephrine, normetanephrine and 3-methoxytyramine in laboratory diagnosis of pheochromocytoma and paraganglioma. ( Bešťák, J; Bílek, R; Dušková, J; Michalský, D; Novák, K; Vlček, P; Widimský, J; Zelinka, T, 2015)
"Measurements of plasma normetanephrine (NMN) and metanephrine (MN) provide a sensitive test for diagnosis of phaeochromocytomas and paragangliomas (PPGLs), but do not allow detection of dopamine-producing tumours."3.79Analysis of plasma 3-methoxytyramine, normetanephrine and metanephrine by ultraperformance liquid chromatography-tandem mass spectrometry: utility for diagnosis of dopamine-producing metastatic phaeochromocytoma. ( Arlt, W; Beuschlein, F; Eisenhofer, G; Januszewicz, A; Kroiß, M; Peitzsch, M; Prejbisz, A; Siegert, G, 2013)
"Measurements of the 3-O-methylated metabolites of catecholamines [metanephrines (MNs)] in plasma or urine are recommended for diagnosis of pheochromocytoma."3.75Dietary influences on plasma and urinary metanephrines: implications for diagnosis of catecholamine-producing tumors. ( de Jong, WH; de Vries, EG; Eisenhofer, G; Kema, IP; Muskiet, FA; Post, WJ, 2009)
"The effects of an organophosphate (OP) pesticide, fenthion (FEN), on the release and metabolism of dopamine were evaluated in a clonal line of rat pheochromocytoma (PC12) cells."3.67Release and metabolism of dopamine in a clonal line of pheochromocytoma (PC12) cells exposed to fenthion. ( Bowen, JM; Hazen, AA; Tuler, SM, 1989)
"Pheochromocytoma is a rare neuroendocrine tumor, clinically characterized by high blood pressure, palpitations, and headache."1.51Electrical Remodeling of Ventricular Repolarization Abnormality after Treatment in Pheochromocytoma: U Wave Finding in a Retrospective Analysis. ( De Luca, G; Di Stolfo, G; Maggio, A; Mastroianno, S; Potenza, DR; Russo, A; Salvatori, MP, 2019)
"Pheochromocytomas are rare catecholamine-producing tumors derived in more than 30% of cases from mutations in 9 tumor-susceptibility genes identified to date, including von Hippel-Lindau tumor suppressor (VHL); succinate dehydrogenase complex, subunit B, iron sulfur (Ip) (SDHB); and succinate dehydrogenase complex, subunit D, integral membrane protein (SDHD)."1.37Measurements of plasma methoxytyramine, normetanephrine, and metanephrine as discriminators of different hereditary forms of pheochromocytoma. ( Adams, K; Bornstein, SR; Bratslavsky, G; Eisenhofer, G; Grebe, SK; Hofbauer, LC; Lenders, JW; Linehan, WM; Mannelli, M; Pacak, K; Tiebel, O; Timmers, H, 2011)

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-19903 (8.57)18.7374
1990's1 (2.86)18.2507
2000's4 (11.43)29.6817
2010's15 (42.86)24.3611
2020's12 (34.29)2.80

