3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide and Idiopathic Parkinson Disease

3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide has been researched along with Idiopathic Parkinson Disease in 54 studies

Research

Studies (54)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	33 (61.11)	18.2507
2000's	17 (31.48)	29.6817
2010's	4 (7.41)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Birgander, R; Edenbrandt, L; Forsgren, L; Jakobson Mo, S; Larsson, A; Linder, J; Riklund, K; Stenlund, H	1
Forsgren, L; Holmberg, H; Jakobson Mo, S; Larsson, A; Linder, J; Riklund, K	1
Dafotakis, M; Heinzel, A; Mohammadkhani Shali, S; Mottaghy, FM; Verburg, FA; Winz, OH	1
Antke, C; Beu, M; Müller, HW; Nikolaus, S; Schnitzler, A; Südmeyer, M; Wojtecki, L; Zizek, T	1
Colle, H; Temel, Y; van der Linden, C; Visser-Vandewalle, V	1
Leenders, KL	1
Abdo, WF; Bloem, BR; De Jong, D; Hendriks, JC; Horstink, MW; Kremer, BP; Verbeek, MM	1
Alcaraz, R; Atarés, B; Bilbao, G; Garibi, J; Gómez-Esteban, JC; Lambarri, I; Lezcano, E; Zarranz, JJ	1
Boesch, SM; Donnemiller, E; Müller, J; Poewe, W; Seppi, K; Weirich-Schwaiger, H; Wenning, GK	1
Costa, DC; Evans, AH; Gacinovic, S; Heales, S; Katzenschlager, R; Lee, P; Lees, AJ; O'sullivan, JD	1
Diem, A; Donnemiller, E; Esterhammer, R; Jaschke, W; Kremser, C; Poewe, W; Scherfler, C; Schocke, MF; Seppi, K; Wenning, GK	1
Hahn, K; Linke, R; Pöpperl, G; Radau, P; Tatsch, K	1
Amthauer, H; Felix, R; Gutberlet, M; Kivi, A; Klaffke, S; Klostermann, F; Kupsch, A; Marzinzik, F; Plotkin, M; Quill, S	1
Auburger, G; Barrero, F; Gispert, S; Hamscho, N; Kessler, KR; Menzel, C; Morales, B; Vives, F	1
Bloem, BR; Haaxma, CA; Horstink, MW; Oyen, WJ; Verstappen, CC	1
Barthel, H; Hesse, S; Luthardt, J; Meixensberger, J; Meyer, P; Oehlwein, C; Reupert, A; Sabri, O; Scherfler, C; Schneider, JP; Schwarz, J; Strecker, K; Wegner, F; Winkler, D	1
Coppola, R; Gorey, J; Hyde, TM; Jones, DW; Knable, MB; Lee, KS; Weinberger, DR	1
Antonini, A; Kirsch, CM; Leenders, KL; Oertel, WH; Schwarz, J; Tatsch, K	1
Hublin, C; Launes, J; Nikkinen, P; Partinen, M	1
Couch, MW; Devane, CL; Nadeau, SE; Shukla, SS	1
Bartenstein, P; Lerch, H; Masur, H; Oberwittler, C; Saur, HB; Schober, O	1
Berding, G; Dengler, R; Gratz, KF; Hundeshagen, H; Knoop, BO; Kolbe, H; Meyer, GJ	1
Cordes, M; Hierholzer, J; Poewe, W; Schelosky, L; Wissel, J	1
Arnold, G; Kirsch, CM; Oertel, WH; Ott, M; Schwarz, J; Tatsch, K; Trenkwalder, C	1
Böck, JC; Cordes, M; David, I; Hierholzer, J; Horowski, R; Poewe, W; Sander, B; Schelosky, L	1
Arnold, G; Gasser, T; Kirsch, CM; Oertel, WH; Schwarz, J; Tatsch, K	1
Cordes, I; Cordes, M; Eichstaedt, H; Felix, R; Hierholzer, J; Horowski, R; Poewe, W; Schelosky, L; Schmidt, D	1
Battistin, L; Borsato, N; Briani, C; Chierichetti, F; Dam, M; Ferlin, G; Pizzolato, G; Rossato, A; Saitta, B; Zanco, P	1
Bergström, K; Kuikka, JT; Länsimies, E; Laulumaa, V; Riekkinen, P; Soininen, H	1
Janssen, AG; Kuiper, MA; Speelman, JD; van Royen, E; Verhoeff, NF; Wolters, EC	1
Castellano, GC; Giobbe, D; Podio, V	1
Castelli, L; Cordes, M; Felix, R; Hierholzer, J; Poewe, W; Schelosky, L	1
Grundmann, M; Huber, G; Reiche, W	1
Battistin, L; Cagnin, A; Chierichetti, F; Dam, M; Fabbri, M; Ferlin, G; Pizzolato, G; Rossato, A	1
Oertel, WH; Schwarz, J; Tatsch, K	1
Hondl, N; Ladurner, G; Staffen, W; Trinka, E; Zenzmaier, R	1
Booij, J; Tissingh, G; van Royen, EA; Winogrodzka, A; Wolters, EC	1
Innis, RB	1
Baas, H; Baum, RP; Fischer, PA; Hertel, A; Hör, G; Maul, FD; Schreiner, M; Weppner, M	1
Arnold, G; Gasser, T; Oertel, WH; Schwarz, J; Tatsch, K	1
Donnemiller, E; Granata, R; Poewe, W; Riccabona, G; Wenning, GK	1
Cordes, M; Felix, R; Harisch, C; Hierholzer, J; Hosten, N; Keske, U; Mäurer, J; Poewe, W; Richter, W; Schelosky, L; Venz, S	1
Klimke, A; Larisch, R	1
Besnard, JC; Bodard, S; Chalon, S; Emond, P; Guilloteau, D; Thiercelin, C; Vilar, MP	1
Arnold, G; Kraft, E; Oertel, WH; Schwarz, J; Tatsch, K; Vogl, T	1