Authors

AuthorsStudies
Liu, L1
Xie, W1
Song, Z1
Wang, T1
Li, X1
Gao, Y1
Li, Y1
Zhang, J1
Guo, X2
Wang, K3
Gao, X2
Zhang, W2
Sun, N1
Xie, L1
Cong, H2
Guo, Y1
Shi, X2
Zhou, Z2
Yu, S1
Zhou, W1
Yu, J1
Li, M1
Zhang, S1
Jiang, X1
Wang, H2
Ma, X1
Zou, Y1
Wang, D1
Cheng, Q1
Xie, S1
Luo, W1
Qiu, L1
Pamporaki, C7
Berends, AMA1
Filippatos, A1
Prodanov, T1
Meuter, L1
Prejbisz, A8
Beuschlein, F6
Fassnacht, M4
Timmers, HJLM3
Nölting, S2
Abhyankar, K1
Constantinescu, G3
Kunath, C2
de Haas, RJ1
Remde, H1
Bornstein, SR5
Januszewicz, A6
Robledo, M2
Lenders, JWM5
Kerstens, MN2
Pacak, K4
Eisenhofer, G15
Schürfeld, R1
Peitzsch, M10
Rayes, N1
Sabri, O1
Rohm, S1
Biemann, R1
Sandner, B1
Tönjes, A1
Kaden, D1
Langton, K3
Conrad, C1
Fliedner, S3
Sinnott, RO1
Därr, R2
Bursztyn, M1
Dai, S1
Sbardella, E1
Maunsell, Z1
May, CJH1
Tadman, M1
James, T1
Jafar-Mohammadi, B1
Isidori, AM1
Grossman, AB1
Shine, B1
Zhang, X1
Zhen, Q1
Zou, W1
Chen, H1
Luo, C1
Ding, M1
Deutschbein, T1
Calsina, B1
Monteagudo, M1
Bechmann, N1
Fankhauser, M1
Stell, A3
Jian, M1
Huang, H1
Li, K1
Chuan, L1
Li, L1
Jiang, L1
Małecki, R1
Pistrosch, F1
Bishoff, S1
Mueller, P1
Meyer, I1
Reimann, D1
Hanus, K2
Parmentier, S1
Passauer, J1
Rao, D1
Brugger, C1
Gudziol, V1
Mangelis, A1
Huebner, A1
Chtioui, H1
Sadowski, SM1
Winzeler, B1
Tschopp, O1
Grouzmann, E1
Abid, K1
Di Stolfo, G1
Mastroianno, S1
Maggio, A1
De Luca, G1
Potenza, DR1
Salvatori, MP1
Russo, A1
Kroiß, M1
Arlt, W1
Siegert, G3
Brown, S1
Pelzel, D1
Lattke, P1
Glöckner, S1
Reichmann, H1
Miehle, K1
Peczkowska, M1
Weismann, D1
Sinnott, R1
Neumann, HP1
Lenders, J1
van Berkel, A1
Lenders, JW3
Timmers, HJ2
Garcia Hejl, C1
Dedome, E1
Chianea, D1
Ramirez Martinez, J1
Vest, P1
Osinga, TE1
Korpershoek, E1
de Krijger, RR1
Dullaart, RP1
Kema, IP3
van der Laan, BF1
van der Horst-Schrivers, AN1
Links, TP1
Bílek, R1
Zelinka, T1
Vlček, P1
Dušková, J1
Michalský, D1
Novák, K1
Bešťák, J1
Widimský, J1
Patin, F1
Crinière, L1
Francia, T1
Kassem, S1
Pierre, P1
Bruno, C1
Vayne, C1
Vourc'h, P1
Benz-de Bretagne, I1
Andres, CR1
Blasco, H1
de Jong, WH1
Post, WJ1
Muskiet, FA1
de Vries, EG1
Timmers, H1
Mannelli, M2
Grebe, SK1
Hofbauer, LC1
Tiebel, O1
Adams, K2
Bratslavsky, G1
Linehan, WM2
Friberg, P1
Milosevic, D1
Serra, PA1
Rocchitta, G1
Delogu, MR1
Migheli, R1
Taras, MG1
Mura, MP1
Esposito, G1
Miele, E1
Desole, MS1
Miele, M1
Goldstein, DS1
Sullivan, P1
Csako, G1
Brouwers, FM1
Lai, EW1
Adams, KT1
Buu, NT1
Angers, M1
Chevalier, D1
Kuchel, O1
Jouve, J1
Mariotte, N1
Sureau, C1
Muh, JP1
Proye, C1
Racadot-Leroy, N1
Vix, M1
Vermesse, B1
Carnaille, B1
Willemsen, JJ1
Ross, HA1
Wolthers, BG1
Sweep, CG1
Tuler, SM1
Hazen, AA1
Bowen, JM1

Reviews

2 reviews available for 3-methoxytyramine and Pheochromocytoma

ArticleYear
Diagnosis of endocrine disease: Biochemical diagnosis of phaeochromocytoma and paraganglioma.
    European journal of endocrinology, 2014, Volume: 170, Issue:3

    Topics: Adrenal Gland Neoplasms; Adult; Biomarkers, Tumor; Catecholamines; Dopamine; False Negative Reaction

2014
Laboratory evaluation of pheochromocytoma and paraganglioma.
    Clinical chemistry, 2014, Volume: 60, Issue:12

    Topics: Adrenal Gland Neoplasms; Clinical Laboratory Techniques; Dopamine; Humans; Metanephrine; Normetaneph

2014

Trials

2 trials available for 3-methoxytyramine and Pheochromocytoma

ArticleYear
Optimized procedures for testing plasma metanephrines in patients on hemodialysis.
    Scientific reports, 2021, 07-19, Volume: 11, Issue:1

    Topics: Adrenal Gland Neoplasms; Aged; Aged, 80 and over; Blood Chemical Analysis; Blood Specimen Collection

2021
Biochemical diagnosis of phaeochromocytoma using plasma-free normetanephrine, metanephrine and methoxytyramine: importance of supine sampling under fasting conditions.
    Clinical endocrinology, 2014, Volume: 80, Issue:4

    Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Blood Specim

2014

Other Studies

31 other studies available for 3-methoxytyramine and Pheochromocytoma

ArticleYear
Addition of 3-methoxytyramine or chromogranin A to plasma free metanephrines as the initial test for pheochromocytoma and paraganglioma: Which is the best diagnostic strategy.
    Clinical endocrinology, 2022, Volume: 96, Issue:2

    Topics: Adrenal Gland Neoplasms; Chromogranin A; Dopamine; Humans; Metanephrine; Paraganglioma; Pheochromocy

2022
Study of stability and interference for catecholamines and metanephrines, 3-methoxytyramine: key point of an accurate diagnosis for pheochromocytoma and paraganglioma.
    Scandinavian journal of clinical and laboratory investigation, 2021, Volume: 81, Issue:7

    Topics: Adrenal Gland Neoplasms; Anticoagulants; Catecholamines; Dopamine; Epinephrine; Hemoglobins; Humans;

2021
An automated magnetic bead extraction method for measuring plasma metanephrines and 3-methoxytyramine using liquid chromatography tandem mass spectrometry.
    Analytical and bioanalytical chemistry, 2022, Volume: 414, Issue:11

    Topics: Adrenal Gland Neoplasms; Chromatography, High Pressure Liquid; Chromatography, Liquid; Dopamine; Hum

2022
Prediction of metastatic pheochromocytoma and paraganglioma: a machine learning modelling study using data from a cross-sectional cohort.
    The Lancet. Digital health, 2023, Volume: 5, Issue:9

    Topics: Adrenal Gland Neoplasms; Cross-Sectional Studies; Humans; Machine Learning; Paraganglioma; Pheochrom

2023
False-positive results for pheochromocytoma associated with norepinephrine reuptake blockade.
    Endocrine-related cancer, 2024, Jan-01, Volume: 31, Issue:1

    Topics: Adrenal Gland Neoplasms; Antidepressive Agents, Tricyclic; Humans; Metanephrine; Norepinephrine; Nor

2024
Overnight/first-morning urine free metanephrines and methoxytyramine for diagnosis of pheochromocytoma and paraganglioma: is this an option?
    European journal of endocrinology, 2020, Volume: 182, Issue:5

    Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Aged; Aged, 80 and over; Biomarkers; Dopamine; Female; H

2020
Stability and reference intervals of spot urinary fractionated metanephrines and methoxytyramine by tandem mass spectrometry as a screening method for pheochromocytoma and paraganglioma.
    Endocrine, 2020, Volume: 69, Issue:1

    Topics: Adrenal Gland Neoplasms; Chromatography, Liquid; Dopamine; Female; Humans; Male; Metanephrine; Norme

2020
Random 'spot' urinary metanephrines compared with 24-h-urinary and plasma results in phaeochromocytomas and paragangliomas.
    European journal of endocrinology, 2020, Volume: 183, Issue:2

    Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Age Factors; Aged; Aged, 80 and over; Area Under Curve;