Fujita, M; Innis, RB; Kugaya, A	1
Eisensehr, I; Gildehaus, FJ; Linke, R; Noachtar, S; Schwarz, J; Tatsch, K	1
Ambrus, E; Csernay, L; Dibó, G; Pávics, L; Séra, T; Vécsei, L	1
Aurengo, A; El Fakhri, G; Kijewski, MF; Maksud, P; Moore, SC	1
Hwang, WJ; Shen, LH; Ting, G; Wey, SP; Yao, WJ	1
Barzen, G; Cordes, M; Felix, R; Henkes, H; Hierholzer, J; Horowski, R; Keske, U; Poewe, W; Schelosky, L	1
Arnold, G; Gasser, T; Kirsch, CM; Oertel, WH; Schwarz, J; Tatsch, K; Trenkwalder, C	1
Angelberger, P; Brücke, T; Deecke, L; Küfferle, B; Müller, C; Podreka, I; Topitz, A; Wenger, S	1
Kirsch, CM; Oertel, WH; Schwarz, J; Tatsch, K	1

Reviews

3 review(s) available for 3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide and Idiopathic Parkinson Disease

Article	Year
Significance of non-presynaptic SPECT tracer methods in Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society, 2003, Volume: 18 Suppl 7 Topics: Benzamides; Brain; Corpus Striatum; Diagnosis, Differential; Humans; Parkinson Disease; Pyrrolidines; Receptors, Dopamine D2; Receptors, Presynaptic; Regional Blood Flow; Sensitivity and Specificity; Technetium Tc 99m Exametazime; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon	2003
IBZM- and CIT-SPECT of the dopaminergic system in parkinsonism. Journal of neural transmission. Supplementum, 1997, Volume: 50 Topics: Benzamides; Brain; Cocaine; Diagnosis, Differential; Dopamine; Dopamine Antagonists; Humans; Iodine Radioisotopes; Parkinson Disease; Parkinson Disease, Secondary; Pyrrolidines; Receptors, Dopamine D2; Risk Factors; Tomography, Emission-Computed, Single-Photon	1997
Applications of SPECT imaging of dopaminergic neurotransmission in neuropsychiatric disorders. Annals of nuclear medicine, 2000, Volume: 14, Issue:1 Topics: Animals; Benzamides; Brain; Carrier Proteins; Cocaine; Disease Progression; Dopamine Plasma Membrane Transport Proteins; Humans; Iodine Radioisotopes; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Parkinson Disease; Pyrrolidines; Receptors, Dopamine D2; Schizophrenia; Synaptic Transmission; Tomography, Emission-Computed, Single-Photon	2000

Trials

8 trial(s) available for 3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide and Idiopathic Parkinson Disease

Article	Year
¹²³I-FP-Cit and 123I-IBZM SPECT uptake in a prospective normal material analysed with two different semiquantitative image evaluation tools. Nuclear medicine communications, 2013, Volume: 34, Issue:10 Topics: Adult; Aged; Benzamides; Biological Transport; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Image Processing, Computer-Assisted; Longitudinal Studies; Male; Middle Aged; Observer Variation; Parkinson Disease; Prospective Studies; Pyrrolidines; Reference Values; Synapses; Tomography, Emission-Computed, Single-Photon; Tropanes	2013
Diagnostic accuracy of combined FP-CIT, IBZM, and MIBG scintigraphy in the differential diagnosis of degenerative parkinsonism: a multidimensional statistical approach. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2011, Volume: 52, Issue:5 Topics: 3-Iodobenzylguanidine; Adult; Aged; Algorithms; Benzamides; Diagnosis, Differential; Humans; Middle Aged; Parkinson Disease; Parkinsonian Disorders; Pyrrolidines; Radionuclide Imaging; ROC Curve; Sensitivity and Specificity; Tropanes	2011
Diagnostic performance of a 3-D automated quantification method of dopamine D2 receptor SPECT studies in the differential diagnosis of parkinsonism. Nuclear medicine communications, 2005, Volume: 26, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Algorithms; Benzamides; Corpus Striatum; Diagnosis, Differential; Female; Humans; Image Enhancement; Image Interpretation, Computer-Assisted; Imaging, Three-Dimensional; Male; Middle Aged; Neurodegenerative Diseases; Parkinson Disease; Pyrrolidines; Radionuclide Imaging; Radiopharmaceuticals; Receptors, Dopamine D2; Reproducibility of Results; Sensitivity and Specificity	2005
Effects of subthalamic nucleus stimulation on striatal dopaminergic transmission in patients with Parkinson's disease within one-year follow-up. Journal of neurology, 2008, Volume: 255, Issue:7 Topics: Aged; Benzamides; Brain Mapping; Corpus Striatum; Deep Brain Stimulation; Dopamine; Female; Follow-Up Studies; Functional Laterality; Humans; Iodine Isotopes; Male; Middle Aged; Parkinson Disease; Pyrrolidines; Radionuclide Imaging; Subthalamic Nucleus; Tropanes	2008
Comparison of 123I-IBZM SPECT and 11C-raclopride PET findings in patients with parkinsonism. Nuclear medicine communications, 1994, Volume: 15, Issue:10 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Benzamides; Carbon Radioisotopes; Humans; Middle Aged; Parkinson Disease; Pyrrolidines; Raclopride; Receptors, Dopamine D2; Regression Analysis; Salicylamides; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon	1994
[Comparison of D2 receptor scintigraphy (123I-IBZM) with cerebral perfusion (99m-Tc-HMPAO) in extrapyramidal disorders]. Nuklearmedizin. Nuclear medicine, 1994, Volume: 33, Issue:5 Topics: Adult; Aged; Basal Ganglia; Basal Ganglia Diseases; Benzamides; Brain; Cerebellum; Cerebrovascular Circulation; Dopamine Antagonists; Frontal Lobe; Humans; Huntington Disease; Iodine Radioisotopes; Middle Aged; Organotechnetium Compounds; Oximes; Parkinson Disease; Parkinson Disease, Secondary; Pyrrolidines; Receptors, Dopamine D2; Technetium Tc 99m Exametazime; Tomography, Emission-Computed, Single-Photon	1994
123I-IBZM SPECT: reconstruction methodology and results in parkinsonism and dystonia. Nuklearmedizin. Nuclear medicine, 1994, Volume: 33, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Benzamides; Corpus Striatum; Dopamine Antagonists; Dystonia; Frontal Lobe; Humans; Iodine Radioisotopes; Middle Aged; Parkinson Disease; Pyrrolidines; Receptors, Dopamine D2; Tomography, Emission-Computed, Single-Photon	1994
[123]IBZM binding predicts dopaminergic responsiveness in patients with parkinsonism and previous dopaminomimetic therapy. Movement disorders : official journal of the Movement Disorder Society, 1997, Volume: 12, Issue:6 Topics: Adult; Aged; Apomorphine; Atrophy; Benzamides; Binding Sites; Cerebral Cortex; Dopamine; Dopamine Agonists; Dopamine Antagonists; Follow-Up Studies; Humans; Levodopa; Magnetic Resonance Imaging; Middle Aged; Parkinson Disease; Predictive Value of Tests; Putamen; Pyrrolidines; Receptors, Dopamine D2; Tomography, Emission-Computed, Single-Photon	1997

Other Studies

43 other study(ies) available for 3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide and Idiopathic Parkinson Disease

Article	Year
Pre- and postsynaptic dopamine SPECT in idiopathic Parkinsonian diseases: a follow-up study. BioMed research international, 2013, Volume: 2013 Topics: Aged; Benzamides; Case-Control Studies; Dopamine; Dopamine Plasma Membrane Transport Proteins; Follow-Up Studies; Humans; Multiple System Atrophy; Parkinson Disease; Parkinsonian Disorders; Pyrrolidines; Supranuclear Palsy, Progressive; Synapses; Time Factors; Tomography, Emission-Computed, Single-Photon	2013
Comparison of automatic versus manual procedures for the quantification of dopamine D2 receptor availability using I-123-IBZM-SPECT. Nuclear medicine communications, 2015, Volume: 36, Issue:11 Topics: Automation; Benzamides; Humans; Middle Aged; Parkinson Disease; Pyrrolidines; Receptors, Dopamine D2; Reference Standards; ROC Curve; Tomography, Emission-Computed, Single-Photon	2015
Bilateral high-frequency stimulation of the subthalamic nucleus in patients with multiple system atrophy--parkinsonism. Report of four cases. Journal of neurosurgery, 2003, Volume: 98, Issue:4 Topics: Activities of Daily Living; Aged; Antiparkinson Agents; Benzamides; Combined Modality Therapy; Contrast Media; Electric Stimulation Therapy; Female; Follow-Up Studies; Functional Laterality; Humans; Levodopa; Male; Middle Aged; Multiple System Atrophy; Parkinson Disease; Pyrrolidines; Subthalamic Nucleus; Tomography, Emission-Computed, Single-Photon; Treatment Outcome	2003