2020
Detection of spot urinary free metanephrines and 3-methoxytyramine with internal reference correction for the diagnosis of pheochromocytomas and paragangliomas.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2020, Nov-01, Volume: 1156

    Topics: Adrenal Gland Neoplasms; Chromatography, High Pressure Liquid; Cohort Studies; Dopamine; Humans; Lim

2020
Plasma metanephrines and prospective prediction of tumor location, size and mutation type in patients with pheochromocytoma and paraganglioma.
    Clinical chemistry and laboratory medicine, 2020, 10-01, Volume: 59, Issue:2

    Topics: Adrenal Gland Neoplasms; Adult; Aged; Aged, 80 and over; Algorithms; Biomarkers, Tumor; Dopamine; Fe

2020
A 3-min UPLC-MS/MS method for the simultaneous determination of plasma catecholamines and their metabolites: Method verification and diagnostic efficiency.
    Clinical biochemistry, 2021, Volume: 87

    Topics: Adrenal Gland Neoplasms; Calibration; Catecholamines; Chromatography, Liquid; Dopamine; Female; Huma

2021
Plasma methoxytyramine: clinical utility with metanephrines for diagnosis of pheochromocytoma and paraganglioma.
    European journal of endocrinology, 2017, Volume: 177, Issue:2

    Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Aged; Aged, 80 and over; Biomarkers; Child; Dopamine; Fe

2017
Age-specific pediatric reference intervals for plasma free normetanephrine, metanephrine, 3-methoxytyramine and 3-O-methyldopa: Particular importance for early infancy.
    Clinica chimica acta; international journal of clinical chemistry, 2019, Volume: 494

    Topics: Adolescent; Adrenal Gland Neoplasms; Aging; Blood Chemical Analysis; Catecholamines; Child; Child, P

2019
High concentration of plasma methoxytyramine: dopamine-producing tumour or Parkinson's disease therapy?
    Annals of clinical biochemistry, 2019, Volume: 56, Issue:4

    Topics: Adrenal Gland Neoplasms; Aged; Aged, 80 and over; Biomarkers, Tumor; Cohort Studies; Dopamine; Dopam

2019
Electrical Remodeling of Ventricular Repolarization Abnormality after Treatment in Pheochromocytoma: U Wave Finding in a Retrospective Analysis.
    BioMed research international, 2019, Volume: 2019

    Topics: Adrenal Gland Neoplasms; Adult; Dopamine; Electrocardiography; Female; Heart Diseases; Humans; Male;

2019
Analysis of plasma 3-methoxytyramine, normetanephrine and metanephrine by ultraperformance liquid chromatography-tandem mass spectrometry: utility for diagnosis of dopamine-producing metastatic phaeochromocytoma.
    Annals of clinical biochemistry, 2013, Volume: 50, Issue:Pt 2

    Topics: Adrenal Gland Neoplasms; Adult; Aged; Blood Chemical Analysis; Chromatography, High Pressure Liquid;

2013
Levodopa therapy in Parkinson's disease: influence on liquid chromatographic tandem mass spectrometric-based measurements of plasma and urinary normetanephrine, metanephrine and methoxytyramine.
    Annals of clinical biochemistry, 2014, Volume: 51, Issue:Pt 1

    Topics: Aged; Aged, 80 and over; Chromatography, Liquid; Dopamine; Epinephrine; Female; Humans; Levodopa; Ma

2014
Pheochromocytoma: yes or no?
    Clinical chemistry, 2014, Volume: 60, Issue:3

    Topics: Adrenal Gland Neoplasms; Aged; Diagnosis, Differential; Dopamine; Female; Humans; Pheochromocytoma

2014
Catecholamine-Synthesizing Enzymes Are Expressed in Parasympathetic Head and Neck Paraganglioma Tissue.
    Neuroendocrinology, 2015, Volume: 101, Issue:4

    Topics: Aromatic-L-Amino-Acid Decarboxylases; Dopamine; Dopamine beta-Hydroxylase; Female; Head and Neck Neo

2015
Deconjugated urinary metanephrine, normetanephrine and 3-methoxytyramine in laboratory diagnosis of pheochromocytoma and paraganglioma.
    Physiological research, 2015, Volume: 64, Issue:Suppl 2