Cerebrospinal fluid analysis differentiates multiple system atrophy from Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society, 2004, Volume: 19, Issue:5 Topics: Adult; Aged; Benzamides; Brain; Diagnosis, Differential; Electromyography; Enzyme-Linked Immunosorbent Assay; Female; Follow-Up Studies; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Iodine Radioisotopes; Lactic Acid; Male; Methoxyhydroxyphenylglycol; Multiple System Atrophy; NAD; Parkinson Disease; Pyrrolidines; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed	2004
Parkinson's disease-like presentation of multiple system atrophy with poor response to STN stimulation: a clinicopathological case report. Movement disorders : official journal of the Movement Disorder Society, 2004, Volume: 19, Issue:8 Topics: Antiparkinson Agents; Benzamides; Dopamine Antagonists; Electric Stimulation Therapy; Follow-Up Studies; Humans; Immunohistochemistry; Levodopa; Male; Middle Aged; Multiple System Atrophy; Nerve Tissue Proteins; Neurons; Parkinson Disease; Pyrrolidines; Retrospective Studies; Staining and Labeling; Subthalamic Nucleus; Synucleins; Tomography, Emission-Computed, Single-Photon	2004
Abnormalities of dopaminergic neurotransmission in SCA2: a combined 123I-betaCIT and 123I-IBZM SPECT study. Movement disorders : official journal of the Movement Disorder Society, 2004, Volume: 19, Issue:11 Topics: Adult; Basal Ganglia; Benzamides; Cerebellum; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dystonic Disorders; Female; Humans; Iodine Radioisotopes; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Parkinson Disease; Parkinsonian Disorders; Pyrrolidines; Receptors, Dopamine D2; Reference Values; Spinocerebellar Ataxias; Synaptic Transmission; Tomography, Emission-Computed, Single-Photon	2004
L-Dopa-responsive Parkinson's syndrome in association with phenylketonuria: In vivo dopamine transporter and D2 receptor findings. Movement disorders : official journal of the Movement Disorder Society, 2004, Volume: 19, Issue:10 Topics: Adult; Antiparkinson Agents; Benzamides; Brain; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Iodine Radioisotopes; Levodopa; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Parkinson Disease; Phenylketonurias; Pyrrolidines; Radiopharmaceuticals; Receptors, Dopamine D2; Tomography, Emission-Computed, Single-Photon; Tropanes	2004
Comparison of diffusion-weighted imaging and [123I]IBZM-SPECT for the differentiation of patients with the Parkinson variant of multiple system atrophy from those with Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society, 2004, Volume: 19, Issue:12 Topics: Basal Ganglia; Benzamides; Contrast Media; Corpus Striatum; Cross-Sectional Studies; Diffusion Magnetic Resonance Imaging; Follow-Up Studies; Frontal Lobe; Humans; Middle Aged; Multiple System Atrophy; Parkinson Disease; Predictive Value of Tests; Pyrrolidines; Sensitivity and Specificity; Tomography, Emission-Computed, Single-Photon	2004
Imaging of dopamine transporters and D2 receptors in vascular parkinsonism: a report of four cases. Journal of neural transmission (Vienna, Austria : 1996), 2005, Volume: 112, Issue:10 Topics: Aged; Aged, 80 and over; Benzamides; Carbon Radioisotopes; Cerebrovascular Circulation; Dementia, Vascular; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Iodine Radioisotopes; Male; Parkinson Disease; Pyrrolidines; Receptors, Dopamine D2; Tomography, Emission-Computed, Single-Photon; Tropanes	2005
Dopaminergic function in a family with the PARK6 form of autosomal recessive Parkinson's syndrome. Journal of neural transmission (Vienna, Austria : 1996), 2005, Volume: 112, Issue:10 Topics: Adult; Benzamides; Carbon Radioisotopes; Corpus Striatum; Dopamine; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Family Health; Female; Genes, Recessive; Humans; Iodine Radioisotopes; Male; Middle Aged; Parkinson Disease; Protein Kinases; Pyrrolidines; Siblings; Substantia Nigra; Tomography, Emission-Computed, Single-Photon; Tropanes	2005
Diagnostic value of asymmetric striatal D2 receptor upregulation in Parkinson's disease: an [123I]IBZM and [123I]FP-CIT SPECT study. European journal of nuclear medicine and molecular imaging, 2007, Volume: 34, Issue:4 Topics: Benzamides; Biomarkers; Corpus Striatum; Female; Humans; Male; Middle Aged; Parkinson Disease; Pyrrolidines; Radiography; Radiopharmaceuticals; Receptors, Dopamine D2; Reproducibility of Results; Sensitivity and Specificity; Tomography, Emission-Computed, Single-Photon; Tropanes; Up-Regulation	2007
Lateralized differences in iodine-123-IBZM uptake in the basal ganglia in asymmetric Parkinson's disease. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1995, Volume: 36, Issue:7 Topics: Adult; Aged; Basal Ganglia; Benzamides; Cerebrovascular Circulation; Female; Humans; Iodine Radioisotopes; Male; Middle Aged; Organotechnetium Compounds; Oximes; Parkinson Disease; Pyrrolidines; Receptors, Dopamine D2; Technetium Tc 99m Exametazime; Tomography, Emission-Computed, Single-Photon	1995
Dopamine D2-receptors in human narcolepsy: a SPECT study with 123I-IBZM. Acta neurologica Scandinavica, 1994, Volume: 90, Issue:3 Topics: Adult; Benzamides; Contrast Media; Corpus Striatum; Dominance, Cerebral; Female; Frontal Lobe; Humans; Iodine Radioisotopes; Male; Middle Aged; Narcolepsy; Parkinson Disease; Pyrrolidines; Receptors, Dopamine D2; Sleep Stages; Tomography, Emission-Computed, Single-Photon	1994
Regional analysis of D2 dopamine receptors in Parkinson's disease using SPECT and iodine-123-iodobenzamide. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1995, Volume: 36, Issue:3 Topics: Aged; Aged, 80 and over; Benzamides; Brain; Female; Humans; Iodine Radioisotopes; Male; Middle Aged; Parkinson Disease; Pyrrolidines; Receptors, Dopamine D2; Regression Analysis; Tomography, Emission-Computed, Single-Photon	1995
Correlation of clinical response in apomorphine test with D2-receptor status as demonstrated by 123I IBZM-SPECT. Movement disorders : official journal of the Movement Disorder Society, 1993, Volume: 8, Issue:4 Topics: Adult; Aged; Apomorphine; Basal Ganglia; Benzamides; Binding Sites; Brain; Corpus Striatum; Female; Humans; Male; Middle Aged; Parkinson Disease; Pyrrolidines; Receptors, Dopamine D2; Tomography, Emission-Computed, Single-Photon	1993
123I-iodobenzamide-SPECT in 83 patients with de novo parkinsonism. Neurology, 1993, Volume: 43, Issue:12 Suppl 6 Topics: Adult; Aged; Aged, 80 and over; Benzamides; Brain; Humans; Iodine Radioisotopes; Middle Aged; Parkinson Disease; Pyrrolidines; Receptors, Dopamine D2; Tomography, Emission-Computed, Single-Photon	1993
[The differential diagnosis of Parkinson diseases--123I-IBZM-SPECT vs. the apomorphine test]. RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 1993, Volume: 159, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Apomorphine; Basal Ganglia Diseases; Benzamides; Contrast Media; Diagnosis, Differential; Dopamine D2 Receptor Antagonists; Female; Humans; Iodine Radioisotopes; Male; Middle Aged; Parkinson Disease; Pyrrolidines; Time Factors; Tomography, Emission-Computed, Single-Photon	1993
IBZM-SPECT as predictor for dopamimetic responsiveness of patients with de novo parkinsonian syndrome. Advances in neurology, 1993, Volume: 60 Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Apomorphine; Benzamides; Corpus Striatum; Dopamine D2 Receptor Antagonists; Female; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Prospective Studies; Pyrrolidines; Receptors, Dopamine D1; Receptors, Dopamine D2; Tomography, Emission-Computed, Single-Photon	1993