    Topics: Adrenal Gland Neoplasms; Adult; Aged; Biomarkers; Chromatography, High Pressure Liquid; Clinical Lab

2015
Low specificity of urinary 3-methoxytyramine in screening of dopamine-secreting pheochromocytomas and paragangliomas.
    Clinical biochemistry, 2016, Volume: 49, Issue:15

    Topics: Adrenal Gland Neoplasms; Dopamine; Humans; Paraganglioma; Pheochromocytoma; Retrospective Studies

2016
Dietary influences on plasma and urinary metanephrines: implications for diagnosis of catecholamine-producing tumors.
    The Journal of clinical endocrinology and metabolism, 2009, Volume: 94, Issue:8

    Topics: Adrenal Gland Neoplasms; Adult; Aged; Aged, 80 and over; Cross-Over Studies; Diet; Dopamine; Female;

2009
Measurements of plasma methoxytyramine, normetanephrine, and metanephrine as discriminators of different hereditary forms of pheochromocytoma.
    Clinical chemistry, 2011, Volume: 57, Issue:3

    Topics: Adrenal Gland Neoplasms; Biomarkers, Tumor; Diagnosis, Differential; Dopamine; Humans; Metanephrine;

2011
Plasma methoxytyramine: a novel biomarker of metastatic pheochromocytoma and paraganglioma in relation to established risk factors of tumour size, location and SDHB mutation status.
    European journal of cancer (Oxford, England : 1990), 2012, Volume: 48, Issue:11

    Topics: Adrenal Gland Neoplasms; Adult; Biomarkers, Tumor; Dopamine; Female; Humans; Male; Middle Aged; Muta

2012
Role of the nitric oxide/cyclic GMP pathway and extracellular environment in the nitric oxide donor-induced increase in dopamine secretion from PC12 cells: a microdialysis in vitro study.
    Journal of neurochemistry, 2003, Volume: 86, Issue:6

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Ascorbic Acid; Calcium; Calcium Channel Blockers; Cell Surv

2003
Biochemical and clinical manifestations of dopamine-producing paragangliomas: utility of plasma methoxytyramine.
    The Journal of clinical endocrinology and metabolism, 2005, Volume: 90, Issue:4

    Topics: Adrenal Gland Neoplasms; Adult; Dihydroxyphenylalanine; Dopamine; Female; Humans; Male; Middle Aged;

2005
A new method for the simultaneous analysis of free and sulfoconjugated normetanephrine, metanephrine, and 3-methoxytyramine in human urine by HPLC with electrochemical detection.
    The Journal of laboratory and clinical medicine, 1984, Volume: 104, Issue:3

    Topics: Adrenal Gland Neoplasms; Adult; Chromatography, High Pressure Liquid; Dopamine; Epinephrine; Female;

1984
High-performance liquid chromatography with electrochemical detection for the simultaneous determination of the methoxylated amines, normetanephrine, metanephrine and 3-methoxytyramine, in urine.
    Journal of chromatography, 1983, May-13, Volume: 274

    Topics: Adolescent; Adult; Child; Child, Preschool; Chromatography, High Pressure Liquid; Dopamine; Electroc

1983
[Comparative secretory profiles of benign and malignant pheochromocytomas].
    Annales de chirurgie, 1994, Volume: 48, Issue:5

    Topics: Adrenal Gland Neoplasms; Dopamine; Epinephrine; Humans; Norepinephrine; Pheochromocytoma

1994
Evaluation of specific high-performance liquid-chromatographic determinations of urinary metanephrine and normetanephrine by comparison with isotope dilution mass spectrometry.
    Annals of clinical biochemistry, 2001, Volume: 38, Issue:Pt 6

    Topics: Adrenal Gland Neoplasms; Adult; Aged; Chromatography, High Pressure Liquid; Dopamine; Electrochemist

2001
Release and metabolism of dopamine in a clonal line of pheochromocytoma (PC12) cells exposed to fenthion.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1989, Volume: 13, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenal Gland Neoplasms; Animals; Dopamine; Fenthion; Homovanillic A

1989