IBZM-SPECT imaging in Parkinson's disease. Quantification of binding ratios from sequential SPECT measurements in patients and controls. Advances in neurology, 1993, Volume: 60 Topics: Aged; Aged, 80 and over; Antiparkinson Agents; Benzamides; Corpus Striatum; Dopamine D2 Receptor Antagonists; Female; Humans; Male; Middle Aged; Parkinson Disease; Pyrrolidines; Receptors, Dopamine D2; Tomography, Emission-Computed, Single-Photon	1993
Dopamine receptor SPET imaging in Parkinson's disease: a [123I]-IBZM and [99mTc]-HM-PAO study. European neurology, 1993, Volume: 33, Issue:2 Topics: Adult; Aged; Basal Ganglia; Benzamides; Female; Humans; Levodopa; Male; Middle Aged; Organotechnetium Compounds; Oximes; Parkinson Disease; Pyrrolidines; Receptors, Dopamine; Technetium Tc 99m Exametazime; Tomography, Emission-Computed, Single-Photon	1993
Imaging of D2 dopamine receptors of patients with Parkinson's disease using single photon emission computed tomography and iodobenzamide I 123. Archives of neurology, 1993, Volume: 50, Issue:5 Topics: Aged; Benzamides; Corpus Striatum; Dopamine D2 Receptor Antagonists; Female; Humans; Male; Middle Aged; Parkinson Disease; Pyrrolidines; Receptors, Dopamine D2; Tomography, Emission-Computed, Single-Photon	1993
Multiple system atrophy and progressive supranuclear palsy. Diminished striatal D2 dopamine receptor activity demonstrated by 123I-IBZM single photon emission computed tomography. Archives of neurology, 1993, Volume: 50, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Atrophy; Benzamides; Central Nervous System; Dopamine D2 Receptor Antagonists; Humans; Middle Aged; Parkinson Disease; Pyrrolidines; Receptors, Dopamine D2; Supranuclear Palsy, Progressive; Tomography, Emission-Computed, Single-Photon	1993
Dopamine D2 receptor imaging with SPECT using IBZM in 16 patients with Parkinson disease. Italian journal of neurological sciences, 1993, Volume: 14, Issue:2 Topics: Aged; Benzamides; Contrast Media; Female; Humans; Male; Parkinson Disease; Pyrrolidines; Radioligand Assay; Receptors, Dopamine D2; Tomography, Emission-Computed, Single-Photon	1993
[Cerebral SPECT with iodine-123 IBZM in patients with extrapyramidal system disorders: the evaluation of its sensitivity in therapy with dopaminergic drugs]. La Radiologia medica, 1996, Volume: 91, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Apomorphine; Basal Ganglia Diseases; Benzamides; Brain; Contrast Media; Dopamine Agonists; Female; Humans; Iodine Radioisotopes; Male; Middle Aged; Parkinson Disease; Pyrrolidines; Tomography, Emission-Computed, Single-Photon	1996
[Dopamine (D2) receptor SPECT with 123I-iodobenzamide (IBZM) in diagnosis of Parkinson syndrome]. Der Radiologe, 1995, Volume: 35, Issue:11 Topics: Adult; Aged; Aged, 80 and over; Benzamides; Diagnosis, Differential; Dopamine Antagonists; Female; Humans; Iodine Radioisotopes; Male; Middle Aged; Nerve Degeneration; Parkinson Disease; Parkinson Disease, Secondary; Pyrrolidines; Receptors, Dopamine D2; Tomography, Emission-Computed, Single-Photon	1995
Alterations of striatal dopamine D2 receptors contribute to deteriorated response to L-dopa in Parkinson's disease: a [123I]-IBZM SPET study. Journal of neural transmission. Supplementum, 1995, Volume: 45 Topics: Adult; Aged; Antiparkinson Agents; Benzamides; Case-Control Studies; Corpus Striatum; Dopamine Agents; Female; Humans; Iodine Radioisotopes; Levodopa; Male; Middle Aged; Parkinson Disease; Pyrrolidines; Receptors, Dopamine D2; Tomography, Emission-Computed, Single-Photon	1995
Iodine-123-iodobenzamide binding in parkinsonism: reduction by dopamine agonists but not L-Dopa. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1996, Volume: 37, Issue:7 Topics: Antiparkinson Agents; Benzamides; Brain; Case-Control Studies; Contrast Media; Dopamine Agonists; Dopamine Antagonists; Humans; Levodopa; Middle Aged; Parkinson Disease; Prospective Studies; Pyrrolidines; Time Factors; Tomography, Emission-Computed, Single-Photon	1996
SPET investigations in extrapyramidal diseases using specific ligands. Nuclear medicine communications, 1997, Volume: 18, Issue:2 Topics: Adult; Aged; Benzamides; Brain; Cocaine; Dopamine Antagonists; Hepatolenticular Degeneration; Humans; Huntington Disease; Iodine Radioisotopes; Male; Middle Aged; Movement Disorders; Parkinson Disease; Pyrrolidines; Receptors, Dopamine D2; Reference Values; Supranuclear Palsy, Progressive; Tissue Distribution; Tomography, Emission-Computed, Single-Photon	1997
Single photon emission computed tomography imaging of dopaminergic function: presynaptic transporter, postsynaptic receptor, and "intrasynaptic" transmitter. Advances in pharmacology (San Diego, Calif.), 1998, Volume: 42 Topics: Animals; Benzamides; Brain; Carrier Proteins; Cocaine; Dopamine; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Humans; Iodine Radioisotopes; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Parkinson Disease; Presynaptic Terminals; Primates; Pyrrolidines; Receptors, Dopamine; Reference Values; Schizophrenia; Serotonin; Serotonin Plasma Membrane Transport Proteins; Synapses; Tomography, Emission-Computed, Single-Photon	1998
Quantification of IBZM dopamine receptor SPET in de novo Parkinson patients before and during therapy. Nuclear medicine communications, 1997, Volume: 18, Issue:9 Topics: Adult; Aged; Antiparkinson Agents; Basal Ganglia; Benzamides; Female; Frontal Lobe; Humans; Iodine Radioisotopes; Male; Middle Aged; Parkinson Disease; Pyrrolidines; Receptors, Dopamine D2; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon	1997
123I-beta-CIT and 123I-IBZM-SPECT scanning in levodopa-naive Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society, 1998, Volume: 13, Issue:3 Topics: Aged; Benzamides; Carrier Proteins; Cerebellum; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Iodine Radioisotopes; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Parkinson Disease; Pyrrolidines; Receptors, Dopamine D2; Tomography, Emission-Computed, Single-Photon	1998
Loss of dopamine-D2 receptor binding sites in Parkinsonian plus syndromes. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1998, Volume: 39, Issue:6 Topics: Adult; Aged; Benzamides; Binding Sites; Contrast Media; Corpus Striatum; Female; Humans; Iodine Radioisotopes; Male; Middle Aged; Multiple System Atrophy; Observer Variation; Olivopontocerebellar Atrophies; Parkinson Disease; Pyrrolidines; Receptors, Dopamine D2; Reproducibility of Results; Supranuclear Palsy, Progressive; Syndrome; Time Factors; Tomography, Emission-Computed, Single-Photon	1998
[Clinical impact of cerebral dopamine-D2 receptor scintigraphy]. Nuklearmedizin. Nuclear medicine, 1998, Volume: 37, Issue:7 Topics: Benzamides; Brain; Carbon Radioisotopes; Fluorine Radioisotopes; Humans; Iodine Radioisotopes; Mental Disorders; Parkinson Disease; Pyrrolidines; Receptors, Dopamine D2; Schizophrenia; Substance-Related Disorders; Tissue Distribution; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon	1998
Time course of changes in striatal dopamine transporters and D2 receptors with specific iodinated markers in a rat model of Parkinson's disease. Synapse (New York, N.Y.), 1999, Volume: 31, Issue:2 Topics: Animals; Benzamides; Carrier Proteins; Corpus Striatum; Dopamine; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Iodine Radioisotopes; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Nortropanes; Parkinson Disease; Pyrrolidines; Radiopharmaceuticals; Rats; Rats, Wistar; Receptors, Dopamine D2; Time Factors; Tomography, Emission-Computed, Single-Photon	1999
Relative quantification of signal on T2-weighted images in the basal ganglia: limited value in differential diagnosis of patients with parkinsonism. Neuroradiology, 1999, Volume: 41, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Antiparkinson Agents; Apomorphine; Basal Ganglia; Benzamides; Contrast Media; Diagnosis, Differential; Dopamine Antagonists; Humans; Iodine Radioisotopes; Magnetic Resonance Imaging; Middle Aged; Parkinson Disease; Prospective Studies; Pyrrolidines; Tomography, Emission-Computed, Single-Photon	1999
Reduced striatal dopamine transporters in idiopathic rapid eye movement sleep behaviour disorder. Comparison with Parkinson's disease and controls. Brain : a journal of neurology, 2000, Volume: 123 ( Pt 6) Topics: Adult; Aged; Benzamides; Carrier Proteins; Corpus Striatum; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Eye Movements; Humans; Iodine Radioisotopes; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Parkinson Disease; Presynaptic Terminals; Pyrrolidines; Receptors, Dopamine D2; Sleep Wake Disorders; Sleep, REM; Tomography, Emission-Computed, Single-Photon; Tropanes	2000
[Initial experiences with 123-Iodine-IBZM neuroreceptor scintigraphy in extrapyramidal disorders]. Orvosi hetilap, 2000, May-14, Volume: 141, Issue:20 Topics: Adult; Aged; Benzamides; Contrast Media; Corpus Striatum; Female; Frontal Lobe; Humans; Iodine Radioisotopes; Male; Middle Aged; Parkinson Disease; Pyrrolidines; Sensory Receptor Cells; Tomography, Emission-Computed, Single-Photon	2000
Absolute activity quantitation in simultaneous 123I/99mTc brain SPECT. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2001, Volume: 42, Issue:2 Topics: Alzheimer Disease; Benzamides; Brain; Cerebellum; Cerebral Cortex; Cerebrovascular Circulation; Corpus Callosum; Humans; Iodine Radioisotopes; Monte Carlo Method; Neural Networks, Computer; Parkinson Disease; Phantoms, Imaging; Putamen; Pyrrolidines; Radiopharmaceuticals; Sensitivity and Specificity; Technetium Tc 99m Exametazime; Tomography, Emission-Computed, Single-Photon	2001
Downregulation of striatal dopamine D2 receptors in advanced Parkinson's disease contributes to the development of motor fluctuation. European neurology, 2002, Volume: 47, Issue:2 Topics: Adult; Aged; Benzamides; Corpus Striatum; Female; Humans; Iodine Radioisotopes; Levodopa; Male; Middle Aged; Motor Skills; Neurologic Examination; Parkinson Disease; Pyrrolidines; Receptors, Dopamine D2; Synaptic Transmission; Tomography, Emission-Computed, Single-Photon	2002
[The determination of cerebral dopamine (D2) receptor density by using 123I-IBZM-SPECT in Parkinson disease patients]. RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 1992, Volume: 157, Issue:4 Topics: Aged; Benzamides; Brain; Color; Female; Humans; Iodine Radioisotopes; Levodopa; Male; Middle Aged; Parkinson Disease; Protein Binding; Pyrrolidines; Receptors, Dopamine D2; Software; Tomography, Emission-Computed, Single-Photon	1992
123I-iodobenzamide-SPECT predicts dopaminergic responsiveness in patients with de novo parkinsonism. Neurology, 1992, Volume: 42, Issue:3 Pt 1 Topics: Adult; Aged; Aged, 80 and over; Apomorphine; Benzamides; Humans; Iodine Radioisotopes; Levodopa; Middle Aged; Parkinson Disease; Pyrrolidines; Receptors, Dopamine; Tomography, Emission-Computed, Single-Photon	1992
Dopamine D2 receptor imaging with SPECT: studies in different neuropsychiatric disorders. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1991, Volume: 11, Issue:2 Topics: Adult; Aged; Aging; Antipsychotic Agents; Benzamides; Brain Diseases; Cerebellum; Corpus Striatum; Frontal Lobe; Humans; Huntington Disease; Iodine Radioisotopes; Levodopa; Middle Aged; Parkinson Disease; Pyrrolidines; Receptors, Dopamine; Receptors, Dopamine D2; Stereoisomerism; Tissue Distribution; Tomography, Emission-Computed, Single-Photon	1991
SPECT imaging of dopamine D2 receptors with 123I-IBZM: initial experience in controls and patients with Parkinson's syndrome and Wilson's disease. Nuclear medicine communications, 1991, Volume: 12, Issue:8 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Benzamides; Female; Hepatolenticular Degeneration; Humans; Male; Middle Aged; Parkinson Disease; Pyrrolidines; Receptors, Dopamine; Receptors, Dopamine D2; Tomography, Emission-Computed, Single-Photon	1991